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Volumn 275, Issue 50, 2000, Pages 39262-39266

Filamin (280-kDa actin-binding protein) is a caspase substrate and is also cleaved directly by the cytotoxic T lymphocyte protease granzyme B during apoptosis

(4) Browne, Kylie A a Johnstone, Ricky W a Jans, David A b Trapani, Joseph A a

a PETER MACCALLUM CANCER CENTRE (Australia)

b Biology and Environment (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN BINDING PROTEIN; CASPASE; CASPASE INHIBITOR; DNA FRAGMENT; FAS ANTIGEN; FILAMIN; GRANZYME B; KETONE DERIVATIVE; LYMPHOCYTE ANTIGEN RECEPTOR; PERFORIN; POLYPEPTIDE; PROTEINASE;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; MELANOMA CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; TARGET CELL;

AMINO ACID CHLOROMETHYL KETONES; ANTIGENS, CD95; APOPTOSIS; BINDING SITES; CASPASES; CELL MEMBRANE; CELL NUCLEUS; CELL SURVIVAL; CHROMIUM RADIOISOTOPES; CONTRACTILE PROTEINS; CYSTEINE PROTEINASE INHIBITORS; CYTOPLASM; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GRANZYMES; HUMANS; IN SITU NICK-END LABELING; JURKAT CELLS; LIGANDS; MEMBRANE GLYCOPROTEINS; MICROFILAMENT PROTEINS; PORE FORMING CYTOTOXIC PROTEINS; PRECIPITIN TESTS; SERINE ENDOPEPTIDASES; STAUROSPORINE; T-LYMPHOCYTES, CYTOTOXIC; TUMOR CELLS, CULTURED; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 0034671856 PISSN: 00219258 EISSN: None Source Type: Journal
DOI: 10.1074/jbc.C000622200 Document Type: Article

Times cited : (80)

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