Animals under the sun: Effects of ultraviolet radiation on mammalian skin

Clinics in Dermatology

Volumn 16, Issue 4, 1998, Pages 503-515

  Slominski, Andrzej ^a,b   Pawelek, John ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HORMONE RECEPTOR; INTERMEDIN;

HUMAN; KERATINOCYTE; NONHUMAN; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; SKIN; SKIN CARCINOGENESIS; SKIN PIGMENTATION; SOLAR RADIATION; SUN EXPOSURE; ULTRAVIOLET RADIATION;

ANIMALS; DISEASE MODELS, ANIMAL; DNA; DNA DAMAGE; EPIDERMIS; HUMANS; KERATINOCYTES; MAMMALS; MELANINS; MELANOCYTE-STIMULATING HORMONES; MELANOCYTES; PHOTORECEPTORS; PRO-OPIOMELANOCORTIN; RECEPTORS, CORTICOTROPIN; RECEPTORS, MELANOCORTIN; SIGNAL TRANSDUCTION; SKIN; SKIN AGING; SKIN PIGMENTATION; SUNLIGHT; ULTRAVIOLET RAYS;

EID: 0032323616     PISSN: 0738081X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0738-081X(98)00023-6     Document Type: Review

References (149)

1. Morison W.L. Phototherapy and photochemotherapy of skin disease. 1991;Raven Press, New York.
2. Fitzpatrick T.B., Eizen A.Z., Wolff K., et al. Dermatology in general medicine. 1993;McGraw-Hill, New York.
3. Goldsmith L.A. Physiology, biochemistry and molecular biology of the skin. 1991;Oxford University Press, New York.
4. Peak M.J., Peak J.G., Carnes B.A. Induction of direct and indirect single-strand breaks in human cell DNA by far- and near-ultraviolet radiations Action spectrum and mechanisms . Photochem Photobiol. 45:1987;381-387.
5. Gilchrest B.A., Park H.-Y., Eller M.S., et al. Mechanisms of ultraviolet light-induced pigmentation. Photochem Photobiol. 63:1996;1-10.
6. Grossman D., Leffel D.J. The molecular basis of nonmelanoma cancer. New understanding. Arch Dermatol. 133:1997;1263-1270.
7. Fisher G.J., Datta S.C., Talwar H.S., et al. Molecular basis of sun-induced premature skin ageing and retinoid antagonism. Nature. 379:1996;335-339.
8. Chase H.B. Growth of the hair. Physiol Rev. 34:1954;113-126.
9. Slominski A., Paus R. Melanogenesis is coupled to murine anagen Toward new concepts for the role of melanocytes and the regulation of melanogenesis in hair growth . J Invest Dermatol. 101:1993;90S-97S.
10. Studzinski G.P., Moore D. Sunlight - can it prevent as well as cause cancer. Cancer Res. 55:1995;4014-4022.
11. Pawelek J., Chakraborty A.K., Osber M.P., et al. Molecular cascade in UV-induced melanogenesis A central role for melanotropins? Pigment Cell Res. 5:1992;348-356.
12. Chakraborty A.K., Orlow S.J., Bolognia J.L., et al. Structural/functional relationship between internal and external MSH receptors Modulation of expression in Cloudman melanoma cells by UVB radiation . J Cell Physiol. 147:1991;1-6.
13. Bolognia J., Murray M., Pawelek J. UVB-induced melanogenesis may be mediated through the MSH-receptor system. J Invest Dermatol. 92:1989;651-656.
14. Chakraborty A., Slominski A., Ermak G., et al. Ultraviolet and melanocyte-stimulating hormone (MSH) stimulate mRNA production of αMSH receptors and proopiomelanocortin-derived peptides in mouse melanoma cells and transformed keratinocytes. J Invest Dermatol. 105:1995;655-659.
15. Chakraborty A., Funasaka Y., Slominski A., et al. Production and release of proopiomelanocortin (POMC) derived peptides by human melanocytes and keratinocytes in culture Regulation by UVB . Biochim Biophys Acta. 1313:1996;130-138.
16. Slominski A., Baker J., Ermak G., et al. UVB stimulates production of corticotropin releasing factor (CRF) by human melanocytes. FEBS Lett. 399:1996;175-176.
