-
1
-
-
33747621613
-
Regulation of physiological responses to continuous and intermittent hypoxia by hypoxia-inducible factor 1
-
DOI 10.1113/expphysiol.2006.033498
-
Semenza GL (2006) Regulation of physiological responses to continuous and intermittent hypoxia by hypoxia-inducible factor 1. Exp Physiol 91:803-806. (Pubitemid 44266576)
-
(2006)
Experimental Physiology
, vol.91
, Issue.5
, pp. 803-806
-
-
Semenza, G.L.1
-
2
-
-
0345491599
-
Differential Roles of Hypoxia-Inducible Factor 1alpha (HIF-1alpha) and HIF-2alpha in Hypoxic Gene Regulation
-
DOI 10.1128/MCB.23.24.9361-9374.2003
-
Hu CJ, Wang LY, Chodosh LA, Keith B, Simon MC (2003) Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation. Mol Cell Biol 23:9361-9374. (Pubitemid 37499822)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.24
, pp. 9361-9374
-
-
Hu, C.-J.1
Wang, L.-Y.2
Chodosh, L.A.3
Keith, B.4
Simon, M.C.5
-
3
-
-
2342597973
-
Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth
-
Kondo K, Kim WY, Lechpammer M, Kaelin WG, Jr (2003) Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth. PLoS Biol 1:E83.
-
(2003)
PLoS Biol
, vol.1
-
-
Kondo, K.1
Kim, W.Y.2
Lechpammer, M.3
Kaelin Jr., W.G.4
-
4
-
-
40949088476
-
Biology of hypoxia-inducible factor-2alpha in development and disease
-
Patel SA, Simon MC (2008) Biology of hypoxia-inducible factor-2alpha in development and disease. Cell Death Differ 15:628-634.
-
(2008)
Cell Death Differ
, vol.15
, pp. 628-634
-
-
Patel, S.A.1
Simon, M.C.2
-
6
-
-
33750630119
-
Recruitment of HIF-1alpha and HIF-2alpha to common target genes is differentially regulated in neuroblastoma: HIF-2alpha promotes an aggressive phenotype
-
DOI 10.1016/j.ccr.2006.08.026, PII S153561080600290X
-
Holmquist-Mengelbier L, et al. (2006) Recruitment of HIF-1alpha and HIF-2alpha to common target genes is differentially regulated in neuroblastoma: HIF-2alpha promotes an aggressive phenotype. Cancer Cell 10:413-423. (Pubitemid 44693470)
-
(2006)
Cancer Cell
, vol.10
, Issue.5
, pp. 413-423
-
-
Holmquist-Mengelbier, L.1
Fredlund, E.2
Lofstedt, T.3
Noguera, R.4
Navarro, S.5
Nilsson, H.6
Pietras, A.7
Vallon-Christersson, J.8
Borg, A.9
Gradin, K.10
Poellinger, L.11
Pahlman, S.12
-
7
-
-
12144287073
-
Prognostic significance of endothelial Per-Arnt-Sim domain protein 1/hypoxia-inducible factor-2alpha expression in a subset of tumor associated macrophages in invasive bladder cancer
-
DOI 10.1097/01.ju.0000110541.62972.08
-
Koga F, et al. (2004) Prognostic significance of endothelial Per-Arnt-sim domain protein 1/hypoxia-inducible factor-2alpha expression in a subset of tumor associated macrophages in invasive bladder cancer. J Urol 171:1080-1084. (Pubitemid 38327531)
-
(2004)
Journal of Urology
, vol.171
, Issue.3
, pp. 1080-1084
-
-
Koga, F.1
Kageyama, Y.2
Kawakami, S.3
Fujii, Y.4
Hyochi, N.5
Ando, N.6
Takizawa, T.7
Saito, K.8
Iwai, A.9
Masuda, H.10
Kihara, K.11
-
8
-
-
34247477207
-
Hypoxia inducible factor-2alpha in cancer
-
Lofstedt T, et al. (2007) Hypoxia inducible factor-2alpha in cancer. Cell Cycle 6:919-926.
