-
1
-
-
10344263931
-
Neuronal membrane cholesterol loss enhances amyloid peptide generation
-
Abad-Rodriguez J, Ledesma MD, Craessaerts K, Perga S, Medina M, Delacourte A, Dingwall C, De Strooper B, Dotti CG (2004) Neuronal membrane cholesterol loss enhances amyloid peptide generation. J. Cell Biol. 167, 953-960.
-
(2004)
J. Cell Biol.
, vol.167
, pp. 953-960
-
-
Abad-Rodriguez, J.1
Ledesma, M.D.2
Craessaerts, K.3
Perga, S.4
Medina, M.5
Delacourte, A.6
Dingwall, C.7
De Strooper, B.8
Dotti, C.G.9
-
2
-
-
0025957105
-
Synthesis of phosphatidylethanolamine and ethanolamine plasmalogen by the CDP-ethanolamine and decarboxylase pathways in rat heart, kidney and liver
-
Arthur G, Page L (1991) Synthesis of phosphatidylethanolamine and ethanolamine plasmalogen by the CDP-ethanolamine and decarboxylase pathways in rat heart, kidney and liver. Biochem. J. 273(Pt 1), 121-125.
-
(1991)
Biochem. J.
, vol.273
, Issue.PART 1
, pp. 121-125
-
-
Arthur, G.1
Page, L.2
-
3
-
-
79953305108
-
Functional and topological analysis of Pen-2, the fourth subunit of the gamma-secretase complex
-
Bammens L, Chavez-Gutierrez L, Tolia A, Zwijsen A, De Strooper B (2011) Functional and topological analysis of Pen-2, the fourth subunit of the gamma-secretase complex. J. Biol. Chem. 286, 12271-12282.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 12271-12282
-
-
Bammens, L.1
Chavez-Gutierrez, L.2
Tolia, A.3
Zwijsen, A.4
De Strooper, B.5
-
4
-
-
33845261493
-
A rapid method for total lipid extraction and purification
-
Bligh EG, Dyer WJ (1959) A rapid method for total lipid extraction and purification. Can. J. Biochem. Physiol. 37, 911-917.
-
(1959)
Can. J. Biochem. Physiol.
, vol.37
, pp. 911-917
-
-
Bligh, E.G.1
Dyer, W.J.2
-
5
-
-
29444455075
-
Drosophila as a model for human neurodegenerative disease
-
Bilen J, Bonini NM (2005) Drosophila as a model for human neurodegenerative disease. Annu. Rev. Genet. 39, 153-171.
-
(2005)
Annu. Rev. Genet.
, vol.39
, pp. 153-171
-
-
Bilen, J.1
Bonini, N.M.2
-
6
-
-
0028938736
-
Phosphatidylethanolamine is required for in vivo function of the membrane-associated lactose permease of Escherichia coli
-
Bogdanov M, Dowhan W (1995) Phosphatidylethanolamine is required for in vivo function of the membrane-associated lactose permease of Escherichia coli. J. Biol. Chem. 270, 732-739.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 732-739
-
-
Bogdanov, M.1
Dowhan, W.2
-
7
-
-
15844379770
-
A phospholipid acts as a chaperone in assembly of a membrane transport protein
-
Bogdanov M, Sun J, Kaback HR, Dowhan W (1996) A phospholipid acts as a chaperone in assembly of a membrane transport protein. J. Biol. Chem. 271, 11615-11618.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 11615-11618
-
-
Bogdanov, M.1
Sun, J.2
Kaback, H.R.3
Dowhan, W.4
-
8
-
-
0033617356
-
Phospholipid-assisted refolding of an integral membrane protein. Minimum structural features for phosphatidylethanolamine to act as a molecular chaperone
-
Bogdanov M, Umeda M, Dowhan W (1999) Phospholipid-assisted refolding of an integral membrane protein. Minimum structural features for phosphatidylethanolamine to act as a molecular chaperone. J. Biol. Chem. 274, 12339-12345.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 12339-12345
-
-
Bogdanov, M.1
Umeda, M.2
Dowhan, W.3
-
9
-
-
58149290253
-
Lipids in the assembly of membrane proteins and organization of protein supercomplexes: implications for lipid-linked disorders
-
Bogdanov M, Mileykovskaya E, Dowhan W (2008) Lipids in the assembly of membrane proteins and organization of protein supercomplexes: implications for lipid-linked disorders. Subcell. Biochem. 49, 197-239.
