-
1
-
-
79751531393
-
Heart disease and stroke statistics-2011 update: A report from the american heart association
-
Roger VL, Go AS, Lloyd-Jones DM, Adams RJ, Berry JD, Brown TM, et al. Heart disease and stroke statistics-2011 update: a report from the American Heart Association. Circulation 2011; 123: e18-e209.
-
(2011)
Circulation
, vol.123
-
-
Roger, V.L.1
Go, A.S.2
Lloyd-Jones, D.M.3
Adams, R.J.4
Berry, J.D.5
Brown, T.M.6
-
2
-
-
0028783948
-
The national institute of neurological disorders and stroke rt-pa stroke study group
-
Tissue plasminogen activator for acute ischemic stroke.
-
Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. N Engl J Med 1995; 333: 1581-7.
-
(1995)
N. Engl. J. Med.
, vol.333
, pp. 1581-1587
-
-
-
3
-
-
68749100878
-
Expansion of the time window for treatment of acute ischemic stroke with intravenous tissue plasminogen activator: A science advisory from the american heart association/american stroke association
-
Del Zoppo GJ, Saver JL, Jauch EC, Adams HP Jr. Expansion of the time window for treatment of acute ischemic stroke with intravenous tissue plasminogen activator: a science advisory from the American Heart Association/American Stroke Association. Stroke 2009; 40: 2945-8.
-
(2009)
Stroke
, vol.40
, pp. 2945-2948
-
-
Del Zoppo, G.J.1
Saver, J.L.2
Jauch, E.C.3
Adams Jr., H.P.4
-
4
-
-
0035942340
-
Why are stroke patients excluded from TPA therapy? An analysis of patient eligibility
-
Barber PA, Zhang J, Demchuk AM, Hill MD, Buchan AM. Why are stroke patients excluded from TPA therapy? An analysis of patient eligibility. Neurology 2001; 56: 1015-20. (Pubitemid 32336306)
-
(2001)
Neurology
, vol.56
, Issue.8
, pp. 1015-1020
-
-
Barber, P.A.1
Zhang, J.2
Demchuk, A.M.3
Hill, M.D.4
Buchan, A.M.5
-
5
-
-
41249090658
-
National US estimates of recombinant tissue plasminogen activator use: ICD-9 codes substantially underestimate
-
DOI 10.1161/STROKEAHA.107.490375
-
Kleindorfer D, Lindsell CJ, Brass L, Koroshetz W, Broderick JP. National US estimates of recombinant tissue plasminogen activator use: ICD-9 codes substantially underestimate. Stroke 2008; 39: 924-8. (Pubitemid 351619542)
-
(2008)
Stroke
, vol.39
, Issue.3
, pp. 924-928
-
-
Kleindorfer, D.1
Lindsell, C.J.2
Brass, L.3
Koroshetz, W.4
Broderick, J.P.5
-
6
-
-
78649906075
-
Neurocognitive and neuroimaging predictors of clinical outcome in bipolar disorder
-
Bearden CE, Woogen M, Glahn DC. Neurocognitive and neuroimaging predictors of clinical outcome in bipolar disorder. Curr Psychiatry Rep 2010; 12: 499-504.
-
(2010)
Curr. Psychiatry Rep.
, vol.12
, pp. 499-504
-
-
Bearden, C.E.1
Woogen, M.2
Glahn, D.C.3
-
7
-
-
9744238838
-
Neuroprotective and neurotrophic actions of the mood stabilizer lithium: can it be used to treat neurodegenerative diseases
-
Chuang DM. Neuroprotective and neurotrophic actions of the mood stabilizer lithium: can it be used to treat neurodegenerative diseases? Crit Rev Neurobiol 2004; 16: 83-90.
-
(2004)
Crit. Rev. Neurobiol.
, vol.16
, pp. 83-90
-
-
Chuang, D.M.1
-
8
-
-
28844475505
-
The antiapoptotic actions of mood stabilizers: Molecular mechanisms and therapeutic potentials
-
Chuang DM. The antiapoptotic actions of mood stabilizers: molecular mechanisms and therapeutic potentials. Ann N Y Acad Sci 2005; 1053: 195-204.
-
(2005)
Ann .N. Y. Acad. Sci.
, vol.1053
, pp. 195-204
-
-
Chuang, D.M.1
-
9
-
-
0035034203
-
The cellular neurobiology of depression
-
DOI 10.1038/87865
-
Manji HK, Drevets WC, Charney DS. The cellular neurobiology of depression. Nat Med 2001; 7: 541-7. (Pubitemid 32448319)
-
(2001)
Nature Medicine
, vol.7
, Issue.5
, pp. 541-547
-
-
Manji, H.K.1
Drevets, W.C.2
Charney, D.S.3
-
10
-
-
34250222104
-
In Search of the Holy Grail for the Treatment of Neurodegenerative Disorders: Has a Simple Cation Been Overlooked?
-
DOI 10.1016/j.biopsych.2007.04.008, PII S0006322307003484
-
Chuang DM, Manji HK. In search of the Holy Grail for the treatment of neurodegenerative disorders: has a simple cation been overlooked? Biol Psychiatry 2007; 62: 4-6. (Pubitemid 46898231)
-
(2007)
Biological Psychiatry
, vol.62
, Issue.1
, pp. 4-6
-
-
Chuang, D.-M.1
Manji, H.K.2
-
11
-
-
0034619037
-
Lithium-induced increase in human brain grey matter
-
Moore GJ, Bebchuk JM, Wilds IB, Chen G, Manji HK. Lithium-induced increase in human brain grey matter. Lancet 2000; 356: 1241-2.
-
(2000)
Lancet
, vol.356
, pp. 1241-1242
-
-
Moore, G.J.1
Bebchuk, J.M.2
Wilds, I.B.3
Chen, G.4
Manji, H.K.5
-
12
-
-
34247880408
-
Cingulate gyrus volumetry in drug free bipolar patients and patients treated with valproate or valproate and quetiapine
-
DOI 10.1016/j.jpsychires.2006.07.006, PII S0022395606001427
-
Atmaca M, Ozdemir H, Cetinkaya S, Parmaksiz S, Belli H, Poyraz AK, et al. Cingulate gyrus volumetry in drug free bipolar patients and patients treated with valproate or valproate and quetiapine. J Psychiatr Res 2007; 41: 821-7. (Pubitemid 46693892)
-
(2007)
Journal of Psychiatric Research
, vol.41
, Issue.10
, pp. 821-827
-
-
Atmaca, M.1
Ozdemir, H.2
Cetinkaya, S.3
Parmaksiz, S.4
Belli, H.5
Kursad Poyraz, A.6
Tezcan, E.7
Ogur, E.8
-
13
-
-
77957019846
-
Molecular actions and therapeutic potential of lithium in preclinical and clinical studies of CNS disorders
-
Chiu CT, Chuang DM. Molecular actions and therapeutic potential of lithium in preclinical and clinical studies of CNS disorders. Pharmacol Ther 2010; 128: 281-304.
-
(2010)
Pharmacol. Ther.
, vol.128
, pp. 281-304
-
-
Chiu, C.T.1
Chuang, D.M.2
-
14
-
-
70350018325
-
Multiple roles of HDAC inhibition in neurodegenerative conditions
-
Chuang DM, Leng Y, Marinova Z, Kim HJ, Chiu CT. Multiple roles of HDAC inhibition in neurodegenerative conditions. Trends Neurosci 2009; 32: 591-601.
-
(2009)
Trends. Neurosci.
, vol.32
, pp. 591-601
-
-
Chuang, D.M.1
Leng, Y.2
Marinova, Z.3
Kim, H.J.4
Chiu, C.T.5
-
15
-
-
77949300922
-
Voltagegated sodium channels as therapeutic targets in epilepsy and other neurological disorders
-
Mantegazza M, Curia G, Biagini G, Ragsdale DS, Avoli M. Voltagegated sodium channels as therapeutic targets in epilepsy and other neurological disorders. Lancet Neurol 2010; 9: 413-24.
-
(2010)
Lancet Neurol.
, vol.9
, pp. 413-424
-
-
Mantegazza, M.1
Curia, G.2
Biagini, G.3
Ragsdale, D.S.4
Avoli, M.5
-
16
-
-
77952675659
-
Pathophysiologic mechanisms of acute ischemic stroke: An overview with emphasis on therapeutic significance beyond thrombolysis
-
Deb P, Sharma S, Hassan KM. Pathophysiologic mechanisms of acute ischemic stroke: An overview with emphasis on therapeutic significance beyond thrombolysis. Pathophysiology 2010; 17: 197-218.
-
(2010)
Pathophysiology
, vol.17
, pp. 197-218
-
-
Deb, P.1
Sharma, S.2
Hassan, K.M.3
-
17
-
-
77449152992
-
Oxidative stress and its role in the pathogenesis of ischaemic stroke
-
Allen CL, Bayraktutan U. Oxidative stress and its role in the pathogenesis of ischaemic stroke. Int J Stroke 2009; 4: 461-70.
