-
1
-
-
0032909752
-
Interleukin-18 and interleukin-1 beta: Two cytokine substrates for ICE (caspase-1)
-
Fantuzzi G, Dinarello CA. Interleukin-18 and interleukin-1 beta: two cytokine substrates for ICE (caspase-1). J Clin Immunol. 1999;19(1):1-11.
-
(1999)
J Clin Immunol.
, vol.19
, Issue.1
, pp. 1-11
-
-
Fantuzzi, G.1
Dinarello, C.A.2
-
3
-
-
79952393266
-
The inflammasomes in health and disease: From genetics to molecular mechanisms of autoinflammation and beyond
-
Conforti-Andreoni C, Ricciardi-Castagnoli P, Mortellaro A. The inflammasomes in health and disease: from genetics to molecular mechanisms of autoinflammation and beyond. Cell Mol Immunol. 2011;8(2):135-45.
-
(2011)
Cell Mol Immunol.
, vol.8
, Issue.2
, pp. 135-145
-
-
Conforti-Andreoni, C.1
Ricciardi-Castagnoli, P.2
Mortellaro, A.3
-
4
-
-
79953046719
-
The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases
-
Davis BK, Wen H, Ting JP. The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases. Annu Rev Immunol. 2010; 29:707-35.
-
(2010)
Annu Rev Immunol.
, vol.29
, pp. 707-735
-
-
Davis, B.K.1
Wen, H.2
Ting, J.P.3
-
5
-
-
0035958867
-
Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1
-
Poyet JL, Srinivasula SM, Tnani M, Razmara M, Fernandes-Alnemri T, Alnemri ES. Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1. J Biol Chem. 2001;276(30):28309-13.
-
(2001)
J Biol Chem.
, vol.276
, Issue.30
, pp. 28309-28313
-
-
Poyet, J.L.1
Srinivasula, S.M.2
Tnani, M.3
Razmara, M.4
Fernandes-Alnemri, T.5
Alnemri, E.S.6
-
6
-
-
33847376042
-
Reconstituted NALP1 inflammasome reveals twostep mechanism of caspase-1 activation
-
Faustin B, Lartigue L, Bruey JM, Luciano F, Sergienko E, Bailly-Maitre B, et al. Reconstituted NALP1 inflammasome reveals twostep mechanism of caspase-1 activation. Mol Cell. 2007;25(5):713-24.
-
(2007)
Mol Cell.
, vol.25
, Issue.5
, pp. 713-724
-
-
Faustin, B.1
Lartigue, L.2
Bruey, J.M.3
Luciano, F.4
Sergienko, E.5
Bailly-Maitre, B.6
-
7
-
-
0030698127
-
The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases
-
Roy N, Deveraux QL, Takahashi R, Salvesen GS, Reed JC. The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases. EMBO J. 1997;16(23):6914-25.
-
(1997)
EMBO J.
, vol.16
, Issue.23
, pp. 6914-6925
-
-
Roy, N.1
Deveraux, Q.L.2
Takahashi, R.3
Salvesen, G.S.4
Reed, J.C.5
-
8
-
-
80053379974
-
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
-
Kofoed EM, Vance RE. Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity. Nature. 2011;477(7366):592-5.
-
(2011)
Nature.
, vol.477
, Issue.7366
, pp. 592-595
-
-
Kofoed, E.M.1
Vance, R.E.2
-
9
-
-
80053349020
-
The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus
-
Zhao Y, Yang J, Shi J, Gong YN, Lu Q, Xu H, et al. The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. Nature. 2011;477(7366):596-600.
-
(2011)
Nature.
, vol.477
, Issue.7366
, pp. 596-600
-
-
Zhao, Y.1
Yang, J.2
Shi, J.3
Gong, Y.N.4
Lu, Q.5
Xu, H.6
-
10
-
-
0036671894
-
The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
Martinon F, Burns K, Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell. 2002;10(2):417-26.
-
(2002)
Mol Cell.
, vol.10
, Issue.2
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
11
-
-
70249138036
-
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
-
Bauernfeind FG, Horvath G, Stutz A, Alnemri ES, MacDonald K, Speert D, et al. Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression. J Immunol. 2009;183(2):787-91.
-
(2009)
J Immunol.
