메뉴 건너뛰기




Volumn 13, Issue 1, 2012, Pages 142-172

Protein kinases and transcription factors activation in response to UV-radiation of skin: Implications for carcinogenesis

Author keywords

AP 1; ATM; ERK1 2; JNK; MAPK; NF B; NRF2 transcription factors; P38; Skin cancer; Skin photoaging; SKR kinases; Ultraviolet radiation

Indexed keywords

ATM PROTEIN; EPIGALLOCATECHIN GALLATE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAGNOLOL; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; OLIGODEOXYNUCLEOTIDE; PARTHENOLIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PROANTHOCYANIDIN; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NRF2; PROTEIN KINASE; TRANSCRIPTION FACTOR;

EID: 84856247542     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms13010142     Document Type: Article
Times cited : (140)

References (172)
  • 1
    • 0020565091 scopus 로고
    • Photocarcinogenesis, skin cancer, and aging
    • Epstein, J.H. Photocarcinogenesis, skin cancer, and aging. J. Am. Acad. Dermatol. 1983, 9, 487-502.
    • (1983) J. Am. Acad. Dermatol. , vol.9 , pp. 487-502
    • Epstein, J.H.1
  • 2
    • 0035472223 scopus 로고    scopus 로고
    • UV-induced DNA damage, repair, mutations and oncogenic pathways in skin cancer
    • de Gruijl, F.R.; van Kranen, H.J.; Mullenders, L.H. UV-induced DNA damage, repair, mutations and oncogenic pathways in skin cancer. J. Photochem. Photobiol. 2001, B63, 19-27.
    • (2001) J. Photochem. Photobiol. , vol.B , pp. 19-27
    • de Gruijl, F.R.1    van Kranen, H.J.2    Mullenders, L.H.3
  • 4
    • 21744434825 scopus 로고    scopus 로고
    • UV-induced skin cancer: Similarities-variations
    • Boukamp, P. UV-induced skin cancer: Similarities-variations. J. Dtsch. Dermatol. Ges. 2005, 3, 493-503.
    • (2005) J. Dtsch. Dermatol. Ges. , vol.3 , pp. 493-503
    • Boukamp, P.1
  • 5
    • 0016299016 scopus 로고
    • The wavelengths in sunlight effective in producing skin cancer: A theoretical analysis
    • Setlow, R.B. The wavelengths in sunlight effective in producing skin cancer: A theoretical analysis. Proc. Natl. Acad. Sci. USA 1974, 71, 3363-3366.
    • (1974) Proc. Natl. Acad. Sci. USA , vol.71 , pp. 3363-3366
    • Setlow, R.B.1
  • 6
    • 24644452957 scopus 로고    scopus 로고
    • UV doses worldwide
    • Godar, D.E. UV doses worldwide. Photochem. Photobiol. 2005, 81, 736-749.
    • (2005) Photochem. Photobiol. , vol.81 , pp. 736-749
    • Godar, D.E.1
  • 7
    • 0031426132 scopus 로고    scopus 로고
    • Wavelength dependence of oxidative DNA damage induced by UV and visible light
    • Kielbassa, C.; Roza, L.; Epe, B. Wavelength dependence of oxidative DNA damage induced by UV and visible light. Carcinogenesis 1997, 18, 811-816.
    • (1997) Carcinogenesis , vol.18 , pp. 811-816
    • Kielbassa, C.1    Roza, L.2    Epe, B.3
  • 8
    • 0035472817 scopus 로고    scopus 로고
    • Direct and indirect effects of UV radiation on DNA and its components
    • Ravanat, J.L.; Douki, T.; Cadet, J. Direct and indirect effects of UV radiation on DNA and its components. J. Photochem. Photobiol. 2001, B63, 88-102.
    • (2001) J. Photochem. Photobiol. , vol.B63 , pp. 88-102
    • Ravanat, J.L.1    Douki, T.2    Cadet, J.3
  • 9
    • 34249808829 scopus 로고    scopus 로고
    • Ultraviolet B regulation of transcription factor families: Roles of nuclear factor-kappa B (NF-κB) and activator protein-1 (AP-1) in UVB-induced skin carcinogenesis
    • Cooper, S.J.; Bowden, G.T. Ultraviolet B regulation of transcription factor families: Roles of nuclear factor-kappa B (NF-κB) and activator protein-1 (AP-1) in UVB-induced skin carcinogenesis. Curr. Cancer Drug Targets 2007, 7, 325-334.
    • (2007) Curr. Cancer Drug Targets , vol.7 , pp. 325-334
    • Cooper, S.J.1    Bowden, G.T.2
  • 11
    • 0033923503 scopus 로고    scopus 로고
    • Photocarcinogenesis: UVA vs. UVB
    • de Gruijl, F.R. Photocarcinogenesis: UVA vs. UVB. Methods Enzymol. 2000, 319, 359-366.
    • (2000) Methods Enzymol , vol.319 , pp. 359-366
    • de Gruijl, F.R.1
  • 12
    • 84989741832 scopus 로고
    • UVA effects on mammalian skin and cells
    • Gange, W.R.; Rosen, C.F. UVA effects on mammalian skin and cells. Photochem. Photobiol. 1986, 43, 701-705.
    • (1986) Photochem. Photobiol. , vol.43 , pp. 701-705
    • Gange, W.R.1    Rosen, C.F.2
  • 13
    • 0030975810 scopus 로고    scopus 로고
    • Induction of cancer, acidic keratosis, and specific p53 mutations by UVB light in human skin maintained in severe combined immunodeficient mice
    • Nomura, T.; Nakajima, M.; Hongyo, T.; Taniguchi, E.; Fukuda, K.; Li, L.; Kurooka, M.; Sutoh, K.; Hande, P.; Kawaguchi, T.; et al. Induction of cancer, acidic keratosis, and specific p53 mutations by UVB light in human skin maintained in severe combined immunodeficient mice. Cancer Res. 1997, 57, 2081-2084.
    • (1997) Cancer Res , vol.57 , pp. 2081-2084
    • Nomura, T.1    Nakajima, M.2    Hongyo, T.3    Taniguchi, E.4    Fukuda, K.5    Li, L.6    Kurooka, M.7    Sutoh, K.8    Hande, P.9    Kawaguchi, T.10
  • 14
    • 0036159406 scopus 로고    scopus 로고
    • Early signaling events induced by 280-nm UV irradiation
    • Kabuyama, Y.; Homma, M.K.; Kurosaki, T.; Homma, Y. Early signaling events induced by 280-nm UV irradiation. Eur. J. Biochem. 2002, 269, 664-670.
    • (2002) Eur. J. Biochem. , vol.269 , pp. 664-670
    • Kabuyama, Y.1    Homma, M.K.2    Kurosaki, T.3    Homma, Y.4
  • 15
    • 38349010520 scopus 로고    scopus 로고
    • Mechanisms of mutation formation with long-wave ultraviolet light (UVA)
    • Runger, T.M.; Kappes, U.P. Mechanisms of mutation formation with long-wave ultraviolet light (UVA). Photodermatol. Photoimmunol. Photomed. 2008, 24, 2-10.
    • (2008) Photodermatol. Photoimmunol. Photomed. , vol.24 , pp. 2-10
    • Runger, T.M.1    Kappes, U.P.2
  • 18
    • 0030088026 scopus 로고    scopus 로고
    • Activation of mammalian gene expression by the UV component of sunlight-from models to reality
    • Tyrrell, R.M. Activation of mammalian gene expression by the UV component of sunlight-from models to reality. Bioessays 1996, 18, 139-148.
    • (1996) Bioessays , vol.18 , pp. 139-148
    • Tyrrell, R.M.1
  • 20
    • 0036175318 scopus 로고    scopus 로고
    • Induction of EGFR-dependent and EGFR-independent signaling pathways by ultraviolet A irradiation
    • Zhang, Y.; Dong, Z.; Bode, A.M.; Ma, W.Y.; Chen, N.; Dong, Z. Induction of EGFR-dependent and EGFR-independent signaling pathways by ultraviolet A irradiation. DNA Cell Biol. 2001, 20, 769-779.
    • (2001) DNA Cell Biol , vol.20 , pp. 769-779
    • Zhang, Y.1    Dong, Z.2    Bode, A.M.3    Ma, W.Y.4    Chen, N.5    Dong, Z.6
  • 21
    • 0029860936 scopus 로고    scopus 로고
    • Ultraviolet light and osmotic stress: Activation of the JNK cascade through multiple growth factor and cytokine receptors
    • Rosette, C.; Karin, M. Ultraviolet light and osmotic stress: Activation of the JNK cascade through multiple growth factor and cytokine receptors. Science 1996, 274, 1194-1197.
    • (1996) Science , vol.274 , pp. 1194-1197
    • Rosette, C.1    Karin, M.2
  • 22
    • 0027049804 scopus 로고
    • The mammalian ultraviolet response is triggered by activation of Src tyrosine kinases
    • Devary, Y.; Gottlieb, R.A.; Smeal, T.; Karin, M. The mammalian ultraviolet response is triggered by activation of Src tyrosine kinases. Cell 1992, 71, 1081-1091.
    • (1992) Cell , vol.71 , pp. 1081-1091
    • Devary, Y.1    Gottlieb, R.A.2    Smeal, T.3    Karin, M.4
  • 23
    • 0029055812 scopus 로고
    • The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signalling pathway
    • Coso, O.A.; Chiariello, M.; Yu, J.C.; Teramoto, H.; Crespo, P.; Xu, N.; Miki, T.; Gutkind, J.S. The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signalling pathway. Cell 1995, 81, 1137-1146.
    • (1995) Cell , vol.81 , pp. 1137-1146
    • Coso, O.A.1    Chiariello, M.2    Yu, J.C.3    Teramoto, H.4    Crespo, P.5    Xu, N.6    Miki, T.7    Gutkind, J.S.8
  • 24
    • 0032415670 scopus 로고    scopus 로고
    • Wavelength specific activation of PI-3kinase by UVB irradiation
    • Kabuyama, Y.; Hamaya, M.; Homma, Y. Wavelength specific activation of PI-3kinase by UVB irradiation. FEBS Lett. 1998, 441, 297-301.