-
(2009)
Int. J. Stroke
, vol.4
, pp. 461-470
-
-
Allen, C.L.1
Bayraktutan, U.2
-
18
-
-
0018318787
-
Brain edema during ischemia and after restoration of blood flow. Measurement of water, sodium, potassium content and plasma protein permeability
-
Ito U, Ohno K, Nakamura R, Suganuma F, Inaba Y. Brain edema during ischemia and after restoration of blood flow. Measurement of water, sodium, potassium content and plasma protein permeability. Stroke 1979; 10: 542-7. (Pubitemid 9256246)
-
(1979)
Stroke
, vol.10
, Issue.5
, pp. 542-547
-
-
Ito, U.1
Ohno, K.2
Nakamura, R.3
-
19
-
-
0035143182
-
Cerebral ischemia and inflammation
-
DOI 10.1097/00019052-200102000-00014
-
Iadecola C, Alexander M. Cerebral ischemia and inflammation. Curr Opin Neurol 2001; 14: 89-94. (Pubitemid 32116263)
-
(2001)
Current Opinion in Neurology
, vol.14
, Issue.1
, pp. 89-94
-
-
Iadecola, C.1
Alexander, M.2
-
20
-
-
33847644971
-
The inflammatory response in stroke
-
DOI 10.1016/j.jneuroim.2006.11.014, PII S0165572806004693, Inflammation, Neurodegeneration and Neuroprotection in the Central Nervous System
-
Wang Q, Tang XN, Yenari MA. The inflammatory response in stroke. J Neuroimmunol 2007; 184: 53-68. (Pubitemid 46365991)
-
(2007)
Journal of Neuroimmunology
, vol.184
, Issue.1-2
, pp. 53-68
-
-
Wang, Q.1
Tang, X.N.2
Yenari, M.A.3
-
22
-
-
0028308758
-
Influx of leukocytes and platelets in an evolving brain infarct (Wistar rat)
-
Garcia JH, Liu KF, Yoshida Y, Lian J, Chen S, del Zoppo GJ. Influx of leukocytes and platelets in an evolving brain infarct (Wistar rat). Am J Pathol 1994; 144: 188-99. (Pubitemid 24158372)
-
(1994)
American Journal of Pathology
, vol.144
, Issue.1
, pp. 188-199
-
-
Garcia, J.H.1
Liu, K.F.2
Yoshida, Y.3
Lian, J.4
Chen, S.5
Del Zoppo, G.J.6
-
23
-
-
0042190147
-
Microglial activation precedes and predominates over macrophage infiltration in transient focal cerebral ischemia: A study in green fluorescent protein transgenic bone marrow chimeric mice
-
DOI 10.1016/S0014-4886(03)00082-7
-
Schilling M, Besselmann M, Leonhard C, Mueller M, Ringelstein EB, Kiefer R. Microglial activation precedes and predominates over macrophage infiltration in transient focal cerebral ischemia: a study in green fluorescent protein transgenic bone marrow chimeric mice. Exp Neurol 2003; 183: 25-33. (Pubitemid 37075853)
-
(2003)
Experimental Neurology
, vol.183
, Issue.1
, pp. 25-33
-
-
Schilling, M.1
Besselmann, M.2
Leonhard, C.3
Mueller, M.4
Ringelstein, E.B.5
Kiefer, R.6
-
24
-
-
0031025503
-
Temporal profile of microglial response following transient (2 h) middle cerebral artery occlusion
-
DOI 10.1016/S0006-8993(96)01085-2, PII S0006899396010852
-
Zhang Z, Chopp M, Powers C. Temporal profile of microglial response following transient (2 h) middle cerebral artery occlusion. Brain Res 1997; 744: 189-98. (Pubitemid 27032335)
-
(1997)
Brain Research
, vol.744
, Issue.2
, pp. 189-198
-
-
Zhang, Z.1
Chopp, M.2
Powers, C.3
-
25
-
-
0035153212
-
Immune function of astrocytes
-
DOI 10.1002/glia.1107
-
Dong Y, Benveniste EN. Immune function of astrocytes. Glia 2001; 36: 180-90. (Pubitemid 33055906)
-
(2001)
GLIA
, vol.36
, Issue.2
, pp. 180-190
-
-
Dong, Y.1
Benveniste, E.N.2
-
26
-
-
53749096762
-
Blood-brain barrier tight junction permeability and ischemic stroke
-
Sandoval KE, Witt KA. Blood-brain barrier tight junction permeability and ischemic stroke. Neurobiol Dis 2008; 32: 200-19.
-
(2008)
Neurobiol. Dis.
, vol.32
, pp. 200-219
-
-
Sandoval, K.E.1
Witt, K.A.2
-
27
-
-
34547645047
-
Modelling of the blood - Brain barrier in drug discovery and development
-
DOI 10.1038/nrd2368, PII NRD2368
-
Cecchelli R, Berezowski V, Lundquist S, Culot M, Renftel M, Dehouck MP, et al. Modelling of the blood-brain barrier in drug discovery and development. Nat Rev Drug Discov 2007; 6: 650-61. (Pubitemid 47202487)
-
(2007)
Nature Reviews Drug Discovery
, vol.6
, Issue.8
, pp. 650-661
-
-
Cecchelli, R.1
Berezowski, V.2
Lundquist, S.3
Culot, M.4
Renftel, M.5
Dehouck, M.-P.6
Fenart, L.7
-
28
-
-
38749096624
-
Multiphasic roles for matrix metalloproteinases after stroke
-
Rosell A, Lo EH. Multiphasic roles for matrix metalloproteinases after stroke. Curr Opin Pharmacol 2008; 8: 82-9.
-
(2008)
Curr. Opin. Pharmacol.
, vol.8
, pp. 82-89
-
-
Rosell, A.1
Lo, E.H.2
-
29
-
-
0029864714
-
Proteolytic cascade enzymes increase in focal cerebral ischemia in rat
-
Rosenberg GA, Navratil M, Barone F, Feuerstein G. Proteolytic cascade enzymes increase in focal cerebral ischemia in rat. J Cereb Blood Flow Metab 1996; 16: 360-6. (Pubitemid 26125324)
-
(1996)
Journal of Cerebral Blood Flow and Metabolism
, vol.16
, Issue.3
, pp. 360-366
-
-
Rosenberg, G.A.1
Navratil, M.2
Barone, F.3
Feuerstein, G.4
-
30
-
-
0033581392
-
Early appearance of activated matrix metalloproteinase-9 and blood-brain barrier disruption in mice after focal cerebral ischemia and reperfusion
-
DOI 10.1016/S0006-8993(99)01843-0, PII S0006899399018430
-
Fujimura M, Gasche Y, Morita-Fujimura Y, Massengale J, Kawase M, Chan PH. Early appearance of activated matrix metalloproteinase-9 and blood-brain barrier disruption in mice after focal cerebral ischemia and reperfusion. Brain Res 1999; 842: 92-100. (Pubitemid 29447856)
-
(1999)
Brain Research
, vol.842
, Issue.1
, pp. 92-100
-
-
Fujimura, M.1
Gasche, Y.2
Morita-Fujimura, Y.3
Massengale, J.4
Kawase, M.5
Chan, P.H.6
-
31
-
-
0005728038
-
Matrix metalloproteinases increase very early during experimental focal cerebral ischemia
-
Heo JH, Lucero J, Abumiya T, Koziol JA, Copeland BR, del Zoppo GJ. Matrix metalloproteinases increase very early during experimental focal cerebral ischemia. J Cereb Blood Flow Metab 1999; 19: 624-33. (Pubitemid 30161214)
-
(1999)
Journal of Cerebral Blood Flow and Metabolism
, vol.19
, Issue.6
, pp. 624-633
-
-
Heo, J.H.1
Lucero, J.2
Abumiya, T.3
Koziol, J.A.4
Copeland, B.R.5
Del Zoppo, G.J.6
-
32
-
-
68749114038
-
Plasma and brain matrix metalloproteinase-9 after acute focal cerebral ischemia in rats
-
Park KP, Rosell A, Foerch C, Xing C, Kim WJ, Lee S, et al. Plasma and brain matrix metalloproteinase-9 after acute focal cerebral ischemia in rats. Stroke 2009; 40: 2836-42.
-
(2009)
Stroke
, vol.40
, pp. 2836-2842
-
-
Park, K.P.1
Rosell, A.2
Foerch, C.3
Xing, C.4
Kim, W.J.5
Lee, S.6
-
33
-
-
77649125731
-
Blood-brain barrier disruption in humans is independently associated with increased matrix metalloproteinase-9
-
Barr TL, Latour LL, Lee KY, Schaewe TJ, Luby M, Chang GS, et al. Blood-brain barrier disruption in humans is independently associated with increased matrix metalloproteinase-9. Stroke 2010; 41: e123-8.
-
(2010)
Stroke
, vol.41
-
-
Barr, T.L.1
Latour, L.L.2
Lee, K.Y.3
Schaewe, T.J.4
Luby, M.5
Chang, G.S.6
-
34
-
-
41149090849
-
MMP-9-positive neutrophil infiltration is associated to blood-brain barrier breakdown and basal lamina type IV collagen degradation during hemorrhagic transformation after human ischemic stroke
-
DOI 10.1161/STROKEAHA.107.500868, PII 0000767020080400000013
-
Rosell A, Cuadrado E, Ortega-Aznar A, Hernandez-Guillamon M, Lo EH, Montaner J. MMP-9-positive neutrophil infiltration is associated to blood-brain barrier breakdown and basal lamina type IV collagen degradation during hemorrhagic transformation after human ischemic stroke. Stroke 2008; 39: 1121-6. (Pubitemid 351440679)
-
(2008)
Stroke
, vol.39
, Issue.4
, pp. 1121-1126
-
-
Rosell, A.1
Cuadrado, E.2
Ortega-Aznar, A.3
Hernandez-Guillamon, M.4
Lo, E.H.5
Montaner, J.6
-
35
-
-
0035478029
-
Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia
-
Asahi M, Wang X, Mori T, Sumii T, Jung JC, Moskowitz MA, et al. Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia. J Neurosci 2001; 21: 7724-32. (Pubitemid 32904971)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.19
, pp. 7724-7732
-
-
Asahi, M.1
Wang, X.2
Mori, T.3
Sumii, T.4
Jung, J.-C.5
Moskowitz, M.A.6
Fini, M.E.7
Lo, E.H.8
-
36
-
-
33947493391
-
Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat
-
DOI 10.1038/sj.jcbfm.9600375, PII 9600375
-
Yang Y, Estrada EY, Thompson JF, Liu W, Rosenberg GA. Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat. J Cereb Blood Flow Metab 2007; 27: 697-709. (Pubitemid 46474608)
-
(2007)
Journal of Cerebral Blood Flow and Metabolism
, vol.27
, Issue.4
, pp. 697-709
-
-
Yang, Y.1
Estrada, E.Y.2
Thompson, J.F.3
Liu, W.4
Rosenberg, G.A.5
-
37
-
-
43249116466
-
A new penumbra: Transitioning from injury into repair after stroke
-
DOI 10.1038/nm1735, PII NM1735
-
Lo EH. A new penumbra: transitioning from injury into repair after stroke. Nat Med 2008; 14: 497-500. (Pubitemid 351655209)
-
(2008)
Nature Medicine
, vol.14
, Issue.5
, pp. 497-500
-
-
Lo, E.H.1
-
38
-
-
35848949798
-
Cellcell signaling in the neurovascular unit
-
Lok J, Gupta P, Guo S, Kim WJ, Whalen MJ, van Leyen K, et al. Cellcell signaling in the neurovascular unit. Neurochem Res 2007; 32: 2032-45.
