-
1
-
-
84855332531
-
The establishment of early B cell tolerance in humans: Lessons from primary immunodeficiency diseases
-
Meffre, E. 2011. The establishment of early B cell tolerance in humans: Lessons from primary immunodeficiency diseases. Ann. N.Y. Acad. Sci. 1246: 1-10. doi:.
-
(2011)
Ann. N.Y. Acad. Sci.
, vol.1246
, pp. 1-10
-
-
Meffre, E.1
-
2
-
-
84855304412
-
T cell/B cell interactions in primary immunodeficiencies
-
Tangye, S. 2011. T cell/B cell interactions in primary immunodeficiencies. Ann. N.Y. Acad. Sci. doi:.
-
(2011)
Ann. N.Y. Acad. Sci.
-
-
Tangye, S.1
-
3
-
-
82555186583
-
Regulation of mucosal IgA responses: lessons from primary immunodeficiencies
-
Cerutti, A., M. Cols, M. Gentile, et al. 2011. Regulation of mucosal IgA responses: lessons from primary immunodeficiencies. Ann. N.Y. Acad. Sci. doi:.
-
(2011)
Ann. N.Y. Acad. Sci.
-
-
Cerutti, A.1
Cols, M.2
Gentile, M.3
-
4
-
-
0011118362
-
Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions
-
Hozumi, N. & S. Tonegawa. 1976. Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions. Proc. Natl. Acad. Sci. USA 73: 3628-3632.
-
(1976)
Proc. Natl. Acad. Sci. USA
, vol.73
, pp. 3628-3632
-
-
Hozumi, N.1
Tonegawa, S.2
-
5
-
-
0020534965
-
Somatic generation of antibody diversity
-
Tonegawa, S. 1983. Somatic generation of antibody diversity. Nature 302: 575-581.
-
(1983)
Nature
, vol.302
, pp. 575-581
-
-
Tonegawa, S.1
-
6
-
-
34250212629
-
The transcriptional regulation of B cell lineage commitment
-
Nutt, S.L. & B.L. Kee. 2007. The transcriptional regulation of B cell lineage commitment. Immunity 26: 715-725.
-
(2007)
Immunity
, vol.26
, pp. 715-725
-
-
Nutt, S.L.1
Kee, B.L.2
-
7
-
-
77958542905
-
Load and lock: the molecular mechanisms of B-lymphocyte commitment
-
Zandi, S., D. Bryder & M. Sigvardsson. 2010. Load and lock: the molecular mechanisms of B-lymphocyte commitment. Immunol. Rev. 238: 47-62.
-
(2010)
Immunol. Rev.
, vol.238
, pp. 47-62
-
-
Zandi, S.1
Bryder, D.2
Sigvardsson, M.3
-
8
-
-
0030831130
-
Identification of clonogenic common lymphoid progenitors in mouse bone marrow
-
Kondo, M., I.L. Weissman & K. Akashi. 1997. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 91: 661-672.
-
(1997)
Cell
, vol.91
, pp. 661-672
-
-
Kondo, M.1
Weissman, I.L.2
Akashi, K.3
-
9
-
-
0034624828
-
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
-
Akashi, K. et al. 2000. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 404: 193-197.
-
(2000)
Nature
, vol.404
, pp. 193-197
-
-
Akashi, K.1
-
10
-
-
0034717335
-
Regulation of B lymphocyte and macrophage development by graded expression of PU.1
-
DeKoter, R.P. & H. Singh. 2000. Regulation of B lymphocyte and macrophage development by graded expression of PU.1. Science 288: 1439-1441.
-
(2000)
Science
, vol.288
, pp. 1439-1441
-
-
DeKoter, R.P.1
Singh, H.2
-
11
-
-
0033231420
-
Defects in hemopoietic stem cell activity in Ikaros mutant mice
-
Nichogiannopoulou, A. et al. 1999. Defects in hemopoietic stem cell activity in Ikaros mutant mice. J. Exp. Med. 190: 1201-1214.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1201-1214
-
-
Nichogiannopoulou, A.1
-
12
-
-
50849143861
-
B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic progenitor cells
-
Mansson, R. et al. 2008. B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic progenitor cells. Blood 112: 1048-1055.
-
(2008)
Blood
, vol.112
, pp. 1048-1055
-
-
Mansson, R.1
-
13
-
-
33645081733
-
Lineage specification and plasticity in CD19-early B cell precursors
-
Rumfelt, L.L. et al. 2006. Lineage specification and plasticity in CD19-early B cell precursors. J. Exp. Med. 203: 675-687.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 675-687
-
-
Rumfelt, L.L.1
-
14
-
-
79960106880
-
Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment
-
Notta, F. et al. 2011. Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment. Science 333: 218-221.
-
(2011)
Science
, vol.333
, pp. 218-221
-
-
Notta, F.1
-
15
-
-
0028784287
-
Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset
-
Galy, A. et al. 1995. Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset. Immunity 3: 459-473.
-
(1995)
Immunity
, vol.3
, pp. 459-473
-
-
Galy, A.1
-
16
-
-
77950548072
-
Ordering human CD34+CD10-CD19+ pre/pro-B-cell and CD19- common lymphoid progenitor stages in two pro-B-cell development pathways
-
Sanz, E. et al. 2010. Ordering human CD34+CD10-CD19+ pre/pro-B-cell and CD19- common lymphoid progenitor stages in two pro-B-cell development pathways. Proc. Natl. Acad. Sci. USA 107: 5925-5930.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 5925-5930
-
-
Sanz, E.1
-
17
-
-
77958539498
-
The density of CD10 corresponds to commitment and progression in the human B lymphoid lineage
-
Ichii, M. et al. 2010. The density of CD10 corresponds to commitment and progression in the human B lymphoid lineage. PLoS One 5: e12954.
-
(2010)
PLoS One
, vol.5
-
-
Ichii, M.1
-
18
-
-
27144461642
-
Ig gene rearrangement steps are initiated in early human precursor B cell subsets and correlate with specific transcription factor expression
-
van Zelm, M.C. et al. 2005. Ig gene rearrangement steps are initiated in early human precursor B cell subsets and correlate with specific transcription factor expression. J. Immunol. 175: 5912-5922.