-
(2007)
Cell Cycle
, vol.6
, pp. 919-926
-
-
Lofstedt, T.1
-
9
-
-
11144222884
-
Prognostic impact of hypoxia-inducible factors 1alpha and 2alpha in colorectal cancer patients: Correlation with tumor angiogenesis and cyclooxygenase-2 expression
-
DOI 10.1158/1078-0432.CCR-0946-03
-
Yoshimura H, et al. (2004) Prognostic impact of hypoxia-inducible factors 1alpha and 2alpha in colorectal cancer patients: Correlation with tumor angiogenesis and cyclooxygenase-2 expression. Clin Cancer Res 10:8554-8560. (Pubitemid 40053424)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.24
, pp. 8554-8560
-
-
Yoshimura, H.1
Dhar, D.K.2
Kohno, H.3
Kubota, H.4
Fujii, T.5
Ueda, S.6
Kinugasa, S.7
Tachibana, M.8
Nagasue, N.9
-
10
-
-
33644747418
-
HIF-2alpha regulates Oct-4: Effects of hypoxia on stem cell function, embryonic development, and tumor growth
-
DOI 10.1101/gad.1399906
-
Covello KL, et al. (2006) HIF-2alpha regulates Oct-4: Effects of hypoxia on stem cell function, embryonic development, and tumor growth. Genes Dev 20:557-570. (Pubitemid 43345322)
-
(2006)
Genes and Development
, vol.20
, Issue.5
, pp. 557-570
-
-
Covello, K.L.1
Kehler, J.2
Yu, H.3
Gordan, J.D.4
Arsham, A.M.5
Hu, C.-J.6
Labosky, P.A.7
Simon, M.C.8
Keith, B.9
-
11
-
-
33745274488
-
Role of ETS transcription factors in the hypoxia-inducible factor-2 target gene selection
-
DOI 10.1158/0008-5472.CAN-05-3345
-
Aprelikova O, Wood M, Tackett S, Chandramouli GV, Barrett JC (2006) Role of ETS transcription factors in the hypoxia-inducible factor-2 target gene selection. Cancer Res 66:5641-5647. (Pubitemid 43927116)
-
(2006)
Cancer Research
, vol.66
, Issue.11
, pp. 5641-5647
-
-
Aprelikova, O.1
Wood, M.2
Tackett, S.3
Chandramouli, G.V.R.4
Barrett, J.C.5
-
12
-
-
9444283176
-
Differentiating the functional role of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha (EPAS-1) by the use of RNA interference: Erythropoietin is a HIF-2alpha target gene in Hep3B and Kelly cells
-
DOI 10.1096/fj.04-1640fje
-
Warnecke C, et al. (2004) Differentiating the functional role of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha (EPAS-1) by the use of RNA interference: Erythropoietin is a HIF-2alpha target gene in Hep3B and Kelly cells. FASEB J 18:1462-1464. (Pubitemid 39561615)
-
(2004)
FASEB Journal
, vol.18
, Issue.12
, pp. 1462-1464
-
-
Warnecke, C.1
Zaborowska, Z.2
Kurreck, J.3
Erdmann, V.A.4
Frei, U.5
Wiesener, M.6
Eckardt, K.-U.7
-
13
-
-
33748714735
-
The transcriptional activator hypoxia inducible factor 2 (HIF-2/EPAS-1) regulates the oxygen-dependent expression of erythropoietin in cortical astrocytes
-
DOI 10.1523/JNEUROSCI.2838-06.2006
-
Chavez JC, Baranova O, Lin J, Pichiule P (2006) The transcriptional activator hypoxia inducible factor 2 (HIF-2/EPAS-1) regulates the oxygen-dependent expression of erythropoietin in cortical astrocytes. J Neurosci 26:9471-9481. (Pubitemid 44396860)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.37