-
(2007)
Neurochem. Res.
, vol.32
, pp. 2032-2045
-
-
Lok, J.1
Gupta, P.2
Guo, S.3
Kim, W.J.4
Whalen, M.J.5
Van Leyen, K.6
-
39
-
-
1842586163
-
Post-ischemic Administration of Heparin-Binding Epidermal Growth Factor-like Growth Factor (HB-EGF) Reduces Infarct Size and Modifies Neurogenesis after Focal Cerebral Ischemia in the Rat
-
Jin K, Sun Y, Xie L, Childs J, Mao XO, Greenberg DA. Post-ischemic administration of heparin-binding epidermal growth factor-like growth factor (HB-EGF) reduces infarct size and modifies neurogenesis after focal cerebral ischemia in the rat. J Cereb Blood Flow Metab 2004; 24: 399-408. (Pubitemid 38452231)
-
(2004)
Journal of Cerebral Blood Flow and Metabolism
, vol.24
, Issue.4
, pp. 399-408
-
-
Jin, K.1
Sun, Y.2
Xie, L.3
Childs, J.4
Mao, X.O.5
Greenberg, D.A.6
-
40
-
-
0038443056
-
Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke
-
DOI 10.1002/ana.10555
-
Chen J, Zhang ZG, Li Y, Wang Y, Wang L, Jiang H, et al. Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke. Ann Neurol 2003; 53: 743-51. (Pubitemid 36622511)
-
(2003)
Annals of Neurology
, vol.53
, Issue.6
, pp. 743-751
-
-
Chen, J.1
Zhang, Z.G.2
Li, Y.3
Wang, Y.4
Wang, L.5
Jiang, H.6
Zhang, C.7
Lu, M.8
Katakowski, M.9
Feldkamp, C.S.10
Chopp, M.11
-
41
-
-
3042688444
-
Treatment of stroke with erythropoietin enhances neurogenesis and angiogenesis and improves neurological function in rats
-
DOI 10.1161/01.STR.0000132196.49028.a4
-
Wang L, Zhang Z, Wang Y, Zhang R, Chopp M. Treatment of stroke with erythropoietin enhances neurogenesis and angiogenesis and improves neurological function in rats. Stroke 2004; 35: 1732-7. (Pubitemid 38823656)
-
(2004)
Stroke
, vol.35
, Issue.7
, pp. 1732-1737
-
-
Wang, L.1
Zhang, Z.2
Wang, Y.3
Zhang, R.4
Chopp, M.5
-
42
-
-
0033797255
-
VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain
-
Zhang ZG, Zhang L, Jiang Q, Zhang R, Davies K, Powers C, et al. VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain. J Clin Invest 2000; 106: 829-38.
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 829-838
-
-
Zhang, Z.G.1
Zhang, L.2
Jiang, Q.3
Zhang, R.4
Davies, K.5
Powers, C.6
-
43
-
-
4344639706
-
Targets for vascular protection after acute ischemic stroke
-
DOI 10.1161/01.STR.0000138023.60272.9e
-
Fagan SC, Hess DC, Hohnadel EJ, Pollock DM, Ergul A. Targets for vascular protection after acute ischemic stroke. Stroke 2004; 35: 2220-5. (Pubitemid 39129589)
-
(2004)
Stroke
, vol.35
, Issue.9
, pp. 2220-2225
-
-
Fagan, S.C.1
Hess, D.C.2
Hohnadel, E.J.3
Pollock, D.M.4
Ergul, A.5
-
44
-
-
56449097523
-
Vascular endothelial growth factor and angiopoietins in neurovascular regeneration and protection following stroke
-
Hansen TM, Moss AJ, Brindle NP. Vascular endothelial growth factor and angiopoietins in neurovascular regeneration and protection following stroke. Curr Neurovasc Res 2008; 5: 236-45.
-
(2008)
Curr. Neurovasc. Res.
, vol.5
, pp. 236-245
-
-
Hansen, T.M.1
Moss, A.J.2
Brindle, N.P.3
-
45
-
-
22344437713
-
Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors
-
Lee S, Jilani SM, Nikolova GV, Carpizo D, Iruela-Arispe ML. Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors. J Cell Biol 2005; 169: 681-91.
-
(2005)
J. Cell Biol.
, vol.169
, pp. 681-961
-
-
Lee, S.1
Jilani, S.M.2
Nikolova, G.V.3
Carpizo, D.4
Iruela-Arispe, M.L.5
-
46
-
-
33645744014
-
Role of matrix metalloproteinases in delayed cortical responses after stroke
-
Zhao BQ, Wang S, Kim HY, Storrie H, Rosen BR, Mooney DJ, et al. Role of matrix metalloproteinases in delayed cortical responses after stroke. Nat Med 2006; 12: 441-5.
-
(2006)
Nat. Med.
, vol.12
, pp. 441-445
-
-
Zhao, B.Q.1
Wang, S.2
Kim, H.Y.3
Storrie, H.4
Rosen, B.R.5
Mooney, D.J.6
-
47
-
-
0032557889
-
Neuroprotective effects of chronic lithium on focal cerebral ischemia in rats
-
Nonaka S, Chuang DM. Neuroprotective effects of chronic lithium on focal cerebral ischemia in rats. Neuroreport 1998; 9: 2081-4. (Pubitemid 28300570)
-
(1998)
NeuroReport
, vol.9
, Issue.9
, pp. 2081-2084
-
-
Nonaka, S.1
Chuang, D.-M.2
-
48
-
-
36348970682
-
Lithium reduces ischemia-induced hippocampal CA1 damage and behavioral deficits in gerbils
-
DOI 10.1016/j.brainres.2007.09.054, PII S0006899307022299
-
Bian Q, Shi T, Chuang DM, Qian Y. Lithium reduces ischemiainduced hippocampal CA1 damage and behavioral deficits in gerbils. Brain Res 2007; 1184: 270-6. (Pubitemid 350160570)
-
(2007)
Brain Research
, vol.1184
, Issue.1
, pp. 270-276
-
-
Bian, Q.1
Shi, T.2
Chuang, D.-M.3
Qian, Y.4
-
49
-
-
0037609376
-
Postinsult treatment with lithium reduces brain damage and facilitates neurological recovery in a rat ischemia/reperfusion model
-
U S A
-
Ren M, Senatorov VV, Chen RW, Chuang DM. Postinsult treatment with lithium reduces brain damage and facilitates neurological recovery in a rat ischemia/reperfusion model. Proc Natl Acad Sci U S A 2003; 100: 6210-5.
-
(2003)
Proc. Natl. Acad. Sci.
, vol.100
, pp. 6210-625
-
-
Ren, M.1
Senatorov, V.V.2
Chen, R.W.3
Chuang, D.M.4
-
51
-
-
0030449964
-
Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells
-
Stambolic V, Ruel L, Woodgett JR. Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells. Curr Biol 1996; 6: 1664-8. (Pubitemid 27050234)
-
(1996)
Current Biology
, vol.6
, Issue.12
, pp. 1664-1668
-
-
Stambolic, V.1
Ruel, L.2
Woodgett, J.R.3
-
52
-
-
0042379932
-
Lithium and GSK-3: One inhibitor, two inhibitory actions, multiple outcomes
-
DOI 10.1016/S0165-6147(03)00206-2
-
Jope RS. Lithium and GSK-3: one inhibitor, two inhibitory actions, multiple outcomes. Trends Pharmacol Sci 2003; 24: 441-3. (Pubitemid 37088166)
-
(2003)
Trends in Pharmacological Sciences
, vol.24
, Issue.9
, pp. 441-443
-
-
Jope, R.S.1
-
53
-
-
0034805180
-
Lithium inhibits glycogen synthase kinase-3 by competition for magnesium
-
DOI 10.1006/bbrc.2000.4169
-
Ryves WJ, Harwood AJ. Lithium inhibits glycogen synthase kinase-3 by competition for magnesium. Biochem Biophys Res Commun 2001; 280: 720-5. (Pubitemid 32924489)
-
(2001)
Biochemical and Biophysical Research Communications
, vol.280
, Issue.3
, pp. 720-725
-
-
Ryves, W.J.1
Harwood, A.J.2
-
54
-
-
82955196366
-
GSK-3 as a target for lithium-induced neuroprotection against excitotoxicity in neuronal cultures and animal models of ischemic stroke
-
Chuang DM, Wang Z, Chiu CT. GSK-3 as a target for lithium-induced neuroprotection against excitotoxicity in neuronal cultures and animal models of ischemic stroke. Front Mol Neurosci 2011; 4: 15.
