Efficient nuclear targeting of granzyme B and the nuclear consequences of apoptosis induced by granzyme B and perforin are caspase-dependent, but cell death is caspase-independent

Journal of Biological Chemistry

Volumn 273, Issue 43, 1998, Pages 27934-27938

  Trapani, Joseph A ^a   Jans, David A ^b   Jans, Patricia J ^b   Smyth, Mark J ^a   Browne, Kylie A ^a   Sutton, Vivien R ^a  

^a AUSTIN RESEARCH INSTITUTE   (Australia)

^b AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GRANZYME B; PERFORIN; PROTEIN KINASE;

APOPTOSIS; ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CYTOLYSIS; DNA STRAND BREAKAGE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; HOST RESISTANCE; HUMAN; HUMAN CELL; INFECTION RESISTANCE; PRIORITY JOURNAL; PROTEIN TARGETING; SIGNAL TRANSDUCTION;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; APOPTOSIS; BIOLOGICAL TRANSPORT; CASPASES; CELL MEMBRANE PERMEABILITY; CELL NUCLEUS; CYTOTOXICITY, IMMUNOLOGIC; DNA FRAGMENTATION; GRANZYMES; HUMANS; LYMPHOCYTES; MEMBRANE GLYCOPROTEINS; MICE; PORE FORMING CYTOTOXIC PROTEINS; SERINE ENDOPEPTIDASES;

EID: 0032561352     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.43.27934     Document Type: Article

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