, vol.183
, Issue.2
, pp. 787-791
-
-
Bauernfeind, F.G.1
Horvath, G.2
Stutz, A.3
Alnemri, E.S.4
McDonald, K.5
Speert, D.6
-
12
-
-
34548027736
-
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
-
Petrilli V, Papin S, Dostert C, Mayor A, Martinon F, Tschopp J. Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ. 2007;14(9):1583-9.
-
(2007)
Cell Death Differ.
, vol.14
, Issue.9
, pp. 1583-1589
-
-
Petrilli, V.1
Papin, S.2
Dostert, C.3
Mayor, A.4
Martinon, F.5
Tschopp, J.6
-
13
-
-
43249125839
-
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
-
Dostert C, Petrilli V, Van Bruggen R, Steele C, Mossman BT, Tschopp J. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science. 2008;320(5876):674-7.
-
(2008)
Science.
, vol.320
, Issue.5876
, pp. 674-677
-
-
Dostert, C.1
Petrilli, V.2
Van Bruggen, R.3
Steele, C.4
Mossman, B.T.5
Tschopp, J.6
-
14
-
-
34047261260
-
ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages
-
Cruz CM, Rinna A, Forman HJ, Ventura AL, Persechini PM, Ojcius DM. ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages. J Biol Chem. 2007;282(5):2871-9.
-
(2007)
J Biol Chem.
, vol.282
, Issue.5
, pp. 2871-2879
-
-
Cruz, C.M.1
Rinna, A.2
Forman, H.J.3
Ventura, A.L.4
Persechini, P.M.5
Ojcius, D.M.6
-
15
-
-
70049101754
-
Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases
-
Shio MT, Eisenbarth SC, Savaria M, Vinet AF, Bellemare MJ, Harder KW, et al. Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases. PLoS Pathog. 2009;5(8):e1000559.
-
(2009)
PLoS Pathog.
, vol.5
, Issue.8
-
-
Shio, M.T.1
Eisenbarth, S.C.2
Savaria, M.3
Vinet, A.F.4
Bellemare, M.J.5
Harder, K.W.6
-
16
-
-
79960542894
-
Cutting edge: Reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome
-
Bauernfeind F, Bartok E, Rieger A, Franchi L, Nunez G, Hornung V. Cutting edge: Reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome. J Immunol. 2011;187(2):613-7.
-
(2011)
J Immunol.
, vol.187
, Issue.2
, pp. 613-617
-
-
Bauernfeind, F.1
Bartok, E.2
Rieger, A.3
Franchi, L.4
Nunez, G.5
Hornung, V.6
-
17
-
-
47849097202
-
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
-
Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, Rock KL, et al. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol. 2008;9(8):847-56.
-
(2008)
Nat Immunol.
, vol.9
, Issue.8
, pp. 847-856
-
-
Hornung, V.1
Bauernfeind, F.2
Halle, A.3
Samstad, E.O.4
Kono, H.5
Rock, K.L.6
-
18
-
-
47849085872
-
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta
-
Halle A, Hornung V, Petzold GC, Stewart CR, Monks BG, Reinheckel T, et al. The NALP3 inflammasome is involved in the innate immune response to amyloid-beta. Nat Immunol. 2008;9(8):857-65.
-
(2008)
Nat Immunol.
, vol.9
, Issue.8
, pp. 857-865
-
-
Halle, A.1
Hornung, V.2
Petzold, G.C.3
Stewart, C.R.4
Monks, B.G.5
Reinheckel, T.6
-
19
-
-
77951800951
-
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
-
Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG, et al. NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature. 2010;464(7293):1357-61.
-
(2010)
Nature.
, vol.464
, Issue.7293
, pp. 1357-1361
-
-
Duewell, P.1
Kono, H.2
Rayner, K.J.3
Sirois, C.M.4
Vladimer, G.5
Bauernfeind, F.G.6
-
20
-
-
77955356552
-
Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: A novel link between cholesterol metabolism and inflammation
-
Rajamaki K, Lappalainen J, Oorni K, Valimaki E, Matikainen S, Kovanen PT, et al. Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation. PLoS One. 2010;5(7):e11765.
-
(2010)
PLoS One.
, vol.5
, Issue.7
-
-
Rajamaki, K.1
Lappalainen, J.2
Oorni, K.3
Valimaki, E.4
Matikainen, S.5
Kovanen, P.T.6
-
21
-
-
79955776183
-
A Yersinia effector with enhanced inhibitory activity on the NF-kappaB pathway activates the NLRP3/ASC/caspase-1 inflammasome in macrophages
-
Zheng Y, Lilo S, Brodsky IE, Zhang Y, Medzhitov R, Marcu KB, et al. A Yersinia effector with enhanced inhibitory activity on the NF-kappaB pathway activates the NLRP3/ASC/caspase-1 inflammasome in macrophages. PLoS Pathog. 2011;7(4):e1002026.