-
(2005)
J. Immunol.
, vol.175
, pp. 5912-5922
-
-
van Zelm, M.C.1
-
19
-
-
0030840883
-
Ig D(H) gene segment transcription and rearrangement before surface expression of the pan-B-cell marker CD19 in normal human bone marrow
-
Bertrand, F.E., 3rd, et al. 1997. Ig D(H) gene segment transcription and rearrangement before surface expression of the pan-B-cell marker CD19 in normal human bone marrow. Blood 90: 736-744.
-
(1997)
Blood
, vol.90
, pp. 736-744
-
-
Bertrand 3rd, F.E.1
-
20
-
-
0029818656
-
A human non-XLA immunodeficiency disease characterized by blockage of B cell development at an early proB cell stage
-
Meffre, E. et al. 1996. A human non-XLA immunodeficiency disease characterized by blockage of B cell development at an early proB cell stage. J. Clin. Invest. 98: 1519-1526.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 1519-1526
-
-
Meffre, E.1
-
21
-
-
0030994385
-
Stimulation of V(D)J cleavage by high mobility group proteins
-
van Gent, D.C. et al. 1997. Stimulation of V(D)J cleavage by high mobility group proteins. EMBO J. 16: 2665-2670.
-
(1997)
EMBO J.
, vol.16
, pp. 2665-2670
-
-
van Gent, D.C.1
-
22
-
-
0028805853
-
Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps
-
McBlane, J.F. et al. 1995. Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps. Cell 83: 387-395.
-
(1995)
Cell
, vol.83
, pp. 387-395
-
-
McBlane, J.F.1
-
23
-
-
0030964130
-
A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage
-
Hiom, K. & M. Gellert. 1997. A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage. Cell 88: 65-72.
-
(1997)
Cell
, vol.88
, pp. 65-72
-
-
Hiom, K.1
Gellert, M.2
-
24
-
-
63449084054
-
MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks
-
Helmink, B.A. et al. 2009. MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks. J. Exp. Med. 206: 669-679.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 669-679
-
-
Helmink, B.A.1
-
25
-
-
77954731256
-
Loss of juxtaposition of RAG-induced immunoglobulin DNA ends is implicated in the precursor B-cell differentiation defect in NBS patients
-
van der Burg, M. et al. 2010. Loss of juxtaposition of RAG-induced immunoglobulin DNA ends is implicated in the precursor B-cell differentiation defect in NBS patients. Blood 115: 4770-4777.
-
(2010)
Blood
, vol.115
, pp. 4770-4777
-
-
van der Burg, M.1
-
26
-
-
0035313998
-
How to make ends meet in V(D)J recombination
-
Grawunder, U. & E. Harfst. 2001. How to make ends meet in V(D)J recombination. Curr. Opin. Immunol. 13: 186-194.
-
(2001)
Curr. Opin. Immunol.
, vol.13
, pp. 186-194
-
-
Grawunder, U.1
Harfst, E.2
-
27
-
-
36949012967
-
Non-homologous end-joining, a sticky affair
-
van Gent, D.C. & M. van der Burg. 2007. Non-homologous end-joining, a sticky affair. Oncogene 26: 7731-7740.
-
(2007)
Oncogene
, vol.26
, pp. 7731-7740
-
-
van Gent, D.C.1
van der Burg, M.2
-
28
-
-
0027397867
-
The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen
-
Gottlieb, T.M. & S.P. Jackson. 1993. The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen. Cell 72: 131-142.
-
(1993)
Cell
, vol.72
, pp. 131-142
-
-
Gottlieb, T.M.1
Jackson, S.P.2
-
29
-
-
0029778191
-
Requirement for Ku80 in growth and immunoglobulin V(D)J recombination
-
Nussenzweig, A. et al. 1996. Requirement for Ku80 in growth and immunoglobulin V(D)J recombination. Nature 382: 551-555.
-
(1996)
Nature
, vol.382
, pp. 551-555
-
-
Nussenzweig, A.1
-
30
-
-
0035917489
-
Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency
-
Moshous, D. et al. 2001. Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency. Cell 105: 177-186.
-
(2001)
Cell
, vol.105
, pp. 177-186
-
-
Moshous, D.1
-
31
-
-
0031925532
-
Structure of nonhairpin coding-end DNA breaks in cells undergoing V(D)J recombination
-
Schlissel, M.S. 1998. Structure of nonhairpin coding-end DNA breaks in cells undergoing V(D)J recombination. Mol. Cell. Biol. 18: 2029-2037.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 2029-2037
-
-
Schlissel, M.S.1
-
32
-
-
0033920225
-
Terminal deoxynucleotidyl transferase and repertoire development
-
Benedict, C.L. et al. 2000. Terminal deoxynucleotidyl transferase and repertoire development. Immunol. Rev. 175: 150-157.
-
(2000)
Immunol. Rev.
, vol.175
, pp. 150-157
-
-
Benedict, C.L.1
-
33
-
-
0035180391
-
The long isoform of terminal deoxynucleotidyl transferase enters the nucleus and, rather than catalyzing nontemplated nucleotide addition, modulates the catalytic activity of the short isoform
-
Benedict, C.L., S. Gilfillan & J.F. Kearney. 2001. The long isoform of terminal deoxynucleotidyl transferase enters the nucleus and, rather than catalyzing nontemplated nucleotide addition, modulates the catalytic activity of the short isoform. J. Exp. Med. 193: 89-99.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 89-99
-
-
Benedict, C.L.1
Gilfillan, S.2
Kearney, J.F.3
-
34
-
-
0031214080
-
Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV
-
Critchlow, S.E., R.P. Bowater & S.P. Jackson. 1997. Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV. Curr. Biol. 7: 588-598.
-
(1997)
Curr. Biol.
, vol.7
, pp. 588-598
-
-
Critchlow, S.E.1
Bowater, R.P.2
Jackson, S.P.3
-
35
-
-
0030743386
-
Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells
-
Grawunder, U. et al. 1997. Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells. Nature 388: 492-495.
