메뉴 건너뛰기




Volumn 67, Issue 6, 2007, Pages 2430-2438

Dominant-negative activator protein 1 (TAM67) targets cyclooxygenase-2 and osteopontin under conditions in which it specifically inhibits tumorigenesis

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; CYCLOOXYGENASE 2; DIMETHYLBENZ[A]ANTHRACENE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OSTEOPONTIN; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN C JUN; PROTEIN E7; PROTEIN FOS; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR RELA; TUMOR PROMOTER;

EID: 34047264014     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-06-0522     Document Type: Article
Times cited : (41)

References (46)
  • 1
    • 14044272833 scopus 로고    scopus 로고
    • Estrogen contributes to the onset, persistence, and malignant progression of cervical cancer in a human papillomavirus-transgenic mouse model
    • Brake T, Lambert PF. Estrogen contributes to the onset, persistence, and malignant progression of cervical cancer in a human papillomavirus-transgenic mouse model. Proc Natl Acad Sci U S A 2005;102:2490-5.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 2490-2495
    • Brake, T.1    Lambert, P.F.2
  • 2
    • 0042440926 scopus 로고    scopus 로고
    • Dissection of human papillomavirus E6 and E7 function in transgenic mouse models of cervical carcinogenesis
    • Riley RR, Duensing S, Brake T, Munger K, Lambert PF, Arbeit JM. Dissection of human papillomavirus E6 and E7 function in transgenic mouse models of cervical carcinogenesis. Cancer Res 2003;63:4862-71.
    • (2003) Cancer Res , vol.63 , pp. 4862-4871
    • Riley, R.R.1    Duensing, S.2    Brake, T.3    Munger, K.4    Lambert, P.F.5    Arbeit, J.M.6
  • 3
    • 0034652546 scopus 로고    scopus 로고
    • Human papillomavirus types 16 E6 and E7 contribute differently to carcinogenesis
    • Song S, Liem A, Miller JA, Lambert PF. Human papillomavirus types 16 E6 and E7 contribute differently to carcinogenesis. Virology 2000;267:141-50.
    • (2000) Virology , vol.267 , pp. 141-150
    • Song, S.1    Liem, A.2    Miller, J.A.3    Lambert, P.F.4
  • 4
    • 0024362088 scopus 로고    scopus 로고
    • Bernstein LR, Colburn NH. AP1/jun function is differentially induced in promotion-sensitive and resistant JB6 cells. Science 1989;244:566-9.
    • Bernstein LR, Colburn NH. AP1/jun function is differentially induced in promotion-sensitive and resistant JB6 cells. Science 1989;244:566-9.
  • 5
    • 0028079661 scopus 로고
    • Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells
    • Dong Z, Birrer MJ, Watts RG, Matrisian LM, Colburn NH. Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells. Proc Natl Acad Sci U S A 1994;91:609-13.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 609-613
    • Dong, Z.1    Birrer, M.J.2    Watts, R.G.3    Matrisian, L.M.4    Colburn, N.H.5
  • 6
    • 0032575007 scopus 로고    scopus 로고
    • Expression of dominant negative Jun inhibits elevated AP-1 and NF-κB transactivation and suppresses anchor-age independent growth of HPV immortalized human keratinocytes
    • Li JJ, Rhim JS, Schlegel R, Vousden KH, Colburn NH. Expression of dominant negative Jun inhibits elevated AP-1 and NF-κB transactivation and suppresses anchor-age independent growth of HPV immortalized human keratinocytes. Oncogene 1998;16:2711-21.
    • (1998) Oncogene , vol.16 , pp. 2711-2721
    • Li, J.J.1    Rhim, J.S.2    Schlegel, R.3    Vousden, K.H.4    Colburn, N.H.5
  • 7
    • 0033578305 scopus 로고    scopus 로고
    • Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion
    • Young MR, Li JJ, Rincon M, et al. Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion. Proc Natl Acad Sci USA 1999;96:9827-32.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 9827-9832
    • Young, M.R.1    Li, J.J.2    Rincon, M.3
  • 8
    • 0033646833 scopus 로고    scopus 로고
    • Induced expression of dominant-negative c-Jun down-regulates NFκB and AP-1 target genes and suppresses tumor phenotype in human keratinocytes
    • Li JJ, Cao Y, Young MR, Colburn NH. Induced expression of dominant-negative c-Jun down-regulates NFκB and AP-1 target genes and suppresses tumor phenotype in human keratinocytes. Mol Carcinog 2000; 29:159-69.