17. Mai S., Stein B., Van Den Berg S., et al. Mechanisms of the ultraviolet light response in mammalian cells. J Cell Sci. 94:1989;609-615.
18. Maytin E.V. Heat shock proteins and molecular chaperones Implications for adaptive responses in the skin . J Invest Dermatol. 104:1995;448-455.
19. Eller M.S., Maeda T., Magnoni C., et al. Enhancement of DNA repair in human skin cells by thymidine dinucleotides Evidence for a p53-mediated mammalian SOS response . Proc Natl Acad Sci USA. 94:1997;12627-12632.
20. Robinson J., Schmitt E.A., Harosi F.I., et al. Zebrafish ultraviolet visual pigment Absorption spectrum, sequence and localization . Proc Natl Acad Sci USA. 90:1993;6009-6012.
21. Loew E.R., Govardovskii V.I., Rohlich P., et al. Microspectrophotometric and immunocytochemical identification of ultraviolet photoreceptors in geckos. Visual Neurosci. 13:1996;247-256.
22. Placios A.G., Goldsmith T.H., Bernard G.D. Sensitivity of cones from cyprinind fish (Danio aequipinnatus) to ultraviolet and visible light. Visual Neurosci. 13:1996;411-421.
23. Raymond P.A., Barthel L.K., Stenkamp D.L. The zebrafish ultraviolet cone opsin reported previously is expressed in rods. Invest Ophthalmol Visual Sci. 37:1996;948-950.
24. Towner P., Harris P., Wolstenholme A.J., et al. Primary structure of locust opsin A speculative model which may account for ultraviolet wavelength light detection . Vision Res. 37:1997;495-503.
25. Sillman A.J., Govardovskii Rohlich P., Soithard J.A., et al. The photoreceptors and visual pigments of the garter snake (Thamnophis sirtalis) A microspectrophotometric, scanning electron microscopic and immunocytochemical study . J Comp Physiol. 181:1997;89-101.
26. Bennet A.T., Cuthill I.C., Partridge J.C., et al. Ultraviolet plumage colors predict mate preferences in starlings. Proc Natl Acad Sci USA. 94:1997;8618-8621.
27. Kawamura S., Yokoyama S. Functional characterization of visual and nonvisual pigments of american chameleon (Anolis carolinensis). Vision Res. 38:1997;37-44.
28. Vonschantz M., Argamasoherman S.M., Szel A., et al. Photopigments and photoentrainment in the Syrian golden hamsters. Brain Res. 770:1997;131-138.
29. Bertagna X., Lenne F., Comar D., et al. Human β-melanocyte-stimulating hormone revisited. Proc Natl Acad Sci USA. 83:1986;9719-9723.
30. Allen B.M. The results of extirpation of the anterior lobe of the hypophysis and of the thyroid of Rana pipiens larvae. Science. 49:1916;755-758.
31. Atwell W.J. On the nature of the pigmentation changes following hypophysectomy in the frog larva. Science. 49:1916;48-50.
32. Inoue A., Kita T., Nakomura M., et al. Nucleotide sequence of cloned cDNA for bovine corticotropin-β-lipotropin precursor. Nature. 278:1979;423-427.
33. Kock A., Schauer E., Schwarz T., et al. MSH and ACTH production by human keratinocytes A link between the neuronal and the immune system . J Invest Dermatol. 94:1990;543A.
34. Slominski A., Paus R., Mazurkiewicz J. Proopiomelanocortin expression in the skin during induced hair growth in mice. Experientia. 48:1992;50-54.
35. Mountjoy K.G., Robins L.S., Mortrud M.T., et al. The cloning of a family of genes that encode the melanocortin receptors. Science. 257:1992;1248-1251.
36. Lerner A.B., McGuire J.S. Effect of alpha- and beta-melanocyte stimulating hormones on the skin color of man. Nature. 189:1961;176-179.
37. Levine N., Sheftel S.N., Eytan T., et al. Induction of skin tanning by subcutaneous administration of a potent synthetic melanotropin. JAMA. 266:1991;2730-2736.