-
(2011)
Front. Mol. Neurosci.
, vol.4
, pp. 15
-
-
Chuang, D.M.1
Wang, Z.2
Chiu, C.T.3
-
55
-
-
0030723121
-
Lithium increases transcription factor binding to AP-1 and cyclic AMP- responsive element in cultured neurons and rat brain
-
Ozaki N, Chuang DM. Lithium increases transcription factor binding to AP-1 and cyclic AMP-responsive element in cultured neurons and rat brain. J Neurochem 1997; 69: 2336-44. (Pubitemid 27495418)
-
(1997)
Journal of Neurochemistry
, vol.69
, Issue.6
, pp. 2336-2344
-
-
Ozaki, N.1
Chuang, D.-M.2
-
56
-
-
0037314543
-
Regulation of c-Jun N-terminal kinase, p38 kinase and AP-1 DNA binding in cultured brain neurons: Roles in glutamate excitotoxicity and lithium neuroprotection
-
DOI 10.1046/j.1471-4159.2003.01548.x
-
Chen RW, Qin ZH, Ren M, Kanai H, Chalecka-Franaszek E, Leeds P, et al. Regulation of c-Jun N-terminal kinase, p38 kinase and AP-1 DNA binding in cultured brain neurons: roles in glutamate excitotoxicity and lithium neuroprotection. J Neurochem 2003; 84: 566-75. (Pubitemid 36182255)
-
(2003)
Journal of Neurochemistry
, vol.84
, Issue.3
, pp. 566-575
-
-
Chen, R.-W.1
Qin, Z.-H.2
Ren, M.3
Kanai, H.4
Chalecka-Franaszek, E.5
Leeds, P.6
Chuang, D.-M.7
-
57
-
-
0032478088
-
Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx
-
DOI 10.1073/pnas.95.5.2642
-
Nonaka S, Hough CJ, Chuang DM. Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx. Proc Natl Acad Sci U S A 1998; 95: 2642-7. (Pubitemid 28145996)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.5
, pp. 2642-2647
-
-
Nonaka, S.1
Hough, C.J.2
Chuang, D.-M.3
-
58
-
-
0030757168
-
Transient ischemia differentially increases tyrosine phosphorylation of NMDA receptor subunits 2A and 2B
-
Takagi N, Shinno K, Teves L, Bissoon N, Wallace MC, Gurd JW. Transient ischemia differentially increases tyrosine phosphorylation of NMDA receptor subunits 2A and 2B. J Neurochem 1997; 69: 1060-5. (Pubitemid 27364826)
-
(1997)
Journal of Neurochemistry
, vol.69
, Issue.3
, pp. 1060-1065
-
-
Takagi, N.1
Shinno, K.2
Teves, L.3
Bissoon, N.4
Wallace, M.C.5
Gurd, J.W.6
-
59
-
-
0036328597
-
Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: Involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine phosphorylation
-
DOI 10.1046/j.0022-3042.2001.00728.x
-
Hashimoto R, Hough C, Nakazawa T, Yamamoto T, Chuang DM. Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine phosphorylation. J Neurochem 2002; 80: 589-97. (Pubitemid 34809967)
-
(2002)
Journal of Neurochemistry
, vol.80
, Issue.4
, pp. 589-597
-
-
Hashimoto, R.1
Hough, C.2
Nakazawa, T.3
Yamamoto, T.4
Chuang, D.-M.5
-
60
-
-
0042574206
-
Lithium reduced N-methyl-D-aspartate receptor subunit 2A tyrosine phosphorylation and its interactions with Src and Fyn mediated by PSD-95 in rat hippocampus following cerebral ischemia
-
DOI 10.1016/S0304-3940(03)00784-5
-
Ma J, Zhang GY. Lithium reduced N-methyl-D-aspartate receptor subunit 2A tyrosine phosphorylation and its interactions with Src and Fyn mediated by PSD-95 in rat hippocampus following cerebral ischemia. Neurosci Lett 2003; 348: 185-9. (Pubitemid 36980663)
-
(2003)
Neuroscience Letters
, vol.348
, Issue.3
, pp. 185-189
-
-
Ma, J.1
Zhang, G.-Y.2
-
62
-
-
0036914074
-
Lithium induces brain-derived neurotrophic factor and activates TrkB in rodent cortical neurons: An essential step for neuroprotection against glutamate excitotoxicity
-
DOI 10.1016/S0028-3908(02)00217-4
-
Hashimoto R, Takei N, Shimazu K, Christ L, Lu B, Chuang DM. Lithium induces brain-derived neurotrophic factor and activates TrkB in rodent cortical neurons: an essential step for neuroprotection against glutamate excitotoxicity. Neuropharmacology 2002; 43: 1173-9. (Pubitemid 36009371)
-
(2002)
Neuropharmacology
, vol.43
, Issue.7
, pp. 1173-1179
-
-
Hashimoto, R.1
Takei, N.2
Shimazu, K.3
Christ, L.4
Lu, B.5
Chuang, D.-M.6
-
63
-
-
0030702123
-
Akt phosphorylation of BAD couples survival signals to the cell- intrinsic death machinery
-
DOI 10.1016/S0092-8674(00)80405-5
-
Datta SR, Dudek H, Tao X, Masters S, Fu H, Gotoh Y, et al. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 1997; 91: 231-41. (Pubitemid 27456390)
-
(1997)
Cell
, vol.91
, Issue.2
, pp. 231-241
-
-
Datta, S.R.1
Dudek, H.2
Xu, T.3
Masters, S.4
Haian, F.5
Gotoh, Y.6
Greenberg, M.E.7
-
64
-
-
0030710188
-
Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway
-
DOI 10.1093/emboj/16.20.6151
-
Skorski T, Bellacosa A, Nieborowska-Skorska M, Majewski M, Martinez R, Choi JK, et al. Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3K/Akt-dependent pathway. EMB J 1997; 16: 6151-61. (Pubitemid 27458335)
-
(1997)
EMBO Journal
, vol.16
, Issue.20
, pp. 6151-6161
-
-
Skorski, T.1
Bellacosa, A.2
Nieborowska-Skorska, M.3
Majewski, M.4
Martinez, R.5
Choi, J.K.6
Trotta, R.7
Wlodarski, P.8
Perrotti, D.9
Chan, T.O.10
Wasik, M.A.11
Tsichlis, P.N.12
Calabretta, B.13
-
65
-
-
0033525538
-
Long term lithium treatment suppresses p53 and bax expression but increases bcl-2 expression a prominent role in neuroprotection against excitotoxicity
-
Chen RW, Chuang DM. Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity. J Biol Chem 1999; 274: 6039-42.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 6039-6042
-
-
Chen, R.W.1
Chuang, D.M.2
-
67
-
-
0033970158
-
JNK and p38 stresskinases - Degenerative effectors of signal- transduction-cascades in the nervous system
-
DOI 10.1016/S0301-0082(99)00042-8, PII S0301008299000428
-
Mielke K, Herdegen T. JNK and p38 stresskinases-degenerative effectors of signal-transduction-cascades in the nervous system. Prog Neurobiol 2000; 61: 45-60. (Pubitemid 30100402)
-
(2000)
Progress in Neurobiology
, vol.61
, Issue.1
, pp. 45-60
-
-
Mielke, K.1
Herdegen, T.2
-
68
-
-
0029808748
-
Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways
-
DOI 10.1007/s001090050063
-
Whitmarsh AJ, Davis RJ. Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways. J Mol Med 1996; 74: 589-607. (Pubitemid 26343761)
-
(1996)
Journal of Molecular Medicine
, vol.74
, Issue.10
, pp. 589-607
-
-
Whitmarsh, A.J.1
Davis, R.J.2
-
69
-
-
0037967151
-
Chronic treatment with a low dose of lithium protects the brain against ischemic injury by reducing apoptotic death
-
DOI 10.1161/01.STR.0000066308.25088.64
-
Xu J, Culman J, Blume A, Brecht S, Gohlke P. Chronic treatment with a low dose of lithium protects the brain against ischemic injury by reducing apoptotic death. Stroke 2003; 34: 1287-92. (Pubitemid 36547530)
-
(2003)
Stroke
, vol.34
, Issue.5
, pp. 1287-1292
-
-
Xu, J.1
Culman, J.2
Blume, A.3
Brecht, S.4
Gohlke, P.5
-
70
-
-
70350752515
-
Calpains as a target for therapy of neurodegenerative diseases: Putative role of lithium
-
Camins A, Crespo-Biel N, Junyent F, Verdaguer E, Canudas AM, Pallas M. Calpains as a target for therapy of neurodegenerative diseases: putative role of lithium. Curr Drug Metab 2009; 10: 433-47.
-
(2009)
Curr. Drug. Metab.
, vol.10
, pp. 433-447
-
-
Camins, A.1
Crespo-Biel, N.2
Junyent, F.3
Verdaguer, E.4
Canudas, A.M.5
Pallas, M.6
-
71
-
-
79958730602
-
Lithium reduces apoptosis and autophagy after neonatal hypoxiaischemia
-
Li Q, Li H, Roughton K, Wang X, Kroemer G, Blomgren K, et al. Lithium reduces apoptosis and autophagy after neonatal hypoxiaischemia. Cell Death Dis 2010; 1: e56.
-
(2010)
Cell Death Dis.
, vol.1
-
-
Li, Q.1
Li, H.2
Roughton, K.3
Wang, X.4
Kroemer, G.5
Blomgren, K.6
-
72
-
-
0033773645
-
Opposing actions of phosphatidylinositol 3-kinase and glycogen synthase kinase-3beta in the regulation of HSF-1 activity
-
Bijur GN, Jope RS. Opposing actions of phosphatidylinositol 3-kinase and glycogen synthase kinase-3beta in the regulation of HSF-1 activity. J Neurochem 2000; 75: 2401-8.