    • (1998) FEBS Lett , vol.441 , pp. 297-301
    • Kabuyama, Y.1    Hamaya, M.2    Homma, Y.3
  • 25
    • 17844394391 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase activation in UV induced signal transduction
    • Bode, A.M.; Dong, Z. Mitogen-activated protein kinase activation in UV induced signal transduction. Sci. STKE 2003, 2003, RE2.
    • (2003) Sci. STKE , vol.2003
    • Bode, A.M.1    Dong, Z.2
  • 26
    • 0036479241 scopus 로고    scopus 로고
    • Requirement of ATM in UVA-induced signaling and apoptosis
    • Zhang, Y.; Ma, W.Y.; Kaji, A.; Bode, A.M.; Dong, Z. Requirement of ATM in UVA-induced signaling and apoptosis. J. Biol. Chem. 2002, 277, 3124-3131.
    • (2002) J. Biol. Chem. , vol.277 , pp. 3124-3131
    • Zhang, Y.1    Ma, W.Y.2    Kaji, A.3    Bode, A.M.4    Dong, Z.5
  • 27
    • 0035805618 scopus 로고    scopus 로고
    • UVA induces Ser381 phosphorylation of p90RSK/MAPKAP-K1 via ERK and JNK pathways
    • Zhang, Y.; Zhong, S.; Dong, Z.; Chen, N.; Bode, A.M.; Ma, W.; Dong, Z. UVA induces Ser381 phosphorylation of p90RSK/MAPKAP-K1 via ERK and JNK pathways. J. Biol. Chem. 2001, 276, 14572-14580.
    • (2001) J. Biol. Chem. , vol.276 , pp. 14572-14580
    • Zhang, Y.1    Zhong, S.2    Dong, Z.3    Chen, N.4    Bode, A.M.5    Ma, W.6    Dong, Z.7
  • 28
    • 0036585055 scopus 로고    scopus 로고
    • Antiapoptotic effects induced by different wavelengths of ultraviolet light
    • Ibuki, Y.; Goto, R. Antiapoptotic effects induced by different wavelengths of ultraviolet light. Photochem. Photobiol. 2002, 75, 495-502.
    • (2002) Photochem. Photobiol. , vol.75 , pp. 495-502
    • Ibuki, Y.1    Goto, R.2
  • 30
    • 0028568217 scopus 로고
    • Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK
    • Minden, A.; Lin, A.; McMahon, M.; Lange, C.C.; Derijard, B.; Davis, R.J.; Johnson, L.; Karin, M. Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK. Science 1994, 266, 1719-1723.
    • (1994) Science , vol.266 , pp. 1719-1723
    • Minden, A.1    Lin, A.2    McMahon, M.3    Lange, C.C.4    Derijard, B.5    Davis, R.J.6    Johnson, L.7    Karin, M.8
  • 32
    • 2942530310 scopus 로고    scopus 로고
    • ERK and p38 MAPK activated protein kinases: A family of protein kinases with diverse biological functions
    • Roux, P.P.; Blenis, J. ERK and p38 MAPK activated protein kinases: A family of protein kinases with diverse biological functions. Microbiol. Mol. Biol. Rev. 2004, 68, 320-344.
    • (2004) Microbiol. Mol. Biol. Rev. , vol.68 , pp. 320-344
    • Roux, P.P.1    Blenis, J.2
  • 33
    • 80052417453 scopus 로고    scopus 로고
    • UVB and UVC Induce Differential Response Signaling Pathways Converged on the eIF2α phosphorylation
    • Zhong, J.L.; Yang, L.; Lü, F.; Xiao, H.; Xu, R.; Wang, L.; Zhu, F.; Zhang, Y. UVA, UVB and UVC Induce Differential Response Signaling Pathways Converged on the eIF2α phosphorylation. Photochem. Photobiol. 2011, 87, 1092-1104.
    • (2011) Photochem. Photobiol. , vol.87 , pp. 1092-1104
    • Zhong, J.L.1    Yang, L.2    Lü, F.3    Xiao, H.4    Xu, R.5    Wang, L.6    Zhu, F.7    Zhang, Y.U.V.A.8
  • 34
    • 0035181315 scopus 로고    scopus 로고
    • Differential phosphorylation of mitogen-activated protein kinase families by epidermal growth factor and ultraviolet B irradiation in SV40-transformed human keratinocytes
    • Nakamura, S.; Takahashi, H.; Kinouchi, M.; Manabe, A.; Ishida-Yamamoto, A.; Hashimoto, Y.; Iizuka, H. Differential phosphorylation of mitogen-activated protein kinase families by epidermal growth factor and ultraviolet B irradiation in SV40-transformed human keratinocytes. J. Dermatol. Sci. 2001, 25, 139-149.
    • (2001) J. Dermatol. Sci. , vol.25 , pp. 139-149
    • Nakamura, S.1    Takahashi, H.2    Kinouchi, M.3    Manabe, A.4    Ishida-Yamamoto, A.5    Hashimoto, Y.6    Iizuka, H.7
  • 35
    • 33846076220 scopus 로고    scopus 로고
    • The anti-apoptotic and anti-oxidant effect of eriodictyol on UV-induced apoptosis in keratinocytes
    • Lee, E.R.; Kim, J.H.; Kang, Y.J.; Cho, S.G. The anti-apoptotic and anti-oxidant effect of eriodictyol on UV-induced apoptosis in keratinocytes. Biol. Pharm. Bull. 2007, 30, 32-37.
    • (2007) Biol. Pharm. Bull. , vol.30 , pp. 32-37
    • Lee, E.R.1    Kim, J.H.2    Kang, Y.J.3    Cho, S.G.4
  • 36
    • 67749093100 scopus 로고    scopus 로고
    • Ultraviolet irradiation-induces epidermal growth factor receptor (EGFR) nuclear translocation in human keratinocytes
    • Xu, Y.; Shao, Y.; Zhou, J.; Voorhees, J.J.; Fisher, G.J. Ultraviolet irradiation-induces epidermal growth factor receptor (EGFR) nuclear translocation in human keratinocytes. J. Cell. Biochem. 2009, 107, 873-880.
    • (2009) J. Cell. Biochem. , vol.107 , pp. 873-880
    • Xu, Y.1    Shao, Y.2    Zhou, J.3    Voorhees, J.J.4    Fisher, G.J.5
  • 37
    • 84925373741 scopus 로고
    • Epidermal growth factor induced tyrosine phosphorylation of nuclear proteins associated with translocation of epidermal growth factor receptor into the nucleus
    • Holt, S.; Alexander, P.; Inman, C.; Davies, D. Epidermal growth factor induced tyrosine phosphorylation of nuclear proteins associated with translocation of epidermal growth factor receptor into the nucleus. Biochem. Pharmacol. 1995, 133, 211-222.
    • (1995) Biochem. Pharmacol. , vol.133 , pp. 211-222
    • Holt, S.1    Alexander, P.2    Inman, C.3    Davies, D.4
  • 38
    • 0034855942 scopus 로고    scopus 로고
    • Nuclear localization of EGF receptor and its potential new role as a transcription factor
    • Lin, S.; Makino, K.; Xia, W.; Matin, A.; Wen, Y.; Kwong, K.; Bourguignon, L.; Hung, M. Nuclear localization of EGF receptor and its potential new role as a transcription factor. Nat. Cell. Biol. 2001, 3, 802-808.
    • (2001) Nat. Cell. Biol. , vol.3 , pp. 802-808
    • Lin, S.1    Makino, K.2    Xia, W.3    Matin, A.4    Wen, Y.5    Kwong, K.6    Bourguignon, L.7    Hung, M.8
  • 39
    • 0035066383 scopus 로고    scopus 로고
    • Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
    • Kyriakis, J.M.; Avruch, J. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol. Rev. 2001, 81, 807-869.
    • (2001) Physiol. Rev. , vol.81 , pp. 807-869
    • Kyriakis, J.M.1    Avruch, J.2
  • 40
    • 0028935270 scopus 로고
    • Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine
    • Raingeaud, J.; Gupta, S.; Rogers, J.S.; Dickens, M.; Han, J.; Ulevitch, R.J.; Davis, R.J. Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J. Biol. Chem. 1995, 270, 7420-7426.
    • (1995) J. Biol. Chem. , vol.270 , pp. 7420-7426
    • Raingeaud, J.1    Gupta, S.2    Rogers, J.S.3    Dickens, M.4    Han, J.5    Ulevitch, R.J.6    Davis, R.J.7
  • 41
    • 0033964592 scopus 로고    scopus 로고
    • Inhibition of atypical PKC blocks ultraviolet-induced AP-1 activation by specifically inhibiting ERKs activation
    • Huang, C.; Li, J.; Chen, N.; Ma, W.; Bowden, G.T.; Dong, Z. Inhibition of atypical PKC blocks ultraviolet-induced AP-1 activation by specifically inhibiting ERKs activation. Mol. Carcinog. 2000, 27, 65-75.
    • (2000) Mol. Carcinog. , vol.27 , pp. 65-75
    • Huang, C.1    Li, J.2    Chen, N.3    Ma, W.4    Bowden, G.T.5    Dong, Z.6
  • 42
    • 0032485026 scopus 로고    scopus 로고
    • Solar ultraviolet light activates extracellular signal-regulated kinases and the ternary complex factor in human normal keratinocytes
    • Englaro, W.; Derijard, B.; Ortonne, J.P.; Ballotti, R. Solar ultraviolet light activates extracellular signal-regulated kinases and the ternary complex factor in human normal keratinocytes. Oncogene 1998, 16, 661-664.
    • (1998) Oncogene , vol.16 , pp. 661-664
    • Englaro, W.1    Derijard, B.2    Ortonne, J.P.3    Ballotti, R.4
  • 43
    • 0035024784 scopus 로고    scopus 로고
    • UV-A-induced AP-1 activation requires the Raf/ERK pathway in human NCTC 2544 keratinocytes
    • Djavaheri-Mergny, M.; Dubertret, L. UV-A-induced AP-1 activation requires the Raf/ERK pathway in human NCTC 2544 keratinocytes. Exp. Dermatol. 2001, 10, 204-210.
