Chronic treatment with a low dose of lithium protects the brain against ischemic injury by reducing apoptotic death

Stroke

Volumn 34, Issue 5, 2003, Pages 1287-1292

  Xu, Jihong ^a   Culman, Juraj ^b   Blume, Annegret ^b   Brecht, Stephan ^b   Gohlke, Peter ^b  

^a UNIVERSITY OF KIEL   (Germany)

^b NONE

Author keywords

Apoptosis; Cerebral ischemia, focal; Lithium; Microglia; Neuroprotection

Indexed keywords

CASPASE 3; LITHIUM CHLORIDE; PROTEIN C FOS; PROTEIN C JUN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN BLOOD FLOW; BRAIN CORTEX; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN PERFUSION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LOW DRUG DOSE; MALE; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE CELL NECROSIS; NEUROPROTECTION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TREATMENT OUTCOME;

ANIMALS; APOPTOSIS; BIOLOGICAL MARKERS; BRAIN EDEMA; BRAIN ISCHEMIA; CASPASE 3; CASPASES; CEREBROVASCULAR CIRCULATION; DEPRESSION, CHEMICAL; DRUG ADMINISTRATION SCHEDULE; DRUG EVALUATION, PRECLINICAL; IN SITU NICK-END LABELING; INFARCTION, MIDDLE CEREBRAL ARTERY; LITHIUM CARBONATE; MALE; MICROGLIA; NERVE TISSUE PROTEINS; NEUROPROTECTIVE AGENTS; RATS; RATS, WISTAR; REPERFUSION INJURY; SINGLE-BLIND METHOD; TRANSCRIPTION FACTOR AP-1;

EID: 0037967151     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.0000066308.25088.64     Document Type: Article

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