-
(2000)
J. Neurochem.
, vol.75
, pp. 2401-2418
-
-
Bijur, G.N.1
Jope, R.S.2
-
73
-
-
0034537290
-
Autophagy as a regulated pathway of cellular degradation
-
DOI 10.1126/science.290.5497.1717
-
Klionsky DJ, Emr SD. Autophagy as a regulated pathway of cellular degradation. Science 2000; 290: 1717-21. (Pubitemid 32004796)
-
(2000)
Science
, vol.290
, Issue.5497
, pp. 1717-1721
-
-
Klionsky, D.J.1
Emr, S.D.2
-
74
-
-
50249189191
-
Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways
-
Wen YD, Sheng R, Zhang LS, Han R, Zhang X, Zhang XD, et al. Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways. Autophagy 2008; 4: 762-9.
-
(2008)
Autophagy
, vol.4
, pp. 762-769
-
-
Wen, Y.D.1
Sheng, R.2
Zhang, L.S.3
Han, R.4
Zhang, X.5
Zhang, X.D.6
-
75
-
-
25444483066
-
Lithium induces autophagy by inhibiting inositol monophosphatase
-
DOI 10.1083/jcb.200504035
-
Sarkar S, Floto RA, Berger Z, Imarisio S, Cordenier A, Pasco M, et al. Lithium induces autophagy by inhibiting inositol monophosphatase. J Cell Biol 2005; 170: 1101-11. (Pubitemid 41362642)
-
(2005)
Journal of Cell Biology
, vol.170
, Issue.7
, pp. 1101-1111
-
-
Sarkar, S.1
Floto, R.A.2
Berger, Z.3
Imarisio, S.4
Cordenier, A.5
Pasco, M.6
Cook, L.J.7
Rubinsztein, D.C.8
-
76
-
-
26444515364
-
Autophagy and its possible roles in nervous system diseases damage and repair
-
Rubinsztein DC, DiFiglia M, Heintz N, Nixon RA, Qin ZH, Ravikumar B, et al. Autophagy and its possible roles in nervous system diseases, damage and repair. Autophagy 2005; 1: 11-22.
-
(2005)
Autophagy
, vol.1
, pp. 11-22
-
-
Rubinsztein, D.C.1
DiFiglia, M.2
Heintz, N.3
Nixon, R.A.4
Qin, Z.H.5
Ravikumar, B.6
-
77
-
-
80053570706
-
Lithium-mediated long-term neuroprotection in neonatal rat hypoxia-ischemia is associated with antiinflammatory effects and enhanced proliferation and survival of neural stem/progenitor cells
-
Li H, Li Q, Du X, Sun Y, Wang X, Kroemer G, et al. Lithium-mediated long-term neuroprotection in neonatal rat hypoxia-ischemia is associated with antiinflammatory effects and enhanced proliferation and survival of neural stem/progenitor cells. J Cereb Blood Flow Metab 2011; 31: 2106-15.
-
(2011)
J. Cereb. Blood Flow. Metab.
, vol.31
, pp. 2106-2115
-
-
Li, H.1
Li, Q.2
Du, X.3
Sun, Y.4
Wang, X.5
Kroemer, G.6
-
78
-
-
63549151154
-
Lipopolysaccharide-induced interleukin-6 production is controlled by glycogen synthase kinase-3 and STAT3 in the brain
-
Beurel E, Jope RS. Lipopolysaccharide-induced interleukin-6 production is controlled by glycogen synthase kinase-3 and STAT3 in the brain. J Neuroinflammation 2009; 6: 9.
-
(2009)
J. Neuroinflammation.
, vol.6
, pp. 9
-
-
Beurel, E.1
Jope, R.S.2
-
79
-
-
39349098830
-
Functional MRI of delayed chronic lithium treatment in rat focal cerebral ischemia
-
DOI 10.1161/STROKEAHA.107.492215, PII 0000767020080200000039
-
Kim YR, van Meer MP, Tejima E, Murata Y, Mandeville JB, Dai G, et al. Functional MRI of delayed chronic lithium treatment in rat focal cerebral ischemia. Stroke 2008; 39: 439-47. (Pubitemid 351619469)
-
(2008)
Stroke
, vol.39
, Issue.2
, pp. 439-447
-
-
Kim, Y.R.1
Van Meer, M.P.A.2
Tejima, E.3
Murata, Y.4
Mandeville, J.B.5
Dai, G.6
Chuang, D.-M.7
Rosen, B.R.8
Lo, E.H.9
-
80
-
-
60549098224
-
Lithium upregulates vascular endothelial growth factor in brain endothelial cells and astrocytes
-
Guo S, Arai K, Stins MF, Chuang DM, Lo EH. Lithium upregulates vascular endothelial growth factor in brain endothelial cells and astrocytes. Stroke 2009; 40: 652-5.
-
(2009)
Stroke
, vol.40
, pp. 652-655
-
-
Guo, S.1
Arai, K.2
Stins, M.F.3
Chuang, D.M.4
Lo, E.H.5
-
81
-
-
78650952468
-
Effects of mood stabilizers on adult dentate gyrus-derived neural precursor cells
-
Boku S, Nakagawa S, Masuda T, Nishikawa H, Kato A, Toda H, et al. Effects of mood stabilizers on adult dentate gyrus-derived neural precursor cells. Prog Neuropsychopharmacol Biol Psychiatry 2011; 35: 111-7.
-
(2011)
Prog. Neuropsychopharmacol. Biol. Psychiatry.
, vol.35
, pp. 111-117
-
-
Boku, S.1
Nakagawa, S.2
Masuda, T.3
Nishikawa, H.4
Kato, A.5
Toda, H.6
-
82
-
-
1842419074
-
Lithium selectively increases neuronal differentiation of hippocampal neural progenitor cells both in vitro and in vivo
-
DOI 10.1046/j.1471-4159.2004.02329.x
-
Kim JS, Chang MY, Yu IT, Kim JH, Lee SH, Lee YS, et al. Lithium selectively increases neuronal differentiation of hippocampal neural progenitor cells both in vitro and in vivo. J Neurochem 2004; 89: 324-36. (Pubitemid 38495981)
-
(2004)
Journal of Neurochemistry
, vol.89
, Issue.2
, pp. 324-336
-
-
Kim, J.S.1
Chang, M.-Y.2
Yu, I.T.3
Kim, J.H.4
Lee, S.-H.5
Lee, Y.-S.6
Son, H.7
-
83
-
-
0033817849
-
Enhancement of hippocampal neurogenesis by lithium
-
Chen G, Rajkowska G, Du F, Seraji-Bozorgzad N, Manji HK. Enhancement of hippocampal neurogenesis by lithium. J Neurochem 2000; 75: 1729-34.
-
(2000)
J. Neurochem.
, vol.75
, pp. 1729-1734
-
-
Chen, G.1
Rajkowska, G.2
Du, F.3
Seraji-Bozorgzad, N.4
Manji, H.K.5
-
84
-
-
34548009382
-
Lithium regulates hippocampal neurogenesis by ERK pathway and facilitates recovery of spatial learning and memory in rats after transient global cerebral ischemia
-
DOI 10.1016/j.neuropharm.2007.06.020, PII S0028390807001815
-
Yan XB, Hou HL, Wu LM, Liu J, Zhou JN. Lithium regulates hippocampal neurogenesis by ERK pathway and facilitates recovery of spatial learning and memory in rats after transient global cerebral ischemia. Neuropharmacology 2007; 53: 487-95. (Pubitemid 47284182)
-
(2007)
Neuropharmacology
, vol.53
, Issue.4
, pp. 487-495
-
-
Yan, X.-B.1
Hou, H.-L.2
Wu, L.-M.3
Liu, J.4
Zhou, J.-N.5
-
85
-
-
67650079547
-
Role of Ak and ERK signaling in the neurogenesis following brain ischemia
-
Shioda N, Han F, Fukunaga K. Role of Akt and ERK signaling in the neurogenesis following brain ischemia. Int Rev Neurobiol 2009; 85: 375-87.
-
(2009)
Int. Rev. Neurobiol.
, vol.85
, pp. 375-387
-
-
Shioda, N.1
Han, F.2
Fukunaga, K.3
-
86
-
-
0025968032
-
Lithium ion does not protect brain against transient ischemia in gerbils
-
Yoshida S, Kirino T, Tamura A, Basugi N, Sano K. Lithium ion does not protect brain against transient ischemia in gerbils. Stroke 1991; 22: 84-9.
-
(1991)
Stroke
, vol.22
, pp. 84-89
-
-
Yoshida, S.1
Kirino, T.2
Tamura, A.3
Basugi, N.4
Sano, K.5
-
87
-
-
3042651448
-
Valproic acid reduces brain damage induced by transient focal cerebral ischemia in rats: Potential roles of histone deacetylase inhibition and heat shock protein induction
-
DOI 10.1111/j.1471-4159.2004.02406.x
-
Ren M, Leng Y, Jeong M, Leeds PR, Chuang DM. Valproic acid reduces brain damage induced by transient focal cerebral ischemia in rats: potential roles of histone deacetylase inhibition and heat shock protein induction. J Neurochem 2004; 89: 1358-67. (Pubitemid 38802657)
-
(2004)
Journal of Neurochemistry
, vol.89
, Issue.6
, pp. 1358-1367
-
-
Ren, M.1
Leng, Y.2
Jeong, M.3
Leeds, P.R.4
Chuang, D.-M.5
-
88
-
-
34248530339
-
Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: Multiple mechanisms of action
-
DOI 10.1124/jpet.107.120188
-
Kim HJ, Rowe M, Ren M, Hong JS, Chen PS, Chuang DM. Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: multiple mechanisms of action. J Pharmacol Exp Ther 2007; 321: 892-901. (Pubitemid 46762687)
-
(2007)
Journal of Pharmacology and Experimental Therapeutics
, vol.321
, Issue.3
, pp. 892-901
-
-
Hyeon, J.K.1
Rowe, M.2
Ren, M.3
Hong, J.-S.4
Chen, P.-S.5
Chuang, D.-M.6
-
89
-
-
79251492696
-
Neuroprotection by valproic Acid in mouse models of permanent and transient focal cerebral ischemia
-
Qian YR, Lee MJ, Hwang S, Kook JH, Kim JK, Bae CS. Neuroprotection by valproic Acid in mouse models of permanent and transient focal cerebral ischemia. Korean J Physiol Pharmacol 2010; 14: 435-40.
