Activation of hypoxia-inducible factor-1 protects airway epithelium against oxidant-induced barrier dysfunction

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 301, Issue 6, 2011, Pages

  Olson, Nels ^a   Hristova, Milena ^a   Heintz, Nicholas H ^a   Lounsbury, Karen M ^a   van der Vliet, Albert ^a  

^a UNIVERSITY OF VERMONT   (United States)

Author keywords

Hydrogen peroxide; Lung; Occludin; Permeability; Peroxiredoxin; Sestrin 2

Indexed keywords

BETA ACTIN; CATALASE; CLAUDIN 1; DIMETHYLOXALYLGLYCINE; ENZYME INHIBITOR; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; HYDROGEN PEROXIDE; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LIFICIGUAT; OCCLUDIN; PEROXIREDOXIN; PEROXIREDOXIN 1; PEROXIREDOXIN 2; REGULATOR PROTEIN; SESTRIN 2; SHORT HAIRPIN RNA; THIOREDOXIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRONCHUS MUCOSA; CELL DAMAGE; CELL VIABILITY; ELECTRIC RESISTANCE; ENZYME METABOLISM; GENE SEQUENCE; HUMAN; HUMAN CELL; HYPOXIA; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION; RESPIRATORY EPITHELIUM; SIGNAL TRANSDUCTION; TRACHEA MUCOSA;

AMINO ACIDS, DICARBOXYLIC; ANIMALS; CELL HYPOXIA; CELL LINE; COBALT; DEXTRANS; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; GENE KNOCKDOWN TECHNIQUES; HUMANS; HYDROGEN PEROXIDE; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; NUCLEAR PROTEINS; OXIDANTS; OXIDATION-REDUCTION; OXIDATIVE STRESS; PERMEABILITY; PEROXIREDOXINS; PRIMARY CELL CULTURE; PROCOLLAGEN-PROLINE DIOXYGENASE; RESPIRATORY MUCOSA; RNA INTERFERENCE; TRACHEA;

EID: 82855176887     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00250.2011     Document Type: Article

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