메뉴 건너뛰기




Volumn 994, Issue , 2003, Pages 359-365

Significance of the melanocortin 1 receptor in regulating human melanocyte pigmentation, proliferation, and survival

Author keywords

Melanocortin 1 receptor; Melanocortins; Melanocytes; Melanoma; Pigmentation; Skin cancer; Ultraviolet radiation

Indexed keywords

AGOUTI RELATED PROTEIN; ALPHA INTERMEDIN; ARGININE; ASPARTIC ACID; BETA INTERMEDIN; CORTICOTROPIN; CYSTEINE; GAMMA INTERMEDIN; HISTIDINE; MELANIN; MELANOCORTIN 1 RECEPTOR; TRYPTOPHAN;

EID: 0037713158     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2003.tb03200.x     Document Type: Conference Paper
Times cited : (126)

References (43)
  • 1
    • 0000550995 scopus 로고
    • α-Melanocyte stimulating hormone: Chemical nature and mechanism of action
    • SAWYER, T.K. et al. 1983. α-Melanocyte stimulating hormone: chemical nature and mechanism of action. Am. Zool. 23: 529-540.
    • (1983) Am. Zool. , vol.23 , pp. 529-540
    • Sawyer, T.K.1
  • 2
    • 0000867959 scopus 로고
    • Melanotropic peptides and receptors: An evolutionary perspective in vertebrate physiologic color change
    • M.E. Hadley, Ed. CRC Press. Boca Raton, FL
    • SHERBROOKE, W.C. et al. 1988. Melanotropic peptides and receptors: an evolutionary perspective in vertebrate physiologic color change. In Melanotropic Peptides. Vol. II. M.E. Hadley, Ed.: 175-190. CRC Press. Boca Raton, FL.
    • (1988) Melanotropic Peptides , vol.2 , pp. 175-190
    • Sherbrooke, W.C.1
  • 3
    • 0015455845 scopus 로고
    • The effect of melanocyte-stimulating hormone on coat color in the mouse
    • GESCHWIND, I.I. et al. 1972. The effect of melanocyte-stimulating hormone on coat color in the mouse. Rec. Prog. Horm. Res. 28: 91-130.
    • (1972) Rec. Prog. Horm. Res. , vol.28 , pp. 91-130
    • Geschwind, I.I.1
  • 4
    • 0021021759 scopus 로고
    • MSH peptides are present in mammalian skin
    • THODY, A.J. et al. 1983. MSH peptides are present in mammalian skin. Peptides 4: 813-816.
    • (1983) Peptides , vol.4 , pp. 813-816
    • Thody, A.J.1
  • 5
    • 0025061965 scopus 로고
    • α-MSH causes a small rise in cAMP but has no effect on basal or ultraviolet-stimulated melanogenesis in human melanocytes
    • FRIEDMAN, P.S. et al. 1990. α-MSH causes a small rise in cAMP but has no effect on basal or ultraviolet-stimulated melanogenesis in human melanocytes. Br. J. Dermatol. 123: 145-151.
    • (1990) Br. J. Dermatol. , vol.123 , pp. 145-151
    • Friedman, P.S.1
  • 6
    • 0027223731 scopus 로고
    • Pigmentation and proliferation of human melanocytes and the effects of melanocyte-stimulating hormone and ultraviolet B light
    • HALABAN, R. et al. 1993. Pigmentation and proliferation of human melanocytes and the effects of melanocyte-stimulating hormone and ultraviolet B light. Ann. N. Y. Acad. Sci. 680: 290-301.
    • (1993) Ann. N. Y. Acad. Sci. , vol.680 , pp. 290-301
    • Halaban, R.1
  • 7
    • 36949078628 scopus 로고
    • Effect of alpha- and beta-melanocyte stimulating hormones on the skin colour of man
    • LERNER, A.B. & J.S. MCGUIRE. 1961. Effect of alpha- and beta-melanocyte stimulating hormones on the skin colour of man. Nature 189: 176-179.