-
(2010)
Korean J. Physiol. Pharmacol.
, vol.14
, pp. 435-440
-
-
Qian, Y.R.1
Lee, M.J.2
Hwang, S.3
Kook, J.H.4
Kim, J.K.5
Bae, C.S.6
-
90
-
-
18244383806
-
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells
-
DOI 10.1093/emboj/20.24.6969
-
Gottlicher M, Minucci S, Zhu P, Kramer OH, Schimpf A, Giavara S, et al. Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells. EMBO J 2001; 20: 6969-78. (Pubitemid 34062289)
-
(2001)
EMBO Journal
, vol.20
, Issue.24
, pp. 6969-6978
-
-
Gottlicher, M.1
Minucci, S.2
Zhu, P.3
Kramer, O.H.4
Schimpf, A.5
Giavara, S.6
Sleeman, J.P.7
Lo Coco, F.8
Nervi, C.9
Pelicci, P.G.10
Heinzel, T.11
-
91
-
-
0035965343
-
Histone deacetylase is a direct target of valproic acid a potent anticonvulsant mood stabilizer and teratogen
-
Phiel CJ, Zhang F, Huang EY, Guenther MG, Lazar MA, Klein PS. Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. J Biol Chem 2001; 276: 36734-41.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 36734-36741
-
-
Phiel, C.J.1
Zhang, F.2
Huang, E.Y.3
Guenther, M.G.4
Lazar, M.A.5
Klein, P.S.6
-
92
-
-
33746065340
-
Endogenous α-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity
-
DOI 10.1523/JNEUROSCI.0096-06.2006
-
Leng Y, Chuang DM. Endogenous alpha-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity. J Neurosci 2006; 26: 7502-12. (Pubitemid 44315219)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.28
, pp. 7502-7512
-
-
Leng, Y.1
Chuang, D.-M.2
-
93
-
-
5044240976
-
Valproic acid inhibits histone deacetylase activity and suppresses excitotoxicity-induced GAPDH nuclear accumulation and apoptotic death in neurons
-
DOI 10.1038/sj.tpj.6500269
-
Kanai H, Sawa A, Chen RW, Leeds P, Chuang DM. Valproic acid inhibits histone deacetylase activity and suppresses excitotoxicityinduced GAPDH nuclear accumulation and apoptotic deh in neurons. Pharmacogenomics J 2004; 4: 336-44. (Pubitemid 39341573)
-
(2004)
Pharmacogenomics Journal
, vol.4
, Issue.5
, pp. 336-344
-
-
Kanai, H.1
Sawa, A.2
Chen, R.-W.3
Leeds, P.4
Chuang, D.-M.5
-
94
-
-
29044447411
-
Chronic treatment with mood stabilizers lithium and valproate prevents excitotoxicity by inhibiting oxidative stress in rat cerebral cortical cells
-
DOI 10.1016/j.biopsych.2005.04.052, PII S000632230500572X
-
Shao L, Young LT, Wang JF. Chronic treatment with mood stabilizers lithium and valproate prevents excitotoxicity by inhibiting oxidative stress in rat cerebral cortical cells. Biol Psychiatry 2005; 58: 879-84. (Pubitemid 41790716)
-
(2005)
Biological Psychiatry
, vol.58
, Issue.11
, pp. 879-884
-
-
Shao, L.1
Young, L.T.2
Wang, J.-F.3
-
95
-
-
40449135649
-
Synergistic neuroprotective effects of lithium and valproic acid or other histone deacetylase inhibitors in neurons: Roles of glycogen synthase kinase-3 inhibition
-
DOI 10.1523/JNEUROSCI.5467-07.2008
-
Leng Y, Liang MH, Ren M, Marinova Z, Leeds P, Chuang DM. Synergistic neuroprotective effects of lithium and valproic acid or other histone deacetylase inhibitors in neurons: roles of glycogen synthase kinase-3 inhibition. J Neurosci 2008; 28: 2576-88. (Pubitemid 351348211)
-
(2008)
Journal of Neuroscience
, vol.28
, Issue.10
, pp. 2576-2588
-
-
Leng, Y.1
Liang, M.-H.2
Ren, M.3
Marinova, Z.4
Leeds, P.5
Chuang, D.-M.6
-
96
-
-
34147199586
-
Valproic acid-mediated neuroprotection in intracerebral hemorrhage via histone deacetylase inhibition and transcriptional activation
-
DOI 10.1016/j.nbd.2007.02.006, PII S0969996107000423
-
Sinn DI, Kim SJ, Chu K, Jung KH, Lee ST, Song EC, et al. Valproic acid-mediated neuroprotection in intracerebral hemorrhage via histone deacetylase inhibition and transcriptional activation. Neurobiol Dis 2007; 26: 464-72. (Pubitemid 46578295)
-
(2007)
Neurobiology of Disease
, vol.26
, Issue.2
, pp. 464-472
-
-
Sinn, D.-I.1
Kim, S.-J.2
Chu, K.3
Jung, K.-H.4
Lee, S.-T.5
Song, E.-C.6
Kim, J.-M.7
Park, D.-K.8
Kun Lee, S.9
Kim, M.10
Roh, J.-K.11
-
97
-
-
15544387446
-
Valproate pretreatment protects dopaminergic neurons from LPS-induced neurotoxicity in rat primary midbrain cultures: Role of microglia
-
DOI 10.1016/j.molbrainres.2004.10.021
-
Peng GS, Li G, Tzeng NS, Chen PS, Chuang DM, Hsu YD, et al. Valproate pretreatment protects dopaminergic neurons from LPSinduced neurotoxicity in rat primary midbrain cultures: role of microgia. Brain Res Mol Brain Res 2005; 134: 162-9. (Pubitemid 40403648)
-
(2005)
Molecular Brain Research
, vol.134
, Issue.1
, pp. 162-169
-
-
Peng, G.-S.1
Li, G.2
Tzeng, N.-S.3
Chen, P.-S.4
Chuang, D.-M.5
Hsu, Y.-D.6
Yang, S.7
Hong, J.-S.8
-
98
-
-
33845296450
-
Valproate protects dopaminergic neurons in midbrain neuron/glia cultures by stimulating the release of neurotrophic factors from astrocytes
-
DOI 10.1038/sj.mp.4001893, PII 4001893
-
Chen PS, Peng GS, Li G, Yang S, Wu X, Wang CC, et al. Valproate protects dopaminergic neurons in midbrain neuron/glia cultures by stimulating the release of neurotrophic factors from astrocytes. Mol Psychiatry 2006; 11: 1116-25. (Pubitemid 44867481)
-
(2006)
Molecular Psychiatry
, vol.11
, Issue.12
, pp. 1116-1125
-
-
Chen, P.-S.1
Peng, G.-S.2
Li, G.3
Yang, S.4
Wu, X.5
Wang, C.-C.6
Wilson, B.7
Lu, R.-B.8
Gean, P.-W.9
Chuang, D.-M.10
Hong, J.-S.11
-
99
-
-
33751120697
-
Pharmacological inhibition of histone deacetylases by suberoylanilide hydroxamic acid specifically alters gene expression and reduces ischemic injury in the mouse brain
-
DOI 10.1124/mol.106.027912
-
Faraco G, Pancani T, Formentini L, Mascagni P, Fossati G, Leoni F, et al. Pharmacological inhibition of histone deacetylases by suberoylanilide hydroxamic acid specifically alters gene expression and reduces ischemic injury in the mouse brain. Mol Pharmacol 2006; 70: 1876-84. (Pubitemid 44771903)
-
(2006)
Molecular Pharmacology
, vol.70
, Issue.6
, pp. 1876-1884
-
-
Faraco, G.1
Pancani, T.2
Formentini, L.3
Mascagni, P.4
Fossati, G.5
Leoni, F.6
Moroni, F.7
Chiarugi, A.8
-
100
-
-
70350133780
-
Valproic acid induces functional heat-shock protein 70 via class I histone deacetylase inhibition in cortical neurons: A potential role of Sp1 acetylation
-
Marinova Z, Ren M, Wendland JR, Leng Y, Liang MH, Yasuda S, et al. Valproic acid induces functional heat-shock protein 70 via class I histone deacetylase inhibition in cortical neurons: a potential role of Sp1 acetylation. J Neurochem 2009; 111: 976-87.
-
(2009)
J. Neurochem.
, vol.111
, pp. 976-987
-
-
Marinova, Z.1
Ren, M.2
Wendland, J.R.3
Leng, Y.4
Liang, M.H.5
Yasuda, S.6
-
101
-
-
79954577753
-
Histone deacetylase inhibition alters histone methylation associated with heat shock protein 70 promoter modifications in astrocytes and neurons
-
Marinova Z, Leng Y, Leeds P, Chuang DM. Histone deacetylase inhibition alters histone methylation associated with heat shock protein 70 promoter modifications in astrocytes and neurons. Neuropharmacology 2011; 60: 1109-15.