-
(2008)
Subcell. Biochem.
, vol.49
, pp. 197-239
-
-
Bogdanov, M.1
Mileykovskaya, E.2
Dowhan, W.3
-
10
-
-
0141482022
-
Exclusively targeting beta-secretase to lipid rafts by GPI-anchor addition up-regulates beta-site processing of the amyloid precursor protein
-
Cordy JM, Hussain I, Dingwall C, Hooper NM, Turner AJ (2003) Exclusively targeting beta-secretase to lipid rafts by GPI-anchor addition up-regulates beta-site processing of the amyloid precursor protein. Proc. Natl. Acad. Sci. U S A 100, 11735-11740.
-
(2003)
Proc. Natl. Acad. Sci. U S A
, vol.100
, pp. 11735-11740
-
-
Cordy, J.M.1
Hussain, I.2
Dingwall, C.3
Hooper, N.M.4
Turner, A.J.5
-
11
-
-
0033535504
-
A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain
-
De Strooper B, Annaert W, Cupers P, Saftig P, Craessaerts K, Mumm JS, Schroeter EH, Schrijvers V, Wolfe MS, Ray WJ, Goate A, Kopan R (1999) A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain. Nature 398, 518-522.
-
(1999)
Nature
, vol.398
, pp. 518-522
-
-
De Strooper, B.1
Annaert, W.2
Cupers, P.3
Saftig, P.4
Craessaerts, K.5
Mumm, J.S.6
Schroeter, E.H.7
Schrijvers, V.8
Wolfe, M.S.9
Ray, W.J.10
Goate, A.11
Kopan, R.12
-
12
-
-
67650732710
-
Lipid-dependent membrane protein topogenesis
-
Dowhan W, Bogdanov M (2009) Lipid-dependent membrane protein topogenesis. Annu. Rev. Biochem. 78, 515-540.
-
(2009)
Annu. Rev. Biochem.
, vol.78
, pp. 515-540
-
-
Dowhan, W.1
Bogdanov, M.2
-
13
-
-
0002002057
-
Lipid metabolism
-
(K GA, G LI, eds). Elmsford, NY
-
Downer RGH (1985). Lipid metabolism. In Comprehensive Insect Biochemistry and Pharmacology Pergamon (K GA, G LI, eds). Elmsford, NY 10, 77-113.
-
(1985)
Comprehensive Insect Biochemistry and Pharmacology Pergamon
, vol.10
, pp. 77-113
-
-
Downer, R.G.H.1
-
14
-
-
0037173115
-
Presenilin and nicastrin regulate each other and determine amyloid beta-peptide production via complex formation
-
Edbauer D, Winkler E, Haass C, Steiner H (2002) Presenilin and nicastrin regulate each other and determine amyloid beta-peptide production via complex formation. Proc. Natl. Acad. Sci. U. S. A. 99, 8666-8671.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 8666-8671
-
-
Edbauer, D.1
Winkler, E.2
Haass, C.3
Steiner, H.4
-
15
-
-
0037421206
-
Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts
-
Ehehalt R, Keller P, Haass C, Thiele C, Simons K (2003) Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts. J. Cell Biol. 160, 113-123.
-
(2003)
J. Cell Biol.
, vol.160
, pp. 113-123
-
-
Ehehalt, R.1
Keller, P.2
Haass, C.3
Thiele, C.4
Simons, K.5
-
16
-
-
4644257963
-
Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway
-
Esselens C, Oorschot V, Baert V, Raemaekers T, Spittaels K, Serneels L, Zheng H, Saftig P, De Strooper B, Klumperman J, Annaert W (2004) Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway. J. Cell Biol. 166, 1041-1054.
-
(2004)
J. Cell Biol.
, vol.166
, pp. 1041-1054
-
-
Esselens, C.1
Oorschot, V.2
Baert, V.3
Raemaekers, T.4
Spittaels, K.5
Serneels, L.6
Zheng, H.7
Saftig, P.8
De Strooper, B.9
Klumperman, J.10
Annaert, W.11
-
17
-
-
0347093518
-
Detergent-dependent dissociation of active gamma-secretase reveals an interaction between Pen-2 and PS1-NTF and offers a model for subunit organization within the complex
-
Fraering PC, LaVoie MJ, Ye W, Ostaszewski BL, Kimberly WT, Selkoe DJ, Wolfe MS (2004) Detergent-dependent dissociation of active gamma-secretase reveals an interaction between Pen-2 and PS1-NTF and offers a model for subunit organization within the complex. Biochemistry 43, 323-333.