    • (1961) Nature , vol.189 , pp. 176-179
    • Lerner, A.B.1    McGuire, J.S.2
  • 8
    • 0025791976 scopus 로고
    • Induction of skin tanning by the subcutaneous administration of a potent synthetic melanotropin
    • LEVINE, N. et al. 1991. Induction of skin tanning by the subcutaneous administration of a potent synthetic melanotropin. JAMA 266: 2730-2736.
    • (1991) JAMA , vol.266 , pp. 2730-2736
    • Levine, N.1
  • 9
    • 0026800892 scopus 로고
    • The cloning of a family of genes that encode the melanocortin receptors
    • MOUNTJOY, K.G. et al. 1992. The cloning of a family of genes that encode the melanocortin receptors. Science 257: 1248-1251.
    • (1992) Science , vol.257 , pp. 1248-1251
    • Mountjoy, K.G.1
  • 10
    • 0027172312 scopus 로고
    • Molecular cloning of a novel human melanocortin receptor
    • CHHAJLANI, V. et al. 1993. Molecular cloning of a novel human melanocortin receptor. Biochem. Biophys. Res. Commun. 195: 866-873.
    • (1993) Biochem. Biophys. Res. Commun. , vol.195 , pp. 866-873
    • Chhajlani, V.1
  • 11
    • 0001466640 scopus 로고    scopus 로고
    • Production and release of proopiomelanocortin (POMC) derived peptides by human melanocytes and keratinocytes in culture: Regulation by ultraviolet B
    • CHAKRABORTY, A.K. et al. 1996. Production and release of proopiomelanocortin (POMC) derived peptides by human melanocytes and keratinocytes in culture: regulation by ultraviolet B. Biochim. Biophys. Acta 1313: 130-138.
    • (1996) Biochim. Biophys. Acta , vol.1313 , pp. 130-138
    • Chakraborty, A.K.1
  • 12
    • 0031242973 scopus 로고    scopus 로고
    • Characterization of ACTH peptides in human skin and their activation of the melanocortin-1 receptor
    • WAKAMATSU, K. et al. 1997. Characterization of ACTH peptides in human skin and their activation of the melanocortin-1 receptor. Pigm. Cell Res. 10: 288-297.
    • (1997) Pigm. Cell Res. , vol.10 , pp. 288-297
    • Wakamatsu, K.1
  • 13
    • 0028177933 scopus 로고
    • 7α-MSH affect morphology, tyrosinase activity and melanogenesis in cultured human melanocytes
    • 7α-MSH affect morphology, tyrosinase activity and melanogenesis in cultured human melanocytes. J. Cell Sci. 107: 205-211.
    • (1994) J. Cell Sci. , vol.107 , pp. 205-211
    • Hunt, G.1
  • 14
    • 0028920049 scopus 로고
    • Mitogenic and melanogenic stimulation of normal human melanocytes by melanotropic peptides
    • ABDEL-MALEK, Z. et al. 1995. Mitogenic and melanogenic stimulation of normal human melanocytes by melanotropic peptides. Proc. Natl. Acad. Sci. USA 92: 1789-1793.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 1789-1793
    • Abdel-Malek, Z.1
  • 15
    • 0029863304 scopus 로고    scopus 로고
    • Binding capacity and activation of the MC1 receptors by melanotropic hormones correlate directly with their mitogenic and melanogenic effects on human melanocytes
    • SUZUKI, I. et al. 1996. Binding capacity and activation of the MC1 receptors by melanotropic hormones correlate directly with their mitogenic and melanogenic effects on human melanocytes. Endocrinology 137: 1627-1633.
    • (1996) Endocrinology , vol.137 , pp. 1627-1633
    • Suzuki, I.1
  • 16
    • 0003041082 scopus 로고
    • Photobiology of pigment cells
    • M. Seiji, Ed. University of Tokyo Press. Tokyo
    • PATHAK, M.A. et al. 1980. Photobiology of pigment cells. In Phenotypic Expression in Pigment Cells. M. Seiji, Ed.: 655-670. University of Tokyo Press. Tokyo.
