Regulation of the human melanocortin 1 receptor expression in epidermal melanocytes by paracrine and endocrine factors and by ultraviolet radiation

Pigment Cell Research

Volumn 15, Issue 6, 2002, Pages 433-439

  Scott, M Cathy ^a   Suzuki, Itaru ^b   Abdel Malek, Zalfa A ^a  

^a UNIVERSITY OF CINCINNATI   (United States)

^b POLA Laboratories   (Japan)

Author keywords

Growth factors; Hormones; Melanocortin 1 receptor gene

Indexed keywords

ALPHA INTERMEDIN; CARCINOGEN; CORTICOTROPIN RECEPTOR; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FIBROBLAST GROWTH FACTOR 2; MELANOCORTIN RECEPTOR; MESSENGER RNA; PHORBOL 13 ACETATE 12 MYRISTATE;

ARTICLE; CELL CULTURE; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION; GENETICS; HUMAN; MELANOCYTE; METABOLISM; PARACRINE SIGNALING; PHYSIOLOGY; RADIATION EXPOSURE; ULTRAVIOLET RADIATION;

ALPHA-MSH; CARCINOGENS; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION; HUMANS; MELANOCYTES; PARACRINE COMMUNICATION; RECEPTORS, CORTICOTROPIN; RECEPTORS, MELANOCORTIN; RNA, MESSENGER; TETRADECANOYLPHORBOL ACETATE; ULTRAVIOLET RAYS;

AGOUTI;

EID: 18744402160     PISSN: 08935785     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0749.2002.02051.x     Document Type: Article

References (51)

