Cysteine protease isoforms from Trypanosoma cruzi, cruzipain 2 and cruzain, present different substrate preference and susceptibility to inhibitors

Molecular and Biochemical Parasitology

Volumn 114, Issue 1, 2001, Pages 41-52

  Lima, Ana Paula C A ^a   Dos Reis, Flavia C G ^a   Serveau, Carole ^b   Lalmanach, Gilles ^b   Juliano, Luis ^c   Ménard, Robert ^d   Vernet, Thierry ^d   Thomas, David Y ^d   Storer, Andrew C ^d   Scharfstein, Julio ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b INSERM   (France)

^c FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^d NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

Cruzipain; Cysteine protease; Expression; Isoforms; Specificity; Trypanosoma cruzi

Indexed keywords

CRUZIPAIN; CYSTEINE PROTEINASE; ISOPROTEIN;

ADAPTATION; ANTIBIOTIC RESISTANCE; ARTICLE; CELL DIFFERENTIATION; CELL GROWTH; CHAGAS DISEASE; CONTROLLED STUDY; ENZYME SPECIFICITY; ENZYME STABILITY; GENE SEQUENCE; GENETIC CODE; GENETIC POLYMORPHISM; MAMMAL; MULTIGENE FAMILY; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE SURVIVAL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEINASE INHIBITION; TRYPANOSOMA CRUZI;

TRYPANOSOMA CRUZI;

EID: 0035946353     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(01)00236-5     Document Type: Article

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