Lithium-mediated long-term neuroprotection in neonatal rat hypoxia-ischemia is associated with antiinflammatory effects and enhanced proliferation and survival of neural stem/progenitor cells

Journal of Cerebral Blood Flow and Metabolism

Volumn 31, Issue 10, 2011, Pages 2106-2115

  Li, Hongfu ^a,b   Li, Qian ^a,b   Du, Xiaonan ^a,b   Sun, Yanyan ^a,b   Wang, Xiaoyang ^a,b   Kroemer, Guido ^c,d,e,f,g   Blomgren, Klas ^a,h   Zhu, Changlian ^a,b  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b ZHENGZHOU UNIVERSITY   (China)

^c INSERM   (France)

^d INSTITUT GUSTAVE ROUSSY   (France)

^e CENTRE DE RECHERCHE DES CORDELIERS   (France)

^f HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^g UNIVERSITÉ PARIS DESCARTES   (France)

^h QUEEN SILVIA CHILDREN'S HOSPITAL   (Sweden)

Author keywords

asphyxia; inflammation; microglia; neurogenesis; stem cell

Indexed keywords

BROXURIDINE; GALECTIN 3; HISTONE H3; INTERLEUKIN 1BETA; LITHIUM CHLORIDE; MONOCYTE CHEMOTACTIC PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DRUG EFFECT; HYPOXIC ISCHEMIC ENCEPHALOPATHY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LABELING INDEX; MALE; MICROGLIA; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NEUROPROTECTION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; STEM CELL;

ANIMALS; ANIMALS, NEWBORN; ANTIMANIC AGENTS; ASTROCYTES; BRAIN; CELL PROLIFERATION; CHEMOKINE CCL2; GALECTIN 3; HYPOXIA-ISCHEMIA, BRAIN; INFLAMMATION; INTERLEUKIN-1BETA; LITHIUM CHLORIDE; MALE; NEURAL STEM CELLS; NEURONS; NEUROPROTECTIVE AGENTS; RATS; RATS, WISTAR; TIME FACTORS;

EID: 80053570706     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2011.75     Document Type: Article

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