-
(1997)
Nature
, vol.388
, pp. 492-495
-
-
Grawunder, U.1
-
36
-
-
31044432090
-
XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining
-
Ahnesorg, P., P. Smith & S.P. Jackson. 2006. XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining. Cell 124: 301-313.
-
(2006)
Cell
, vol.124
, pp. 301-313
-
-
Ahnesorg, P.1
Smith, P.2
Jackson, S.P.3
-
37
-
-
61749104245
-
A DNA-PKcs mutation in a radiosensitive T-B-SCID patient inhibits Artemis activation and nonhomologous end-joining
-
van der Burg, M. et al. 2009. A DNA-PKcs mutation in a radiosensitive T-B-SCID patient inhibits Artemis activation and nonhomologous end-joining. J. Clin. Invest. 119: 91-98.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 91-98
-
-
van der Burg, M.1
-
38
-
-
37549055036
-
Defective Artemis nuclease is characterized by coding joints with microhomology in long palindromic-nucleotide stretches
-
van der Burg, M. et al. 2007. Defective Artemis nuclease is characterized by coding joints with microhomology in long palindromic-nucleotide stretches. Eur. J. Immunol. 37: 3522-3528.
-
(2007)
Eur. J. Immunol.
, vol.37
, pp. 3522-3528
-
-
van der Burg, M.1
-
39
-
-
31044446450
-
A new type of radiosensitive T-B-NK+ severe combined immunodeficiency caused by a LIG4 mutation
-
van der Burg, M. et al. 2006. A new type of radiosensitive T-B-NK+ severe combined immunodeficiency caused by a LIG4 mutation. J. Clin. Invest. 116: 137-145.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 137-145
-
-
van der Burg, M.1
-
40
-
-
0035085624
-
Normal V(D)J recombination in cells from patients with Nijmegen breakage syndrome
-
Harfst, E. et al. 2000. Normal V(D)J recombination in cells from patients with Nijmegen breakage syndrome. Mol. Immunol. 37: 915-929.
-
(2000)
Mol. Immunol.
, vol.37
, pp. 915-929
-
-
Harfst, E.1
-
41
-
-
0027399081
-
Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia
-
Tsukada, S. et al. 1993. Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia. Cell 72: 279-290.
-
(1993)
Cell
, vol.72
, pp. 279-290
-
-
Tsukada, S.1
-
42
-
-
0027441332
-
The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases
-
Vetrie, D. et al. 1993. The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases. Nature 361: 226-233.
-
(1993)
Nature
, vol.361
, pp. 226-233
-
-
Vetrie, D.1
-
43
-
-
67650744339
-
Primary B cell immunodeficiencies: comparisons and contrasts
-
Conley, M.E. et al. 2009. Primary B cell immunodeficiencies: comparisons and contrasts. Annu. Rev. Immunol. 27: 199-227.
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 199-227
-
-
Conley, M.E.1
-
44
-
-
0036790940
-
Galectin-1 is a stromal cell ligand of the pre-B cell receptor (BCR) implicated in synapse formation between pre-B and stromal cells and in pre-BCR triggering
-
Gauthier, L. et al. 2002. Galectin-1 is a stromal cell ligand of the pre-B cell receptor (BCR) implicated in synapse formation between pre-B and stromal cells and in pre-BCR triggering. Proc. Natl. Acad. Sci. USA 99: 13014-13019.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 13014-13019
-
-
Gauthier, L.1
-
45
-
-
33745848466
-
Clustering of pre-B cell integrins induces galectin-1-dependent pre-B cell receptor relocalization and activation
-
Rossi, B. et al. 2006. Clustering of pre-B cell integrins induces galectin-1-dependent pre-B cell receptor relocalization and activation. J. Immunol. 177: 796-803.
-
(2006)
J. Immunol.
, vol.177
, pp. 796-803
-
-
Rossi, B.1
-
46
-
-
67651102911
-
Impaired B-cell development at the pre-BII-cell stage in galectin-1-deficient mice due to inefficient pre-BII/stromal cell interactions
-
Espeli, M. et al. 2009. Impaired B-cell development at the pre-BII-cell stage in galectin-1-deficient mice due to inefficient pre-BII/stromal cell interactions. Blood 113: 5878-5886.
-
(2009)
Blood
, vol.113
, pp. 5878-5886
-
-
Espeli, M.1
-
47
-
-
79952276277
-
Dissection of B-cell development to unravel defects in patients with a primary antibody deficiency
-
van der Burg, M. et al. 2011. Dissection of B-cell development to unravel defects in patients with a primary antibody deficiency. Adv. Exp. Med. Biol. 697: 183-196.
-
(2011)
Adv. Exp. Med. Biol.
, vol.697
, pp. 183-196
-
-
van der Burg, M.1
-
48
-
-
0032526136
-
Kappa chain monoallelic demethylation and the establishment of allelic exclusion
-
Mostoslavsky, R. et al. 1998. Kappa chain monoallelic demethylation and the establishment of allelic exclusion. Genes Dev. 12: 1801-1811.
-
(1998)
Genes Dev.
, vol.12
, pp. 1801-1811
-
-
Mostoslavsky, R.1
-
49
-
-
0035879185
-
Chromatin remodeling at the Ig loci prior to V(D)J recombination
-
Maes, J. et al. 2001. Chromatin remodeling at the Ig loci prior to V(D)J recombination. J. Immunol. 167: 866-874.
-
(2001)
J. Immunol.
, vol.167
, pp. 866-874
-
-
Maes, J.1
-
50
-
-
0034175813
-
Stimulation of V(D)J recombination by histone acetylation
-
McBlane, F. & J. Boyes. 2000. Stimulation of V(D)J recombination by histone acetylation. Curr. Biol. 10: 483-486.
-
(2000)
Curr. Biol.
, vol.10
, pp. 483-486
-
-
McBlane, F.1
Boyes, J.2
-
51
-
-
0035890244
-
Stepwise activation of the immunoglobulin mu heavy chain gene locus
-
Chowdhury, D. & R. Sen. 2001. Stepwise activation of the immunoglobulin mu heavy chain gene locus. EMBO J. 20: 6394-6403.