-
(2011)
PLoS Pathog.
, vol.7
, Issue.4
-
-
Zheng, Y.1
Lilo, S.2
Brodsky, I.E.3
Zhang, Y.4
Medzhitov, R.5
Marcu, K.B.6
-
22
-
-
77954958602
-
Aspergillus fumigatus stimulates the NLRP3 inflammasome through a pathway requiring ROS production and the Syk tyrosine kinase
-
Said-Sadier N, Padilla E, Langsley G, Ojcius DM. Aspergillus fumigatus stimulates the NLRP3 inflammasome through a pathway requiring ROS production and the Syk tyrosine kinase. PLoS One. 2010;5(4):e10008.
-
(2010)
PLoS One.
, vol.5
, Issue.4
-
-
Said-Sadier, N.1
Padilla, E.2
Langsley, G.3
Ojcius, D.M.4
-
23
-
-
34547101484
-
Differential requirement of P2X7 receptor and intracellular K+ for caspase-1 activation induced by intracellular and extracellular bacteria
-
Franchi L, Kanneganti TD, Dubyak GR, Nunez G. Differential requirement of P2X7 receptor and intracellular K+ for caspase-1 activation induced by intracellular and extracellular bacteria. J Biol Chem. 2007;282(26):18810-8.
-
(2007)
J Biol Chem.
, vol.282
, Issue.26
, pp. 18810-18818
-
-
Franchi, L.1
Kanneganti, T.D.2
Dubyak, G.R.3
Nunez, G.4
-
24
-
-
34548031870
-
The pyroptosome: A supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
-
Fernandes-Alnemri T, Wu J, Yu JW, Datta P, Miller B, Jankowski W, et al. The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation. Cell Death Differ. 2007;14(9):1590-604.
-
(2007)
Cell Death Differ.
, vol.14
, Issue.9
, pp. 1590-1604
-
-
Fernandes-Alnemri, T.1
Wu, J.2
Yu, J.W.3
Datta, P.4
Miller, B.5
Jankowski, W.6
-
25
-
-
65449134828
-
Asc and Ipaf Inflammasomes direct distinct pathways for caspase-1 activation in response to Legionella pneumophila
-
Case CL, Shin S, Roy CR. Asc and Ipaf Inflammasomes direct distinct pathways for caspase-1 activation in response to Legionella pneumophila. Infect Immun. 2009;77(5):1981-91.
-
(2009)
Infect Immun.
, vol.77
, Issue.5
, pp. 1981-1991
-
-
Case, C.L.1
Shin, S.2
Roy, C.R.3
-
26
-
-
41949127121
-
Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms
-
Fink SL, Bergsbaken T, Cookson BT. Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms. Proc Nat Acad Sci USA. 2008;105(11):4312-7.
-
(2008)
Proc Nat Acad Sci USA.
, vol.105
, Issue.11
, pp. 4312-4317
-
-
Fink, S.L.1
Bergsbaken, T.2
Cookson, B.T.3
-
27
-
-
77951231332
-
The role of potassium in inflammasome activation by bacteria
-
Arlehamn CS, Petrilli V, Gross O, Tschopp J, Evans TJ. The role of potassium in inflammasome activation by bacteria. J Biol Chem. 2010;285(14):10508-18.
-
(2010)
J Biol Chem.
, vol.285
, Issue.14
, pp. 10508-10518
-
-
Arlehamn, C.S.1
Petrilli, V.2
Gross, O.3
Tschopp, J.4
Evans, T.J.5
-
28
-
-
75649096002
-
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
-
Zhou R, Tardivel A, Thorens B, Choi I, Tschopp J. Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nat Immunol. 2010;11(2):136-40.
-
(2010)
Nat Immunol.
, vol.11
, Issue.2
, pp. 136-140
-
-
Zhou, R.1
Tardivel, A.2
Thorens, B.3
Choi, I.4
Tschopp, J.5
-
29
-
-
33846024748
-
Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf
-
Amer A, Franchi L, Kanneganti TD, Body-Malapel M, Ozoren N, Brady G, et al. Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf. J Biol Chem. 2006;281(46):35217-23.
