Characterization of novel peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) isoform in human liver

Journal of Biological Chemistry

Volumn 286, Issue 50, 2011, Pages 42923-42936

  Felder, Thomas K ^a   Soyal, Selma M ^a   Oberkofler, Hannes ^a   Hahne, Penelope ^a   Auer, Simon ^a   Weiss, Richard ^b   Gadermaier, Gabriele ^b   Miller, Karl ^c   Krempler, Franz ^c   Esterbauer, Harald ^d   Patsch, Wolfgang ^a  

^a PARACELSUS MEDICAL UNIVERSITY   (Austria)

^b UNIVERSITY OF SALZBURG   (Austria)

^c Krankenhaus Hallein   (Austria)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL PATHWAYS; CAMP-RESPONSE ELEMENT-BINDING PROTEINS; CO-ACTIVATION; COACTIVATORS; DATA SUPPORT; GLUCOCORTICOIDS; GLUCONEOGENESIS; HEPATIC TISSUE; HUMAN LIVER; ISOFORMS; METABOLIC PATHWAYS; MRNA LEVEL; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; POST-TRANSCRIPTIONAL; PROMOTER REGION; TRANSCRIPT LEVEL; TRANSCRIPTIONAL CO-ACTIVATORS; TRANSCRIPTIONAL PROGRAM; WILD TYPES;

AMINO ACIDS; METABOLISM; TISSUE;

CYTOLOGY;

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN A; GLUCOCORTICOID; GLUCOSE; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; TRANSCRIPTION FACTOR FKHR;

ADULT; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; FEMALE; GENE DELETION; GENETIC POLYMORPHISM; GLUCONEOGENESIS; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER PARENCHYMA; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; RAT; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; SPECIES DIFFERENCE; TISSUE SPECIFICITY; WILD TYPE;

8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ANIMALS; BLOTTING, NORTHERN; CHROMATIN IMMUNOPRECIPITATION; DEXAMETHASONE; FEMALE; GENE EXPRESSION; GENOTYPE; HEAT-SHOCK PROTEINS; HEP G2 CELLS; HUMANS; IMMUNOBLOTTING; LIVER; MICE; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; PROTEIN ISOFORMS; RATS; RNA, MESSENGER; TRANSCRIPTION FACTORS;

EID: 83355166925     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.227496     Document Type: Article

References (62)