    • (2000) Mol Carcinog , vol.29 , pp. 159-169
    • Li, J.J.1    Cao, Y.2    Young, M.R.3    Colburn, N.H.4
  • 9
    • 0036275075 scopus 로고    scopus 로고
    • Protection against human papillomavirus type 16-E7 oncogene-induced tumorigenesis by in vivo expression of dominant-negative c-Jun
    • Young MR, Farrell L, Lambert P, Awasthi P, Colburn NH. Protection against human papillomavirus type 16-E7 oncogene-induced tumorigenesis by in vivo expression of dominant-negative c-Jun. Mol Carcinog 2002;34:72-7.
    • (2002) Mol Carcinog , vol.34 , pp. 72-77
    • Young, M.R.1    Farrell, L.2    Lambert, P.3    Awasthi, P.4    Colburn, N.H.5
  • 10
    • 0027956852 scopus 로고
    • Stable expression of a c-Jun deletion mutant in two malignant mouse epidermal cell lines blocks tumor formation in nude mice
    • Domann FE, Levy JP, Birrer MJ, Bowden GT. Stable expression of a c-Jun deletion mutant in two malignant mouse epidermal cell lines blocks tumor formation in nude mice. Cell Growth Differ 1994;5:9-16.
    • (1994) Cell Growth Differ , vol.5 , pp. 9-16
    • Domann, F.E.1    Levy, J.P.2    Birrer, M.J.3    Bowden, G.T.4
  • 11
    • 0027996872 scopus 로고
    • Fos-transformation activates genes associated with invasion
    • Hennigan RF, Hawker KL, Ozanne BW. Fos-transformation activates genes associated with invasion. Oncogene 1994;9:3591-600.
    • (1994) Oncogene , vol.9 , pp. 3591-3600
    • Hennigan, R.F.1    Hawker, K.L.2    Ozanne, B.W.3
  • 12
    • 0031053311 scopus 로고    scopus 로고
    • AP-1-mediated invasion requires increased expression of the hyaluronan receptor CD44
    • Lamb RF, Hennigan RF, Turnbull K, et al. AP-1-mediated invasion requires increased expression of the hyaluronan receptor CD44. Mol Cell Biol 1997;17:963-76.
    • (1997) Mol Cell Biol , vol.17 , pp. 963-976
    • Lamb, R.F.1    Hennigan, R.F.2    Turnbull, K.3
  • 13
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-κB in cancer development and progression
    • Karin M. Nuclear factor-κB in cancer development and progression. Nature 2006;441:431-6.
    • (2006) Nature , vol.441 , pp. 431-436
    • Karin, M.1
  • 14
    • 0027242180 scopus 로고
    • c-Jun is essential for normal mouse development and hepatogenesis
    • Hilberg F, Aguzzi A, Howells N, Wagner EF. c-Jun is essential for normal mouse development and hepatogenesis. Nature 1993;365:179-81.
    • (1993) Nature , vol.365 , pp. 179-181
    • Hilberg, F.1    Aguzzi, A.2    Howells, N.3    Wagner, E.F.4
  • 15
    • 0027219303 scopus 로고
    • A null mutation at the c-Jun locus causes embryonic lethality and retarded cell growth in culture
    • Johnson RS, van Lingen B, Papaioannou VE, Spiegelman BM. A null mutation at the c-Jun locus causes embryonic lethality and retarded cell growth in culture. Genes Dev 1993;7:1309-17.