-
(2006)
J Biol Chem.
, vol.281
, Issue.46
, pp. 35217-35223
-
-
Amer, A.1
Franchi, L.2
Kanneganti, T.D.3
Body-Malapel, M.4
Ozoren, N.5
Brady, G.6
-
30
-
-
33645843633
-
Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection
-
Molofsky AB, Byrne BG, Whitfield NN, Madigan CA, Fuse ET, Tateda K, et al. Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection. J Exp Med. 2006;203(4):1093-104.
-
(2006)
J Exp Med.
, vol.203
, Issue.4
, pp. 1093-1104
-
-
Molofsky, A.B.1
Byrne, B.G.2
Whitfield, N.N.3
Madigan, C.A.4
Fuse, E.T.5
Tateda, K.6
-
31
-
-
33645791082
-
Flagellin-deficient Legionella mutants evade caspase-1-and Naip5-mediated macrophage immunity
-
Ren T, Zamboni DS, Roy CR, Dietrich WF, Vance RE. Flagellin-deficient Legionella mutants evade caspase-1-and Naip5-mediated macrophage immunity. PLoS Pathog. 2006;2(3):e18.
-
(2006)
PLoS Pathog.
, vol.2
, Issue.3
-
-
Ren, T.1
Zamboni, D.S.2
Roy, C.R.3
Dietrich, W.F.4
Vance, R.E.5
-
32
-
-
33744464740
-
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages
-
Franchi L, Amer A, Body-Malapel M, Kanneganti TD, Ozoren N, Jagirdar R, et al. Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages. Nat Immunol. 2006;7(6):576-82.
-
(2006)
Nat Immunol.
, vol.7
, Issue.6
, pp. 576-582
-
-
Franchi, L.1
Amer, A.2
Body-Malapel, M.3
Kanneganti, T.D.4
Ozoren, N.5
Jagirdar, R.6
-
33
-
-
33744493091
-
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf
-
Miao EA, Alpuche-Aranda CM, Dors M, Clark AE, Bader MW, Miller SI, et al. Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf. Nat Immunol. 2006;7(6):569-75.
-
(2006)
Nat Immunol.
, vol.7
, Issue.6
, pp. 569-575
-
-
Miao, E.A.1
Alpuche-Aranda, C.M.2
Dors, M.3
Clark, A.E.4
Bader, M.W.5
Miller, S.I.6
-
34
-
-
77957578665
-
Involvement of the AIM2, NLRC4, and NLRP3 inflammasomes in caspase-1 activation by Listeria monocytogenes
-
Wu J, Fernandes-Alnemri T, Alnemri ES. Involvement of the AIM2, NLRC4, and NLRP3 inflammasomes in caspase-1 activation by Listeria monocytogenes. J Clin Immunol. 2010;30(5):693-702.
-
(2010)
J Clin Immunol.
, vol.30
, Issue.5
, pp. 693-702
-
-
Wu, J.1
Fernandes-Alnemri, T.2
Alnemri, E.S.3
-
35
-
-
47249095738
-
Multiple Nod-like receptors activate caspase 1 during Listeria monocytogenes infection
-
Warren SE, Mao DP, Rodriguez AE, Miao EA, Aderem A. Multiple Nod-like receptors activate caspase 1 during Listeria monocytogenes infection. J Immunol. 2008;180(11):7558-64.
-
(2008)
J Immunol.
, vol.180
, Issue.11
, pp. 7558-7564
-
-
Warren, S.E.1
Mao, D.P.2
Rodriguez, A.E.3
Miao, E.A.4
Aderem, A.5
-
36
-
-
77649241461
-
Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome
-
Miao EA, Mao DP, Yudkovsky N, Bonneau R, Lorang CG, Warren SE, et al. Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome. Proc Nat Acad Sci USA. 2010;107(7):3076-80.
-
(2010)
Proc Nat Acad Sci USA.
, vol.107
, Issue.7
, pp. 3076-3080
-
-
Miao, E.A.1
Mao, D.P.2
Yudkovsky, N.3
Bonneau, R.4
Lorang, C.G.5
Warren, S.E.6
-
37
-
-
33645770203
-
The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection
-
Zamboni DS, Kobayashi KS, Kohlsdorf T, Ogura Y, Long EM, Vance RE, et al. The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection. Nat Immunol. 2006;7(3):318-25.
-
(2006)
Nat Immunol.
