Defining an allosteric circuit in the cysteine protease domain of Clostridium difficile toxins

Nature Structural and Molecular Biology

Volumn 18, Issue 3, 2011, Pages 364-371

  Shen, Aimee ^a   Lupardus, Patrick J ^a,b,d   Gersch, Malte M ^a   Puri, Aaron W ^c   Albrow, Victoria E ^a,d   Garcia, K Christopher ^a,b   Bogyo, Matthew ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^d GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLOSTRIDIUM DIFFICILE TOXIN A; CLOSTRIDIUM DIFFICILE TOXIN B; CYSTEINE PROTEINASE; PHYTIC ACID; TRYPTOPHAN;

ALLOSTERISM; ARTICLE; BACTERIAL VIRULENCE; BINDING SITE; CLOSTRIDIUM DIFFICILE; ENZYME STRUCTURE; FLUORESCENCE; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN DOMAIN;

ALLOSTERIC REGULATION; BACTERIAL PROTEINS; BACTERIAL TOXINS; CLOSTRIDIUM DIFFICILE; CRYSTALLOGRAPHY, X-RAY; CYSTEINE PROTEASES; DISULFIDES; MODELS, MOLECULAR; PHYTIC ACID; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; TRYPTOPHAN;

BACTERIA (MICROORGANISMS); CLOSTRIDIUM DIFFICILE; EUKARYOTA;

EID: 79952360670     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb.1990     Document Type: Article

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