    • (1993) Genes Dev , vol.7 , pp. 1309-1317
    • Johnson, R.S.1    van Lingen, B.2    Papaioannou, V.E.3    Spiegelman, B.M.4
  • 16
    • 33645862566 scopus 로고    scopus 로고
    • Jun signalling in the epidermis: From developmental defects to psoriasis and skin tumors
    • Zenz R, Wagner EF. Jun signalling in the epidermis: From developmental defects to psoriasis and skin tumors. Int J Biochem Cell Biol 2006;38:1043-9.
    • (2006) Int J Biochem Cell Biol , vol.38 , pp. 1043-1049
    • Zenz, R.1    Wagner, E.F.2
  • 17
    • 0027410854 scopus 로고
    • Suppression of oncogene-induced transformation by a deletion mutant of c-Jun
    • Brown PH, Alani R, Preis LH, Szabo E, Birrer MJ. Suppression of oncogene-induced transformation by a deletion mutant of c-Jun Oncogene 1993;8:877-86.
    • (1993) Oncogene , vol.8 , pp. 877-886
    • Brown, P.H.1    Alani, R.2    Preis, L.H.3    Szabo, E.4    Birrer, M.J.5
  • 18
    • 0030749569 scopus 로고    scopus 로고
    • A dominant negative mutant of jun blocking 12-O-tetradecanoylphorbol-13-acetate-induced invasion in mouse keratinocytes
    • Dong Z, Crawford HC, Lavrovsky V, et al. A dominant negative mutant of jun blocking 12-O-tetradecanoylphorbol-13-acetate-induced invasion in mouse keratinocytes. Mol Carcinog 1997;19:204-12.
    • (1997) Mol Carcinog , vol.19 , pp. 204-212
    • Dong, Z.1    Crawford, H.C.2    Lavrovsky, V.3
  • 19
    • 28444431942 scopus 로고    scopus 로고
    • Human papillomavirus and disease mechanisms: Relevance to oral and cervical cancers
    • Nair S, Pillai MR. Human papillomavirus and disease mechanisms: relevance to oral and cervical cancers. Oral Dis 2005;11:350-9.
    • (2005) Oral Dis , vol.11 , pp. 350-359
    • Nair, S.1    Pillai, M.R.2
  • 21
    • 0028172914 scopus 로고
    • Disruption of Iκ Bα regulation by antisense RNA expression leads to malignant transformation
    • Beauparlant P, Kwan I, Bitar R, et al. Disruption of Iκ Bα regulation by antisense RNA expression leads to malignant transformation. Oncogene 1994;9:3189-97.
    • (1994) Oncogene , vol.9 , pp. 3189-3197
    • Beauparlant, P.1    Kwan, I.2    Bitar, R.3
  • 22
    • 0027058137 scopus 로고
    • Ablation of transplanted HTLV-I Tax-transformed tumors in mice by antisense inhibition of NF-κB
    • Kitajima I, Shinohara T, Bilakovics J, Brown DA, Xu X, Nerenberg M. Ablation of transplanted HTLV-I Tax-transformed tumors in mice by antisense inhibition of NF-κB. Science 1992;258:1792-5.
    • (1992) Science , vol.258 , pp. 1792-1795
    • Kitajima, I.1    Shinohara, T.2    Bilakovics, J.3    Brown, D.A.4    Xu, X.5    Nerenberg, M.6
  • 23
    • 1542328234 scopus 로고    scopus 로고
    • The IKK/NF-κB activation pathway - a target for prevention and treatment of cancer
    • Greten FR, Karin M. The IKK/NF-κB activation pathway - a target for prevention and treatment of cancer. Cancer Lett 2004;206:193-9.
    • (2004) Cancer Lett , vol.206 , pp. 193-199
    • Greten, F.R.1    Karin, M.2
  • 24
    • 0030064068 scopus 로고    scopus 로고
    • Squamous epithelial hyperplasia and carcinoma in mice transgenic for the human papillomavirus type 16 E7 oncogene
    • Herber R, Liem A, Pitot H, Lambert PF. Squamous epithelial hyperplasia and carcinoma in mice transgenic for the human papillomavirus type 16 E7 oncogene. J Virol 1996;70:1873-81.