-
(2004)
Biochemistry
, vol.43
, pp. 323-333
-
-
Fraering, P.C.1
LaVoie, M.J.2
Ye, W.3
Ostaszewski, B.L.4
Kimberly, W.T.5
Selkoe, D.J.6
Wolfe, M.S.7
-
18
-
-
45549093275
-
Independent inhibition of Alzheimer disease beta- and gamma-secretase cleavage by lowered cholesterol levels
-
Grimm MO, Grimm HS, Tomic I, Beyreuther K, Hartmann T, Bergmann C (2008) Independent inhibition of Alzheimer disease beta- and gamma-secretase cleavage by lowered cholesterol levels. J. Biol. Chem. 283, 11302-11311.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 11302-11311
-
-
Grimm, M.O.1
Grimm, H.S.2
Tomic, I.3
Beyreuther, K.4
Hartmann, T.5
Bergmann, C.6
-
19
-
-
0142247476
-
A reporter for amyloid precursor protein gamma-secretase activity in Drosophila
-
Guo M, Hong EJ, Fernandes J, Zipursky SL, Hay BA (2003) A reporter for amyloid precursor protein gamma-secretase activity in Drosophila. Hum. Mol. Genet. 12, 2669-2678.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 2669-2678
-
-
Guo, M.1
Hong, E.J.2
Fernandes, J.3
Zipursky, S.L.4
Hay, B.A.5
-
20
-
-
33847662852
-
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide
-
Haass C, Selkoe DJ (2007) Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide. Nat. Rev. Mol. Cell Biol. 8, 101-112.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 101-112
-
-
Haass, C.1
Selkoe, D.J.2
-
21
-
-
25844496169
-
Lipid alterations in the earliest clinically recognizable stage of Alzheimer's disease: implication of the role of lipids in the pathogenesis of Alzheimer's disease
-
Han X (2005) Lipid alterations in the earliest clinically recognizable stage of Alzheimer's disease: implication of the role of lipids in the pathogenesis of Alzheimer's disease. Curr. Alzheimer Res. 2: 65-77.
-
(2005)
Curr. Alzheimer Res.
, vol.2
, pp. 65-77
-
-
Han, X.1
-
22
-
-
0027053153
-
Lipid composition of subcellular membranes from larvae and prepupae of Drosophila melanogaster
-
Jones HE, Harwood JL, Bowen ID, Griffiths G (1992) Lipid composition of subcellular membranes from larvae and prepupae of Drosophila melanogaster. Lipids 27, 984-987.
-
(1992)
Lipids
, vol.27
, pp. 984-987
-
-
Jones, H.E.1
Harwood, J.L.2
Bowen, I.D.3
Griffiths, G.4
-
23
-
-
0002720677
-
Metabolism of lipides
-
Kennedy EP (1957) Metabolism of lipides. Annu. Rev. Biochem. 26, 119-148.
-
(1957)
Annu. Rev. Biochem.
, vol.26
, pp. 119-148
-
-
Kennedy, E.P.1
-
24
-
-
0035826909
-
Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10
-
Kojro E, Gimpl G, Lammich S, Marz W, Fahrenholz F (2001) Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10. Proc. Natl. Acad. Sci. U. S. A. 98, 5815-5820.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 5815-5820
-
-
Kojro, E.1
Gimpl, G.2
Lammich, S.3
Marz, W.4
Fahrenholz, F.5
-
25
-
-
0031031859
-
Sphingolipids - the enigmatic lipid class: biochemistry, physiology, and pathophysiology
-
Merrill Jr AH, Schmelz EM, Dillehay DL, Spiegel S, Shayman JA, Schroeder JJ, Riley RT, Voss KA, Wang E (1997) Sphingolipids - the enigmatic lipid class: biochemistry, physiology, and pathophysiology. Toxicol. Appl. Pharmacol. 142, 208-225.
-
(1997)
Toxicol. Appl. Pharmacol.
