Functional proteomic analysis of GS-NS0 murine myeloma cell lines with varying recombinant monoclonal antibody production rate

Biotechnology and Bioengineering

Volumn 94, Issue 5, 2006, Pages 830-841

  Dinnis, Diane M ^a   Stansfield, Scott H ^a   Schlatter, Stefan ^a   Smales, C Mark ^b   Alete, Daniel ^b   Birch, John R ^c   Racher, Andrew J ^c   Marshall, Carol T ^d   Nielsen, Lars K ^a   James, David C ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b UNIVERSITY OF KENT   (United Kingdom)

^c LONZA AG   (Switzerland)

^d GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Cell specific production; Murine myeloma; Proteomics; Recombinant monoclonal antibody; Unfolded protein response

Indexed keywords

CELL MEMBRANES; ENZYME INHIBITION; MASS SPECTROMETRY; METABOLISM; MOLECULAR STRUCTURE; MONOCLONAL ANTIBODIES;

CELL-SPECIFIC PRODUCTION; MURINE MYELOMA; PROTEOMICS; RECOMBINANT MONOCLONAL ANTIBODY; UNFOLDED PROTEIN RESPONSE;

PROTEINS;

BINDING PROTEIN; CHAPERONE; CYTOSKELETON PROTEIN; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

ANIMAL CELL; ARTICLE; CELL FUNCTION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; IMMUNOBLOTTING; MASS SPECTROMETRY; MITOCHONDRION; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN FOLDING; PROTEOMICS; STATISTICAL ANALYSIS;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL LINE, TUMOR; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; MICE; MITOCHONDRIAL PROTEINS; MULTIPLE MYELOMA; MYELOMA PROTEINS; PROTEIN ENGINEERING; PROTEOME; RECOMBINANT PROTEINS;

MURINAE;

EID: 33746865348     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.20899     Document Type: Article

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