-
(2001)
EMBO J.
, vol.20
, pp. 6394-6403
-
-
Chowdhury, D.1
Sen, R.2
-
52
-
-
0021983551
-
Developmentally controlled and tissue-specific expression of unrearranged VH gene segments
-
Yancopoulos, G.D. & F.W. Alt. 1985. Developmentally controlled and tissue-specific expression of unrearranged VH gene segments. Cell 40: 271-281.
-
(1985)
Cell
, vol.40
, pp. 271-281
-
-
Yancopoulos, G.D.1
Alt, F.W.2
-
53
-
-
33748850103
-
Regulation of T cell receptor-alpha gene recombination by transcription
-
Abarrategui, I. & M.S. Krangel. 2006. Regulation of T cell receptor-alpha gene recombination by transcription. Nat. Immunol. 7: 1109-1115.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 1109-1115
-
-
Abarrategui, I.1
Krangel, M.S.2
-
54
-
-
41949121201
-
The 3D structure of the immunoglobulin heavy-chain locus: implications for long-range genomic interactions
-
Jhunjhunwala, S. et al. 2008. The 3D structure of the immunoglobulin heavy-chain locus: implications for long-range genomic interactions. Cell 133: 265-279.
-
(2008)
Cell
, vol.133
, pp. 265-279
-
-
Jhunjhunwala, S.1
-
55
-
-
68049086918
-
Chromatin architecture and the generation of antigen receptor diversity
-
Jhunjhunwala, S. et al. 2009. Chromatin architecture and the generation of antigen receptor diversity. Cell 138: 435-448.
-
(2009)
Cell
, vol.138
, pp. 435-448
-
-
Jhunjhunwala, S.1
-
56
-
-
77951215592
-
The mouse immunoglobulin heavy chain V-D intergenic sequence contains insulators that may regulate ordered V(D)J recombination
-
Featherstone, K. et al. 2010. The mouse immunoglobulin heavy chain V-D intergenic sequence contains insulators that may regulate ordered V(D)J recombination. J. Biol. Chem. 285: 9327-9338.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 9327-9338
-
-
Featherstone, K.1
-
57
-
-
0037023361
-
Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development
-
Kosak, S.T. et al. 2002. Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development. Science 296: 158-162.
-
(2002)
Science
, vol.296
, pp. 158-162
-
-
Kosak, S.T.1
-
58
-
-
12344270023
-
Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene
-
Roldan, E. et al. 2005. Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene. Nat. Immunol. 6: 31-41.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 31-41
-
-
Roldan, E.1
-
59
-
-
13244275244
-
Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells
-
Sayegh, C. et al. 2005. Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells. Genes Dev. 19: 322-327.
-
(2005)
Genes Dev.
, vol.19
, pp. 322-327
-
-
Sayegh, C.1
-
60
-
-
1542343974
-
Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene
-
Fuxa, M. et al. 2004. Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene. Genes Dev. 18: 411-422.
-
(2004)
Genes Dev.
, vol.18
, pp. 411-422
-
-
Fuxa, M.1
-
61
-
-
34249035911
-
Yin Yang 1 is a critical regulator of B-cell development
-
Liu, H. et al. 2007. Yin Yang 1 is a critical regulator of B-cell development. Genes Dev. 21: 1179-1189.
-
(2007)
Genes Dev.
, vol.21
, pp. 1179-1189
-
-
Liu, H.1
-
62
-
-
79951737927
-
The distal V(H) gene cluster of the Igh locus contains distinct regulatory elements with Pax5 transcription factor-dependent activity in pro-B cells
-
Ebert, A. et al. 2011. The distal V(H) gene cluster of the Igh locus contains distinct regulatory elements with Pax5 transcription factor-dependent activity in pro-B cells. Immunity 34: 175-187.
-
(2011)
Immunity
, vol.34
, pp. 175-187
-
-
Ebert, A.1
-
63
-
-
23944495647
-
Regulation of interleukin 7-dependent immunoglobulin heavy-chain variable gene rearrangements by transcription factor STAT5
-
Bertolino, E. et al. 2005. Regulation of interleukin 7-dependent immunoglobulin heavy-chain variable gene rearrangements by transcription factor STAT5. Nat. Immunol. 6: 836-843.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 836-843
-
-
Bertolino, E.1
-
64
-
-
75649093758
-
Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development
-
Malin, S. et al. 2010. Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development. Nat. Immunol. 11: 171-179.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 171-179
-
-
Malin, S.1
-
65
-
-
80052153064
-
IL-7R expression and IL-7 signaling confer a distinct phenotype on developing human B-lineage cells
-
Nodland, S.E. et al. 2011. IL-7R expression and IL-7 signaling confer a distinct phenotype on developing human B-lineage cells. Blood 118: 2116-2127.
-
(2011)
Blood
, vol.118
, pp. 2116-2127
-
-
Nodland, S.E.1
-
66
-
-
0033062994
-
B cells are programmed to activate kappa and lambda for rearrangement at consecutive developmental stages
-
Engel, H., A. Rolink & S. Weiss. 1999. B cells are programmed to activate kappa and lambda for rearrangement at consecutive developmental stages. Eur. J. Immunol. 29: 2167-2176.
-
(1999)
Eur. J. Immunol.
, vol.29
, pp. 2167-2176
-
-
Engel, H.1
Rolink, A.2
Weiss, S.3
-
67
-
-
0035865613
-
Ordered recombination of immunoglobulin light chain genes occurs at the IGK locus but seems less strict at the IGL locus
-
van der Burg, M. et al. 2001. Ordered recombination of immunoglobulin light chain genes occurs at the IGK locus but seems less strict at the IGL locus. Blood 97: 1001-1008.
