Substrate inhibition and allosteric regulation by heparan sulfate of Trypanosoma brucei cathepsin L

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1824, Issue 3, 2012, Pages 493-501

  Costa, Tatiana F R ^a   Reis, Flavia C G Dos ^a   Lima, Ana Paula C A ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Allosteric; Brucipain; Heparan; Inhibition; Rhodesain; Trypanosoma brucei

Indexed keywords

BENZYLOXYCARBONYLPHENYLALANYLARGININE 7 AMINO 4 METHYLCOUMARIN; BENZYLOXYCARBONYLVALYLLEUCYLARGININE 7 AMINO 4 METHYLCOUMARIN; BRUCIPAIN; CATHEPSIN L; CYSTEINE PROTEINASE; HEPARAN SULFATE; UNCLASSIFIED DRUG;

AFRICAN TRYPANOSOMIASIS; ALLOSTERISM; ARTICLE; CONFORMATIONAL TRANSITION; ENZYME INHIBITION; ENZYME SUBSTRATE; PRIORITY JOURNAL; TRYPANOSOMA BRUCEI;

ALLOSTERIC REGULATION; ANIMALS; CATHEPSIN L; CELL CULTURE TECHNIQUES; COUMARINS; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; ESCHERICHIA COLI; FIBRINOGEN; HEPARITIN SULFATE; HUMANS; KINETICS; LIFE CYCLE STAGES; PROTEOLYSIS; PROTOZOAN PROTEINS; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; TEMPERATURE; TRYPANOSOMA BRUCEI BRUCEI;

ANIMALIA; MAMMALIA; PROTOZOA; TRYPANOSOMA BRUCEI;

EID: 84856286982     PISSN: 15709639     EISSN: 18781454     Source Type: Journal    
DOI: 10.1016/j.bbapap.2011.12.006     Document Type: Article

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