1. Mountjoy KG, Robbins LS, Mortrud MT, Cone RD. The cloning of a family of genes that encode the melanocortin receptors. Science 1992;257:1248-1251
2. Chhajlani V, Wikberg JES. Molecular cloning and expression of the human melanocyte stimulating hormone receptor cDNA. FEBS Lett 1992;309:417-420
3. Abdel-Malek Z, Swope VB, Suzuki I, Akcali C, Harriger MD, Boyce ST, Urabe K, Hearing VJ. Mitogenic and melanogenic stimulation of normal human melanocytes by melanotropic peptides. Proc Natl Acad Sci USA 1995;92:1789-1793
4. Suzuki I, Cone R, Im S, Nordlund J, Abdel-Malek Z. Binding capacity and activation of the MC1 receptors by melanotropic hormones correlate directly with their mitogenic and melanogenic effects on human melanocytes. Endocrinology 1996;137:1627-1633
5. Suzuki I, Tada A, Ollmann MM, Barsh GS, Im S, Lamoreux ML, Hearing VJ, Nordlund J, Abdel-Malek ZA. Agouti signaling protein inhibits melanogenesis and the response of human melanocytes to α-melanotropin. J Invest Dermatol 1997;108:838-842
6. Fuller BB, Lunsford JB, Iman DS. α-melanocyte-stimulating hormone regulation of tyrosinase in Cloudman S-91 mouse melanoma cell cultures. J Biol Chem 1987;262:4024-4033
7. Tada A, Pereira E, Beitner Johnson D, Abdel-Malek ZA. Mitogen and stress induced signaling pathways in normal human melanocytes. J Invest Dermatol 2002;118:316-322
8. Geschwind II, Huseby RA, Nishioka R. The effect of melanocyte-stimulating hormone on coat color in the mouse. Recent Prog Horm Res 1972;28:91-130
9. Tamate HB, Takeuchi T. Action of the e locus of mice in the response of phaeomelanic hair follicles to α-melanocyte-stimulating hormone in vitro. Science 1984;224:1241-1242
10. 7 α-Melanocyte-stimulating hormone increases the eumelanin: Phaeomelanin ratio in cultured human melanocytes. J Invest Dermatol 1995;104:83-85
11. Box NF, Wyeth JR, O'Gorman LE, Martin NG, Sturm RA. Characterization of melanocyte stimulating hormone receptor variant alleles in twins with red hair. Hum Mol Genet 1997;6:1891-1897
12. Smith R, Healy E, Siddiqui S, Flanagan N, Steijlen PM, Rosdahl I, Jacques JP, Rogers S, Turner R, Jackson IJ, Birch-Machin MA, Rees JL. Melanocortin 1 receptor variants in Irish population. J Invest Dermatol 1998;111:119-122
13. Schiöth HB, Phillips SR, Rudzish R, Birch-Machin MA, Wikberg JES, Rees JL. Loss of function mutations of the human melanocortin 1 receptor are common and are associated with red hair. Biochem Biophys Res Commun 1999;260:488-491
14. Scott MC, Wakamatsu K, Ito S, Kadekaro AL, Kobayashi N, Groden J, Kavanagh R, Takakuwa T, Virador V, Hearing VJ, Abdel-Malek ZA. Human melanocortin 1 receptor variants, receptor function and melanocyte response to ultraviolet radiation. J Cell Sci 2002;115:2349-2355
15. Bastiaens MT, ter Huurne JAC, Kielich C, Gruis NA, Westendorp RGJ, Vermeer BJ, Bouwes Bavinck JN. Melanocortin-1 receptor gene variants determine the risk of non-melanoma skin cancer independent of fair skin type and red hair. Am J Hum Genet 2001;68:884-894
16. Box NF, Duffy DL, Irving RE, Russell A, Chen W, Griffiths LR, Parsons PG, Green AC, Sturm RA. Melanocortin-1 receptor genotype is a risk factor for basal and squamous cell carcinoma. J Invest Dermatol 2001;116:224-229
17. Kennedy C, ter Huurne J, Berkhout M, Gruis N, Bastiaens M, Bergman W, Willemze R, Bouwes Bavinck JN. Melanocortin 1 receptor (MC1R gene variants are associated with an increased risk for cutaneous melanoma which is largely independent of skin type and hair color. J Invest Dermatol 2001;117:294-300
18. Ranson M, Posen S, Mason RS. Human melanocytes as a target tissue for hormones: In vitro studies with 1α-25,dihydroxyvitamin D3, α-melanocyte stimulating hormone, and α-estradiol. J Invest Dermatol 1988;91:593-598
19. Swope VB, Abdel-Malek ZA, Kassem L, Nordlund JJ. Interleukins 1α and 6 and tumor necrosis factor-α are paracrine inhibitors of human melanocyte proliferation and melanogenesis. J Invest Dermatol 1991;96:180-185
20. McLeod SD, Ranson M, Mason RS. Effects of estrogens on human melanocytes in vitro. J Steroid Biochem 1994;49:9-14
21. Imokawa G, Miyagishi M, Yada Y. Endothelin-1 as a new melanogen. Coordinated expression of its gene and the tyrosinase gene in UVB-exposed human epidermis. J Invest Dermatol 1995;105:32-37
22. Tada A, Suzuki I, Im S, Davis MB, Cornelius J, Babcock G, Nordlund JJ, Abdel-Malek ZA. Endothelin-1 is a paracrine growth factor that modulates melanogenesis of human melanocytes and participates in their responses to ultraviolet radiation. Cell Growth Differ 1998;9:575-584
23. Kadono S, Manaka I, Kawashima M, Kobayashi T, Imokawa G. The role of the epidermal endothelin cascade in the hyperpigmentation mechanism of lentigo senilis. J Invest Dermatol 2001;116:571-577
24. Chakraborty AK, Orlow SJ, Bolognia JL, Pawelek JM. Strucrural/functional relationships between internal and external MSH receptors: Modulation of expression in Cloudman melanoma cells by UVB radiation. J Cell Physiol 1991;147:1-6