    • (1996) J Virol , vol.70 , pp. 1873-1881
    • Herber, R.1    Liem, A.2    Pitot, H.3    Lambert, P.F.4
  • 25
    • 0029851189 scopus 로고    scopus 로고
    • Altered expression of insulin-like growth factor I and its receptor during multistage carcinogenesis in mouse skin
    • Rho O, Bol DK, You J, Beltran L, Rupp T, DiGiovanni J. Altered expression of insulin-like growth factor I and its receptor during multistage carcinogenesis in mouse skin. Mol Carcinog 1996;17:62-9.
    • (1996) Mol Carcinog , vol.17 , pp. 62-69
    • Rho, O.1    Bol, D.K.2    You, J.3    Beltran, L.4    Rupp, T.5    DiGiovanni, J.6
  • 26
    • 0032538428 scopus 로고    scopus 로고
    • Transcriptional regulation of cyclooxygenase-2 in mouse skin carcinoma cells. Regulatory role of CCAAT/enhancer-binding proteins in the differential expression of cyclooxygenase-2 in normal and neoplastic tissues
    • Kim Y, Fischer SM. Transcriptional regulation of cyclooxygenase-2 in mouse skin carcinoma cells. Regulatory role of CCAAT/enhancer-binding proteins in the differential expression of cyclooxygenase-2 in normal and neoplastic tissues. J Biol Chem 1998;273:27686-94.
    • (1998) J Biol Chem , vol.273 , pp. 27686-27694
    • Kim, Y.1    Fischer, S.M.2
  • 28
    • 0035825611 scopus 로고    scopus 로고
    • A novel transformation suppressor, Pdcd4, inhibits AP-1 transactivation but not NF-κB or ODC transactivation
    • Yang HS, Jansen AP, Nair R, et al. A novel transformation suppressor, Pdcd4, inhibits AP-1 transactivation but not NF-κB or ODC transactivation. Oncogene 2001;20:669-76.
    • (2001) Oncogene , vol.20 , pp. 669-676
    • Yang, H.S.1    Jansen, A.P.2    Nair, R.3
  • 29
    • 20144365155 scopus 로고    scopus 로고
    • Inhibitors of the arachidonic acid pathway and peroxisome proliferator-activated receptor ligands have superadditive effects on lung cancer growth inhibition
    • Avis I, Martinez A, Tauler J, et al. Inhibitors of the arachidonic acid pathway and peroxisome proliferator-activated receptor ligands have superadditive effects on lung cancer growth inhibition. Cancer Res 2005;65: 4181-90.
    • (2005) Cancer Res , vol.65 , pp. 4181-4190
    • Avis, I.1    Martinez, A.2    Tauler, J.3
  • 30
    • 0242475362 scopus 로고    scopus 로고
    • Osteopontin induction is required for tumor promoter-induced transformation of preneoplastic mouse cells
    • Chang PL, Cao M, Hicks P. Osteopontin induction is required for tumor promoter-induced transformation of preneoplastic mouse cells. Carcinogenesis 2003;24: 1749-58.
    • (2003) Carcinogenesis , vol.24 , pp. 1749-1758
    • Chang, P.L.1    Cao, M.2    Hicks, P.3
  • 31
    • 33644683515 scopus 로고    scopus 로고
    • Inhibition of invasion, angiogenesis, tumor growth, and metastasis by adenovirus-mediated transfer of antisense uPAR and MMP-9 in non-small cell lung cancer cells
    • Rao JS, Gondi C, Chetty C, et al. Inhibition of invasion, angiogenesis, tumor growth, and metastasis by adenovirus-mediated transfer of antisense uPAR and MMP-9 in non-small cell lung cancer cells. Mol Cancer Ther 2005;4:1399-408.
    • (2005) Mol Cancer Ther , vol.4 , pp. 1399-1408
    • Rao, J.S.1    Gondi, C.2    Chetty, C.3
  • 32
    • 26444486892 scopus 로고    scopus 로고
    • Inhibition of invasion and metastasis in oral cancer by targeting urokinase-type plasminogen activator receptor
    • Nozaki S, Endo Y, Nakahara H, et al. Inhibition of invasion and metastasis in oral cancer by targeting urokinase-type plasminogen activator receptor. Oral Oncol 2005;41:971-7.