38. Freinkel RK, Freinkel N. Cutaneous manifestation of endocrine disorders. In: Fitzpatrick TB, AZ Eisen AZ, Wolff K, Freedberg IM, Austen KF, editors. Dermatology in general medicine. New York: McGraw-Hill International Book Co, 1987, 2063-81.
39. Bolognia J., Murray M., Pawelek J. UVB-induced melanogenesis may be mediated through the MSH receptor system. J Invest Dermatol. 92:1989;651-656.
40. Chakraborty A.K. MSH receptors in immortalized human epidermal keratinocytes A potential mechanism for coordinate regulation of the epidermal-melanin unit . J Cell Physiol. 157:1993;344-350.
41. Holzmann H., Altmeyer P., Stohr L., et al. Die Beeinfussung des alpha-MSH durch UVA-Bestrahlunger der Haut-ein Funktionstest. Hautarzt. 34:1983;294-297.
42. Holzmann H., Altmeyer P., Schultz-Amling W. Der Einfluss ultravioletter Strtahlen auf die Hypothalamus- Hypophysenachse des Menschen. Act Dermatol. 8:1982;119-123.
43. Wakamatsu K., Graham A., Cook D., et al. Characterisation of ACTH peptides in human skin and their activation of the melanocortin-1 receptor. Pigment Cell Res. 10:1997;288-297.
44. Wikswo M.A. Action of cyclic AMP on pigment donation between mammalian melanocytes and keratinocytes. Yale J Biol Med. 46:1973;592-601.
45. Klaus S.N. Pigment transfer in mammalian epidermis. Arch Dermatol. 100:1969;756-762.
46. Wolff K. Melanocyte/keratinocyte interactions in vivo The fate of melanosomes . Yale J Biol Med. 46:1973;384-396.
47. Kupper T.S., Chua A.O., Flood P., et al. Interleukin 1 gene expression in cultured human keratinocytes is augmented by ultraviolet irradiation. J Clin Invest. 80:1987;430-436.
48. Gordon P.R., Mansur C.P., Gilchrest B.A. Regulation of human melanocyte growth, dendricity, and melanization by keratinocyte derived factors. J Invest Dermatol. 92:1989;565-572.
49. Halaban R.R., Langdon R., Birchall N., et al. Basic fibroblast growth factor from human keratinocytes is a natural mitogen for melanocytes. J Cell Biol. 107:1988;1611-1619.
50. Birchall N., Orlow S.J., Kupper T., et al. Interactions between ultraviolet light and interleukin-1 on MSH binding in both mouse melanoma and human squamous carcinoma cells. Bioch Biophys Res Comm. 175:1991;839-845.
51. Kirnbauer R., Charvat B., Schauer E., et al. Modulation of intercellular adhesion molecule-1 expression on human melanocytes and melanoma cells Evidence for a regulatory role of IL-6, IL-7, TNFβ, and UVB light . J Invest Dermatol. 98:1992;320-326.
52. Urbanski A., Schwarz T., Neuner P., et al. Ultraviolet light induces increased circulating interleukin-6 in humans. J Invest Dermatol. 94:1990;808-811.
53. Min K., Pawelek J. Identification and characterization of β-MSH receptors on transformed human keratinocytes. Yale J Biol Med. 65:1992;369.
54. Orlow S.J., Hotchkiss S., Pawelek J. Internal binding sites for MSH in wild type and variant Cloudman melanoma cells. J Cell Physiol. 142:1990;129-136.
55. Slominski A., Paus R., Wortsman J. Can some melanotropins modulate keratinocyte proliferation? J Invest Dermatol. 97:1991;747.
56. Holick M.F., MacLaughlin J.A., Clark M.D., et al. Photosynthesis of previtamin D3 in human skin and the physiologic consequences. Science. 210:1980;203-205.
57. Kripke M.L. Ultraviolet radiation and immunology Something new under the sun . Cancer Res. 54:1994;6102-6105.
58. Selgrade M.J.K., Repacholi M.H., Koren H.S. Ultraviolet radiation-induced immune modulation Potential consequences for infectious, allergic, and autoimmune disease . Environment Health Pers. 105:1997;332-334.
59. Bos J.D. Skin immune system (SIS). 1997;CRC Press Inc, Boca Raton FL.
60. Slominski A. Correspondence re GP Studzinski and DC Moore, Sunlight - can it prevent as well as cause cancer? Cancer Res. 56:1996;925.