    • (2001) Exp. Dermatol. , vol.10 , pp. 204-210
    • Djavaheri-Mergny, M.1    Dubertret, L.2
  • 44
    • 0035515358 scopus 로고    scopus 로고
    • Rays and arrays: The transcriptional program in the response of human epidermal keratinocytes to UVB illumination
    • Li, D.; Turi, T.G.; Schuck, A.; Freedberg, I.M.; Khitrov, G.; Blumenberg, M. Rays and arrays: The transcriptional program in the response of human epidermal keratinocytes to UVB illumination. FASEB J. 2001, 15, 2533-2535.
    • (2001) FASEB J , vol.15 , pp. 2533-2535
    • Li, D.1    Turi, T.G.2    Schuck, A.3    Freedberg, I.M.4    Khitrov, G.5    Blumenberg, M.6
  • 45
    • 0035088738 scopus 로고    scopus 로고
    • Possible involvement of ERK 1/2 in UVA-induced melanogenesis in cultured normal human epidermal melanocytes
    • Yanase, H.; Ando, H.; Horikawa, M.; Watanabe, M.; Mori, T.; Matsuda, N. Possible involvement of ERK 1/2 in UVA-induced melanogenesis in cultured normal human epidermal melanocytes. Pigment Cell Res. 2001, 14, 103-109.
    • (2001) Pigment Cell Res , vol.14 , pp. 103-109
    • Yanase, H.1    Ando, H.2    Horikawa, M.3    Watanabe, M.4    Mori, T.5    Matsuda, N.6
  • 46
    • 0027143725 scopus 로고
    • Protein serine/threonine phosphatases: Structure, regulation, and functions in cell growth
    • Mumby, M.C.; Walter, G. Protein serine/threonine phosphatases: Structure, regulation, and functions in cell growth. Physiol. Rev. 1993, 73, 673-699.
    • (1993) Physiol. Rev. , vol.73 , pp. 673-699
    • Mumby, M.C.1    Walter, G.2
  • 47
    • 79959432364 scopus 로고    scopus 로고
    • Cytoprotective Effect of Eriodictyol in UV-irradiated Keratinocytes via Phosphatase-dependent Modulation of both the p38 MAPK and Akt Signaling Pathways
    • Lee, E.R.; Kim, J.H.; Choi, H.Y.; Jeon, K.; Cho, S.G. Cytoprotective Effect of Eriodictyol in UV-irradiated Keratinocytes via Phosphatase-dependent Modulation of both the p38 MAPK and Akt Signaling Pathways. Cell. Physiol. Biochem. 2011, 27, 513-524.
    • (2011) Cell. Physiol. Biochem. , vol.27 , pp. 513-524
    • Lee, E.R.1    Kim, J.H.2    Choi, H.Y.3    Jeon, K.4    Cho, S.G.5
  • 48
    • 77950587919 scopus 로고    scopus 로고
    • Expression of a homeostatic regulator, Wip1 (wild-type p53-induced phosphatase), is temporally induced by c-Jun and p53 in response to UV irradiation
    • Song, J.Y.; Han, H.S.; Sabapathy, K.; Lee, B.M.; Yu, E.; Choi, J. Expression of a homeostatic regulator, Wip1 (wild-type p53-induced phosphatase), is temporally induced by c-Jun and p53 in response to UV irradiation. J. Biol. Chem. 2010, 285, 9067-9076
    • (2010) J. Biol. Chem. , vol.285 , pp. 9067-9076
    • Song, J.Y.1    Han, H.S.2    Sabapathy, K.3    Lee, B.M.4    Yu, E.5    Choi, J.6
  • 49
    • 0032554611 scopus 로고    scopus 로고
    • Specific and reversible inactivation of protein tyrosine phosphatases by hydrogen peroxide: Evidence for a sulfenic acid intermediate and implications for redox regulation
    • Denu, J.; Tanner, K. Specific and reversible inactivation of protein tyrosine phosphatases by hydrogen peroxide: Evidence for a sulfenic acid intermediate and implications for redox regulation. Biochemistry 1998, 37, 5633-5642.
    • (1998) Biochemistry , vol.37 , pp. 5633-5642
    • Denu, J.1    Tanner, K.2
  • 50
    • 0029790979 scopus 로고    scopus 로고
    • Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants or alkylating agents
    • Knebel, A.; Rahmsdorf, H.; Ullrich, A.; Herrlich, P. Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants or alkylating agents. EMBO. J. 1996, 15, 5314-5325.
    • (1996) EMBO. J. , vol.15 , pp. 5314-5325
    • Knebel, A.1    Rahmsdorf, H.2    Ullrich, A.3    Herrlich, P.4
  • 51
    • 33748743056 scopus 로고    scopus 로고
    • Oxidative inhibition of receptor-type protein-tyrosine phosphatase kappa by ultraviolet irradiation activates epidermal growth factor receptor in human keratinocytes
    • Xu, Y.; Shao, Y.; Voorhees, J.J.; Fisher, G.J. Oxidative inhibition of receptor-type protein-tyrosine phosphatase kappa by ultraviolet irradiation activates epidermal growth factor receptor in human keratinocytes. J. Biol. Chem. 2006, 281, 27389-27397.
    • (2006) J. Biol. Chem. , vol.281 , pp. 27389-27397
    • Xu, Y.1    Shao, Y.2    Voorhees, J.J.3    Fisher, G.J.4
  • 52
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • Cantley, L.C. The phosphoinositide 3-kinase pathway. Science 2002, 296, 1655-1657.
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 53
    • 0031566693 scopus 로고    scopus 로고
    • A Bad kinase makes good
    • Franke, T.F.; Cantley, L.C. A Bad kinase makes good. Nature 1997, 390, 116-117.
    • (1997) Nature , vol.390 , pp. 116-117
    • Franke, T.F.1    Cantley, L.C.2
  • 54
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of bad couples survival signals to the cell-intrinsic death machinery
    • Datta, S.R.; Dudek, H.; Tao, X.; Masters, S.; Fu, H.; Gotoh, Y.; Greenberg, M.E. Akt phosphorylation of bad couples survival signals to the cell-intrinsic death machinery. Cell 1997, 91, 231-241.
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3    Masters, S.4    Fu, H.5    Gotoh, Y.6    Greenberg, M.E.7
  • 55
    • 0034731492 scopus 로고    scopus 로고
    • Suppression of apoptosis by UVB irradiation: Survival signaling via PI3-kinase/Akt pathway
    • Ibuki, Y.; Goto, R. Suppression of apoptosis by UVB irradiation: Survival signaling via PI3-kinase/Akt pathway. Biochem. Biophys. Res. Commun. 2000, 279, 872-878.
    • (2000) Biochem. Biophys. Res. Commun. , vol.279 , pp. 872-878
    • Ibuki, Y.1    Goto, R.2
  • 56
    • 0035289595 scopus 로고    scopus 로고
    • Ultraviolet irradiation activates PI 3-kinase/Akt survival pathway via EGF receptors in human skin in vivo
    • Wan, Y.S.; Wang, Z.Q.; Shao, Y.; Voorhees, J.J.; Fisher, G.J. Ultraviolet irradiation activates PI 3-kinase/Akt survival pathway via EGF receptors in human skin in vivo. Int. J. Oncol. 2001, 18, 461-466.
    • (2001) Int. J. Oncol. , vol.18 , pp. 461-466
    • Wan, Y.S.1    Wang, Z.Q.2    Shao, Y.3    Voorhees, J.J.4    Fisher, G.J.5
  • 57
    • 0033604521 scopus 로고    scopus 로고
    • Ribosomal S6 kinase signaling and the control of translation
    • Dufner, G.T. Ribosomal S6 kinase signaling and the control of translation. Exp. Cell Res. 1999, 253, 100-109.
    • (1999) Exp. Cell Res. , vol.253 , pp. 100-109
    • Dufner, G.T.1
  • 58
    • 0040175067 scopus 로고    scopus 로고
    • Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction
    • Frodin, M.; Gammeltoft, S. Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction. Mol. Cell Endocrinol. 1999, 151, 65-77.
    • (1999) Mol. Cell Endocrinol. , vol.151 , pp. 65-77
    • Frodin, M.1    Gammeltoft, S.2
  • 59
    • 0035877641 scopus 로고    scopus 로고
    • Signal Transduction Pathways Involved in Phosphorylation and Activation of p70S6K Following Exposure to UVA Irradiation
    • Zhang, Y.; Dong, Z.; Nomura, M.; Zhong, S.; Chen, N.; Bode, A.M.; Dong, Z. Signal Transduction Pathways Involved in Phosphorylation and Activation of p70S6K Following Exposure to UVA Irradiation. J. Biol. Chem. 2001, 276, 20913-20923.
    • (2001) J. Biol. Chem. , vol.276 , pp. 20913-20923
    • Zhang, Y.1    Dong, Z.2    Nomura, M.3    Zhong, S.4    Chen, N.5    Bode, A.M.6    Dong, Z.7
  • 60
    • 0032585649 scopus 로고    scopus 로고
    • Expression of dominant negative Erk2 inhibits AP-1 transactivation and neoplastic transformation
    • Watts, R.G.; Huang, C.; Young, M.R.; Li, J.J.; Pennie, W.D.; Colburn, N.H. Expression of dominant negative Erk2 inhibits AP-1 transactivation and neoplastic transformation. Oncogene 1998, 17, 3493-3498.
    • (1998) Oncogene , vol.17 , pp. 3493-3498
    • Watts, R.G.1    Huang, C.2    Young, M.R.3    Li, J.J.4    Pennie, W.D.5    Colburn, N.H.6
  • 61
    • 0033229933 scopus 로고    scopus 로고
    • A mediator of multiple responses to genotoxic stress
    • Rotman, G.; Shiloh, Y. ATM: A mediator of multiple responses to genotoxic stress. Oncogene 1999, 18, 6135-6144.