, vol.7
, Issue.3
, pp. 318-325
-
-
Zamboni, D.S.1
Kobayashi, K.S.2
Kohlsdorf, T.3
Ogura, Y.4
Long, E.M.5
Vance, R.E.6
-
38
-
-
37549041954
-
Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome
-
Sutterwala FS, Mijares LA, Li L, Ogura Y, Kazmierczak BI, Flavell RA. Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome. J Exp Med. 2007;204(13):3235-45.
-
(2007)
J Exp Med.
, vol.204
, Issue.13
, pp. 3235-3245
-
-
Sutterwala, F.S.1
Mijares, L.A.2
Li, L.3
Ogura, Y.4
Kazmierczak, B.I.5
Flavell, R.A.6
-
39
-
-
77749270973
-
Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B activation but proceeds independently of TLR signaling and P2X7 receptor
-
Harder J, Franchi L, Munoz-Planillo R, Park JH, Reimer T, Nunez G. Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B activation but proceeds independently of TLR signaling and P2X7 receptor. J Immunol. 2009;183(9):5823-9.
-
(2009)
J Immunol.
, vol.183
, Issue.9
, pp. 5823-5829
-
-
Harder, J.1
Franchi, L.2
Munoz-Planillo, R.3
Park, J.H.4
Reimer, T.5
Nunez, G.6
-
40
-
-
76249108958
-
Listeria monocytogenes-infected human peripheral blood mononuclear cells produce IL-1beta, depending on listeriolysin O and NLRP3
-
Meixenberger K, Pache F, Eitel J, Schmeck B, Hippenstiel S, Slevogt H, et al. Listeria monocytogenes-infected human peripheral blood mononuclear cells produce IL-1beta, depending on listeriolysin O and NLRP3. J Immunol. 2010;184(2):922-30.
-
(2010)
J Immunol.
, vol.184
, Issue.2
, pp. 922-930
-
-
Meixenberger, K.1
Pache, F.2
Eitel, J.3
Schmeck, B.4
Hippenstiel, S.5
Slevogt, H.6
-
41
-
-
77955482224
-
Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome
-
Ng J, Hirota SA, Gross O, Li Y, Ulke-Lemee A, Potentier MS, et al. Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome. Gastroenterology. 2010;139(2):542-52, 552. e1-3.
-
(2010)
Gastroenterology.
, vol.139
, Issue.2
-
-
Ng, J.1
Hirota, S.A.2
Gross, O.3
Li, Y.4
Ulke-Lemee, A.5
Potentier, M.S.6
-
42
-
-
70349334298
-
A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureus-induced activation of the Nlrp3 inflammasome
-
Munoz-Planillo R, Franchi L, Miller LS, Nunez G. A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureus-induced activation of the Nlrp3 inflammasome. J Immunol. 2009;183(6):3942-8.
-
(2009)
J Immunol.
, vol.183
, Issue.6
, pp. 3942-3948
-
-
Munoz-Planillo, R.1
Franchi, L.2
Miller, L.S.3
Nunez, G.4
-
43
-
-
33748598700
-
Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival
-
Gurcel L, Abrami L, Girardin S, Tschopp J, van der Goot FG. Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival. Cell. 2006;126(6):1135-45.
-
(2006)
Cell.
, vol.126
, Issue.6
, pp. 1135-1145
-
-
Gurcel, L.1
Abrami, L.2
Girardin, S.3
Tschopp, J.4
van der Goot, F.G.5
-
44
-
-
77953562208
-
A Yersinia effector protein promotes virulence by preventing inflammasome recognition of the type III secretion system
-
Brodsky IE, Palm NW, Sadanand S, Ryndak MB, Sutterwala FS, Flavell RA, et al. A Yersinia effector protein promotes virulence by preventing inflammasome recognition of the type III secretion system. Cell Host Microbe. 2010;7(5):376-87.
-
(2010)
Cell Host Microbe.
, vol.7
, Issue.5
, pp. 376-387
-
-
Brodsky, I.E.1
Palm, N.W.2
Sadanand, S.3
Ryndak, M.B.4
Sutterwala, F.S.5
Flavell, R.A.6
-
45
-
-
77955390094
-
Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella
-
Broz P, Newton K, Lamkanfi M, Mariathasan S, Dixit VM, Monack DM. Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella. J Exp Med. 2010;207(8):1745-55.
-
(2010)
J Exp Med.