    • (1980) Phenotypic Expression in Pigment Cells , pp. 655-670
    • Pathak, M.A.1
  • 17
    • 0028231062 scopus 로고
    • vy/- mice: Ectopic expression of the agouti gene
    • vy/- mice: ectopic expression of the agouti gene. FASEB J. 8: 479-488.
    • (1994) FASEB J. , vol.8 , pp. 479-488
    • Yen, T.T.1
  • 18
    • 0030218918 scopus 로고    scopus 로고
    • The genetics of pigmentation: From fancy genes to complex traits
    • BARSH, G.S. 1996. The genetics of pigmentation: from fancy genes to complex traits. Trends Genet. 12: 299-305.
    • (1996) Trends Genet. , vol.12 , pp. 299-305
    • Barsh, G.S.1
  • 19
    • 0025779123 scopus 로고
    • Pheomelanin as well as eumelanin is present in human epidermis
    • THODY, A.J. et al. 1991. Pheomelanin as well as eumelanin is present in human epidermis. J. Invest. Dermatol. 97: 340-344.
    • (1991) J. Invest. Dermatol. , vol.97 , pp. 340-344
    • Thody, A.J.1
  • 20
    • 0028981255 scopus 로고
    • 7 α-melanocyte-stimulating hormone increases the eumelanin:phaeomelanin ratio in cultured human melanocytes
    • 7 α-melanocyte-stimulating hormone increases the eumelanin:phaeomelanin ratio in cultured human melanocytes. J. Invest. Dermatol. 104: 83-85.
    • (1995) J. Invest. Dermatol. , vol.104 , pp. 83-85
    • Hunt, G.1
  • 21
    • 0027103724 scopus 로고
    • The expression of functional MSH receptors on cultured human melanocytes
    • DONATIEN, P.D. et al. 1992. The expression of functional MSH receptors on cultured human melanocytes. Arch. Dermatol. Res. 284: 424-426.
    • (1992) Arch. Dermatol. Res. , vol.284 , pp. 424-426
    • Donatien, P.D.1
  • 22
    • 0027218913 scopus 로고
    • α-Melanocyte stimulating hormone (αMSH) stimulates normal human melanocyte growth by binding to high-affinity receptors
    • DE LUCA, M. et al. 1993. α-Melanocyte stimulating hormone (αMSH) stimulates normal human melanocyte growth by binding to high-affinity receptors. J. Cell Sci. 105: 1079-1084.
    • (1993) J. Cell Sci. , vol.105 , pp. 1079-1084
    • De Luca, M.1
  • 23
    • 0029831484 scopus 로고    scopus 로고
    • Induction of constitutive melanogenesis in amelanotic mouse melanoma cells by transfection of the human melanocortin-1 receptor gene
    • TAPIA, J.C. et al. 1996. Induction of constitutive melanogenesis in amelanotic mouse melanoma cells by transfection of the human melanocortin-1 receptor gene. J. Cell Sci. 109: 2023-2030.
    • (1996) J. Cell Sci. , vol.109 , pp. 2023-2030
    • Tapia, J.C.1
  • 24
    • 0035504443 scopus 로고    scopus 로고
    • Functional variation of MC1R alleles from red-haired individuals
    • HEALY, E. et al. 2001. Functional variation of MC1R alleles from red-haired individuals. Hum. Mol. Genet. 10: 2397-2402.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 2397-2402
    • Healy, E.1
  • 25
    • 0031838353 scopus 로고    scopus 로고
    • Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans
    • KRUDE, H. et al. 1998. Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans. Nat. Genet. 19: 155-157.
    • (1998) Nat. Genet. , vol.19 , pp. 155-157
    • Krude, H.1
  • 26
    • 0030970586 scopus 로고    scopus 로고
    • Agouti signaling protein inhibits melanogenesis and the response of human melanocytes to α-melanotropin
    • SUZUKI, I. et al. 1997. Agouti signaling protein inhibits melanogenesis and the response of human melanocytes to α-melanotropin. J. Invest. Dermatol. 108: 838-842.