    • (1999) Oncogene , vol.18 , pp. 6135-6144
    • Rotman, G.1    Shiloh, Y.A.T.M.2
  • 62
    • 0034576494 scopus 로고    scopus 로고
    • The many substrates and functions of ATM
    • Kastan, M.B.; Lim, D.S. The many substrates and functions of ATM. Nat. Rev. Mol. Cell Biol. 2000, 1, 179-186.
    • (2000) Nat. Rev. Mol. Cell Biol. , vol.1 , pp. 179-186
    • Kastan, M.B.1    Lim, D.S.2
  • 64
    • 0030879563 scopus 로고    scopus 로고
    • Atm and p53 cooperate in apoptosis and suppression of tumorigenesis, but not in resistance to acute radiation toxicity
    • Westphal, C.H.; Rowan, S.; Schmaltz, C.; Elson, A.; Fisher, D.E.; Leder, P. Atm and p53 cooperate in apoptosis and suppression of tumorigenesis, but not in resistance to acute radiation toxicity. Nat. Genet. 1997, 16, 397-401.
    • (1997) Nat. Genet. , vol.16 , pp. 397-401
    • Westphal, C.H.1    Rowan, S.2    Schmaltz, C.3    Elson, A.4    Fisher, D.E.5    Leder, P.6
  • 65
    • 0035210210 scopus 로고    scopus 로고
    • ATM (ataxia telangiectasia mutated): Expanding roles in the DNA damage response and cellular homeostasis
    • Shiloh, Y. ATM (ataxia telangiectasia mutated): Expanding roles in the DNA damage response and cellular homeostasis. Biochem. Soc. Trans. 2001, 29, 661-666.
    • (2001) Biochem. Soc. Trans. , vol.29 , pp. 661-666
    • Shiloh, Y.1
  • 67
    • 0035253615 scopus 로고    scopus 로고
    • ATM and ATR: Networking cellular responses to DNA damage
    • Shiloh, Y. ATM and ATR: Networking cellular responses to DNA damage. Curr. Opin. Genet. Dev. 2001, 11, 71-77.
    • (2001) Curr. Opin. Genet. Dev. , vol.11 , pp. 71-77
    • Shiloh, Y.1
  • 68
    • 0027363407 scopus 로고
    • NF-κB activation by ultraviolet light not dependent on a nuclear signal
    • Devary, Y.; Rosette, C.; DiDonato, J.A.; Karin, M. NF-κB activation by ultraviolet light not dependent on a nuclear signal. Science 1993, 261, 1442-1445.
    • (1993) Science , vol.261 , pp. 1442-1445
    • Devary, Y.1    Rosette, C.2    Didonato, J.A.3    Karin, M.4
  • 69
    • 0034163156 scopus 로고    scopus 로고
    • UV-induced DNA damage in carcinogenesis and its repair
    • Nishigori, C. UV-induced DNA damage in carcinogenesis and its repair. J. Dermatol. Sci. 2000, 23, S41-S44.
    • (2000) J. Dermatol. Sci. , vol.23
    • Nishigori, C.1
  • 72
    • 33750466230 scopus 로고    scopus 로고
    • Introduction to NF-κB: Players, pathways, perspectives
    • Gilmore, T.D. Introduction to NF-κB: Players, pathways, perspectives. Oncogene 2006, 25, 6680-6684.
    • (2006) Oncogene , vol.25 , pp. 6680-6684
    • Gilmore, T.D.1
  • 73
    • 34548487143 scopus 로고    scopus 로고
    • Beyond IκBs: Alternative regulation of NF-κB activity
    • Neumann, M.; Naumann, M. Beyond IκBs: Alternative regulation of NF-κB activity. FASEB J. 2007, 21, 2642-2654.
    • (2007) FASEB J , vol.21 , pp. 2642-2654
    • Neumann, M.1    Naumann, M.2
  • 74
    • 4444376712 scopus 로고    scopus 로고
    • Signaling to NF-κB
    • Matthew, S.H.; Ghosh, S. Signaling to NF-κB. Genes Dev. 2004, 18, 2195-2224.
    • (2004) Genes Dev , vol.18 , pp. 2195-2224
    • Matthew, S.H.1    Ghosh, S.2
  • 75
    • 77549086995 scopus 로고    scopus 로고
    • The UV response of the skin: A review of the MAPK, NF-κB and TNFα signal transduction pathways
    • Muthusamy, V.; Piva, T.J. The UV response of the skin: A review of the MAPK, NF-κB and TNFα signal transduction pathways. Arch. Dermatol. Res. 2010, 302, 5-17.
    • (2010) Arch. Dermatol. Res. , vol.302 , pp. 5-17
    • Muthusamy, V.1    Piva, T.J.2
  • 76
    • 0024404496 scopus 로고
    • UV-induced DNA damage is an intermediate step in UV-induced expression of human immunodeficiency virus type 1, collagenase, c-fos, and metallothionein
    • Stein, B.; Rahmsdorf, H.J.; Steffen, A.; Litfin, M.; Herrlich, P. UV-induced DNA damage is an intermediate step in UV-induced expression of human immunodeficiency virus type 1, collagenase, c-fos, and metallothionein. Mol. Cell Biol. 1989, 9, 5169-5181.
    • (1989) Mol. Cell Biol. , vol.9 , pp. 5169-5181
    • Stein, B.1    Rahmsdorf, H.J.2    Steffen, A.3    Litfin, M.4    Herrlich, P.5
  • 77
    • 0032573165 scopus 로고    scopus 로고
    • Ionizing radiation and short wavelength UV activate NF-κB through two distinct mechanisms
    • Li, N.; Karin, M. Ionizing radiation and short wavelength UV activate NF-κB through two distinct mechanisms. Proc. Natl. Acad. Sci. USA 1998, 95, 13012-13017.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 13012-13017
    • Li, N.1    Karin, M.2
  • 78
    • 0242298578 scopus 로고    scopus 로고
    • CK2 is a C-terminal IκB kinase responsible for NF-kB activation during UV response
    • Kato, T., Jr.; Delhase, M.; Hoffmann, A.; Karin, M. CK2 is a C-terminal IκB kinase responsible for NF-kB activation during UV response. Mol. Cell 2003, 12, 829-839.
    • (2003) Mol. Cell. , vol.12 , pp. 829-839
    • Kato Jr., T.1    Delhase, M.2    Hoffmann, A.3    Karin, M.4
  • 79
    • 0344222192 scopus 로고    scopus 로고
    • Sequential DNA damage-independent and -dependent activation of NF-κB by UV
    • Bender, K.; Gottlicher, M.; Whiteside, S.; Rahmsdorf, H.J.; Herrlich, P. Sequential DNA damage-independent and -dependent activation of NF-κB by UV. EMBO J. 1998, 17, 5170-5181.
    • (1998) EMBO J , vol.17 , pp. 5170-5181
    • Bender, K.1    Gottlicher, M.2    Whiteside, S.3    Rahmsdorf, H.J.4    Herrlich, P.5
  • 80
    • 0028222788 scopus 로고
    • UVB light induces nuclear factor kB (NFkB) activity independently from chromosomal DNA damage in cell-free cytosolic extracts
    • Simon, M.M.; Aragane, Y.; Schwarz, A.; Luger, T.A.; Schwarz, T. UVB light induces nuclear factor kB (NFkB) activity independently from chromosomal DNA damage in cell-free cytosolic extracts. J. Invest. Dermatol. 1994, 102, 422-427.
    • (1994) J. Invest. Dermatol. , vol.102 , pp. 422-427
    • Simon, M.M.1    Aragane, Y.2    Schwarz, A.3    Luger, T.A.4    Schwarz, T.5
  • 81
    • 4544253996 scopus 로고    scopus 로고
    • Ultraviolet light activates NF-κB through translational inhibition of IκBα synthesis
    • Wu, S.; Tan, M.; Hu, Y.; Wang, J.L.; Scheuner, D.; Kaufman, R.J. Ultraviolet light activates NF-κB through translational inhibition of IκBα synthesis. J. Biol. Chem. 2004, 279, 34898-34902.
    • (2004) J. Biol. Chem. , vol.279 , pp. 34898-34902
    • Wu, S.1    Tan, M.2    Hu, Y.3    Wang, J.L.4    Scheuner, D.5    Kaufman, R.J.6
  • 82
    • 34247628480 scopus 로고    scopus 로고
    • UVB activation of NF-κB in normal human keratinocytes occurs via a unique mechanism
    • Lewis, D.A.; Spandau, D.F. UVB activation of NF-κB in normal human keratinocytes occurs via a unique mechanism. Arch. Dermatol. Res. 2007, 299, 93-101.
    • (2007) Arch. Dermatol. Res. , vol.299 , pp. 93-101
    • Lewis, D.A.1    Spandau, D.F.2
  • 84
    • 27144554627 scopus 로고    scopus 로고
    • Prevention of the ultraviolet B-mediated skin photoaging by a nuclear factor kappaB inhibitor, parthenolide
    • Tanaka, K.; Hasegawa, J.; Asamitsu, K.; Okamoto, T. Prevention of the ultraviolet B-mediated skin photoaging by a nuclear factor kappaB inhibitor, parthenolide. J. Pharmacol. Exp. Ther. 2005, 315, 624-630.
    • (2005) J. Pharmacol. Exp. Ther. , vol.315 , pp. 624-630
    • Tanaka, K.1    Hasegawa, J.2    Asamitsu, K.3    Okamoto, T.4
  • 85
    • 33846272165 scopus 로고    scopus 로고
    • Parthenolide, a natural inhibitor of Nuclear Factor-kappaB, inhibits lung colonization of murine osteosarcoma cells
    • Kishida, Y.; Yoshikawa, H.; Myoui, A. Parthenolide, a natural inhibitor of Nuclear Factor-kappaB, inhibits lung colonization of murine osteosarcoma cells. Clin. Cancer Res. 2007, 13, 59-67.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 59-67
    • Kishida, Y.1    Yoshikawa, H.2    Myoui, A.3
  • 86
    • 34248996892 scopus 로고    scopus 로고
    • Magnolia ovovata extract and its active component magnolol prevent skin photoaging via inhibition of nuclear factor kappaB
    • Tanaka, K.; Hasegawa, J.; Asamitsu, K.; Okamoto, T. Magnolia ovovata extract and its active component magnolol prevent skin photoaging via inhibition of nuclear factor kappaB. Eur. J. Pharmacol. 2007, 565, 212-219.