, vol.142
, pp. 208-225
-
-
Merrill Jr, A.H.1
Schmelz, E.M.2
Dillehay, D.L.3
Spiegel, S.4
Shayman, J.A.5
Schroeder, J.J.6
Riley, R.T.7
Voss, K.A.8
Wang, E.9
-
26
-
-
0242321947
-
Presenilins mutated at Asp-257 or Asp-385 restore Pen-2 expression and nicastrin glycosylation but remain catalytically inactive in the absence of wild type presenilin
-
Nyabi O, Bentahir M, Horre K, Herreman A, Gottardi-Littell N, Van Broeckhoven C, Merchiers P, Spittaels K, Annaert W, De Strooper B (2003) Presenilins mutated at Asp-257 or Asp-385 restore Pen-2 expression and nicastrin glycosylation but remain catalytically inactive in the absence of wild type presenilin. J. Biol. Chem. 278, 43430-43436.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 43430-43436
-
-
Nyabi, O.1
Bentahir, M.2
Horre, K.3
Herreman, A.4
Gottardi-Littell, N.5
Van Broeckhoven, C.6
Merchiers, P.7
Spittaels, K.8
Annaert, W.9
De Strooper, B.10
-
27
-
-
53049089639
-
Direct and potent regulation of gamma-secretase by its lipid microenvironment
-
Osenkowski P, Ye W, Wang R, Wolfe MS, Selkoe DJ (2008) Direct and potent regulation of gamma-secretase by its lipid microenvironment. J. Biol. Chem. 283, 22529-22540.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 22529-22540
-
-
Osenkowski, P.1
Ye, W.2
Wang, R.3
Wolfe, M.S.4
Selkoe, D.J.5
-
28
-
-
67650245818
-
APH1 polar transmembrane residues regulate the assembly and activity of presenilin complexes
-
Pardossi-Piquard R, Yang SP, Kanemoto S, Gu Y, Chen F, Bohm C, Sevalle J, Li T, Wong PC, Checler F, Schmitt-Ulms G, St George-Hyslop P, Fraser PE (2009) APH1 polar transmembrane residues regulate the assembly and activity of presenilin complexes. J. Biol. Chem. 284, 16298-16307.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 16298-16307
-
-
Pardossi-Piquard, R.1
Yang, S.P.2
Kanemoto, S.3
Gu, Y.4
Chen, F.5
Bohm, C.6
Sevalle, J.7
Li, T.8
Wong, P.C.9
Checler, F.10
Schmitt-Ulms, G.11
St George-Hyslop, P.12
Fraser, P.E.13
-
29
-
-
0028108924
-
The Drosophila easily shocked gene: a mutation in a phospholipid synthetic pathway causes seizure, neuronal failure, and paralysis
-
Pavlidis P, Ramaswami M, Tanouye MA (1994) The Drosophila easily shocked gene: a mutation in a phospholipid synthetic pathway causes seizure, neuronal failure, and paralysis. Cell 79, 23-33.
-
(1994)
Cell
, vol.79
, pp. 23-33
-
-
Pavlidis, P.1
Ramaswami, M.2
Tanouye, M.A.3
-
30
-
-
0031942410
-
Regional membrane phospholipid alterations in Alzheimer's disease
-
Prasad MR, Lovell MA, Yatin M, Dhillon H, Markesbery WR (1998) Regional membrane phospholipid alterations in Alzheimer's disease. Neurochem. Res. 23, 81-88.
-
(1998)
Neurochem. Res.
, vol.23
, pp. 81-88
-
-
Prasad, M.R.1
Lovell, M.A.2
Yatin, M.3
Dhillon, H.4
Markesbery, W.R.5
-
31
-
-
77950544727
-
Troubleshooting methods for APP processing in vitro
-
Sastre M (2010) Troubleshooting methods for APP processing in vitro. J. Pharmacol. Toxicol. Methods 61, 86-91.
-
(2010)
J. Pharmacol. Toxicol. Methods
, vol.61
, pp. 86-91
-
-
Sastre, M.1
-
32
-
-
0035066332
-
Alzheimer's disease: genes, proteins, and therapy
-
Selkoe DJ (2001) Alzheimer's disease: genes, proteins, and therapy. Physiol. Rev. 81, 741-766.
-
(2001)
Physiol. Rev.