-
(2001)
Blood
, vol.97
, pp. 1001-1008
-
-
van der Burg, M.1
-
68
-
-
0035927178
-
Bruton's tyrosine kinase regulates the activation of gene rearrangements at the lambda light chain locus in precursor B cells in the mouse
-
Dingjan, G.M. et al. 2001. Bruton's tyrosine kinase regulates the activation of gene rearrangements at the lambda light chain locus in precursor B cells in the mouse. J. Exp. Med. 193: 1169-1178.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 1169-1178
-
-
Dingjan, G.M.1
-
69
-
-
70350462285
-
Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci
-
Beck, K. et al. 2009. Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci. J. Exp. Med. 206: 2271-2284.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 2271-2284
-
-
Beck, K.1
-
70
-
-
79959354832
-
CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cells
-
Degner, S.C. et al. CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cells. Proc. Natl. Acad. Sci. USA 108: 9566-9571.
-
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 9566-9571
-
-
Degner, S.C.1
-
71
-
-
28244453738
-
Murine and human IL-7 activate STAT5 and induce proliferation of normal human pro-B cells
-
Johnson, S.E. et al. 2005. Murine and human IL-7 activate STAT5 and induce proliferation of normal human pro-B cells. J. Immunol. 175: 7325-7331.
-
(2005)
J. Immunol.
, vol.175
, pp. 7325-7331
-
-
Johnson, S.E.1
-
72
-
-
0342711256
-
In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death
-
Lam, K.P., R. Kuhn & K. Rajewsky. 1997. In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death. Cell 90: 1073-1083.
-
(1997)
Cell
, vol.90
, pp. 1073-1083
-
-
Lam, K.P.1
Kuhn, R.2
Rajewsky, K.3
-
73
-
-
0030058466
-
Aberrant B cell development and immune response in mice with a compromised BCR complex
-
Torres, R.M. et al. 1996. Aberrant B cell development and immune response in mice with a compromised BCR complex. Science 272: 1804-1808.
-
(1996)
Science
, vol.272
, pp. 1804-1808
-
-
Torres, R.M.1
-
74
-
-
70350304558
-
PI3 kinase signals BCR-dependent mature B cell survival
-
Srinivasan, L. et al. 2009. PI3 kinase signals BCR-dependent mature B cell survival. Cell 139: 573-586.
-
(2009)
Cell
, vol.139
, pp. 573-586
-
-
Srinivasan, L.1
-
75
-
-
33746257209
-
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
-
Engelman, J.A., J. Luo & L.C. Cantley. 2006. The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism. Nat. Rev. Genet. 7: 606-619.
-
(2006)
Nat. Rev. Genet.
, vol.7
, pp. 606-619
-
-
Engelman, J.A.1
Luo, J.2
Cantley, L.C.3
-
76
-
-
31144443212
-
Expansion of functionally immature transitional B cells is associated with human-immunodeficient states characterized by impaired humoral immunity
-
Cuss, A.K. et al. 2006. Expansion of functionally immature transitional B cells is associated with human-immunodeficient states characterized by impaired humoral immunity. J. Immunol. 176: 1506-1516.
-
(2006)
J. Immunol.
, vol.176
, pp. 1506-1516
-
-
Cuss, A.K.1
-
77
-
-
19344376101
-
Identification and characterization of circulating human transitional B cells
-
Sims, G.P. et al. 2005. Identification and characterization of circulating human transitional B cells. Blood 105: 4390-4398.
-
(2005)
Blood
, vol.105
, pp. 4390-4398
-
-
Sims, G.P.1
-
78
-
-
33947431615
-
Replication history of B lymphocytes reveals homeostatic proliferation and extensive antigen-induced B cell expansion
-
van Zelm, M.C. et al. 2007. Replication history of B lymphocytes reveals homeostatic proliferation and extensive antigen-induced B cell expansion. J. Exp. Med. 204: 645-655.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 645-655
-
-
van Zelm, M.C.1
-
79
-
-
0028305693
-
The macrophage is an important and previously unrecognized source of macrophage migration inhibitory factor
-
Calandra, T. et al. 1994. The macrophage is an important and previously unrecognized source of macrophage migration inhibitory factor. J. Exp. Med. 179: 1895-1902.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 1895-1902
-
-
Calandra, T.1
-
80
-
-
84873780558
-
In vitro cell migration as a model for delayed hypersensitivity
-
George, M. & J.H. Vaughan. 1962. In vitro cell migration as a model for delayed hypersensitivity. Proc. Soc. Exp. Biol. Med. 111: 514-521.
-
(1962)
Proc. Soc. Exp. Biol. Med.
, vol.111
, pp. 514-521
-
-
George, M.1
Vaughan, J.H.2
-
81
-
-
40949087882
-
Macrophage migration inhibitory factor induces B cell survival by activation of a CD74-CD44 receptor complex
-
Gore, Y. et al. 2008. Macrophage migration inhibitory factor induces B cell survival by activation of a CD74-CD44 receptor complex. J. Biol. Chem. 283: 2784-2792.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 2784-2792
-
-
Gore, Y.1
-
82
-
-
0037022599
-
Invariant chain induces B cell maturation in a process that is independent of its chaperonic activity
-
Matza, D. et al. 2002. Invariant chain induces B cell maturation in a process that is independent of its chaperonic activity. Proc. Natl. Acad. Sci. USA 99: 3018-3023.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 3018-3023
-
-
Matza, D.1
-
83
-
-
0029742201
-
Requirement for invariant chain in B cell maturation and function
-
Shachar, I. & R.A. Flavell. 1996. Requirement for invariant chain in B cell maturation and function. Science 274: 106-108.
-
(1996)
Science
, vol.274
, pp. 106-108
-
-
Shachar, I.1
Flavell, R.A.2
-
84
-
-
40949140467
-
Perivascular clusters of dendritic cells provide critical survival signals to B cells in bone marrow niches
-
Sapoznikov, A. et al. 2008. Perivascular clusters of dendritic cells provide critical survival signals to B cells in bone marrow niches. Nat. Immunol. 9: 388-395.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 388-395
-
-
Sapoznikov, A.1
-
85
-
-
0038692705
-
BAFF and APRIL: a tutorial on B cell survival
-
Mackay, F. et al. 2003. BAFF and APRIL: a tutorial on B cell survival. Annu. Rev. Immunol. 21: 231-264.
