Temperature reduction in cultures of hGM-CSF-expressing CHO cells: Effect on productivity and product quality

Biotechnology Progress

Volumn 21, Issue 1, 2005, Pages 17-21

  Bollati Fogolín, Mariela ^a,b   Forno, Guillermina ^a   Nimtz, Manfred ^b   Conradt, Harald S ^b   Etcheverrigaray, Marina ^a   Kratje, Ricardo ^a  

^a UNIVERSIDAD NACIONAL DEL LITORAL   (Argentina)

^b HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CHROMATOGRAPHIC ANALYSIS; GRANULAR MATERIALS; ION EXCHANGE; MASS SPECTROMETRY; METABOLISM; PROTEINS;

CELL METABOLISM; GLYCOSYLATION; GRANULAR MACROPHAGES; TERMINAL SIALYLATION;

BIOTECHNOLOGY;

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; LACTATE DEHYDROGENASE; RECOMBINANT PROTEIN;

ANIMAL; ARTICLE; BIOSYNTHESIS; CELL CULTURE; CELL SURVIVAL; CHO CELL; CULTURE TECHNIQUE; GLYCOSYLATION; HAMSTER; HUMAN; ISOLATION AND PURIFICATION; MASS SPECTROMETRY; METABOLISM; METHODOLOGY; PHYSIOLOGY; TEMPERATURE; TIME;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; CHO CELLS; CRICETINAE; CULTURE TECHNIQUES; GLYCOSYLATION; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; L-LACTATE DEHYDROGENASE; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TEMPERATURE; TIME FACTORS;

EID: 13544251527     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp049825t     Document Type: Article

References (20)

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