61. Slominski A., Mihm M. On a potential mechanism of skin response to stress. Int J Dermatol. 35:1996;849-851.
62. Gangi S., Johansson O. Skin changes in "screen dermatitis" versus classical UV- and ionizing irradiation-related damage - similarities and differences. Two neuroscientists' speculative review. Exp Dermatol. 6:1997;283-291.
63. Prota G. Melanins and melanogenesis. 1992;1-290 Academic Press, New York.
64. Prota G. Pigment cell research What directions? Pigment Cell Res. 10:1997;5-11.
65. Hori Y., Hearing V.J., Nakayama J. Melanogenesis and malignant melanoma Biochemistry, cell biology, molecular biology, pathophysiology, diagnosis and treatment . 1996;Elsevier, New York.
66. Pawelek J. After dopachrome? Pigment Cell Res. 4:1991;53-62.
67. Thody A.J. Epidermal melanocytes Their regulation and role in skin pigmentation . Eur J Dermatol. 5:1995;558-565.
68. Slominski A., Paus R., Schanderdorf D. Melanocytes as sensory and regulatory cells in the epidermis. J Theor Biol. 164:1993;103-120.
69. Nordlund J.J., Boissy R., Hearing V., King R., Ortonne J.-P. The pigmentary system. 1998;Oxford University Press, New York.
70. Eller M.S., Ostrom K., Gilchrest B. DNA enhances melanogenesis. Proc Natl Acad Sci USA. 93:1996;1087-1092.
71. DeLeo V.A., Horlick H., Hanson D., et al. Ultraviolet radiation induces changes in membrane metabolism of human keratinocytes in culture. J Invest Dermatol. 83:1984;323-326.
72. Sondergaard J., Bisgaard H., Thorsen S. Eicosanoids in skin UV inflammation. Photodermatology. 2:1985;359-366.
73. Carsberg C.J., Ohanian J., Friedmann P.S. Ultraviolet radiation stimulates a biphasic pattern of 1,2-diaglycerol formation in cultured human melanocytes and keratinocytes by activation of phospholipase C and D. Biochem J. 305:1995;471-477.
74. Schauer E., Trautinger F., Kock A., et al. Proopiomelanocortin-derived peptides are synthesized and released by human keratinocytes. J Clin Invest. 93:1994;2258-2262.
75. Winzen M., Yaar M., Burbach J.P.H., et al. Proopiomelanocortin gene product regulation in keratinocytes. J Invest Dermatol. 106:1996;673-678.
76. Slominski A., Paus R., Wortsman J. On the potential role of proopiomelanocortin in skin physiology and pathology. Mol Cell Endocrinol. 93:1993;C1-C6.
77. Im S., Moro O., Peng F., et al. Activation of the cyclic AMP pathway by α-melanotropin mediates the response of human melanocytes to ultraviolet B radiation. Cancer Res. 58:1998;47-54.
78. Imokawa G., Yada Y., Kimura M. Signalling mechanisms of endothelin-induced mitogenesis and melanogenesis in human melanocytes. Biochem J. 314:1996;305-312.
79. Levine N., Sheftel S.N., Eytan T., et al. Induction of skin tanning by subcutaneous administration of a potent synthetic melanotropin. JAMA. 266:1991;2730-2736.
80. Eller M.S., Yaar M., Gilchrest B.A. DNA damage and melanogenesis. Nature. 372:1994;413-414.
81. Kripke M.L. Effects of UV radiation on tumor immunity. J Natl Cancer Inst. 82:1990;1392-1396.
82. De Fabo E.C., Noonan F.P. Mechanism of immune suppression by ultraviolet irradiation in vivo I. Evidence for the existence of a unique photoreceptor in skin and its role in photoimmunology . J Exp Med. 158:1983;84-98.
83. Webber L.J., Whang E., De Fabo E.C. The effects of UVA-I (340-400 nm), UVA-II (320-340 nm) and UVA-I+II on the photoisomerization of urocanic acid in vivo. Photochem Photobiol. 66:1997;484-492.