-
(2011)
Neuropharmacology
, vol.60
, pp. 1109-1115
-
-
Marinova, Z.1
Leng, Y.2
Leeds, P.3
Chuang, D.M.4
-
102
-
-
37549004821
-
Anti-inflammatory effects of the 70 kDa heat shock protein in experimental stroke
-
Zheng Z, Kim JY, Ma H, Lee JE, Yenari MA. Anti-inflammatory effects of the 70 kDa heat shock protein in experimental stroke. J Cereb Blood Flow Metab 2008; 28: 53-63.
-
(2008)
J. Cereb. Blood Flow. Metab.
, vol.28
, pp. 53-63
-
-
Zheng, Z.1
Kim, J.Y.2
Ma, H.3
Lee, J.E.4
Yenari, M.A.5
-
103
-
-
78650919356
-
Valproic acid attenuates blood-brain barrier disruption in a rat model of transient focal cerebral ischemia: The roles of HDAC and MMP-9 inhibition
-
Wang Z, Leng Y, Tsai LK, Leeds P, Chuang DM. Valproic acid attenuates blood-brain barrier disruption in a rat model of transient focal cerebral ischemia: the roles of HDAC and MMP-9 inhibition. J Cereb Blood Flow Metab 2011; 31: 52-7.
-
(2011)
J. Cereb. Blood Flow. Metab.
, vol.31
, pp. 52-57
-
-
Wang, Z.1
Leng, Y.2
Tsai, L.K.3
Leeds, P.4
Chuang, D.M.5
-
104
-
-
3242788185
-
Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis
-
DOI 10.1523/JNEUROSCI.5747-03.2004
-
Hao Y, Creson T, Zhang L, Li P, Du F, Yuan P, et al. Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis. J Neurosci 2004; 24: 6590-9. (Pubitemid 38971708)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.29
, pp. 6590-6599
-
-
Hao, Y.1
Creson, T.2
Zhang, L.3
Li, P.4
Du, F.5
Yuan, P.6
Gould, T.D.7
Manji, H.K.8
Chen, G.9
-
105
-
-
9344252804
-
Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells
-
DOI 10.1073/pnas.0407643101
-
Hsieh J, Nakashima K, Kuwabara T, Mejia E, Gage FH. Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells. Proc Natl Acad Sci U S A 2004; 101: 16659-64. (Pubitemid 39557769)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.47
, pp. 16659-16664
-
-
Hsieh, J.1
Nakashima, K.2
Kuwabara, T.3
Mejia, E.4
Gage, F.H.5
-
106
-
-
67651146826
-
The HDAC inhibitor sodium butyrate stimulates neurogenesis in the ischemic brain
-
Kim HJ, Leeds P, Chuang DM. The HDAC inhibitor, sodium butyrate, stimulates neurogenesis in the ischemic brain. J Neurochem 2009; 110: 1226-40.
-
(2009)
J. Neurochem.
, vol.110
, pp. 1226-1240
-
-
Kim, H.J.1
Leeds, P.2
Chuang, D.M.3
-
107
-
-
58049196879
-
The mood stabilizers lithium and valproate selectively activate the promoter IV of brain-derived neurotrophic factor in neurons
-
Yasuda S, Liang MH, Marinova Z, Yahyavi A, Chuang DM. The mood stabilizers lithium and valproate selectively activate the promoter IV of brain-derived neurotrophic factor in neurons. Mol Psychiatry 2009; 14: 51-9.
-
(2009)
Mol. Psychiatry
, vol.14
, pp. 51-59
-
-
Yasuda, S.1
Liang, M.H.2
Marinova, Z.3
Yahyavi, A.4
Chuang, D.M.5
-
108
-
-
80755133627
-
Bone marrow stem cell mobilization in stroke: Abonehead may be good after all
-
10.1038/ leu. 2011 167
-
Borlongan CV. Bone marrow stem cell mobilization in stroke: a 'bonehead' may be good after all! Leukemia 2011. doi: 10.1038/ leu.2011.167
-
(2011)
Leukemia
-
-
Borlongan, C.V.1
-
109
-
-
78651280399
-
The mood stabilizers valproic acid and lithium enhance mesenchymal stem cell migration via distinct mechanisms
-
Tsai LK, Leng Y, Wang Z, Leeds P, Chuang DM. The mood stabilizers valproic acid and lithium enhance mesenchymal stem cell migration via distinct mechanisms. Neuropsychopharmacology 2010; 35: 2225-37.
-
(2010)
Neuropsychopharmacology
, vol.35
, pp. 2225-2237
-
-
Tsai, L.K.1
Leng, Y.2
Wang, Z.3
Leeds, P.4
Chuang, D.M.5
-
110
-
-
80053309997
-
Mesenchymal stem cells primed with valproate and lithium robustly migrate to infarcted regions and facilitate recovery in a stroke model
-
Tsai LK, Wang Z, Munasinghe J, Leng Y, Leeds P, Chuang DM. Mesenchymal stem cells primed with valproate and lithium robustly migrate to infarcted regions and facilitate recovery in a stroke model. Stroke 2011; 42: 2932-9.
-
(2011)
Stroke
, vol.42
, pp. 2932-2939
-
-
Tsai, L.K.1
Wang, Z.2
Munasinghe, J.3
Leng, Y.4
Leeds, P.5
Chuang, D.M.6
-
111
-
-
0028959228
-
Cerebroprotective effect of lamotrigine after focal ischemia in rats
-
117-21; discussion
-
Smith SE, Meldrum BS. Cerebroprotective effect of lamotrigine after focal ischemia in rats. Stroke 1995; 26: 117-21; discussion 21-2.
-
(1995)
Stroke
, vol.26
, pp. 21-2
-
-
Smith, S.E.1
Meldrum, B.S.2
-
112
-
-
0028800114
-
Neuroprotective effects of lamotrigine in global ischemia in gerbils A histological in vivo microdialysis and behavioral study
-
Shuaib A, Mahmood RH, Wishart T, Kanthan R, Murabit MA, Ijaz S, et al. Neuroprotective effects of lamotrigine in global ischemia in gerbils. A histological, in vivo microdialysis and behavioral study. Brain Res 1995; 702: 199-206.
-
(1995)
Brain Res.
, vol.702
, pp. 199-206
-
-
Shuaib, A.1
Mahmood, R.H.2
Wishart, T.3
Kanthan, R.4
Murabit, M.A.5
Ijaz, S.6
-
113
-
-
0028939058
-
Neuroprotective properties of the novel antiepileptic lamotrigine in a gerbil model of global cerebral ischemia
-
Wiard RP, Dickerson MC, Beek O, Norton R, Cooper BR. Neuroprotective properties of the novel antiepileptic lamotrigine in a gerbil model of global cerebral ischemia. Stroke 1995; 26: 466-72.
-
(1995)
Stroke
, vol.26
, pp. 466-472
-
-
Wiard, R.P.1
Dickerson, M.C.2
Beek, O.3
Norton, R.4
Cooper, B.R.5
-
114
-
-
51349125815
-
Lamotrigine attenuates cerebral vasospasm after experimental subarachnoid hemorrhage in rabbits
-
discussion 51.
-
Seckin H, Yigitkanli K, Besalti O, Kosemehmetoglu K, Ozturk E, Simsek S, et al. Lamotrigine attenuates cerebral vasospasm after experimental subarachnoid hemorrhage in rabbits. Surg Neurol 2008; 70: 344-51; discussion 51.
-
(2008)
Surg. Neurol.
, vol.70
, pp. 344-351
-
-
Seckin, H.1
Yigitkanli, K.2
Besalti, O.3
Kosemehmetoglu, K.4
Ozturk, E.5
Simsek, S.6
-
115
-
-
0022900644
-
Pharmacological studies on lamotrigine a novel potential antiepileptic drug: II neurochemical studies on the mechanism of action
-
Leach MJ, Marden CM, Miller AA. Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action. Epilepsia 1986; 27: 490-7.
-
(1986)
Epilepsia
, vol.27
, pp. 49-47
-
-
Leach, M.J.1
Marden, C.M.2
Miller, A.A.3
-
116
-
-
0030787547
-
+ channels in rat hippocampal neurones
-
DOI 10.1038/sj.bjp.0701221
-
Kuo CC, Lu L. Characterization of lamotrigine inhibition of Na+ channels in rat hippocampal neurones. Br J Pharmacol 1997; 121: 1231-8. (Pubitemid 27303595)
-
(1997)
British Journal of Pharmacology
, vol.121
, Issue.6
, pp. 1231-1238
-
-
Kuo, C.-C.1
Lu, L.2
-
117
-
-
0031056868
-
Lamotrigine inhibits extracellular glutamate accumulation during transient global cerebral ischemia in rabbits
-
DOI 10.1097/00000542-199702000-00021
-
Bacher A, Zornow MH. Lamotrigine inhibits extracellular glutamate accumulation during transient global cerebral ischemia in rabbits. Anesthesiology 1997; 86: 459-63. (Pubitemid 27093390)
-
(1997)
Anesthesiology
, vol.86
, Issue.2
, pp. 459-463
-
-
Bacher, A.1
Zornow, M.H.2
-
118
-
-
0020051129
-
Delayed neuronal death in the gerbil hippocampus following ischemia
-
DOI 10.1016/0006-8993(82)90833-2
-
Kirino T. Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res 1982; 239: 57-69. (Pubitemid 12101768)
-
(1982)
Brain Research
, vol.239
, Issue.1
, pp. 57-69
-
-
Kirino, T.1
-
119
-
-
47349097047
-
Transient cerebral ischemia increases CA1 pyramidal neuron excitability
-
Fan Y, Deng P, Wang YC, Lu HC, Xu ZC, Schulz PE. Transient cerebral ischemia increases CA1 pyramidal neuron excitability. Exp Neurol 2008; 212: 415-21.
