Exploring the effect of mild hypothermia on CHO cell productivity

Biochemical Engineering Journal

Volumn 60, Issue , 2012, Pages 1-8

  Becerra, Silvana ^a   Berrios, Julio ^a   Osses, Nelson ^a   Altamirano, Claudia ^a  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE VALPARAÍSO   (Chile)

Author keywords

CHO cells culture; Mild hypothermia; Recombinant protein productivity

Indexed keywords

CELL LINES; CELLULAR PROCESS; CHO CELL; CULTURE TEMPERATURE; EFFECTS OF TEMPERATURE; EXPERIMENTAL APPROACHES; FED BATCHES; GENETIC MANIPULATIONS; HUMAN THERAPEUTICS; INCREASED PRODUCTIVITY; INDUSTRIAL SCALE; NET EFFECT; NEW STRATEGY; OPERATING CONDITION; PERFUSION CULTURES; PROTEIN SYNTHESIS; RECOMBINANT PROTEIN;

BIOSYNTHESIS; CELL GROWTH; CELLS; GROWTH KINETICS; HYPOTHERMIA; MOLECULAR BIOLOGY; PRODUCTIVITY; PROTEINS; TEMPERATURE;

CELL CULTURE;

MESSENGER RNA; RECOMBINANT PROTEIN;

APOPTOSIS; CELL CYCLE G1 PHASE; CELL GROWTH; CHO CELL; GENE EXPRESSION; HUMAN; HYPOTHERMIA; LOW TEMPERATURE; OVARY CELL CULTURE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; PROTEOMICS; REVIEW; TEMPERATURE SENSITIVITY; TRANSCRIPTOMICS; TRANSLATION REGULATION;

EID: 83555176235     PISSN: 1369703X     EISSN: 1873295X     Source Type: Journal    
DOI: 10.1016/j.bej.2011.10.003     Document Type: Review

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