25. Chakraborty A, Slominski A, Erinak G, Hwang J, Pawelek J. Ultraviolet B and melanocyte stimulating hormone (MSH) stimulate mRNA production for α-MSH receptors and proopiomelanocortin-derived peptides in mouse melanoma cells and transformed keratinocytes. J Invest Dermatol 1995;105:655-659
26. vy/- mice; Ectopic expression of the agouti gene. FASEB J 1994;8:479-488
27. Barsh GS. The genetics of pigmentation: From fancy genes to complex traits. Trends Genet 1996;12:299-305
28. Imokawa G, Yada Y, Miyagishi M. Endothelins secreted from human keratinocytes are intrinsic mitogens for human melanocytes. J Biol Chem 1992;267:24675-24680
29. Abdel-Malek Z, Swope VB, Pallas J, Krug K, Nordlund JJ. Mitogenic, melanogenic and cAMP responses of cultured neonatal human melanocytes to commonly used mitogens. J Cell Physiol 1992;150:416-425
30. Halaban R, Langdon R, Birchall N, Cuono C, Baird A, Scott G, Moellmann G, McGuire J. Basic fibroblast growth factor from human keratinocytes is a natural mitogen for melanocytes. J Cell Biol 1988;107:1611-1619
31. Swope VB, Medrano EE, Smalara D, Abdel-Malek Z. Long-term proliferation of human melanocytes is supported by the physiologic mitogens α-melanotropin, endothelin-1, and basic fibroblast growth factor. Exp Cell Res 1995;217:453-459
32. Snell RS. The pigmentary changes occurring in the breast skin during pregnancy and following estrogen treatment. J Invest Dermatol 1964;43:181-186
33. Bischitz PG, Snell RS. A study of the effect of ovariectomy, oestrogen and progesterone on the melanocytes and melanin in the skin of the female guinea pig. J Endocrinol 1960;20:312
34. Levine N, Hori Y, Kubota Y. Acquired hypermelanotic disorders. In: Levine N. Pigmentation and Pigmentary Disorders. Bota Raton: CRC Press: 1993. pp. 211-238
35. Moro O, Ideta R, Ifuku O. Characterization of the promoter region of the human melanocortin-1 receptor (MC1R) gene. Biochem Biophys Res Comm 1999;262:452-460
36. Adachi S, Morii E, Kim DK, Ogihara H, Jippo T, Ito A, Lee YM, Kitamura Y. Involvement of mi-transcription factor in expression of alpha-melanocyte-stimulating hormone receptor in cultured mast cells of mice. J Immunol 2000;164:855-860
37. Donatien PD, Hunt G, Pieron C, Lunec J, Taïeb A, Thody AJ. The expression of functional MSH receptors on cultured human melanocytes. Arch Dermatol Res 1992;284:424-426
38. Medrano EE, Nordlund JJ. Successful culture of adult human melanocytes from normal and vitiligo donors. J Invest Dermatol 1990;95:441-445
39. Barker D, Dixon K, Medrano EE, Smalara D, Im S, Mitchell D, Babcock G, Abdel-Malek ZA. Comparison of the responses of human melanocytes with different melanin contents to ultraviolet B irradiation. Cancer Res 1995;55:4041-4046
40. Feinberg AP, Vogelstein B. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 1983;132:6-13
41. Im S, Moro O, Peng F, Medrano EE, Cornelius J, Babcock G, Nordlund J, Abdel-Malek Z. Activation of the cAMP pathway by α-melanotropin mediates the response of human melanocytes to UVB light. Cancer Res 1998;58:47-54
42. Solca FF, Chluba-de Tapia J, Iwata K, Eberle AN. B16-G4F mouse melanoma cells: An MSH receptor-deficient cell clone. FEBS Lett 1993;322:177-180
43. Kobayashi N, Nakagawa A, Muramatsu T, Yamashina Y, Shirai T, Hashimoto MW, Ishigaki Y, Ohnishi T, Mori T. Supranuclear melanin caps reduce ultraviolet induced DNA photoproducts in human epidermis. J Invest Dermatol 1998;110:806-810
44. Chakraborty AK, Funasaka Y, Slominski A, Ermak G, Hwang J, Pawelek JM, Ichihashi M. Production and release of proopiomelanocortin (POMC) derived peptides by human melanocytes and keratinocytes in culture: Regulation by ultraviolet B. Biochim Biophys Acta 1996;1313:130-138
45. Wakamatsu K, Graham A, Cook D, Thody AJ. Characterization of ACTH peptides in human skin and their activation of the melanocortin-1 receptor. Pigment Cell Res 1997;10:288-297
46. Suzuki I, Kato T, Motokawa T, Tomita Y, Nakamura E, Katagiri T. Increase of pro-opiomelanocortin mRNA prior to tyrosinase, tyrosinase-related protein 1, dopachrome tautomerase, Pmel-17/gp100, and P-protein mRNA in human skin after ultraviolet B irradiation. J Invest Dermatol 2002;118:73-78
47. Mountjoy KG, Bird IM, Rainey WE, Cone RD. ACTH induces up-regulation of ACTH receptor mRNA in mouse and human adrenocortical cell lines. Mol Cell Endocrinol 1994;99:R17-R20
48. Aberdam E, Bertolotto C, Sviderskaya EV, de Thillot V, Hemesath TJ, Fisher DE, Bennett DC, Ortonne JP, Ballotti R. Involvement of microphthalmia in the inhibition of melanocyte lineage differentiation and of melanogenesis by agouti signal protein. J Biol Chem 1998;273:19560-19565
49. Thody AJ. The MSH Peptides. London, New York: Academic Press; 1980.
50. Bolognia J, Murray M, Pawelek J. UVB-induced melanogenesis may be mediated through the MSH-receptor system. J Invest Dermatol 1989;92:651-656
51. Pawelek JM, Chakraborty AK, Osber MP, Orlow SJ, Min KK, Rosenzweig KE, Bolognia JL. Molecular cascades in UV-induced melanogenesis: A central role for melanotropins? Pigment Cell Res 1992;5:348-356