1. Puigserver, P., Wu, Z., Park, C. W., Graves, R., Wright, M., and Spiegelman, B. M. (1998) Cell 92, 829-839
2. Wu, Z., Puigserver, P., Andersson, U., Zhang, C., Adelmant, G., Mootha, V., Troy, A., Cinti, S., Lowell, B., Scarpulla, R. C., and Spiegelman, B. M. (1999) Cell 98, 115-124
3. Lin, J., Wu, H., Tarr, P. T., Zhang, C. Y., Wu, Z., Boss, O., Michael, L. F., Puigserver, P., Isotani, E., Olson, E. N., Lowell, B. B., Bassel-Duby, R., and Spiegelman, B. M. (2002) Nature 418, 797-801
4. Handschin, C., Kobayashi, Y. M., Chin, S., Seale, P., Campbell, K. P., and Spiegelman, B. M. (2007) Genes Dev. 21, 770-783
5. Arany, Z., Foo, S. Y., Ma, Y., Ruas, J. L., Bommi-Reddy, A., Girnun, G., Cooper, M., Laznik, D., Chinsomboon, J., Rangwala, S. M., Baek, K. H., Rosenzweig, A., and Spiegelman, B. M. (2008) Nature 451, 1008-1012
6. Chinsomboon, J., Ruas, J., Gupta, R. K., Thom, R., Shoag, J., Rowe, G. C., Sawada, N., Raghuram, S., and Arany, Z. (2009) Proc. Natl. Acad. Sci. U.S.A. 106, 21401-21406
7. Herzig, S., Long, F., Jhala, U. S., Hedrick, S., Quinn, R., Bauer, A., Rudolph, D., Schutz, G., Yoon, C., Puigserver, P., Spiegelman, B., and Montminy, M. (2001) Nature 413, 179-183
8. Puigserver, P., Rhee, J., Donovan, J., Walkey, C. J., Yoon, J. C., Oriente, F., Kitamura, Y., Altomonte, J., Dong, H., Accili, D., and Spiegelman, B. M. (2003) Nature 423, 550-555
9. Yoon, J. C., Puigserver, P., Chen, G., Donovan, J., Wu, Z., Rhee, J., Adelmant, G., Stafford, J., Kahn, C. R., Granner, D. K., Newgard, C. B., and Spiegelman, B. M. (2001) Nature 413, 131-138
10. Vega, R. B., Huss, J. M., and Kelly, D. P. (2000) Mol. Cell. Biol. 20, 1868-1876
11. Liu, C., Li, S., Liu, T., Borjigin, J., and Lin, J. D. (2007) Nature 447, 477-481
12. St-Pierre, J., Drori, S., Uldry, M., Silvaggi, J. M., Rhee, J., Jäger, S., Handschin, C., Zheng, K., Lin, J., Yang, W., Simon, D. K., Bachoo, R., and Spiegelman, B. M. (2006) Cell 127, 397-408
13. Valle, I., Alvarez-Barrientos, A., Arza, E., Lamas, S., and Monsalve, M. (2005) Cardiovasc. Res. 66, 562-573
14. Finck, B. N., and Kelly, D. P. (2006) J. Clin. Investig. 116, 615-622
15. Handschin, C., and Spiegelman, B. M. (2006) Endocr. Rev. 27, 728-735
16. Soyal, S., Krempler, F., Oberkofler, H., and Patsch, W. (2006) Diabetologia 49, 1477-1488
17. Lin, J., Handschin, C., and Spiegelman, B. M. (2005) Cell Metab. 1, 361-370
18. Spiegelman, B. M., and Heinrich, R. (2004) Cell 119, 157-167
19. Chang, J. S., Huypens, P., Zhang, Y., Black, C., Kralli, A., and Gettys, T. W. (2010) J. Biol. Chem. 285, 18039-18050
20. Baar, K., Wende, A. R., Jones, T. E., Marison, M., Nolte, L. A., Chen, M., Kelly, D. P., and Holloszy, J. O. (2002) FASEB J. 16, 1879-1886
21. Miura, S., Kai, Y., Kamei, Y., and Ezaki, O. (2008) Endocrinology 149, 4527-4533
22. Zhang, Y., Huypens, P., Adamson, A. W., Chang, J. S., Henagan, T. M., Boudreau, A., Lenard, N. R., Burk, D., Klein, J., Perwitz, N., Shin, J., Fasshauer, M., Kralli, A., and Gettys, T. W. (2009) J. Biol. Chem. 284, 32813-32826