    • (2005) Oral Oncol , vol.41 , pp. 971-977
    • Nozaki, S.1    Endo, Y.2    Nakahara, H.3
  • 33
    • 12144262454 scopus 로고    scopus 로고
    • Production and in vivo effects of chemokines CXCL1-3/KC and CCL2/JE in a model of inflammatory angiogenesis in mice
    • Barcelos LS, Talvani A, Teixeira AS, Cassali GD, Andrade SP, Teixeira MM. Production and in vivo effects of chemokines CXCL1-3/KC and CCL2/JE in a model of inflammatory angiogenesis in mice. Inflamm Res 2004; 53:576-84.
    • (2004) Inflamm Res , vol.53 , pp. 576-584
    • Barcelos, L.S.1    Talvani, A.2    Teixeira, A.S.3    Cassali, G.D.4    Andrade, S.P.5    Teixeira, M.M.6
  • 34
    • 0042337376 scopus 로고    scopus 로고
    • AP-1 complexes containing c-Jun and JunB cause cellular transformation of Rat1a fibroblasts and share transcriptional targets
    • Leaner VD, Kinoshita I, Birrer MJ. AP-1 complexes containing c-Jun and JunB cause cellular transformation of Rat1a fibroblasts and share transcriptional targets. Oncogene 2003;22:5619-29.
    • (2003) Oncogene , vol.22 , pp. 5619-5629
    • Leaner, V.D.1    Kinoshita, I.2    Birrer, M.J.3
  • 35
    • 0038631788 scopus 로고    scopus 로고
    • Identification of c-Jun-responsive genes in Rat-1a cells using multiple techniques: Increased expression of stathmin is necessary for c-Jun-mediated anchorage-independent growth
    • Kinoshita I, Leaner V, Katabami M, et al. Identification of c-Jun-responsive genes in Rat-1a cells using multiple techniques: increased expression of stathmin is necessary for c-Jun-mediated anchorage-independent growth. Oncogene 2003;22:2710-22.
    • (2003) Oncogene , vol.22 , pp. 2710-2722
    • Kinoshita, I.1    Leaner, V.2    Katabami, M.3
  • 36
    • 0037166271 scopus 로고    scopus 로고
    • Cyclooxygenase-2 is overexpressed in HER-2/neupositive breast cancer: Evidence for involvement of AP-1 and PEA3
    • Subbaramaiah K, Norton L, Gerald W, Dannenberg AJ. Cyclooxygenase-2 is overexpressed in HER-2/neupositive breast cancer: evidence for involvement of AP-1 and PEA3. J Biol Chem 2002;277:18649-57.
    • (2002) J Biol Chem , vol.277 , pp. 18649-18657
    • Subbaramaiah, K.1    Norton, L.2    Gerald, W.3    Dannenberg, A.J.4
  • 37
    • 0034107666 scopus 로고    scopus 로고
    • Bcl-3 expression promotes cell survival following interleukin-4 deprivation and is controlled by AP1 and AP1-like transcription factors
    • Rebollo A, Dumoutier L, Renauld JC, Zaballos A, Ayllon V, Martinez AC. Bcl-3 expression promotes cell survival following interleukin-4 deprivation and is controlled by AP1 and AP1-like transcription factors. Mol Cell Biol 2000;20:3407-16.
    • (2000) Mol Cell Biol , vol.20 , pp. 3407-3416
    • Rebollo, A.1    Dumoutier, L.2    Renauld, J.C.3    Zaballos, A.4    Ayllon, V.5    Martinez, A.C.6
  • 38
    • 0033950160 scopus 로고    scopus 로고
    • Role of activating protein-1 and high mobility group-I (Y) protein in the induction of CD44 gene expression by interleukin-1β in vascular smooth muscle cells
    • Foster LC, Wiesel P, Huggins GS, et al. Role of activating protein-1 and high mobility group-I (Y) protein in the induction of CD44 gene expression by interleukin-1β in vascular smooth muscle cells. FASEB J 2000;14:368-78.