, pp. 9471-9481
-
-
Chavez, J.C.1
Baranova, O.2
Lin, J.3
Pichiule, P.4
-
14
-
-
34147124264
-
Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo
-
DOI 10.1172/JCI30117
-
Rankin EB, et al. (2007) Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo. J Clin Invest 117:1068-1077. (Pubitemid 46556763)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.4
, pp. 1068-1077
-
-
Rankin, E.B.1
Biju, M.P.2
Liu, Q.3
Unger, T.L.4
Rha, J.5
Johnson, R.S.6
Simon, M.C.7
Keith, B.8
Haase, V.H.9
-
15
-
-
34249704041
-
Hypoxia-inducible factor 2alpha regulates expression of the mitochondrial aconitase chaperone protein frataxin
-
DOI 10.1074/jbc.M611133200
-
Oktay Y, et al. (2007) Hypoxia-inducible factor 2alpha regulates expression of the mitochondrial aconitase chaperone protein frataxin. J Biol Chem 282:11750-11756. (Pubitemid 47100692)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.16
, pp. 11750-11756
-
-
Oktay, Y.1
Dioum, E.2
Matsuzaki, S.3
Ding, K.4
Yan, L.-J.5
Haller, R.G.6
Szweda, L.I.7
Garcia, J.A.8
-
16
-
-
0344826529
-
-/- mice
-
DOI 10.1038/ng1266
-
Scortegagna M, et al. (2003) Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice. Nat Genet 35:331-340. (Pubitemid 37486916)
-
(2003)
Nature Genetics
, vol.35
, Issue.4
, pp. 331-340
-
-
Scortegagna, M.1
Ding, K.2
Oktay, Y.3
Gaur, A.4
Thurmond, F.5
Yan, L.-J.6
Marck, B.T.7
Matsumoto, A.M.8
Shelton, J.M.9
Richardson, J.A.10
Bennet, M.J.11
Garcia, J.A.12
-
17
-
-
0029921939
-
2 receptors?
-
DOI 10.1016/S0163-7258(96)00094-0, PII S0163725896000940
-
Daval JL, Nicolas F, Doriat JF (1996) Adenosine physiology and pharmacology: How about A2 receptors? Pharmacol Ther 71:325-335. (Pubitemid 26366376)
-
(1996)
Pharmacology and Therapeutics
, vol.71
, Issue.3
, pp. 325-335
-
-
Daval, J.-L.1
Nicolas, F.2
Doriat, J.-F.3
-
19
-
-
0027320829
-
Adenosine stimulates proliferation of human endothelial cells in culture
-
Ethier MF, Chander V, Dobson JG, Jr (1993) Adenosine stimulates proliferation of human endothelial cells in culture. Am J Physiol 265:H131-H138.
-
(1993)
Am J Physiol
, vol.265
-
-
Ethier, M.F.1
Chander, V.2
Dobson Jr., J.G.3
-
21
-
-
0037155773
-
2B receptors in angiogenic factor regulation
-
DOI 10.1161/01.RES.0000012203.21416.14
-
Feoktistov I, et al. (2002) Differential expression of adenosine receptors in human endothelial cells: Role of A2B receptors in angiogenic factor regulation. Circ Res 90:531-538. (Pubitemid 34640902)
-
(2002)
Circulation Research
, vol.90
, Issue.5
, pp. 531-538
-
-
Feoktistov, I.1
Goldstein, A.E.2
Ryzhov, S.3
Zeng, D.4
Belardinelli, L.5
Voyno-Yasenetskaya, T.6
Biaggioni, I.7
-
22
-
-
0035008669
-
Beneficial effects of adenosine A(2a) agonist CGS-21680 in infarcted and stunned porcine myocardium
-
Lasley RD, Jahania MS, Mentzer RM, Jr (2001) Beneficial effects of adenosine A(2a) agonist CGS-21680 in infarcted and stunned porcine myocardium. Am J Physiol Heart Circ Physiol 280:H1660-H1666.