, vol.81
, pp. 741-766
-
-
Selkoe, D.J.1
-
33
-
-
13444268952
-
Differential contribution of the three Aph1 genes to gamma-secretase activity in vivo
-
Serneels L, Dejaegere T, Craessaerts K, Horre K, Jorissen E, Tousseyn T, Hebert S, Coolen M, Martens G, Zwijsen A, Annaert W, Hartmann D, De Strooper B (2005) Differential contribution of the three Aph1 genes to gamma-secretase activity in vivo. Proc. Natl. Acad. Sci. U S A 102, 1719-1724.
-
(2005)
Proc. Natl. Acad. Sci. U S A
, vol.102
, pp. 1719-1724
-
-
Serneels, L.1
Dejaegere, T.2
Craessaerts, K.3
Horre, K.4
Jorissen, E.5
Tousseyn, T.6
Hebert, S.7
Coolen, M.8
Martens, G.9
Zwijsen, A.10
Annaert, W.11
Hartmann, D.12
De Strooper, B.13
-
34
-
-
65549140727
-
gamma-secretase heterogeneity in the Aph1 subunit: relevance for Alzheimer's disease
-
Serneels L, Van Biervliet J, Craessaerts K, Dejaegere T, Horre K, Van Houtvin T, Esselmann H, Paul S, Schafer MK, Berezovska O, Hyman BT, Sprangers B, Sciot R, Moons L, Jucker M, Yang Z, May PC, Karran E, Wiltfang J, D'Hooge R, De Strooper B (2009) gamma-secretase heterogeneity in the Aph1 subunit: relevance for Alzheimer's disease. Science 324, 639-642.
-
(2009)
Science
, vol.324
, pp. 639-642
-
-
Serneels, L.1
Van Biervliet, J.2
Craessaerts, K.3
Dejaegere, T.4
Horre, K.5
Van Houtvin, T.6
Esselmann, H.7
Paul, S.8
Schafer, M.K.9
Berezovska, O.10
Hyman, B.T.11
Sprangers, B.12
Sciot, R.13
Moons, L.14
Jucker, M.15
Yang, Z.16
May, P.C.17
Karran, E.18
Wiltfang, J.19
D'Hooge, R.20
De Strooper, B.21
more..
-
35
-
-
0005530621
-
Apoptosis is associated with an increase in saturated fatty acid containing phospholipids in the neuronal cell line, HN2-5
-
Singh JK, Dasgupta A, Adayev T, Shahmehdi SA, Hammond D, Banerjee P (1996) Apoptosis is associated with an increase in saturated fatty acid containing phospholipids in the neuronal cell line, HN2-5. Biochim. Biophys. Acta 1304, 171-178.
-
(1996)
Biochim. Biophys. Acta
, vol.1304
, pp. 171-178
-
-
Singh, J.K.1
Dasgupta, A.2
Adayev, T.3
Shahmehdi, S.A.4
Hammond, D.5
Banerjee, P.6
-
36
-
-
40949159198
-
Building gamma-secretase: the bits and pieces
-
Spasic D, Annaert W (2008) Building gamma-secretase: the bits and pieces. J. Cell Sci. 121, 413-420.
-
(2008)
J. Cell Sci.
, vol.121
, pp. 413-420
-
-
Spasic, D.1
Annaert, W.2
-
37
-
-
58049193592
-
Chemical cross-linking provides a model of the gamma-secretase complex subunit architecture and evidence for close proximity of the C-terminal fragment of presenilin with APH-1
-
Steiner H, Winkler E, Haass C (2008) Chemical cross-linking provides a model of the gamma-secretase complex subunit architecture and evidence for close proximity of the C-terminal fragment of presenilin with APH-1. J. Biol. Chem. 283, 34677-34686.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 34677-34686
-
-
Steiner, H.1
Winkler, E.2
Haass, C.3
-
38
-
-
0033639117
-
Requirements for presenilin-dependent cleavage of notch and other transmembrane proteins
-
Struhl G, Adachi A (2000) Requirements for presenilin-dependent cleavage of notch and other transmembrane proteins. Mol. Cell 6, 625-636.
-
(2000)
Mol. Cell
, vol.6
, pp. 625-636
-
-
Struhl, G.1
Adachi, A.2
-
39
-
-
0033535508
-
Presenilin is required for activity and nuclear access of Notch in Drosophila
-
Struhl G, Greenwald I (1999) Presenilin is required for activity and nuclear access of Notch in Drosophila. Nature 398, 522-525.