-
(2003)
Annu. Rev. Immunol.
, vol.21
, pp. 231-264
-
-
Mackay, F.1
-
86
-
-
33644755600
-
An APRIL to remember: novel TNF ligands as therapeutic targets
-
Dillon, S.R. et al. 2006. An APRIL to remember: novel TNF ligands as therapeutic targets. Nat. Rev. Drug Discov. 5: 235-246.
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, pp. 235-246
-
-
Dillon, S.R.1
-
87
-
-
17344380531
-
TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease
-
Gross, J.A. et al. 2000. TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease. Nature 404: 995-999.
-
(2000)
Nature
, vol.404
, pp. 995-999
-
-
Gross, J.A.1
-
88
-
-
0034729769
-
Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI
-
Marsters, S.A. et al. 2000. Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI. Curr. Biol. 10: 785-788.
-
(2000)
Curr. Biol.
, vol.10
, pp. 785-788
-
-
Marsters, S.A.1
-
89
-
-
0034601020
-
BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population
-
Thompson, J.S. et al. 2000. BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population. J. Exp. Med. 192: 129-135.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 129-135
-
-
Thompson, J.S.1
-
90
-
-
0034634625
-
Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS
-
Wu, Y. et al. 2000. Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS. J. Biol. Chem. 275: 35478-35485.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 35478-35485
-
-
Wu, Y.1
-
91
-
-
5944227779
-
APRIL and TALL-I and receptors BCMA and TACI: system for regulating humoral immunity
-
Yu, G. et al. 2000. APRIL and TALL-I and receptors BCMA and TACI: system for regulating humoral immunity. Nat. Immunol. 1: 252-256.
-
(2000)
Nat. Immunol.
, vol.1
, pp. 252-256
-
-
Yu, G.1
-
92
-
-
0035860466
-
BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF
-
Thompson, J.S. et al. 2001. BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF. Science 293: 2108-2111.
-
(2001)
Science
, vol.293
, pp. 2108-2111
-
-
Thompson, J.S.1
-
93
-
-
0035797908
-
Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency
-
Yan, M. et al. 2001. Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency. Curr. Biol. 11: 1547-1552.
-
(2001)
Curr. Biol.
, vol.11
, pp. 1547-1552
-
-
Yan, M.1
-
94
-
-
20044369789
-
Heparan sulfate proteoglycan binding promotes APRIL-induced tumor cell proliferation
-
Hendriks, J. et al. 2005. Heparan sulfate proteoglycan binding promotes APRIL-induced tumor cell proliferation. Cell. Death Differ. 12: 637-648.
-
(2005)
Cell. Death Differ.
, vol.12
, pp. 637-648
-
-
Hendriks, J.1
-
95
-
-
20844432040
-
Identification of proteoglycans as the APRIL-specific binding partners
-
Ingold, K. et al. 2005. Identification of proteoglycans as the APRIL-specific binding partners. J. Exp. Med. 201: 1375-1383.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1375-1383
-
-
Ingold, K.1
-
96
-
-
18844447818
-
The role of APRIL and BAFF in lymphocyte activation
-
Schneider, P. 2005. The role of APRIL and BAFF in lymphocyte activation. Curr. Opin. Immunol. 17: 282-289.
-
(2005)
Curr. Opin. Immunol.
, vol.17
, pp. 282-289
-
-
Schneider, P.1
-
97
-
-
17944375043
-
TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease. Impaired B cell maturation in mice lacking BLyS
-
Gross, J.A. et al. 2001. TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease. Impaired B cell maturation in mice lacking BLyS. Immunity 15: 289-302.
-
(2001)
Immunity
, vol.15
, pp. 289-302
-
-
Gross, J.A.1
-
98
-
-
0035860559
-
An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway
-
Schiemann, B. et al. 2001. An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway. Science 293: 2111-2114.
-
(2001)
Science
, vol.293
, pp. 2111-2114
-
-
Schiemann, B.1
-
99
-
-
69549128384
-
B-cell activating factor receptor deficiency is associated with an adult-onset antibody deficiency syndrome in humans
-
Warnatz, K. et al. 2009. B-cell activating factor receptor deficiency is associated with an adult-onset antibody deficiency syndrome in humans. Proc. Natl. Acad. Sci. USA 106: 13945-13950.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 13945-13950
-
-
Warnatz, K.1
-
100
-
-
0026587743
-
CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes
-
Carter, R.H. & D.T. Fearon. 1992. CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes. Science 256: 105-107.
-
(1992)
Science
, vol.256
, pp. 105-107
-
-
Carter, R.H.1
Fearon, D.T.2
-
102
-
-
0034097043
-
Regulation of B lymphocyte responses to foreign and self-antigens by the CD19/CD21 complex
-
Fearon, D.T. & M.C. Carroll. 2000. Regulation of B lymphocyte responses to foreign and self-antigens by the CD19/CD21 complex. Annu. Rev. Immunol. 18: 393-422.
-
(2000)
Annu. Rev. Immunol.
, vol.18
, pp. 393-422
-
-
Fearon, D.T.1
Carroll, M.C.2
-
103
-
-
84873070121
-
Further insights into human CD21 deficiency
-
abstract).
-
Kimmig, L.M. et al. 2008. Further insights into human CD21 deficiency. Clin. Exp. Immunol. 154: 221-221 (abstract).
-
(2008)
Clin. Exp. Immunol.
, vol.154
, pp. 221-221
-
-
Kimmig, L.M.1
-
104
-
-
33646347921
-
An antibody-deficiency syndrome due to mutations in the CD19 gene
-
van Zelm, M.C. et al. 2006. An antibody-deficiency syndrome due to mutations in the CD19 gene. N. Engl. J. Med. 354: 1901-1912.