, vol.207
, Issue.8
, pp. 1745-1755
-
-
Broz, P.1
Newton, K.2
Lamkanfi, M.3
Mariathasan, S.4
Dixit, V.M.5
Monack, D.M.6
-
46
-
-
67349271142
-
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
-
Gross O, Poeck H, Bscheider M, Dostert C, Hannesschlager N, Endres S, et al. Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence. Nature. 2009;459(7245):433-6.
-
(2009)
Nature.
, vol.459
, Issue.7245
, pp. 433-436
-
-
Gross, O.1
Poeck, H.2
Bscheider, M.3
Dostert, C.4
Hannesschlager, N.5
Endres, S.6
-
47
-
-
68349157477
-
Malarial hemozoin is a Nalp3 inflammasome activating danger signal
-
Dostert C, Guarda G, Romero JF, Menu P, Gross O, Tardivel A, et al. Malarial hemozoin is a Nalp3 inflammasome activating danger signal. PLoS One. 2009;4(8):e6510.
-
(2009)
PLoS One.
, vol.4
, Issue.8
-
-
Dostert, C.1
Guarda, G.2
Romero, J.F.3
Menu, P.4
Gross, O.5
Tardivel, A.6
-
48
-
-
74049105256
-
Pure Hemozoin is inflammatory in vivo and activates the NALP3 inflammasome via release of uric acid
-
Griffith JW, Sun T, McIntosh MT, Bucala R. Pure Hemozoin is inflammatory in vivo and activates the NALP3 inflammasome via release of uric acid. J Immunol. 2009;183(8):5208-20.
-
(2009)
J Immunol.
, vol.183
, Issue.8
, pp. 5208-5220
-
-
Griffith, J.W.1
Sun, T.2
McIntosh, M.T.3
Bucala, R.4
-
49
-
-
38149035199
-
Haemozoin formation
-
Egan TJ. Haemozoin formation. Mol Biochem Parasitol. 2008;157(2):127-36.
-
(2008)
Mol Biochem Parasitol.
, vol.157
, Issue.2
, pp. 127-136
-
-
Egan, T.J.1
-
50
-
-
64049111768
-
The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA
-
Allen IC, Scull MA, Moore CB, Holl EK, McElvania-Tekippe E, Taxman DJ, et al. The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity. 2009;30(4):556-65.
-
(2009)
Immunity.
, vol.30
, Issue.4
, pp. 556-565
-
-
Allen, I.C.1
Scull, M.A.2
Moore, C.B.3
Holl, E.K.4
McElvania-Tekippe, E.5
Taxman, D.J.6
-
51
-
-
33846014297
-
Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA
-
Kanneganti TD, Body-Malapel M, Amer A, Park JH, Whitfield J, Franchi L, et al. Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA. J Biol Chem. 2006;281(48):36560-8.
-
(2006)
J Biol Chem.
, vol.281
, Issue.48
, pp. 36560-36568
-
-
Kanneganti, T.D.1
Body-Malapel, M.2
Amer, A.3
Park, J.H.4
Whitfield, J.5
Franchi, L.6
-
52
-
-
77951295418
-
Influenza virus activates inflammasomes via its intracellular M2 ion channel
-
Ichinohe T, Pang IK, Iwasaki A. Influenza virus activates inflammasomes via its intracellular M2 ion channel. Nat Immunol. 2010;11(5):404-10.
-
(2010)
Nat Immunol.
, vol.11
, Issue.5
, pp. 404-410
-
-
Ichinohe, T.1
Pang, I.K.2
Iwasaki, A.3
-
54
-
-
31744441475
-
Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
-
Boyden ED, Dietrich WF. Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin. Nat Genet. 2006;38(2):240-4.
-
(2006)
Nat Genet.
, vol.38
, Issue.2
, pp. 240-244
-
-
Boyden, E.D.1
Dietrich, W.F.2
-
55
-
-
2442701424
-
Anthrax lethal toxin rapidly activates caspase-1/ICE and induces extracellular release of interleukin (IL)-1beta and IL-18
-
Cordoba-Rodriguez R, Fang H, Lankford CS, Frucht DM. Anthrax lethal toxin rapidly activates caspase-1/ICE and induces extracellular release of interleukin (IL)-1beta and IL-18. J Biol Chem. 2004;279(20):20563-6.
-
(2004)
J Biol Chem.