    • (2007) Eur. J. Pharmacol. , vol.565 , pp. 212-219
    • Tanaka, K.1    Hasegawa, J.2    Asamitsu, K.3    Okamoto, T.4
  • 87
    • 33747866718 scopus 로고    scopus 로고
    • Grape seed proanthocyanidins inhibit UV-radiation-induced oxidative stress and activation of MAPK and NF-κB signaling in human epidermal keratinocytes
    • Mantena, S.K.; Katiyar, S.K. Grape seed proanthocyanidins inhibit UV-radiation-induced oxidative stress and activation of MAPK and NF-κB signaling in human epidermal keratinocytes. Free Radic. Biol. Med. 2006, 40, 1603-1614.
    • (2006) Free Radic. Biol. Med. , vol.40 , pp. 1603-1614
    • Mantena, S.K.1    Katiyar, S.K.2
  • 90
    • 0242691046 scopus 로고    scopus 로고
    • AP-1: A double-edged sword in tumorigenesis
    • Eferl, R.; Wagner, E.F. AP-1: A double-edged sword in tumorigenesis. Nat. Rev. Cancer 2003, 3, 859-868.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 859-868
    • Eferl, R.1    Wagner, E.F.2
  • 91
    • 77949916262 scopus 로고    scopus 로고
    • AP-1 The Jun proteins: Oncogenes or tumor suppressors in disguise
    • Shaulian, E. AP-1 The Jun proteins: Oncogenes or tumor suppressors in disguise? Cell Signal. 2010, 22, 894-899.
    • (2010) Cell Signal , vol.22 , pp. 894-899
    • Shaulian, E.1
  • 92
    • 0036098552 scopus 로고    scopus 로고
    • AP-1 as a regulator of cell life and death
    • Shaulian, E.; Karin, M. AP-1 as a regulator of cell life and death. Nat. Cell Biol. 2002, 4, E131-E136.
    • (2002) Nat. Cell Biol. , vol.4
    • Shaulian, E.1    Karin, M.2
  • 93
    • 0024362088 scopus 로고
    • AP1/Jun function is differentially induced in promotion-sensitive and resistant JB6 cells
    • Bernstein, L.R.; Colburn, N.H. AP1/Jun function is differentially induced in promotion-sensitive and resistant JB6 cells. Science 1989, 244, 566-569.
    • (1989) Science , vol.244 , pp. 566-569
    • Bernstein, L.R.1    Colburn, N.H.2
  • 94
    • 0028300217 scopus 로고
    • Constitutive AP-1 DNA binding and transactivating ability of malignant but not benign mouse epidermal cells
    • Domann, F.E., Jr.; Levy, J.P.; Finch, J.S.; Bowden, G.T. Constitutive AP-1 DNA binding and transactivating ability of malignant but not benign mouse epidermal cells. Mol. Carcinog. 1994, 9, 61-66.
    • (1994) Mol. Carcinog. , vol.9 , pp. 61-66
    • Domann Jr., F.E.1    Levy, J.P.2    Finch, J.S.3    Bowden, G.T.4
  • 95
    • 0027956852 scopus 로고
    • Stable expression of a c-JUN deletion mutant in two malignant mouse epidermal cell lines blocks tumor formation in nude mice
    • Domann, F.E.; Levy, J.P.; Birrer, M.J.; Bowden, G.T. Stable expression of a c-JUN deletion mutant in two malignant mouse epidermal cell lines blocks tumor formation in nude mice. Cell Growth Differ. 1994, 5, 9-16.
    • (1994) Cell Growth Differ , vol.5 , pp. 9-16
    • Domann, F.E.1    Levy, J.P.2    Birrer, M.J.3    Bowden, G.T.4
  • 96
    • 0032575007 scopus 로고    scopus 로고
    • Expression of dominant negative Jun inhibits elevated AP-1 and NF-κB transactivation and suppresses anchorage independent growth of HPV immortalized human keratinocytes
    • Li, J.J.; Rhim, J.S.; Schlegel, R.; Vousden, K.H.; Colburn, N.H. Expression of dominant negative Jun inhibits elevated AP-1 and NF-κB transactivation and suppresses anchorage independent growth of HPV immortalized human keratinocytes. Oncogene 1998, 16, 2711-2721.
    • (1998) Oncogene , vol.16 , pp. 2711-2721
    • Li, J.J.1    Rhim, J.S.2    Schlegel, R.3    Vousden, K.H.4    Colburn, N.H.5
  • 97
    • 0030800330 scopus 로고    scopus 로고
    • Inhibitors of both nuclear factor-kappaB and activator protein-1 activation block the neoplastic transformation response
    • Li, J.J.; Westergaard, C.; Ghosh, P.; Colburn, N.H. Inhibitors of both nuclear factor-kappaB and activator protein-1 activation block the neoplastic transformation response. Cancer Res. 1997, 57, 3569-3576.
    • (1997) Cancer Res , vol.57 , pp. 3569-3576
    • Li, J.J.1    Westergaard, C.2    Ghosh, P.3    Colburn, N.H.4
  • 98
    • 0036606621 scopus 로고    scopus 로고
    • A dominant negative c-jun specifically blocks okadaic acid-induced skin tumor promotion
    • Thompson, E.J.; MacGowan, J.; Young, M.R.; Colburn, N.; Bowden, G.T. A dominant negative c-jun specifically blocks okadaic acid-induced skin tumor promotion. Cancer Res. 2002, 62, 3044-3047.
    • (2002) Cancer Res , vol.62 , pp. 3044-3047
    • Thompson, E.J.1    Macgowan, J.2    Young, M.R.3    Colburn, N.4    Bowden, G.T.5
  • 99
    • 34047264014 scopus 로고    scopus 로고
    • Dominant-negative activator protein 1 (TAM67) targets cyclooxygenase-2 and osteopontin under conditions in which it specifically inhibits tumorigenesis
    • Matthews, C.P.; Birkholz, A.M.; Baker, A.R.; Perella, C.M.; Beck, G.R., Jr.; Young, M.R.; Colburn, N.H. Dominant-negative activator protein 1 (TAM67) targets cyclooxygenase-2 and osteopontin under conditions in which it specifically inhibits tumorigenesis. Cancer Res. 2007, 67, 2430-2438.
    • (2007) Cancer Res , vol.67 , pp. 2430-2438
    • Matthews, C.P.1    Birkholz, A.M.2    Baker, A.R.3    Perella, C.M.4    Beck Jr., G.R.5    Young, M.R.6    Colburn, N.H.7
  • 100
    • 0141430912 scopus 로고    scopus 로고
    • Expression of dominant negative c-jun inhibits ultraviolet B-induced squamous cell carcinoma number and size in an SKH-1 hairless mouse model
    • Cooper, S.J.; MacGowan, J.; Ranger-Moore, J.; Young, M.R.; Colburn, N.H.; Bowden, G.T. Expression of dominant negative c-jun inhibits ultraviolet B-induced squamous cell carcinoma number and size in an SKH-1 hairless mouse model. Mol. Cancer Res. 2003, 1, 848-854.
    • (2003) Mol. Cancer Res. , vol.1 , pp. 848-854
    • Cooper, S.J.1    Macgowan, J.2    Ranger-Moore, J.3    Young, M.R.4    Colburn, N.H.5    Bowden, G.T.6
  • 101
    • 33645862566 scopus 로고    scopus 로고
    • Jun signalling in the epidermis: From developmental defects to psoriasis and skin tumors
    • Zenz, R.; Wagner, E.F. Jun signalling in the epidermis: From developmental defects to psoriasis and skin tumors. Int. J. Biochem. Cell. Biol. 2006, 38, 1043-1049.
    • (2006) Int. J. Biochem. Cell. Biol. , vol.38 , pp. 1043-1049
    • Zenz, R.1    Wagner, E.F.2
  • 102
    • 0033539923 scopus 로고    scopus 로고
    • Activation of p38 MAP kinase and ERK are required for ultraviolet-B induced c-fos gene expression in human keratinocytes
    • Chen, W.; Bowden, G.T. Activation of p38 MAP kinase and ERK are required for ultraviolet-B induced c-fos gene expression in human keratinocytes. Oncogene 1999, 18, 7469-7476.
    • (1999) Oncogene , vol.18 , pp. 7469-7476
    • Chen, W.1    Bowden, G.T.2
  • 103
    • 1242343956 scopus 로고    scopus 로고
    • Induction of MMP-10 and MMP-1 in a squamous cell carcinoma cell line by ultraviolet radiation
    • Ramos, M.C.; Steinbrenner, H.; Stuhlmann, D.; Sies, H.; Brenneisen, P. Induction of MMP-10 and MMP-1 in a squamous cell carcinoma cell line by ultraviolet radiation. Biol. Chem. 2004, 385, 75-86.
    • (2004) Biol. Chem. , vol.385 , pp. 75-86
    • Ramos, M.C.1    Steinbrenner, H.2    Stuhlmann, D.3    Sies, H.4    Brenneisen, P.5
  • 105
    • 12444257799 scopus 로고    scopus 로고
    • Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles
    • Itoh, K.; Wakabayashi, N.; Katoh, Y.; Ishii, T.; O'Connor, T.; Yamamoto, M. Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles. Genes Cells 2003, 8, 379-391.
    • (2003) Genes Cells , vol.8 , pp. 379-391
    • Itoh, K.1    Wakabayashi, N.2    Katoh, Y.3    Ishii, T.4    O'Connor, T.5    Yamamoto, M.6
  • 106
    • 1942455887 scopus 로고    scopus 로고
    • Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles
    • Itoh, K.; Tong, K.I.; Yamamoto, M. Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles. Free Radic. Biol. Med. 2004, 36, 1208-1213.
    • (2004) Free Radic. Biol. Med. , vol.36 , pp. 1208-1213
    • Itoh, K.1    Tong, K.I.2    Yamamoto, M.3
  • 107
    • 0037055265 scopus 로고    scopus 로고
    • Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors
    • Motohashi, H.; O'Connor, T.; Katsuoka, F.; Engel, J.D.; Yamamoto, M. Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors. Gene 2002, 294, 1-12.