    • (1997) J. Invest. Dermatol. , vol.108 , pp. 838-842
    • Suzuki, I.1
  • 27
    • 0035064572 scopus 로고    scopus 로고
    • The melanocortin 1 receptor is the principal mediator of the effects of agouti signaling protein on mammalian melanocytes
    • ABDEL-MALEK, Z.A. et al. 2001. The melanocortin 1 receptor is the principal mediator of the effects of agouti signaling protein on mammalian melanocytes. J. Cell Sci. 114: 1019-1024.
    • (2001) J. Cell Sci. , vol.114 , pp. 1019-1024
    • Abdel-Malek, Z.A.1
  • 28
    • 18744402160 scopus 로고    scopus 로고
    • Regulation of the human melanocortin 1 receptor expression in epidermal melanocytes by paracrine and endocrine factors, and by UV radiation
    • SCOTT, M.C. et al. 2002. Regulation of the human melanocortin 1 receptor expression in epidermal melanocytes by paracrine and endocrine factors, and by UV radiation. Pigm. Cell Res. 15: 433-439.
    • (2002) Pigm. Cell Res. , vol.15 , pp. 433-439
    • Scott, M.C.1
  • 29
    • 0020624631 scopus 로고
    • Effects of ultraviolet-visible radiation in the presence of melanin isolated from human black or red hair upon Ehrlich ascites carcinoma cells
    • MENON, A. et al. 1983. Effects of ultraviolet-visible radiation in the presence of melanin isolated from human black or red hair upon Ehrlich ascites carcinoma cells. Cancer Res. 43: 3165-3169.
    • (1983) Cancer Res. , vol.43 , pp. 3165-3169
    • Menon, A.1
  • 30
    • 0003157646 scopus 로고
    • The photobiology of melanin pigmentation in human skin
    • T. Kawamura et al., Eds. University Park Press. Baltimore
    • PATHAK, M.A. et al. 1971. The photobiology of melanin pigmentation in human skin. In Biology of Normal and Abnormal Melanocytes. T. Kawamura et al., Eds.: 149-169. University Park Press. Baltimore.
    • (1971) Biology of Normal and Abnormal Melanocytes , pp. 149-169
    • Pathak, M.A.1
  • 31
    • 0020565091 scopus 로고
    • Photocarcinogenesis, skin cancer and aging
    • EPSTEIN, J.H. 1983. Photocarcinogenesis, skin cancer and aging. J. Am. Acad. Dermatol. 9: 487-502.
    • (1983) J. Am. Acad. Dermatol. , vol.9 , pp. 487-502
    • Epstein, J.H.1
  • 32
    • 0026056497 scopus 로고
    • Epidemiology of cutaneous melanoma. An update
    • SOBER, A.J. et al. 1991. Epidemiology of cutaneous melanoma. An update. Dermatol. Clin. 9: 617-629.
    • (1991) Dermatol. Clin. , vol.9 , pp. 617-629
    • Sober, A.J.1
  • 33
    • 0032170736 scopus 로고    scopus 로고
    • Human pigmentation genetics: The difference is only skin deep
    • STURM, R.A. et al. 1998. Human pigmentation genetics: the difference is only skin deep. Bioessays 20: 712-721.
    • (1998) Bioessays , vol.20 , pp. 712-721
    • Sturm, R.A.1
  • 34
    • 7144254441 scopus 로고    scopus 로고
    • Melanocortin 1 receptor variants in Irish population
    • SMITH, R. et al. 1998. Melanocortin 1 receptor variants in Irish population. J. Invest. Dermatol. 111: 119-122.
    • (1998) J. Invest. Dermatol. , vol.111 , pp. 119-122
    • Smith, R.1
  • 35
    • 0030782275 scopus 로고    scopus 로고
    • Characterization of melanocyte stimulating hormone receptor variant alleles in twins with red hair
    • BOX, N.F. et al. 1997. Characterization of melanocyte stimulating hormone receptor variant alleles in twins with red hair. Hum. Mol. Genet. 6: 1891-1897.