84. Moodycliffe A.M., Bucana C.D., Kripke M.L., et al. Differential effects of a monoclonal antibody to cis-urocanic acid on the suppression of delayed and contact hypersensitivity following ultraviolet irradiation. J Immunol. 157:1996;2891-2899.
85. Luger TA, Scholzen T, Brzoska T, et al. Cutaneous immunomodulation and coordination of skin stress responses by alpha-melanocyte-stimulating hormone. Ann NY Acad Sci 1998; in press.
86. Ko C.B., Walton S., Keczkes K., et al. The emerging epidemic of skin cancer. Br J Dermatol. 130:1994;269-272.
87. Urbach F. Ultraviolet radiation and skin cancers in humans. J Photochem Photobiol, B-Biol. 40:1997;3-7.
88. Nomura T., Nakajima H., Hongyom T., et al. Inductions of cancer, actinic keratosis, and specific p53 mutations by UVB light in human skin maintained in severe combined immunodeficient mice. Cancer Res. 57:1997;2081-2084.
89. Gailini M.R., Leffel D.J., Ziegler A.M., et al. Relationship between sunlight exposure and a key genetic alteration in basal cell carcinoma. J Natl Cancer Inst. 88:1996;349-354.
90. Kusewitz D.F., Applegate L.A., Ley R.D. Ultraviolet radiation-induced skin tumors in South American opossum (Monodelphis domestica). Vet Pathol. 28:1991;55-65.
91. Robinson E.S., VandeBerg J.L., Hubbard G.B., et al. Malignant melanoma in ultraviolet irradiated opossum Initiation in suckling young, metastasis in adults, and xenograft behavior in nude mice . Cancer Res. 54:1994;5986-5991.
92. Ley R.D. Ultraviolet radiation A-induced precursors of cutaneous melanoma in Monodelphis domestica. Cancer Res. 57:1997;3682-3684.
93. Menzies S.W., Greenoak G.E., Reeve V.E., et al. Ultraviolet radiation-induced murine tumors produced in the absence of ultraviolet radiation-induced systemic tumor immunosuppression. Cancer Res. 51:1991;2773-2779.
94. Kleint-Szanto A.J.P., Silvers W.S., Mintz B. Ultraviolet radiation-induced malignant skin melanoma in melanoma-susceptible transgenic mice. Cancer Res. 54:1994;4569-4572.
95. Ueda M., Ouhtit A., Bito T., et al. Evidence for UV-associated activation of telomerase in human skin. Cancer Res. 57:1997;370-374.
96. Bishop J.A.N. Molecular pathology of melanoma. Cancer Met Rev. 16:1997;141-154.
97. Kang S., Fisher G.J., Voorhees J.J. Photoaging and topical tretinoin. Arch Dermatol. 133:1997;1280-1284.
98. Castanet J., Ortonne J.-P. Pigmentary changes in aged and photoaged skin. Arch Dermatol. 133:1997;1296-1299.
99. Mozolowski W. Jedrzej Sniadecki on the cure of rickets. Nature. 143:1939;121.
100. Tian X.Q., Chen T.C., Matsuoka L.Y., et al. Kinetic and thermodynamic studies of the conversion of previtamin D3 to vitamin D3 in human skin. J Biol Chem. 268:1993;14888-14892.
101. Webb A.R., Holick M.F. The role of sunlight in the cutaneous production of vitamin D3. Annu Rev Nutr. 8:1988;375-399.
102. Walters M.R. Newly identified actions of the vitamin D endocrine system. Endocrine Rev. 13:1992;719-764.
103. Feling P., Baxter J.D., Frohman L.A. Endocrinology and metabolism. Third edition. 1995;McGraw-Hill, New York.
104. Ghanem G., Verstegen J., DeRijcke, et al. Studies of factors influencing human plasma α-MSH. Anticancer Res. 9:1989;1691-1696.
105. Rosette C., Karin M. Ultraviolet light and osmostic stress Activation of the JNK cascade through multiple growth factor and cytokine receptors . Science. 274:1996;1194-1197.
106. Devary Y., Rosetter C., DiDonato J.A., et al. NF-kB activation by ultraviolet light not dependent on a nuclear signal. Science. 261:1993;1442-1445.