-
(2006)
N. Engl. J. Med.
, vol.354
, pp. 1901-1912
-
-
van Zelm, M.C.1
-
105
-
-
77951146803
-
CD81 gene defect in humans disrupts CD19 complex formation and leads to antibody deficiency
-
van Zelm, M.C. et al. 2010. CD81 gene defect in humans disrupts CD19 complex formation and leads to antibody deficiency. J. Clin. Invest. 120: 1265-1274.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 1265-1274
-
-
van Zelm, M.C.1
-
106
-
-
0014941813
-
A theory of self-nonself discrimination
-
Bretscher, P. & M. Cohn. 1970. A theory of self-nonself discrimination. Science 169: 1042-1049.
-
(1970)
Science
, vol.169
, pp. 1042-1049
-
-
Bretscher, P.1
Cohn, M.2
-
108
-
-
0029040263
-
T cell independent antigens
-
Mond, J.J. et al. 1995. T cell independent antigens. Curr. Opin. Immunol. 7: 349-354.
-
(1995)
Curr. Opin. Immunol.
, vol.7
, pp. 349-354
-
-
Mond, J.J.1
-
109
-
-
44349195660
-
The regulation of IgA class switching
-
Cerutti, A. 2008. The regulation of IgA class switching. Nat. Rev. Immunol. 8: 421-434.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 421-434
-
-
Cerutti, A.1
-
111
-
-
58149336793
-
Lack of antibody affinity maturation due to poor Toll-like receptor stimulation leads to enhanced respiratory syncytial virus disease
-
Delgado, M.F. et al. 2009. Lack of antibody affinity maturation due to poor Toll-like receptor stimulation leads to enhanced respiratory syncytial virus disease. Nat. Med. 15: 34-41.
-
(2009)
Nat. Med.
, vol.15
, pp. 34-41
-
-
Delgado, M.F.1
-
112
-
-
0035970105
-
CD40-CD40L independent Ig gene hypermutation suggests a second B cell diversification pathway in humans
-
Weller, S. et al. 2001. CD40-CD40L independent Ig gene hypermutation suggests a second B cell diversification pathway in humans. Proc. Natl. Acad. Sci. USA 98: 1166-1170.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 1166-1170
-
-
Weller, S.1
-
113
-
-
77955921430
-
The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88
-
He, B. et al. 2010. The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88. Nat. Immunol. 11: 836-845.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 836-845
-
-
He, B.1
-
114
-
-
34250205694
-
Intestinal bacteria trigger T cell-independent immunoglobulin A(2) class switching by inducing epithelial-cell secretion of the cytokine APRIL
-
He, B. et al. 2007. Intestinal bacteria trigger T cell-independent immunoglobulin A(2) class switching by inducing epithelial-cell secretion of the cytokine APRIL. Immunity 26: 812-826.
-
(2007)
Immunity
, vol.26
, pp. 812-826
-
-
He, B.1
-
115
-
-
80052171651
-
Human memory B cells originate from three distinct germinal center-dependent and -independent maturation pathways
-
Berkowska, M.A. et al. 2011. Human memory B cells originate from three distinct germinal center-dependent and -independent maturation pathways. Blood 118: 2150-2158.
-
(2011)
Blood
, vol.118
, pp. 2150-2158
-
-
Berkowska, M.A.1
-
116
-
-
33748509736
-
A new memory CD27-IgG+ B cell population in peripheral blood expressing VH genes with low frequency of somatic mutation
-
Fecteau, J.F., G. Cote & S. Neron. 2006. A new memory CD27-IgG+ B cell population in peripheral blood expressing VH genes with low frequency of somatic mutation. J. Immunol. 177: 3728-3736.
-
(2006)
J. Immunol.
, vol.177
, pp. 3728-3736
-
-
Fecteau, J.F.1
Cote, G.2
Neron, S.3
-
117
-
-
34248140178
-
A new population of cells lacking expression of CD27 represents a notable component of the B cell memory compartment in systemic lupus erythematosus
-
Wei, C. et al. 2007. A new population of cells lacking expression of CD27 represents a notable component of the B cell memory compartment in systemic lupus erythematosus. J. Immunol. 178: 6624-6633.
-
(2007)
J. Immunol.
, vol.178
, pp. 6624-6633
-
-
Wei, C.1
-
118
-
-
4043164158
-
Human blood IgM "memory" B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoire
-
Weller, S. et al. 2004. Human blood IgM "memory" B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoire. Blood 104: 3647-3654.
-
(2004)
Blood
, vol.104
, pp. 3647-3654
-
-
Weller, S.1
-
119
-
-
0032528846
-
Absence of IgD-CD27(+) memory B cell population in X-linked hyper-IgM syndrome
-
Agematsu, K. et al. 1998. Absence of IgD-CD27(+) memory B cell population in X-linked hyper-IgM syndrome. J. Clin. Invest. 102: 853-860.
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 853-860
-
-
Agematsu, K.1
-
120
-
-
20444498902
-
Human intestinal IgA response is generated in the organized gut-associated lymphoid tissue but not in the lamina propria
-
Boursier, L. et al. 2005. Human intestinal IgA response is generated in the organized gut-associated lymphoid tissue but not in the lamina propria. Gastroenterology 128: 1879-1889.
-
(2005)
Gastroenterology
, vol.128
, pp. 1879-1889
-
-
Boursier, L.1
-
121
-
-
0034789991
-
Regulation of inherently autoreactive VH4-34 B cells in the maintenance of human B cell tolerance
-
Pugh-Bernard, A.E. et al. 2001. Regulation of inherently autoreactive VH4-34 B cells in the maintenance of human B cell tolerance. J. Clin. Invest. 108: 1061-1070.
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1061-1070
-
-
Pugh-Bernard, A.E.1
-
122
-
-
77956551877
-
High-throughput immunoglobulin repertoire analysis distinguishes between human IgM memory and switched memory B-cell populations
-
Wu, Y.C. et al. 2010. High-throughput immunoglobulin repertoire analysis distinguishes between human IgM memory and switched memory B-cell populations. Blood 116: 1070-1078.
-
(2010)
Blood
, vol.116
, pp. 1070-1078
-
-
Wu, Y.C.1
-
123
-
-
0030006070
-
Clonal selection and learning in the antibody system
-
Rajewsky, K. 1996. Clonal selection and learning in the antibody system. Nature 381: 751-758.