23. Mootha, V. K., Lindgren, C. M., Eriksson, K. F., Subramanian, A., Sihag, S., Lehar, J., Puigserver, P., Carlsson, E., Ridderstråle, M., Laurila, E., Houstis, N., Daly, M. J., Patterson, N., Mesirov, J. P., Golub, T. R., Tamayo, P., Spiegelman, B., Lander, E. S., Hirschhorn, J. N., Altshuler, D., and Groop, L. C. (2003) Nat. Genet. 34, 267-273
24. Patti, M. E., Butte, A. J., Crunkhorn, S., Cusi, K., Berria, R., Kashyap, S., Miyazaki, Y., Kohane, I., Costello, M., Saccone, R., Landaker, E. J., Goldfine, A. B., Mun, E., DeFronzo, R., Finlayson, J., Kahn, C. R., and Mandarino, L. J. (2003) Proc. Natl. Acad. Sci. U.S.A. 100, 8466-8471
25. Oberkofler, H., Linnemayr, V., Weitgasser, R., Klein, K., Xie, M., Iglseder, B., Krempler, F., Paulweber, B., and Patsch, W. (2004) Diabetes 53, 1385-1393
26. Cui, L., Jeong, H., Borovecki, F., Parkhurst, C. N., Tanese, N., and Krainc, D. (2006) Cell 127, 59-69
27. Weydt, P., Pineda, V. V., Torrence, A. E., Libby, R. T., Satterfield, T. F., Lazarowski, E. R., Gilbert, M. L., Morton, G. J., Bammler, T. K., Strand, A. D., Cui, L., Beyer, R. P., Easley, C. N., Smith, A. C., Krainc, D., Luquet, S., Sweet, I. R., Schwartz, M. W., and La Spada, A. R. (2006) Cell Metab. 4, 349-362
28. Weydt, P., Soyal, S. M., Gellera, C., Didonato, S., Weidinger, C., Oberkofler, H., Landwehrmeyer, G. B., and Patsch, W. (2009) Mol. Neurodegener. 4, 3
29. Felder, T. K., Hahne, P., Soyal, S. M., Miller, K., Höffinger, H., Oberkofler, H., Krempler, F., and Patsch, W. (2010) Int. J. Obes. 34, 846-851
30. Oberkofler, H., Schraml, E., Krempler, F., and Patsch, W. (2003) Biochem. J. 371, 89-96
31. Oberkofler, H., Esterbauer, H., Linnemayr, V., Strosberg, A. D., Krempler, F., and Patsch, W. (2002) J. Biol. Chem. 277, 16750-16757
32. Oberkofler, H., Hafner, M., Felder, T., Krempler, F., and Patsch, W. (2009) J. Mol. Med. 87, 299-306
33. Felder, T. K., Klein, K., Patsch, W., and Oberkofler, H. (2005) Biochim. Biophys. Acta 1731, 41-47
34. Hartl, A., Weiss, R., Hochreiter, R., Scheiblhofer, S., and Thalhamer, J. (2004) Methods 32, 328-339
35. Maruyama, K., and Sugano, S. (1994) Gene 138, 171-174
36. Esterbauer, H., Schneitler, C., Oberkofler, H., Ebenbichler, C., Paulweber, B., Sandhofer, F., Ladurner, G., Hell, E., Strosberg, A. D., Patsch, J. R., Krempler, F., and Patsch, W. (2001) Nat. Genet. 28, 178-183
37. Esterbauer, H., Oberkofler, H., Krempler, F., and Patsch, W. (1999) Genomics 62, 98-102
38. Hahne, P., Krempler, F., Schaap, F. G., Soyal, S. M., Höffinger, H., Miller, K., Oberkofler, H., Strobl, W., and Patsch, W. (2008) J. Intern. Med. 264, 452-462
39. Yamagata, K., Daitoku, H., Shimamoto, Y., Matsuzaki, H., Hirota, K., Ishida, J., and Fukamizu, A. (2004) J. Biol. Chem. 279, 23158-23165
40. Leitner, W. W., Seguin, M. C., Ballou, W. R., Seitz, J. P., Schultz, A. M., Sheehy, M. J., and Lyon, J. A. (1997) J. Immunol. 159, 6112-6119
41. Messeguer, X., Escudero, R., Farré, D., Núñez, O., Martínez, J., and Albà, M. M. (2002) Bioinformatics 18, 333-334
42. Loots, G. G., and Ovcharenko, I. (2004) Nucleic Acids Res. 32, W217-W221
43. Kakuma, T., Wang, Z. W., Pan, W., Unger, R. H., and Zhou, Y. T. (2000) Endocrinology 141, 4576-4582