    • (2002) Gene , vol.294 , pp. 1-12
    • Motohashi, H.1    O'Connor, T.2    Katsuoka, F.3    Engel, J.D.4    Yamamoto, M.5
  • 108
    • 79954424076 scopus 로고    scopus 로고
    • Nrf2: Control of sensitivity to carcinogens
    • Slocum, S.L.; Kensler, T.W. Nrf2: Control of sensitivity to carcinogens. Arch. Toxicol. 2011, 85, 273-284.
    • (2011) Arch. Toxicol. , vol.85 , pp. 273-284
    • Slocum, S.L.1    Kensler, T.W.2
  • 109
    • 0036318224 scopus 로고    scopus 로고
    • Nrf2 transcription factor, a novel target of keratinocytes growth factor action which regulates gene expression and inflammation in the healing skin wound
    • Braun, S.; Hanselmann, C.; Gassmann, M.G.; auf dem Keller, U.; Born-Berclaz, C.; Chan, K.; Kan, Y.W.; Werner, S. Nrf2 transcription factor, a novel target of keratinocytes growth factor action which regulates gene expression and inflammation in the healing skin wound. Mol. Cell. Biol. 2002, 22, 5492-5505.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 5492-5505
    • Braun, S.1    Hanselmann, C.2    Gassmann, M.G.3    auf dem Keller, U.4    Born-Berclaz, C.5    Chan, K.6    Kan, Y.W.7    Werner, S.8
  • 110
    • 16844375366 scopus 로고    scopus 로고
    • Ultraviolet A irradiation induces NF-E2-related factor 2 activation in dermal fibroblasts: Protective role in UVA-induced apoptosis
    • Hirota, A.; Kawachi, Y.; Itoh, K.; Nakamura, Y.; Xu, X.; Banno, T.; Takahashi, T.; Yamamoto, M.; Otsuka, F. Ultraviolet A irradiation induces NF-E2-related factor 2 activation in dermal fibroblasts: Protective role in UVA-induced apoptosis. J. Invest. Dermatol. 2005, 124, 825-832.
    • (2005) J. Invest. Dermatol. , vol.124 , pp. 825-832
    • Hirota, A.1    Kawachi, Y.2    Itoh, K.3    Nakamura, Y.4    Xu, X.5    Banno, T.6    Takahashi, T.7    Yamamoto, M.8    Otsuka, F.9
  • 111
    • 33749029694 scopus 로고    scopus 로고
    • Low and high dose UVB regulation of transcription factor NF-E2-related factor 2
    • Kannan, S.; Jaiswal, A.K. Low and high dose UVB regulation of transcription factor NF-E2-related factor 2. Cancer Res. 2006, 66, 8421-8429.
    • (2006) Cancer Res , vol.66 , pp. 8421-8429
    • Kannan, S.1    Jaiswal, A.K.2
  • 112
    • 33847036712 scopus 로고    scopus 로고
    • Electrophilic chemicals but not UV irradiation or reactive oxygen species activate Nrf2 in keratinocytes in vitro and in vivo
    • Durchdewald, M.; Beyer, T.A.; Johnson, D.A.; Johnson, J.A.; Werner, S.; auf dem Keller, U. Electrophilic chemicals but not UV irradiation or reactive oxygen species activate Nrf2 in keratinocytes in vitro and in vivo. J. Invest. Dermatol. 2007, 127, 646-653.
    • (2007) J. Invest. Dermatol. , vol.127 , pp. 646-653
    • Durchdewald, M.1    Beyer, T.A.2    Johnson, D.A.3    Johnson, J.A.4    Werner, S.5    auf dem Keller, U.6
  • 116
    • 45349091113 scopus 로고    scopus 로고
    • Attenuation of UVB-induced sunburn reaction and oxidative DNA damage with no alterations in UVB-induced skin carcinogenesis in Nrf2 gene-deficient mice
    • Kawachi, Y.; Xu, X.; Taguchi, S.; Sakurai, H.; Nakamura, Y.; Ishii, Y.; Fujisawa, Y.; Furuta, J.; Takahashi, T.; Itoh, K.; et al. Attenuation of UVB-induced sunburn reaction and oxidative DNA damage with no alterations in UVB-induced skin carcinogenesis in Nrf2 gene-deficient mice. J. Invest. Dermatol. 2008, 128, 1773-1779.
    • (2008) J. Invest. Dermatol. , vol.128 , pp. 1773-1779
    • Kawachi, Y.1    Xu, X.2    Taguchi, S.3    Sakurai, H.4    Nakamura, Y.5    Ishii, Y.6    Fujisawa, Y.7    Furuta, J.8    Takahashi, T.9    Itoh, K.10
  • 117
    • 2442542312 scopus 로고    scopus 로고
    • PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress
    • Cullinan, S.B.; Diehl, J.A. PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress. J. Biol. Chem. 2004, 279, 20108-20117.
    • (2004) J. Biol. Chem. , vol.279 , pp. 20108-20117
    • Cullinan, S.B.1    Diehl, J.A.2
  • 118
    • 0037044791 scopus 로고    scopus 로고
    • Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription
    • Huang, H.C.; Nguyen, T.; Pickett, C.B. Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription. J. Biol. Chem. 2002, 277, 42769-42774.
    • (2002) J. Biol. Chem. , vol.277 , pp. 42769-42774
    • Huang, H.C.1    Nguyen, T.2    Pickett, C.B.3
  • 119
    • 0034704079 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism
    • Yu, R.; Chen, C.; Mo, Y.Y.; Hebbar, V.; Owuor, E.D.; Tan, T.H.; Kong, A.N. Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism. J. Biol. Chem. 2000, 275, 39907-39913.
    • (2000) J. Biol. Chem. , vol.275 , pp. 39907-39913
    • Yu, R.1    Chen, C.2    Mo, Y.Y.3    Hebbar, V.4    Owuor, E.D.5    Tan, T.H.6    Kong, A.N.7
  • 120
    • 0034723357 scopus 로고    scopus 로고
    • p38 mitogen-activated protein kinase negatively regulates the induction of phase II drug-metabolizing enzymes that detoxify carcinogens
    • Yu, R.; Mandlekar, S.; Lei, W.; Fahl, W.E.; Tan, T.H.; Kong, A.N. p38 mitogen-activated protein kinase negatively regulates the induction of phase II drug-metabolizing enzymes that detoxify carcinogens. J. Biol. Chem. 2000, 275, 2322-2327.
    • (2000) J. Biol. Chem. , vol.275 , pp. 2322-2327
    • Yu, R.1    Mandlekar, S.2    Lei, W.3    Fahl, W.E.4    Tan, T.H.5    Kong, A.N.6
  • 121
    • 77958114117 scopus 로고    scopus 로고
    • Regulation of NF-E2-related factor 2 signaling for cancer chemoprevention: Antioxidant coupled with antiinflammatory
    • Hu, R.; Saw, C.L.; Yu, R.; Kong, A.N. Regulation of NF-E2-related factor 2 signaling for cancer chemoprevention: Antioxidant coupled with antiinflammatory. Antioxid. Redox Signal 2010, 13, 1679-1698.
    • (2010) Antioxid. Redox Signal. , vol.13 , pp. 1679-1698
    • Hu, R.1    Saw, C.L.2    Yu, R.3    Kong, A.N.4
  • 124
    • 0030973579 scopus 로고    scopus 로고
    • Transcription factors of the NFAT family: Regulation and function
    • Rao, A.; Luo, C.; Hogan, P.G. Transcription factors of the NFAT family: Regulation and function. Annu. Rev. Immunol. 1997, 15, 707-747.
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 707-747
    • Rao, A.1    Luo, C.2    Hogan, P.G.3
  • 125
    • 0141483523 scopus 로고    scopus 로고
    • Transcriptional regulation by calcium, calcineurin, and NFAT
    • Hogan, P.G.; Chen, L.; Nardone, J.; Rao, A. Transcriptional regulation by calcium, calcineurin, and NFAT. Genes. Dev. 2003, 17, 2205-2232.
    • (2003) Genes. Dev. , vol.17 , pp. 2205-2232
    • Hogan, P.G.1    Chen, L.2    Nardone, J.3    Rao, A.4
  • 127
    • 34248325651 scopus 로고    scopus 로고
    • Cyclooxygenase-2 deficiency increases epidermal apoptosis and impairs recovery following acute UVB exposure
    • Akunda, J.K.; Chun, K.S.; Sessoms, A.R.; Lao, H.C.; Fischer, S.M.; Langenbach, R. Cyclooxygenase-2 deficiency increases epidermal apoptosis and impairs recovery following acute UVB exposure. Mol. Carcinog. 2007, 46, 354-362.
    • (2007) Mol. Carcinog. , vol.46 , pp. 354-362
    • Akunda, J.K.1    Chun, K.S.2    Sessoms, A.R.3    Lao, H.C.4    Fischer, S.M.5    Langenbach, R.6
  • 128
    • 57349155737 scopus 로고    scopus 로고
    • NFAT regulates induction of COX-2 and apoptosis of keratinocytes in response to ultraviolet radiation exposure
    • Flockhart, R.J.; Diffey, B.L.; Farr, P.M.; Lloyd, J.; Reynolds, N.J. NFAT regulates induction of COX-2 and apoptosis of keratinocytes in response to ultraviolet radiation exposure. FASEB J. 2008, 22, 4218-4227.
    • (2008) FASEB J , vol.22 , pp. 4218-4227
    • Flockhart, R.J.1    Diffey, B.L.2    Farr, P.M.3    Lloyd, J.4    Reynolds, N.J.5
  • 129
    • 0032323616 scopus 로고    scopus 로고
    • Animals under the sun: Effects of ultraviolet radiation on mammalian skin
    • Slominski, A.; Pawelek, J. Animals under the sun: Effects of ultraviolet radiation on mammalian skin. Clin. Dermatol. 1998, 16, 503-515.