, vol.279
, Issue.20
, pp. 20563-20566
-
-
Cordoba-Rodriguez, R.1
Fang, H.2
Lankford, C.S.3
Frucht, D.M.4
-
56
-
-
0032755353
-
Anthrax lethal factor cleaves MKK3 in macrophages and inhibits the LPS/IFNgamma-induced release of NO and TNFalpha
-
Pellizzari R, Guidi-Rontani C, Vitale G, Mock M, Montecucco C. Anthrax lethal factor cleaves MKK3 in macrophages and inhibits the LPS/IFNgamma-induced release of NO and TNFalpha. FEBS Lett. 1999;462(1-2):199-204.
-
(1999)
FEBS Lett.
, vol.462
, Issue.1-2
, pp. 199-204
-
-
Pellizzari, R.1
Guidi-Rontani, C.2
Vitale, G.3
Mock, M.4
Montecucco, C.5
-
57
-
-
36349019887
-
Proteasomes control caspase-1 activation in anthrax lethal toxin-mediated cell killing
-
Squires RC, Muehlbauer SM, Brojatsch J. Proteasomes control caspase-1 activation in anthrax lethal toxin-mediated cell killing. J Biol Chem. 2007;282(47):34260-7.
-
(2007)
J Biol Chem.
, vol.282
, Issue.47
, pp. 34260-34267
-
-
Squires, R.C.1
Muehlbauer, S.M.2
Brojatsch, J.3
-
58
-
-
45549093755
-
A NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptide
-
Hsu LC, Ali SR, McGillivray S, Tseng PH, Mariathasan S, Humke EW, et al. A NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptide. Proc Nat Acad Sci USA. 2008;105(22):7803-8.
-
(2008)
Proc Nat Acad Sci USA.
, vol.105
, Issue.22
, pp. 7803-7808
-
-
Hsu, L.C.1
Ali, S.R.2
McGillivray, S.3
Tseng, P.H.4
Mariathasan, S.5
Humke, E.W.6
-
59
-
-
77951263260
-
The AIM2 inflammasome is critical for innate immunity to Francisella tularensis
-
Fernandes-Alnemri T, Yu JW, Juliana C, Solorzano L, Kang S, Wu J, et al. The AIM2 inflammasome is critical for innate immunity to Francisella tularensis. Nat Immunol. 2010;11(5):385-93.
-
(2010)
Nat Immunol.
, vol.11
, Issue.5
, pp. 385-393
-
-
Fernandes-Alnemri, T.1
Yu, J.W.2
Juliana, C.3
Solorzano, L.4
Kang, S.5
Wu, J.6
-
60
-
-
77951269392
-
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
-
Rathinam VA, Jiang Z, Waggoner SN, Sharma S, Cole LE, Waggoner L, et al. The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses. Nat Immunol. 2010;11(5):395-402.
-
(2010)
Nat Immunol.
, vol.11
, Issue.5
, pp. 395-402
-
-
Rathinam, V.A.1
Jiang, Z.2
Waggoner, S.N.3
Sharma, S.4
Cole, L.E.5
Waggoner, L.6
-
61
-
-
77955294800
-
Listeria monocytogenes triggers AIM2-mediated pyroptosis upon infrequent bacteriolysis in the macrophage cytosol
-
Sauer JD, Witte CE, Zemansky J, Hanson B, Lauer P, Portnoy DA. Listeria monocytogenes triggers AIM2-mediated pyroptosis upon infrequent bacteriolysis in the macrophage cytosol. Cell Host Microbe. 2010;7(5):412-9.
-
(2010)
Cell Host Microbe.
, vol.7
, Issue.5
, pp. 412-419
-
-
Sauer, J.D.1
Witte, C.E.2
Zemansky, J.3
Hanson, B.4
Lauer, P.5
Portnoy, D.A.6
-
62
-
-
77955501642
-
Cutting edge: Cytosolic bacterial DNA activates the inflammasome via Aim2
-
Warren SE, Armstrong A, Hamilton MK, Mao DP, Leaf IA, Miao EA, et al. Cutting edge: Cytosolic bacterial DNA activates the inflammasome via Aim2. J Immunol. 2010;185(2):818-21.
-
(2010)
J Immunol.
, vol.185
, Issue.2
, pp. 818-821
-
-
Warren, S.E.1
Armstrong, A.2
Hamilton, M.K.3
Mao, D.P.4
Leaf, I.A.5
Miao, E.A.6
-
63
-
-
60749136484
-
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
-
Burckstummer T, Baumann C, Bluml S, Dixit E, Durnberger G, Jahn H, et al. An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome. Nat Immunol. 2009;10(3):266-72.