107. Basu-Modal S., Tyrrell R.M. Singlet oxygen A primary effector in the ultravioletA/near-visible light induction of the human heme oxygenase gene . Cancer Res. 53:1993;4505-4510.
108. Devary Y., Gottlieb R.A., Smeal T., et al. The mammalian ultraviolet response is triggered by activation of src tyrosine kinases. Cell. 71:1992;1081-1091.
109. Warmuth Harth Y., Matsui M.S., et al. Ultraviolet radiation induces phosphorylation of the epidermal growth factor receptor. Cancer Res. 54:1994;374-376.
110. Hilgers G., Clauss I.M., Huez G.A., et al. Post-transcriptional effect of ultraviolet light on gene expression in human cells. Stabilization of cytokine-induced and poly(I).poly(A)-induced messenger RNA. Eur J Biochem. 201:1991;483-488.
111. Conconi A., Smerdon M.J., Howe G.A., et al. The octadecanoid signalling pathway in plants mediates a response to ultraviolet radiation. Science. 383:1996;826-829.
112. Price M.A., Cruzalegui F.H., Treisman R. The p38 and ERKMAP kinase pathways cooperate to activate ternary complex factors and c-fos transcription in response to UV light. EMBO J. 15:1966;6552-6563.
113. Liu Z.-G., Baskaran R., Lea-Chou E.T., et al. Three distinct signalling responses by murine fibroblasts to genotoxic stress. Nature. 384:1996;273-276.
114. Ortin V.R., McLenigan M., Takao M., et al. Translocation of a UV-damaged binding protein into a tight association with chromatin after treatment of mammalian cells with UV light. J Cell Sci. 110:1997;1159-1168.
115. Ronai Z., Rutberg S., Yang Y.M. UV-responsive element (TGACAACA) from rat fibroblasts to human melanomas. Env Mol Mutagenesis. 23:1994;157-163.
116. Hanson D.L., DeLeo V.A. Longwave ultraviolet radiation stimulates arachidonic acid release and cyclooxygenase activity in mammalian cells in culture. Photochem Photobiol. 49:1989;423-430.
117. DeLeo V., Schleide S., Meshulam J., et al. Ultraviolet radiation alters choline phospholipid metabolism in human keratinocytes. J Invest Dermatol. 91:1988;303-308.
118. Matsui M.S., DeLeo V. Induction of protein kinase C activity by ultraviolet radiation. Clin Carcinogen. 11:1990;229-234.
119. Romero-Graillet C., Aberdam E., Biagoli N., et al. Ultraviolet B radiation acts through the nitric oxide and cGMP signal transduction pathway to stimulate melanogenesis in human melanocytes. J Biol Chem. 271:1996;28052-28056.
120. Romero-Graillet C., Aberdam E., Clement M., et al. Nitric oxide produced by ultraviolet-irradiated keratinocytes stimulates melanogenesis. J Clin Invest. 99:1997;635-642.
121. Pawelek J., Bolognia J., McLane J., et al. A possible role of melanin precursors in regulating both pigmentation and proliferation of melanocytes. Adv Pigment Res Prog Clin Biol Res. 256:1988;143-155.
122. Slominski A., Paus R. Are L-tyrosine and L-dopa hormone-like bioregulators. J Theor Biol. 143:1990;123-138.
123. Slominski A., Paus R. Towards defining receptors for L-tyrosine and L-DOPA. Molec Cell Endocrinol. 99:1994;C7-C11.
124. Memoli S., Napolitano A., d'Ischia M., et al. Diffusible melanin-related metabolites are potent inhibitors of lipid peroxidation. Biochim Biophys Acta. 1346:1997;61-68.
125. Tsuboi R., Sato C., Oshita Y., et al. Ultraviolet B irradiation increases endothelin-1 and endothelin receptor expression in culture human keratinocytes. FEBS Lett. 371:1995;188-190.
126. Vamvakopoulos N.C., Chrousos G.P. Hormonal regulation of human corticotropin-releasing hormone gene expression Implications for the stress response and immune/inflammatory reaction . Endocrine Rev. 15:1994;409-420.
127. Koch B., Lutz-Bucher B. Inhibition of protein kinase C activity in cultured pituitary cells attenuates both cyclic AMP-independent and -dependent secretion of ACTH. Mol Cell Endocrinol. 77:1991;57-65.