    • (1998) Clin. Dermatol. , vol.16 , pp. 503-515
    • Slominski, A.1    Pawelek, J.2
  • 131
    • 18744402160 scopus 로고    scopus 로고
    • Regulation of the human melanocortin 1 receptor expression in epidermal melanocytes by paracrine and endocrine factors and by ultraviolet radiation
    • Scott, M.C.; Suzuki, I.; Abdel-Malek, Z.A. Regulation of the human melanocortin 1 receptor expression in epidermal melanocytes by paracrine and endocrine factors and by ultraviolet radiation. Pigment Cell Res. 2002, 15, 433-439.
    • (2002) Pigment Cell Res , vol.15 , pp. 433-439
    • Scott, M.C.1    Suzuki, I.2    Abdel-Malek, Z.A.3
  • 132
    • 10944271997 scopus 로고    scopus 로고
    • UV-induced expression of key component of the tanning process, the POMC and MC1R genes, is dependent on the p-38-activated upstream stimulating factor-1 (USF-1)
    • Corre, S.; Primot, A.; Sviderskaya, E.; Bennett, D.C.; Vaulont, S.; Goding, C.R.; Galibert, M.D. UV-induced expression of key component of the tanning process, the POMC and MC1R genes, is dependent on the p-38-activated upstream stimulating factor-1 (USF-1). J. Biol. Chem. 2004, 279, 51226-51233.
    • (2004) J. Biol. Chem. , vol.279 , pp. 51226-51233
    • Corre, S.1    Primot, A.2    Sviderskaya, E.3    Bennett, D.C.4    Vaulont, S.5    Goding, C.R.6    Galibert, M.D.7
  • 133
    • 14644419663 scopus 로고    scopus 로고
    • Ultraviolet radiation and skin aging: Roles of reactive oxygen species, inflammation and protease activation, and strategies for prevention of inflammation-induced matrix degradation-a review
    • Pillai, S.; Oresajo, C.; Hayward, J. Ultraviolet radiation and skin aging: Roles of reactive oxygen species, inflammation and protease activation, and strategies for prevention of inflammation-induced matrix degradation-a review. Int. J. Cosmet. Sci. 2005, 27, 17-34.
    • (2005) Int. J. Cosmet. Sci. , vol.27 , pp. 17-34
    • Pillai, S.1    Oresajo, C.2    Hayward, J.3
  • 134
    • 0030952750 scopus 로고    scopus 로고
    • Differential stimulation of ERK and JNK activities by ultraviolet B irradiation and epidermal growth factor in human keratinocytes
    • Assefa, Z.; Garmyn, M.; Bouillon, R.; Merlevede, W.; Vandenheede, J.R.; Agostinis, P. Differential stimulation of ERK and JNK activities by ultraviolet B irradiation and epidermal growth factor in human keratinocytes. J. Invest. Dermatol. 1997, 108, 886-891.
    • (1997) J. Invest. Dermatol. , vol.108 , pp. 886-891
    • Assefa, Z.1    Garmyn, M.2    Bouillon, R.3    Merlevede, W.4    Vandenheede, J.R.5    Agostinis, P.6
  • 135
    • 0028329953 scopus 로고
    • JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
    • Derijard, B.; Hibi, M.; Wu, I.H.; Barrett, T.; Su, B.; Deng, T.; Karin, M.; Davis, R.J. JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 1994, 76, 1025-1037.
    • (1994) Cell , vol.76 , pp. 1025-1037
    • Derijard, B.1    Hibi, M.2    Wu, I.H.3    Barrett, T.4    Su, B.5    Deng, T.6    Karin, M.7    Davis, R.J.8
  • 136
    • 0029056455 scopus 로고
    • The effect of acute and chronic photodamage on gene expression in human keratinocytes
    • Garmyn, M.; Degreef, H.; Gilchrest, B.A. The effect of acute and chronic photodamage on gene expression in human keratinocytes. Dermatology 1995, 190, 305-308.
    • (1995) Dermatology , vol.190 , pp. 305-308
    • Garmyn, M.1    Degreef, H.2    Gilchrest, B.A.3
  • 138
    • 0030980317 scopus 로고    scopus 로고
    • Effects of interferons on the production of interleukin-6 and interleukin-8 in human keratinocytes
    • Fujisawa, H.; Wang, B.; Sauder, D.N.; Kondo, S. Effects of interferons on the production of interleukin-6 and interleukin-8 in human keratinocytes. J. Interferon Cytokine Res. 1997, 17, 347-353.
    • (1997) J. Interferon Cytokine Res. , vol.17 , pp. 347-353
    • Fujisawa, H.1    Wang, B.2    Sauder, D.N.3    Kondo, S.4
  • 139
    • 0030803241 scopus 로고    scopus 로고
    • Down-regulation of interferon gamma-activated STAT1 by UV light
    • Aragane, Y.; Kulms, D.; Luger, T.A.; Schwarz, T. Down-regulation of interferon gamma-activated STAT1 by UV light. Proc. Natl. Acad. Sci. USA 1997, 94, 11490-11495.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 11490-11495
    • Aragane, Y.1    Kulms, D.2    Luger, T.A.3    Schwarz, T.4
  • 141
    • 0037022571 scopus 로고    scopus 로고
    • Analysis of the ultraviolet B response in primary human keratinocytes using oligonucleotide microarrays
    • Sesto, A.; Navarro, M.; Burslem, F.; Jorcano, J.L. Analysis of the ultraviolet B response in primary human keratinocytes using oligonucleotide microarrays. Proc. Natl. Acad. Sci. USA 2002, 99, 2965-2970.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 2965-2970
    • Sesto, A.1    Navarro, M.2    Burslem, F.3    Jorcano, J.L.4
  • 142
  • 143
    • 2142765862 scopus 로고    scopus 로고
    • Microarray analysis of UVB-regulated genes in keratinocytes: Downregulation of angiogenesis inhibitor thrombospondin-1
    • Howell, B.G.; Wang, B.; Freed, I.; Mamelak, A.J.; Watanabe, H.; Sauder, D.N. Microarray analysis of UVB-regulated genes in keratinocytes: Downregulation of angiogenesis inhibitor thrombospondin-1. J. Dermatol. Sci. 2004, 34, 185-194.
    • (2004) J. Dermatol. Sci. , vol.34 , pp. 185-194
    • Howell, B.G.1    Wang, B.2    Freed, I.3    Mamelak, A.J.4    Watanabe, H.5    Sauder, D.N.6
  • 144
    • 80053016986 scopus 로고    scopus 로고
    • Microarray profiling of gene expression in human keratinocytes suggests a new protective activity against UV-induced DNA damage for a compound previously known to interact with SCF-KIT signalling pathway
    • Serre, C.; Lebleu, A.; Bergeron, L.; Plantivaux, A.; Botto, J.M.; Dal, F.C.; Domloge, N. Microarray profiling of gene expression in human keratinocytes suggests a new protective activity against UV-induced DNA damage for a compound previously known to interact with SCF-KIT signalling pathway. Int. J. Cosmet. Sci. 2011, 33, 398-407.
    • (2011) Int. J. Cosmet. Sci. , vol.33 , pp. 398-407
    • Serre, C.1    Lebleu, A.2    Bergeron, L.3    Plantivaux, A.4    Botto, J.M.5    Dal, F.C.6    Domloge, N.7
  • 145
    • 5044226457 scopus 로고    scopus 로고
    • A novel microarray to evaluate stress-related genes in skin: Effect of ultraviolet light radiation
    • Pisarchik, A.; Wortsman, J.; Slominski, A. A novel microarray to evaluate stress-related genes in skin: Effect of ultraviolet light radiation. Gene 2004, 341, 199-207.
    • (2004) Gene , vol.341 , pp. 199-207
    • Pisarchik, A.1    Wortsman, J.2    Slominski, A.3
  • 147
    • 0034854311 scopus 로고    scopus 로고
    • Expression profiling of cancer-related genes in human keratinocytes following non-lethal ultraviolet B irradiation
    • Murakami, T.; Fujimoto, M.; Ohtsuki, M.; Nakagawa, H. Expression profiling of cancer-related genes in human keratinocytes following non-lethal ultraviolet B irradiation. J. Dermatol. Sci. 2001, 27, 121-129.
    • (2001) J. Dermatol. Sci. , vol.27 , pp. 121-129
    • Murakami, T.1    Fujimoto, M.2    Ohtsuki, M.3    Nakagawa, H.4
  • 148
    • 0037762589 scopus 로고    scopus 로고
    • Genome-wide comparison of human keratinocyte and squamous cell carcinoma responses to UVB irradiation: Implications for skin and epithelial cancer
    • Dazard, J.E.; Gal, H.; Amariglio, N.; Rechavi, G.; Domany, E.; Givol, D. Genome-wide comparison of human keratinocyte and squamous cell carcinoma responses to UVB irradiation: Implications for skin and epithelial cancer. Oncogene 2003, 22, 2993-3006.
    • (2003) Oncogene , vol.22 , pp. 2993-3006
    • Dazard, J.E.1    Gal, H.2    Amariglio, N.3    Rechavi, G.4    Domany, E.5    Givol, D.6
  • 149
    • 34447643536 scopus 로고    scopus 로고
    • The melanocyte and the epidermal melanin unit: An expanded concept
    • Nordlund, J.J. The melanocyte and the epidermal melanin unit: An expanded concept. Dermatol. Clin. 2007, 25, 271-281.
    • (2007) Dermatol. Clin. , vol.25 , pp. 271-281
    • Nordlund, J.J.1
  • 150
    • 0034793435 scopus 로고    scopus 로고
    • Distinct melanogenic response of human melanocytes in mono-culture, in co-culture with keratinocytes and in reconstructed epidermis, to UV exposure
    • Duval, C.; Regnier, M.; Schmidt, R. Distinct melanogenic response of human melanocytes in mono-culture, in co-culture with keratinocytes and in reconstructed epidermis, to UV exposure. Pigment Cell Res. 2001, 14, 348-355.