-
(2009)
Nat Immunol.
, vol.10
, Issue.3
, pp. 266-272
-
-
Burckstummer, T.1
Baumann, C.2
Bluml, S.3
Dixit, E.4
Durnberger, G.5
Jahn, H.6
-
64
-
-
63649145255
-
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
-
Fernandes-Alnemri T, Yu JW, Datta P, Wu J, Alnemri ES. AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature. 2009;458(7237):509-13.
-
(2009)
Nature.
, vol.458
, Issue.7237
, pp. 509-513
-
-
Fernandes-Alnemri, T.1
Yu, J.W.2
Datta, P.3
Wu, J.4
Alnemri, E.S.5
-
65
-
-
63649133278
-
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
-
Hornung V, Ablasser A, Charrel-Dennis M, Bauernfeind F, Horvath G, Caffrey DR, et al. AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature. 2009;458(7237):514-8.
-
(2009)
Nature.
, vol.458
, Issue.7237
, pp. 514-518
-
-
Hornung, V.1
Ablasser, A.2
Charrel-Dennis, M.3
Bauernfeind, F.4
Horvath, G.5
Caffrey, D.R.6
-
66
-
-
79957576718
-
NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis
-
Elinav E, Strowig T, Kau AL, Henao-Mejia J, Thaiss CA, Booth CJ, et al. NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Cell. 2011;145(5):745-57.
-
(2011)
Cell.
, vol.145
, Issue.5
, pp. 745-757
-
-
Elinav, E.1
Strowig, T.2
Kau, A.L.3
Henao-Mejia, J.4
Thaiss, C.A.5
Booth, C.J.6
-
67
-
-
39749084641
-
Active caspase-1 is a regulator of unconventional protein secretion
-
Keller M, Ruegg A, Werner S, Beer HD. Active caspase-1 is a regulator of unconventional protein secretion. Cell. 2008;132(5):818-31.
-
(2008)
Cell.
, vol.132
, Issue.5
, pp. 818-831
-
-
Keller, M.1
Ruegg, A.2
Werner, S.3
Beer, H.D.4
-
68
-
-
33749576792
-
Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages
-
Fink SL, Cookson BT. Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages. Cell Microbiol. 2006;8(11):1812-25.
-
(2006)
Cell Microbiol.
, vol.8
, Issue.11
, pp. 1812-1825
-
-
Fink, S.L.1
Cookson, B.T.2
-
69
-
-
80052562510
-
Asc Modulates the Function of NLRC4 in Response to Infection of Macrophages by Legionella pneumophila
-
Case CL, Roy CR. Asc Modulates the Function of NLRC4 in Response to Infection of Macrophages by Legionella pneumophila. MBio. 2011;2(4):e00117-11.
-
(2011)
MBio.
, vol.2
, Issue.4
-
-
Case, C.L.1
Roy, C.R.2
-
70
-
-
78650210802
-
Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing
-
Broz P, von Moltke J, Jones JW, Vance RE, Monack DM. Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing. Cell Host Microbe. 2010;8(6):471-83.
-
(2010)
Cell Host Microbe.
, vol.8
, Issue.6
, pp. 471-483
-
-
Broz, P.1
von Moltke, J.2
Jones, J.W.3
Vance, R.E.4
Monack, D.M.5
-
71
-
-
34548434775
-
Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages
-
Suzuki T, Franchi L, Toma C, Ashida H, Ogawa M, Yoshikawa Y, et al. Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages. PLoS Pathog. 2007;3(8):e111.
-
(2007)
PLoS Pathog.
, vol.3
, Issue.8
-
-
Suzuki, T.1
Franchi, L.2
Toma, C.3
Ashida, H.4
Ogawa, M.5
Yoshikawa, Y.6
-
72
-
-
30844432876
-
Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization
-
Yu JW, Wu J, Zhang Z, Datta P, Ibrahimi I, Taniguchi S, et al. Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization. Cell Death Differ. 2006;13(2):236-49.
-
(2006)
Cell Death Differ.
, vol.13
, Issue.2
, pp. 236-249
-
-
Yu, J.W.1
Wu, J.2
Zhang, Z.3
Datta, P.4
Ibrahimi, I.5
Taniguchi, S.6
|