-
(1996)
Nature
, vol.381
, pp. 751-758
-
-
Rajewsky, K.1
-
124
-
-
0036785583
-
Evidence for involvement of a hydrophobic patch in framework region 1 of human V4-34-encoded Igs in recognition of the red blood cell I antigen
-
Potter, K.N. et al. 2002. Evidence for involvement of a hydrophobic patch in framework region 1 of human V4-34-encoded Igs in recognition of the red blood cell I antigen. J. Immunol. 169: 3777-3782.
-
(2002)
J. Immunol.
, vol.169
, pp. 3777-3782
-
-
Potter, K.N.1
-
125
-
-
0041689676
-
Predominant autoantibody production by early human B cell precursors
-
Wardemann, H. et al. 2003. Predominant autoantibody production by early human B cell precursors. Science 301: 1374-1377.
-
(2003)
Science
, vol.301
, pp. 1374-1377
-
-
Wardemann, H.1
-
126
-
-
66549118053
-
New insights into the regulation of human B-cell differentiation
-
Schmidlin, H., S.A. Diehl & B. Blom. 2009. New insights into the regulation of human B-cell differentiation. Trends Immunol. 30: 277-285.
-
(2009)
Trends Immunol.
, vol.30
, pp. 277-285
-
-
Schmidlin, H.1
Diehl, S.A.2
Blom, B.3
-
127
-
-
76149139419
-
B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans
-
Avery, D.T. et al. 2010. B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans. J. Exp. Med. 207: 155-171.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 155-171
-
-
Avery, D.T.1
-
128
-
-
29144519767
-
IL-21 induces differentiation of human naive and memory B cells into antibody-secreting plasma cells
-
Ettinger, R. et al. 2005. IL-21 induces differentiation of human naive and memory B cells into antibody-secreting plasma cells. J. Immunol. 175: 7867-7879.
-
(2005)
J. Immunol.
, vol.175
, pp. 7867-7879
-
-
Ettinger, R.1
-
129
-
-
6344269331
-
Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6
-
Ozaki, K. et al. 2004. Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6. J. Immunol. 173: 5361-5371.
-
(2004)
J. Immunol.
, vol.173
, pp. 5361-5371
-
-
Ozaki, K.1
-
130
-
-
44449145063
-
STAT3-mediated up-regulation of BLIMP1 is coordinated with BCL6 down-regulation to control human plasma cell differentiation
-
Diehl, S.A. et al. 2008. STAT3-mediated up-regulation of BLIMP1 is coordinated with BCL6 down-regulation to control human plasma cell differentiation. J. Immunol. 180: 4805-4815.
-
(2008)
J. Immunol.
, vol.180
, pp. 4805-4815
-
-
Diehl, S.A.1
-
131
-
-
79960372865
-
Sustained antibody responses depend on CD28 function in bone marrow-resident plasma cells
-
Rozanski, C.H. et al. 2011. Sustained antibody responses depend on CD28 function in bone marrow-resident plasma cells. J. Exp. Med. 208: 1435-1446.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 1435-1446
-
-
Rozanski, C.H.1
-
132
-
-
34249671217
-
CD28-mediated regulation of multiple myeloma cell proliferation and survival
-
Bahlis, N.J. et al. 2007. CD28-mediated regulation of multiple myeloma cell proliferation and survival. Blood 109: 5002-5010.
-
(2007)
Blood
, vol.109
, pp. 5002-5010
-
-
Bahlis, N.J.1
-
133
-
-
0034548453
-
The phosphatidylinositol 3-kinase/AKT kinase pathway in multiple myeloma plasma cells: roles in cytokine-dependent survival and proliferative responses
-
Tu, Y., A. Gardner & A. Lichtenstein. 2000. The phosphatidylinositol 3-kinase/AKT kinase pathway in multiple myeloma plasma cells: roles in cytokine-dependent survival and proliferative responses. Cancer Res. 60: 6763-6770.
-
(2000)
Cancer Res.
, vol.60
, pp. 6763-6770
-
-
Tu, Y.1
Gardner, A.2
Lichtenstein, A.3
-
134
-
-
77953191669
-
Circulating human B and plasma cells. Age-associated changes in counts and detailed characterization of circulating normal CD138- and CD138+ plasma cells
-
Caraux, A. et al. 2010. Circulating human B and plasma cells. Age-associated changes in counts and detailed characterization of circulating normal CD138- and CD138+ plasma cells. Haematologica 95: 1016-1020.
-
(2010)
Haematologica
, vol.95
, pp. 1016-1020
-
-
Caraux, A.1
-
135
-
-
63849146905
-
Blood-borne human plasma cells in steady state are derived from mucosal immune responses
-
Mei, H.E. et al. 2009. Blood-borne human plasma cells in steady state are derived from mucosal immune responses. Blood 113: 2461-2469.
-
(2009)
Blood
, vol.113
, pp. 2461-2469
-
-
Mei, H.E.1
-
136
-
-
13544251387
-
Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune response
-
Odendahl, M. et al. 2005. Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune response. Blood 105: 1614-1621.
-
(2005)
Blood
, vol.105
, pp. 1614-1621
-
-
Odendahl, M.1
-
137
-
-
77956571407
-
Human peripheral blood B-cell compartments: a crossroad in B-cell traffic
-
Perez-Andres, M. et al. 2010. Human peripheral blood B-cell compartments: a crossroad in B-cell traffic. Cytometry B Clin. Cytom. 78(Suppl 1): S47-S60.
-
(2010)
Cytometry B Clin. Cytom.
, vol.78
, Issue.SUPPL. 1
-
-
Perez-Andres, M.1
-
138
-
-
84255160948
-
B-cell replication history and somatic hypermutation status identify distinct pathophysiological backgrounds in common variable immunodeficiency
-
Epub ahead of print] PMID: 22042693.
-
Driessen, G.J. et al. 2011. B-cell replication history and somatic hypermutation status identify distinct pathophysiological backgrounds in common variable immunodeficiency. Blood [Epub ahead of print] PMID: 22042693. doi:.
-
(2011)
Blood
-
-
Driessen, G.J.1
|