    • (2001) Pigment Cell Res. , vol.14 , pp. 348-355
    • Duval, C.1    Regnier, M.2    Schmidt, R.3
  • 151
    • 18744415966 scopus 로고    scopus 로고
    • Keratinocytes control the pheo/eumelanin ratio in cultured normal human melanocytes
    • Duval, C.; Smit, N.P.; Kolb, A.M.; Regnier, M.; Pavel, S.; Schmidt, R. Keratinocytes control the pheo/eumelanin ratio in cultured normal human melanocytes. Pigment Cell Res. 2002, 15, 440-446.
    • (2002) Pigment Cell Res. , vol.15 , pp. 440-446
    • Duval, C.1    Smit, N.P.2    Kolb, A.M.3    Regnier, M.4    Pavel, S.5    Schmidt, R.6
  • 152
    • 0033217682 scopus 로고    scopus 로고
    • Keratinocyte-melanocyte co-cultures and pigmented reconstructed human epidermis: Models to study modulation of melanogenesis
    • Regnier, M.; Duval, C.; Galey, J.B.; Philippe, M.; Lagrange, A.; Tuloup, R.; Schmidt, R. Keratinocyte-melanocyte co-cultures and pigmented reconstructed human epidermis: Models to study modulation of melanogenesis. Cell Mol. Biol. 1999, 45, 969-980.
    • (1999) Cell Mol. Biol , vol.45 , pp. 969-980
    • Regnier, M.1    Duval, C.2    Galey, J.B.3    Philippe, M.4    Lagrange, A.5    Tuloup, R.6    Schmidt, R.7
  • 153
    • 0346786217 scopus 로고    scopus 로고
    • Genetics of hair and skin color
    • Rees, J.L. Genetics of hair and skin color. Annu. Rev. Genet. 2003, 37, 67-90.
    • (2003) Annu. Rev. Genet. , vol.37 , pp. 67-90
    • Rees, J.L.1
  • 154
    • 0029086678 scopus 로고
    • Comparison of the responses of human melanocytes with different melanin contents to ultraviolet B irradiation
    • Barker, D.; Dixon, K.; Medrano, E.E.; Smalara, D.; Im, S.; Mitchell, D.; Babcock, G.; Abdel-Malek, Z.A. Comparison of the responses of human melanocytes with different melanin contents to ultraviolet B irradiation. Cancer Res. 1995, 55, 4041-4046.
    • (1995) Cancer Res , vol.55 , pp. 4041-4046
    • Barker, D.1    Dixon, K.2    Medrano, E.E.3    Smalara, D.4    Im, S.5    Mitchell, D.6    Babcock, G.7    Abdel-Malek, Z.A.8
  • 155
    • 0033200066 scopus 로고    scopus 로고
    • Ultraviolet radiation induces p16CDKN2A expression in human skin
    • Pavey, S.; Conroy, S.; Russell, T.; Gabrielli, B. Ultraviolet radiation induces p16CDKN2A expression in human skin. Cancer Res. 1999, 59, 4185-4189.
    • (1999) Cancer Res , vol.59 , pp. 4185-4189
    • Pavey, S.1    Conroy, S.2    Russell, T.3    Gabrielli, B.4
  • 156
    • 0037714871 scopus 로고    scopus 로고
    • Is p53 gene mutation an indicatior of the biological behaviors of recurrence of hepatocellular carcinoma?
    • Sheen, I.S.; Jeng, K.S.; Wu, J.Y. Is p53 gene mutation an indicatior of the biological behaviors of recurrence of hepatocellular carcinoma? World J. Gastroenterol. 2003, 9, 1202-1207.
    • (2003) World J. Gastroenterol. , vol.9 , pp. 1202-1207
    • Sheen, I.S.1    Jeng, K.S.2    Wu, J.Y.3
  • 157
    • 0036646113 scopus 로고    scopus 로고
    • UVB-mediated activation of p38 mitogen-activated protein kinase enhances resistance of normal human keratinocytes to apoptosis by stabilizing cytoplasmic p53
    • Chouinard, N.; Valerie, K.; Rouabhia, M.; Huot, J. UVB-mediated activation of p38 mitogen-activated protein kinase enhances resistance of normal human keratinocytes to apoptosis by stabilizing cytoplasmic p53. Biochem. J. 2002, 365, 133-145.
    • (2002) Biochem. J. , vol.365 , pp. 133-145
    • Chouinard, N.1    Valerie, K.2    Rouabhia, M.3    Huot, J.4
  • 160
    • 0037713158 scopus 로고    scopus 로고
    • Significance of the melanocortin 1 receptor in regulating human melanocyte pigmentation, proliferation, and survival
    • Kadekaro, A.L.; Kanto, H.; Kavanagh, R.; Abdel-Malek, Z.A. Significance of the melanocortin 1 receptor in regulating human melanocyte pigmentation, proliferation, and survival. Ann. N.Y. Acad. Sci. 2003, 994, 359-365.
    • (2003) Ann. N.Y. Acad. Sci. , vol.994 , pp. 359-365
    • Kadekaro, A.L.1    Kanto, H.2    Kavanagh, R.3    Abdel-Malek, Z.A.4
  • 161
    • 0346888664 scopus 로고    scopus 로고
    • Ultraviolet A and B differently induce intracellular protein expression in human skin melanocytes-a speculation of separate pathways in initiation of melanoma
    • Zhang, H.; Rosdahl, I. Ultraviolet A and B differently induce intracellular protein expression in human skin melanocytes-a speculation of separate pathways in initiation of melanoma. Carcinogenesis 2003, 24, 1929-1934.
    • (2003) Carcinogenesis , vol.24 , pp. 1929-1934
    • Zhang, H.1    Rosdahl, I.2
  • 162
    • 0035671308 scopus 로고    scopus 로고
    • Identification by cDNA microarray technology of genes modulated by artificial ultraviolet radiation in normal human melanocytes: Relation to melanocarcinogenesis
    • Valery, C.; Grob, J.J.; Verrando, P. Identification by cDNA microarray technology of genes modulated by artificial ultraviolet radiation in normal human melanocytes: Relation to melanocarcinogenesis. J. Invest. Dermatol. 2001, 117, 1471-1482.
    • (2001) J. Invest. Dermatol. , vol.117 , pp. 1471-1482
    • Valery, C.1    Grob, J.J.2    Verrando, P.3
  • 165
    • 33750072347 scopus 로고    scopus 로고
    • Expression profiling of UVB response in melanocytes identifies a set of p53-target genes
    • Yang, G.; Zhang, G.; Pittelkow, M.R.; Ramoni, M.; Tsao, H. Expression profiling of UVB response in melanocytes identifies a set of p53-target genes. J. Invest. Dermatol. 2006, 126, 2490-2506.
    • (2006) J. Invest. Dermatol. , vol.126 , pp. 2490-2506
    • Yang, G.1    Zhang, G.2    Pittelkow, M.R.3    Ramoni, M.4    Tsao, H.5
  • 166
    • 0032694150 scopus 로고    scopus 로고
    • Role of UVA in the pathogenesis of melanoma and non-melanoma skin cancer. A short review
    • Runger, T.M. Role of UVA in the pathogenesis of melanoma and non-melanoma skin cancer. A short review. Photodermatol. Photoimmunol. Photomed. 1999, 15, 212-216.
    • (1999) Photodermatol. Photoimmunol. Photomed. , vol.15 , pp. 212-216
    • Runger, T.M.1
  • 167
    • 0347504491 scopus 로고    scopus 로고
    • The use of reconstructed human skin to evaluate UV-induced modifications and sunscreen efficacy
    • Duval, C.; Schmidt, R.; Regnier, M.; Facy, V.; Asselineau, D.; Bernerd, F. The use of reconstructed human skin to evaluate UV-induced modifications and sunscreen efficacy. Exp. Dermatol. 2003, 12, 64-70.
    • (2003) Exp. Dermatol. , vol.12 , pp. 64-70
    • Duval, C.1    Schmidt, R.2    Regnier, M.3    Facy, V.4    Asselineau, D.5    Bernerd, F.6
  • 169
    • 1842788162 scopus 로고    scopus 로고
    • The basal layer in human squamous tumors harbors more UVA than UVB fingerprint mutations: A role for UVA in human skin carcinogenesis
    • Agar, N.S.; Halliday, G.M.; Barnetson, R.S.; Ananthaswamy, H.N.; Wheeler, M.; Jones, A.M. The basal layer in human squamous tumors harbors more UVA than UVB fingerprint mutations: A role for UVA in human skin carcinogenesis. Proc. Natl. Acad. Sci. USA 2004, 101, 4954-4959.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 4954-4959
    • Agar, N.S.1    Halliday, G.M.2    Barnetson, R.S.3    Ananthaswamy, H.N.4    Wheeler, M.5    Jones, A.M.6
  • 170
    • 77952428954 scopus 로고    scopus 로고
    • Regulation of human skin pigmentation in situ by repetitive UV exposure: Molecular characterization of responses to UVA and/or UVB
    • Choi, W.; Miyamura, Y.; Wolber, R.; Smuda, C.; Reinhold, W.; Liu, H.; Kolbe, L.; Hearing, V.J. Regulation of human skin pigmentation in situ by repetitive UV exposure: Molecular characterization of responses to UVA and/or UVB. J. Invest. Dermatol. 2010, 130, 1685-1696.
    • (2010) J. Invest. Dermatol. , vol.130 , pp. 1685-1696
    • Choi, W.1    Miyamura, Y.2    Wolber, R.3    Smuda, C.4    Reinhold, W.5    Liu, H.6    Kolbe, L.7    Hearing, V.J.8
  • 172
    • 77957819949 scopus 로고    scopus 로고
    • Different oxidative stress response in keratinocytes and fibroblasts of reconstructed skin exposed to non extreme daily-ultraviolet radiation
    • Marionnet, C.; Pierrard, C.; Lejeune, F.; Sok, J.; Thomas, M.; Bernerd, F. Different oxidative stress response in keratinocytes and fibroblasts of reconstructed skin exposed to non extreme daily-ultraviolet radiation. PLoS One 2010, 5, e12059.
    • (2010) PLoS One , vol.5
    • Marionnet, C.1    Pierrard, C.2    Lejeune, F.3    Sok, J.4    Thomas, M.5    Bernerd, F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.