The long isoform of terminal deoxynucleotidyl transferase enters the nucleus and, rather than catalyzing nontemplated nucleotide addition, modulates the catalytic activity of the short isoform

Journal of Experimental Medicine

Volumn 193, Issue 1, 2001, Pages 89-99

  Benedict, C L ^a   Gilfillan, S ^a   Kearney, J F ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Nontemplated regions; Phosphorylcholine; Terminal deoxynucleotidyl transferase; Terminal deoxynucleotidyl transferase isoforms; V(D)J rearrangements

Indexed keywords

DNA NUCLEOTIDYLEXOTRANSFERASE; NUCLEOTIDE; PHOSPHORYLCHOLINE; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; CATALYSIS; CELL NUCLEUS; GENE REARRANGEMENT; INTRON; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; TRANSGENE; TRANSGENIC MOUSE;

ALTERNATIVE SPLICING; ANIMALS; BASE SEQUENCE; CATALYSIS; CELL NUCLEUS; CLONING, MOLECULAR; DNA NUCLEOTIDYLEXOTRANSFERASE; DNA PRIMERS; DNA, COMPLEMENTARY; FETUS; GENE REARRANGEMENT, B-LYMPHOCYTE, HEAVY CHAIN; ISOENZYMES; LIVER; LYMPHOCYTES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, TRANSGENIC; NUCLEOTIDES;

EID: 0035180391     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.193.1.89     Document Type: Article

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