-
(2008)
Exp. Neurol.
, vol.212
, pp. 415-421
-
-
Fan, Y.1
Deng, P.2
Wang, Y.C.3
Lu, H.C.4
Xu, Z.C.5
Schulz, P.E.6
-
120
-
-
41649091371
-
Neuroprotection by lamotrigine in a rat model of neonatal hypoxic-ischaemic encephalopathy
-
DOI 10.1017/S1461145707008012, PII S1461145707008012
-
Papazisis G, Kallaras K, Kaiki-Astara A, Pourzitaki C, Tzachanis D, Dagklis T, et al. Neuroprotection by lamotrigine in a rat model of neonatal hypoxic-ischaemic encephalopathy. Int J Neuropsychopharmacol 2008; 11: 321-9. (Pubitemid 351482501)
-
(2008)
International Journal of Neuropsychopharmacology
, vol.11
, Issue.3
, pp. 321-329
-
-
Papazisis, G.1
Kallaras, K.2
Kaiki-Astara, A.3
Pourzitaki, C.4
Tzachanis, D.5
Dagklis, T.6
Kouvelas, D.7
-
121
-
-
82955184853
-
Neuroprotection of lamotrigine on hypoxic-ischemic brain damage in neonatal rats: Relations to administration time and doses
-
Yi YH, Guo WC, Sun WW, Su T, Lin H, Chen SQ, et al. Neuroprotection of lamotrigine on hypoxic-ischemic brain damage in neonatal rats: Relations to administration time and doses. Biologics 2008; 2: 339-44.
-
(2008)
Biologics
, vol.2
, pp. 339-344
-
-
Yi, Y.H.1
Guo, W.C.2
Sun, W.W.3
Su, T.4
Lin, H.5
Chen, S.Q.6
-
122
-
-
0036103182
-
Glycogen synthase kinase-3β, mood stabilizers, and neuroprotection
-
DOI 10.1034/j.1399-5618.2002.40201.x
-
Li X, Bijur GN, Jope RS. Glycogen synthase kinase-3beta, mood stabilizers, and neuroprotection. Bipolar Disord 2002; 4: 137-44. (Pubitemid 34411276)
-
(2002)
Bipolar Disorders
, vol.4
, Issue.2
, pp. 137-144
-
-
Li, X.1
Bijur, G.N.2
Jope, R.S.3
-
123
-
-
59849095290
-
Chronic administration of mood stabilizers upregulates BDNF and bcl-2 expression levels in rat frontal cortex3t
-
Chang YC, Rapoport SI, Rao JS. Chronic administration of mood stabilizers upregulates BDNF and bcl-2 expression levels in rat frontal cortex. Neurochem Res 2009; 34: 536-41.
-
(2009)
Neurochem. Res.
, vol.34
, pp. 536-541
-
-
Chang, Y.C.1
Rapoport, S.I.2
Rao, J.S.3
-
124
-
-
79551525746
-
Lamotrigine increases the number of BrdU-labeled cells in the rat hippocampus
-
Kondziella D, Strandberg J, Lindquist C, Asztely F. Lamotrigine increases the number of BrdU-labeled cells in the rat hippocampus. Neuroreport 2011; 22: 97-100.
-
(2011)
Neuroreport
, vol.22
, pp. 97-100
-
-
Kondziella, D.1
Strandberg, J.2
Lindquist, C.3
Asztely, F.4
-
125
-
-
52649101373
-
Treatment with the glycogen synthase kinase-3beta inhibitor TDZD-8 affects transient cerebral ischemia/reperfusion injury in the rat hippocampus
-
Collino M, Thiemermann C, Mastrocola R, Gallicchio M, Benetti E, Miglio G, et al. Treatment with the glycogen synthase kinase-3beta inhibitor, TDZD-8, affects transient cerebral ischemia/reperfusion injury in the rat hippocampus. Shock 2008; 30: 299-307.
-
(2008)
Shock
, vol.30
, pp. 299-307
-
-
Collino, M.1
Thiemermann, C.2
Mastrocola, R.3
Gallicchio, M.4
Benetti, E.5
Miglio, G.6
-
126
-
-
3042749593
-
Glycogen synthase kinase 3β inhibitor Chir025 reduces neuronal death resulting from oxygen-glucose deprivation, glutamate excitotoxicity, and cerebral ischemia
-
DOI 10.1016/j.expneurol.2004.04.004, PII S0014488604001360
-
Kelly S, Zhao H, Hua Sun G, Cheng D, Qiao Y, Luo J, et al. Glycogen synthase kinase 3beta inhibitor Chir025 reduces neuronal death resulting from oxygen-glucose deprivation, glutamate excitotoxicity, and cerebral ischemia. Exp Neurol 2004; 188: 378-86. (Pubitemid 38891598)
-
(2004)
Experimental Neurology
, vol.188
, Issue.2
, pp. 378-386
-
-
Kelly, S.1
Zhao, H.2
Sun, G.H.3
Cheng, D.4
Qiao, Y.5
Luo, J.6
Martin, K.7
Steinberg, G.K.8
Harrison, S.D.9
Yenari, M.A.10
-
127
-
-
44149110850
-
Inhibition of GSK 3 reduces infarct volume and improves neurobehavioral functions
-
Koh SH, Yoo AR, Chang DI, Hwang SJ, Kim SH. Inhibition of GSK 3 reduces infarct volume and improves neurobehavioral functions. Biochem Biophys Res Commun 2008; 371: 894-9.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.371
, pp. 894-899
-
-
Koh, S.H.1
Yoo, A.R.2
Chang, D.I.3
Hwang, S.J.4
Kim, S.H.5
-
128
-
-
79952369773
-
Glycogen synthase kinase-3 inhibition reduces ischemic cerebral damage restores impaired mitochondrial biogenesis and prevents ROS production
-
Valerio A, Bertolotti P, Delbarba A, Perego C, Dossena M, Ragni M, et al. Glycogen synthase kinase-3 inhibition reduces ischemic cerebral damage, restores impaired mitochondrial biogenesis and prevents ROS production. J Neurochem 2011; 116: 1148-59.
-
(2011)
J. Neurochem.
, vol.116
, pp. 1148-1159
-
-
Valerio, A.1
Bertolotti, P.2
Delbarba, A.3
Perego, C.4
Dossena, M.5
Ragni, M.6
-
129
-
-
78650654039
-
Glycogen synthase kinase-3beta inactivation inhibits tumor necrosis factoralpha production in microglia by modulating nuclear factor kappaB and MLK3/JNK signaling cascades
-
Wang MJ, Huang HY, Chen WF, Chang HF, Kuo JS. Glycogen synthase kinase-3beta inactivation inhibits tumor necrosis factoralpha production in microglia by modulating nuclear factor kappaB and MLK3/JNK signaling cascades. J Neuroinflammation 2010; 7: 99.
-
(2010)
J. Neuroinflammation.
, vol.7
, pp. 99
-
-
Wang, M.J.1
Huang, H.Y.2
Chen, W.F.3
Chang, H.F.4
Kuo, J.S.5
-
130
-
-
68249159584
-
Glycogen synthase kinase-3 negatively regulates anti-inflammatory interleukin-10 for lipopolysaccharide-induced iNOS/NO biosynthesis and RANTES production in microglial cells
-
Huang WC, Lin YS, Wang CY, Tsai CC, Tseng HC, Chen CL, et al. Glycogen synthase kinase-3 negatively regulates anti-inflammatory interleukin-10 for lipopolysaccharide-induced iNOS/NO biosynthesis and RANTES production in microglial cells. Immunology 2009; 128: e275-86.
-
(2009)
Immunology
, vol.128
-
-
Huang, W.C.1
Lin, Y.S.2
Wang, C.Y.3
Tsai, C.C.4
Tseng, H.C.5
Chen, C.L.6
-
131
-
-
64949159019
-
Evidence for selective microRNAs and their effectors as common long-term targets for the actions of mood stabilizers
-
Zhou R, Yuan P, Wang Y, Hunsberger JG, Elkahloun A, Wei Y, et al. Evidence for selective microRNAs and their effectors as common long-term targets for the actions of mood stabilizers. Neuropsychopharmacology 2009; 34: 1395-405.
-
(2009)
Neuropsychopharmacology
, vol.34
, pp. 1395-1405
-
-
Zhou, R.1
Yuan, P.2
Wang, Y.3
Hunsberger, J.G.4
Elkahloun, A.5
Wei, Y.6
-
132
-
-
79952807964
-
MicroRNAs in stroke pathogenesis
-
Tan JR, Koo YX, Kaur P, Liu F, Armugam A, Wong PT, et al. microRNAs in stroke pathogenesis. Curr Mol Med 2011; 11: 76-92.
-
(2011)
Curr. Mol. Med.
, vol.11
, pp. 76-92
-
-
Tan, J.R.1
Koo, Y.X.2
Kaur, P.3
Liu, F.4
Armugam, A.5
Wong, P.T.6
-
133
-
-
41249102422
-
MicroRNA expression in the blood and brain of rats subjected to transient focal ischemia by middle cerebral artery occlusion
-
DOI 10.1161/STROKEAHA.107.500736
-
Jeyaseelan K, Lim KY, Armugam A. MicroRNA expression in the blood and brain of rats subjected to transient focal ischemia by middle cerebral artery occlusion. Stroke 2008; 39: 959-66. (Pubitemid 351619577)
-
(2008)
Stroke
, vol.39
, Issue.3
, pp. 959-966
-
-
Jeyaseelan, K.1
Lim, K.Y.2
Armugam, A.3
|