128. Turnbull A.V., River C. Corticotropin-releasing factor, vasopressin, and prostaglandins mediate, and nitric oxide restrains, the hypothalamic-pituitary-adrenal response to acute local inflammation in the rat. Endocrinology. 137:1996;455-463.
129. Nye E.J., Hockings G.I., Grice J.E., et al. Aspirin inhibits vasopressin-induced hypothalamic-pituitary-adrenal activity in normal humans. J Clin Endocrinol Metab. 82:1997;812-817.
130. Grossman A., Costa A., Forsling M.L., et al. Gaseous neurotransmitters in the hypothalamus. The role of nitric oxide and carbon monoxide in neuroendocrinology. Horm Metab Res. 29:1997;477-482.
131. Slominski A., Ermak Hwang J., et al. Proopiomelanocortin, corticotropin releasing hormone and corticotropin releasing hormone receptor genes are expressed in human skin. FEBS Lett. 374:1995;113-116.
132. Slominski A., Ermak G., Mihm M. ACTH receptor, CYP11A1, CYP17 and CYP21A2 genes are expressed in skin. J Clin Endocrinol Met. 81:1996;2746-2749.
133. Slominski A., Ermak Hwang J., et al. The expression of proopiomelanocortin (POMC) and of corticotropin releasing hormone receptor (CRH-R) genes in mouse skin. Biochim Biophys Acta. 1289:1996;247-251.
134. Roloff B., Fechner K., Slominski A., et al. Hair cycle-dependent expression of corticotropin releasing hormone (CRH) and CRH receptors (CRH-R) in murine skin. FASEB J. 12:1998;287-297.
135. Slominski A., Ermak G., Mazurkiewicz J.E., et al. Characterization of corticotropin releasing hormone (CRH) in human skin. J Clin Endocrinol Metab. 83:1998;1020-1024.
136. Theoharides T.C., Singh L.K., Boucher W., et al. Corticotropin-releasing hormone induces skin mast cell degranulation and increased vascular permeability, a possible explanation for its proinflammatory effects. Endocrinology. 139:1988;403-413.
137. Chakraborty A., Pawelek J. MSH receptors in immortalized human epidermal keratinocytes A potential mechanism for coordinated regulation of the epidermal-melanin unit . J Cell Physiol. 157:1993;344-350.
138. Boston B.A., Cone R.D. Characterization of melanocortin receptor subtype expression in murine adipose tissues and in the 3T3-L1 cell line. Endocrinology. 137:1996;2043-2050.
139. Lipton J.M., Catania A. Anti-inflammatory actions of the neuro-immunomodulator α-MSH. Immunol Today. 18:1997;140-145.
140. Slominski A., Paus R. Inhibition of melanogenesis for melanoma therapy? Letter to editor J Invest Dermatol. 103:1995;742.
141. Stryer L. Visual excitation and recovery. J Biol Chem. 266:1991;10711-10714.
142. Lolley R.N., Lee R.H. Cyclic GMP and photoreceptor function. FASEB J. 4:1990;3001-3008.
143. Hargrave P.A., McDowell J.H. Rhodopsin and phototransduction A model system for G protein-linked receptors . FASEB J. 6:1992;2323-2331.
144. Khorana H.G. Bacteriorhodopsin, a membrane protein that uses light to translocate protons. J Biol Chem. 263:1988;7439-7442.
145. Spudich J.L. Protein-protein interaction converts a proton pump into a sensory receptor. Cell. 79:1994;747-750.
146. Freidberg E.C., Walker G.C., Siede W. Repair and mutagenesis. 1995;ASM Press, Washington, DC.
147. Todo T., Ryo H., Yamamoto K., et al. Similarity among the Drosophila (6-4) photolyase a human photolyase homolog, and the DNA photolyase-blue-light photoreceptor family. Science. 272:1996;109-112.
148. Jones A.M. Surprising signals in plant cells. Science. 263:1994;183-184.
149. Tributsch H., Pohlmann L. Synergistic mechanisms in energy and signal transduction Photo oscillating proton transport in bacteriorhodopsin . J Theor Biol. 178:1996;17-28.