    • (1997) Hum. Mol. Genet. , vol.6 , pp. 1891-1897
    • Box, N.F.1
  • 36
    • 0034641860 scopus 로고    scopus 로고
    • Pleiotropic effects of the melanocortin 1 receptor (MC1R) gene on human pigmentation
    • FLANAGAN, N. et al. 2000. Pleiotropic effects of the melanocortin 1 receptor (MC1R) gene on human pigmentation. Hum. Mol. Genet. 9: 2531-2537.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 2531-2537
    • Flanagan, N.1
  • 37
    • 0033910271 scopus 로고    scopus 로고
    • Melanocortin-1 receptor polymorphisms and risk of melanoma: Is the association explained solely by pigmentation phenotype?
    • PALMER, J.S. et al. 2000. Melanocortin-1 receptor polymorphisms and risk of melanoma: is the association explained solely by pigmentation phenotype? Am. J. Hum. Genet. 66: 176-186.
    • (2000) Am. J. Hum. Genet. , vol.66 , pp. 176-186
    • Palmer, J.S.1
  • 38
    • 0035722059 scopus 로고    scopus 로고
    • Melanocortin 1 receptor (MC1R) gene variants are associated with an increased risk for cutaneous melanoma which is largely independent of skin type and hair color
    • KENNEDY, C. et al. 2001. Melanocortin 1 receptor (MC1R) gene variants are associated with an increased risk for cutaneous melanoma which is largely independent of skin type and hair color. J. Invest. Dermatol. 117: 294-300.
    • (2001) J. Invest. Dermatol. , vol.117 , pp. 294-300
    • Kennedy, C.1
  • 39
    • 0035116287 scopus 로고    scopus 로고
    • Melanocortin-1 receptor genotype is a risk factor for basal and squamous cell carcinoma
    • BOX, N.F. et al. 2001. Melanocortin-1 receptor genotype is a risk factor for basal and squamous cell carcinoma. J. Invest. Dermatol. 116: 224-229.
    • (2001) J. Invest. Dermatol. , vol.116 , pp. 224-229
    • Box, N.F.1
  • 40
    • 0035068231 scopus 로고    scopus 로고
    • Melanocortin-1 receptor gene variants determine the risk of non-melanoma skin cancer independent of fair skin type and red hair
    • BASTIAENS, M.T. et al. 2001. Melanocortin-1 receptor gene variants determine the risk of non-melanoma skin cancer independent of fair skin type and red hair. Am. J. Hum. Genet. 68: 884-894.
    • (2001) Am. J. Hum. Genet. , vol.68 , pp. 884-894
    • Bastiaens, M.T.1
  • 41
    • 0036591966 scopus 로고    scopus 로고
    • Human melanocortin 1 receptor variants, receptor function and melanocyte response to ultraviolet radiation
    • SCOTT, M.C. et al. 2002. Human melanocortin 1 receptor variants, receptor function and melanocyte response to ultraviolet radiation. J. Cell Sci. 115: 2349-2355.
    • (2002) J. Cell Sci. , vol.115 , pp. 2349-2355
    • Scott, M.C.1
  • 42
    • 0036144597 scopus 로고    scopus 로고
    • Interleukin-12 suppresses ultraviolet radiation-induced apoptosis by inducing DNA repair
    • SCHWARZ, A. et al. 2002. Interleukin-12 suppresses ultraviolet radiation-induced apoptosis by inducing DNA repair. Nat. Cell Biol. 4: 26-31.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 26-31
    • Schwarz, A.1
  • 43
    • 0037031880 scopus 로고    scopus 로고
    • Insulin-like growth factor-1-mediated AKT activation postpones the onset of ultraviolet B-induced apoptosis, providing more time for cyclobutane thymine dimer removal in primary human keratinocytes
    • DECRAENE, D. et al. 2002. Insulin-like growth factor-1-mediated AKT activation postpones the onset of ultraviolet B-induced apoptosis, providing more time for cyclobutane thymine dimer removal in primary human keratinocytes. J. Biol. Chem. 277: 32587-32595.
    • (2002) J. Biol. Chem. , vol.277 , pp. 32587-32595
    • Decraene, D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.