-
(1999)
Nature
, vol.398
, pp. 522-525
-
-
Struhl, G.1
Greenwald, I.2
-
40
-
-
0028157335
-
Membrane lipids, selectively diminished in Alzheimer brains, suggest synapse loss as a primary event in early-onset form (type I) and demyelination in late-onset form (type II)
-
Svennerholm L, Gottfries CG (1994) Membrane lipids, selectively diminished in Alzheimer brains, suggest synapse loss as a primary event in early-onset form (type I) and demyelination in late-onset form (type II). J. Neurochem. 62, 1039-1047.
-
(1994)
J. Neurochem.
, vol.62
, pp. 1039-1047
-
-
Svennerholm, L.1
Gottfries, C.G.2
-
41
-
-
0037468759
-
The role of presenilin cofactors in the gamma-secretase complex
-
Takasugi N, Tomita T, Hayashi I, Tsuruoka M, Niimura M, Takahashi Y, Thinakaran G, Iwatsubo T (2003) The role of presenilin cofactors in the gamma-secretase complex. Nature 422, 438-441.
-
(2003)
Nature
, vol.422
, pp. 438-441
-
-
Takasugi, N.1
Tomita, T.2
Hayashi, I.3
Tsuruoka, M.4
Niimura, M.5
Takahashi, Y.6
Thinakaran, G.7
Iwatsubo, T.8
-
42
-
-
33644849690
-
Amyloidogenic processing of beta-amyloid precursor protein in intracellular compartments
-
Vetrivel KS, Thinakaran G (2006) Amyloidogenic processing of beta-amyloid precursor protein in intracellular compartments. Neurology 66, S69-S73.
-
(2006)
Neurology
, vol.66
-
-
Vetrivel, K.S.1
Thinakaran, G.2
-
43
-
-
7244258941
-
Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes
-
Vetrivel KS, Cheng H, Lin W, Sakurai T, Li T, Nukina N, Wong PC, Xu H, Thinakaran G (2004) Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes. J. Biol. Chem. 279, 44945-44954.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 44945-44954
-
-
Vetrivel, K.S.1
Cheng, H.2
Lin, W.3
Sakurai, T.4
Li, T.5
Nukina, N.6
Wong, P.C.7
Xu, H.8
Thinakaran, G.9
-
44
-
-
21844448354
-
Spatial segregation of gamma-secretase and substrates in distinct membrane domains
-
Vetrivel KS, Cheng H, Kim SH, Chen Y, Barnes NY, Parent AT, Sisodia SS, Thinakaran G (2005) Spatial segregation of gamma-secretase and substrates in distinct membrane domains. J. Biol. Chem. 280, 25892-25900.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 25892-25900
-
-
Vetrivel, K.S.1
Cheng, H.2
Kim, S.H.3
Chen, Y.4
Barnes, N.Y.5
Parent, A.T.6
Sisodia, S.S.7
Thinakaran, G.8
-
45
-
-
0029559770
-
Neural membrane phospholipids in Alzheimer disease
-
Wells K, Farooqui AA, Liss L, Horrocks LA (1995) Neural membrane phospholipids in Alzheimer disease. Neurochem. Res. 20, 1329-1333.
-
(1995)
Neurochem. Res.
, vol.20
, pp. 1329-1333
-
-
Wells, K.1
Farooqui, A.A.2
Liss, L.3
Horrocks, L.A.4
-
46
-
-
16844367458
-
Functional overexpression of gamma-secretase reveals protease-independent trafficking functions and a critical role of lipids for protease activity
-
Wrigley JD, Schurov I, Nunn EJ, Martin AC, Clarke EE, Ellis S, Bonnert TP, Shearman MS, Beher D (2005) Functional overexpression of gamma-secretase reveals protease-independent trafficking functions and a critical role of lipids for protease activity. J. Biol. Chem. 280, 12523-12535.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 12523-12535
-
-
Wrigley, J.D.1
Schurov, I.2
Nunn, E.J.3
Martin, A.C.4
Clarke, E.E.5
Ellis, S.6
Bonnert, T.P.7
Shearman, M.S.8
Beher, D.9
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