44. Zhou, J., Febbraio, M., Wada, T., Zhai, Y., Kuruba, R., He, J., Lee, J. H., Khadem, S., Ren, S., Li, S., Silverstein, R. L., and Xie, W. (2008) Gastroenterology 134, 556-567
45. Gulick, T., Cresci, S., Caira, T., Moore, D. D., and Kelly, D. P. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 11012-11016
46. Rhee, J., Inoue, Y., Yoon, J. C., Puigserver, P., Fan, M., Gonzalez, F. J., and Spiegelman, B. M. (2003) Proc. Natl. Acad. Sci. U.S.A. 100, 4012-4017
47. Knutti, D., Kaul, A., and Kralli, A. (2000) Mol. Cell. Biol. 20, 2411-2422
48. Tcherepanova, I., Puigserver, P., Norris, J. D., Spiegelman, B. M., and McDonnell, D. P. (2000) J. Biol. Chem. 275, 16302-16308
49. Iyemere, V. P., Davies, N. H., and Brownlee, G. G. (1998) Nucleic Acids Res. 26, 2098-2104
50. Carninci, P., Sandelin, A., Lenhard, B., Katayama, S., Shimokawa, K., Ponjavic, J., Semple, C. A., Taylor, M. S., Engström, P. G., Frith, M. C., Forrest, A. R., Alkema, W. B., Tan, S. L., Plessy, C., Kodzius, R., Ravasi, T., Kasukawa, T., Fukuda, S., Kanamori-Katayama, M., Kitazume, Y., Kawaji, H., Kai, C., Nakamura, M., Konno, H., Nakano, K., Mottagui-Tabar, S., Arner, P., Chesi, A., Gustincich, S., Persichetti, F., Suzuki, H., Grimmond, S. M., Wells, C. A., Orlando, V., Wahlestedt, C., Liu, E. T., Harbers, M., Kawai, J., Bajic, V. B., Hume, D. A., and Hayashizaki, Y. (2006) Nat. Genet. 38, 626-635
51. Grosso, A. R., Gomes, A. Q., Barbosa-Morais, N. L., Caldeira, S., Thorne, N. P., Grech, G., von Lindern, M., and Carmo-Fonseca, M. (2008) Nucleic Acids Res. 36, 4823-4832
52. Goodrich, J. A., and Tjian, R. (2010) Nat. Rev. Genet. 11, 549-558
53. Lewis, B. P., Green, R. E., and Brenner, S. E. (2003) Proc. Natl. Acad. Sci. U.S.A. 100, 189-192
54. Sandelin, A., Carninci, P., Lenhard, B., Ponjavic, J., Hayashizaki, Y., and Hume, D. A. (2007) Nat. Rev. Genet. 8, 424-436
55. Puigserver, P., Adelmant, G., Wu, Z., Fan, M., Xu, J., O'Malley, B., and Spiegelman, B. M. (1999) Science 286, 1368-1371
56. Lerin, C., Rodgers, J. T., Kalume, D. E., Kim, S. H., Pandey, A., and Puigserver, P. (2006) Cell Metab. 3, 429-438
57. Rha, G. B., Wu, G., Shoelson, S. E., and Chi, Y. I. (2009) J. Biol. Chem. 284, 35165-35176
58. Knutti, D., Kressler, D., and Kralli, A. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 9713-9718
59. Fan, M., Rhee, J., St-Pierre, J., Handschin, C., Puigserver, P., Lin, J., Jäeger, S., Erdjument-Bromage, H., Tempst, P., and Spiegelman, B. M. (2004) Genes Dev. 18, 278-289
60. Lin, J., Wu, P. H., Tarr, P. T., Lindenberg, K. S., St-Pierre, J., Zhang, C. Y., Mootha, V. K., Jäger, S., Vianna, C. R., Reznick, R. M., Cui, L., Manieri, M., Donovan, M. X., Wu, Z., Cooper, M. P., Fan, M. C., Rohas, L. M., Zavacki, A. M., Cinti, S., Shulman, G. I., Lowell, B. B., Krainc, D., and Spiegelman, B. M. (2004) Cell 119, 121-135
61. Rodgers, J. T., Lerin, C., Haas, W., Gygi, S. P., Spiegelman, B. M., and Puigserver, P. (2005) Nature 434, 113-118
62. Crooks, G. E., Hon, G., Chandonia, J. M., and Brenner, S. E. (2004) Genome Res. 14, 1188-1190