    • (2000) FASEB J , vol.14 , pp. 368-378
    • Foster, L.C.1    Wiesel, P.2    Huggins, G.S.3
  • 39
    • 2642549186 scopus 로고    scopus 로고
    • Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: Role of INK4a/CAV-1 in mammary epithelial cell hyperplasia
    • Williams TM, Lee H, Cheung MW, et al. Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: role of INK4a/CAV-1 in mammary epithelial cell hyperplasia. J Biol Chem 2004;279:24745-56.
    • (2004) J Biol Chem , vol.279 , pp. 24745-24756
    • Williams, T.M.1    Lee, H.2    Cheung, M.W.3
  • 40
    • 0037197922 scopus 로고    scopus 로고
    • The bimodal regulation of epidermal growth factor signaling by human Sprouty proteins
    • Egan JE, Hall AB, Yatsula BA Bar-Sagi D. The bimodal regulation of epidermal growth factor signaling by human Sprouty proteins. Proc Natl Acad Sci U S A 2002;99:6041-6.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 6041-6046
    • Egan, J.E.1    Hall, A.B.2    Yatsula, B.A.3    Bar-Sagi, D.4
  • 41
    • 4143124753 scopus 로고    scopus 로고
    • Signal transduction pathways regulating cyclooxygenase-2 expression: Potential molecular targets for chemoprevention
    • Chun KS, Surh YJ. Signal transduction pathways regulating cyclooxygenase-2 expression: potential molecular targets for chemoprevention. Biochem Pharmacol 2004;68:1089-100.
    • (2004) Biochem Pharmacol , vol.68 , pp. 1089-1100
    • Chun, K.S.1    Surh, Y.J.2
  • 42
    • 33645850713 scopus 로고    scopus 로고
    • 2 promotes angiogenesis in colorectal cancer
    • 2 promotes angiogenesis in colorectal cancer. J Exp Med 2006;203:941-51.
    • (2006) J Exp Med , vol.203 , pp. 941-951
    • Wang, D.1    Wang, H.2    Brown, J.3
  • 43
    • 0037967272 scopus 로고    scopus 로고
    • Tumorigenesis and the angiogenic switch
    • Bergers G, Benjamin LE. Tumorigenesis and the angiogenic switch. Nat Rev Cancer 2003;3:401-10.
    • (2003) Nat Rev Cancer , vol.3 , pp. 401-410
    • Bergers, G.1    Benjamin, L.E.2
  • 44
    • 28244456279 scopus 로고    scopus 로고
    • Tumor inflammatory angiogenesis and its chemoprevention
    • Albini A, Tosetti F, Benelli R, Noonan DM. Tumor inflammatory angiogenesis and its chemoprevention. Cancer Res 2005;65:10637-41.
    • (2005) Cancer Res , vol.65 , pp. 10637-10641
    • Albini, A.1    Tosetti, F.2    Benelli, R.3    Noonan, D.M.4
  • 45
    • 20444463535 scopus 로고    scopus 로고
    • Mechanisms of disease: Inflammatory mediators and cancer prevention
    • Mann JR, Backhand MG, DuBois RN. Mechanisms of disease: inflammatory mediators and cancer prevention. Nat Clin Pract Oncol 2005;2:202-10.
    • (2005) Nat Clin Pract Oncol , vol.2 , pp. 202-210
    • Mann, J.R.1    Backhand, M.G.2    DuBois, R.N.3
  • 46
    • 0036134934 scopus 로고    scopus 로고
    • Transactivation of Fra-1 and consequent activation of AP-1 occur extracellular signal-regulated kinase dependently
    • Young MR, Nair R, Bucheimer N, et al. Transactivation of Fra-1 and consequent activation of AP-1 occur extracellular signal-regulated kinase dependently. Mol Cell Biol 2002;22:587-98.
    • (2002) Mol Cell Biol , vol.22 , pp. 587-598
    • Young, M.R.1    Nair, R.2    Bucheimer, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.