-
(2001)
Am J Physiol Heart Circ Physiol
, vol.280
-
-
Lasley, R.D.1
Jahania, M.S.2
Mentzer Jr., R.M.3
-
24
-
-
0034807951
-
2A adenosine receptor activation reduces skin pressure ulcer formation and inflammation
-
Peirce SM, Skalak TC, Rieger JM, Macdonald TL, Linden J (2001) Selective A(2A) adenosine receptor activation reduces skin pressure ulcer formation and inflammation. Am J Physiol Heart Circ Physiol 281:H67-H74. (Pubitemid 32911777)
-
(2001)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.281
, Issue.1
-
-
Peirce, S.M.1
Skalak, T.C.2
Rieger, J.M.3
Macdonald, T.L.4
Linden, J.5
-
25
-
-
0035463187
-
2A agonist, ATL-146e, reduces paralysis and apoptosis during rabbit spinal cord reperfusion
-
DOI 10.1067/mva.2001.117996
-
Cassada DC, et al. (2001) An adenosine A2A agonist, ATL-146e, reduces paralysis and apoptosis during rabbit spinal cord reperfusion. J Vasc Surg 34:482-488. (Pubitemid 33661182)
-
(2001)
Journal of Vascular Surgery
, vol.34
, Issue.3
, pp. 482-488
-
-
Cassada, D.C.1
Tribble, C.G.2
Laubach, V.E.3
Nguyen, B.-N.4
Rieger, J.M.5
Linden, J.6
Kaza, A.K.7
Long, S.M.8
Kron, I.L.9
Kern, J.A.10
-
26
-
-
0035041314
-
2A receptor stimulation reduces inflammation and neointimal growth in a murine carotid ligation model
-
McPherson JA, et al. (2001) Adenosine A(2A) receptor stimulation reduces inflammation and neointimal growth in a murine carotid ligation model. Arterioscler Thromb Vasc Biol 21:791-796. (Pubitemid 32448770)
-
(2001)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.21
, Issue.5
, pp. 791-796
-
-
McPherson, J.A.1
Barringhaus, K.G.2
Bishop, G.G.3
Sanders, J.M.4
Rieger, J.M.5
Hesselbacher, S.E.6
Gimple, L.W.7
Powers, E.R.8
Macdonald, T.9
Sullivan, G.10
Linden, J.11
Sarembock, I.J.12
-
27
-
-
0032589671
-
Selective adenosine-A(2A) activation reduces lung reperfusion injury following transplantation
-
DOI 10.1016/S1053-2498(99)00066-2, PII S1053249899000662
-
Ross SD, et al. (1999) Selective adenosine-A2A activation reduces lung reperfusion injury following transplantation. J Heart Lung Transplant 18:994-1002. (Pubitemid 29505488)
-
(1999)
Journal of Heart and Lung Transplantation
, vol.18
, Issue.10
, pp. 994-1002
-
-
Ross, S.D.1
Tribble, C.G.2
Linden, J.3
Gangemi, J.J.4
Lanpher, B.C.5
Wang, A.Y.6
Kron, I.L.7
-
28
-
-
0035924320
-
Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage
-
DOI 10.1038/414916a
-
Ohta A, Sitkovsky M (2001) Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage. Nature 414:916-920. (Pubitemid 34024743)
-
(2001)
Nature
, vol.414
, Issue.6866
, pp. 916-920
-
-
Ohta, A.1
Sitkovsky, M.2
-
29
-
-
0033864021
-
Adenosine A(2A) and A(2B) receptors in cultured human and porcine coronary artery endothelial cells
-
Olanrewaju HA, Qin W, Feoktistov I, Scemama JL, Mustafa SJ (2000) Adenosine A(2A) and A(2B) receptors in cultured human and porcine coronary artery endothelial cells. Am J Physiol Heart Circ Physiol 279:H650-H656. (Pubitemid 30672777)
-
(2000)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.279
, Issue.2
-
-
Olanrewaju, H.A.1
Qin, W.2
Feoktistov, I.3
Scemama, J.-L.4
Mustafa, S.J.5
-
30
-
-
17844388561
-
2A receptor stimulation increases angiogenesis by down-regulating production of the antiangiogenic matrix protein thrombospondin 1
-
DOI 10.1124/mol.104.007807
-
Desai A, et al. (2005) Adenosine A2A receptor stimulation increases angiogenesis by down-regulating production of the antiangiogenic matrix protein thrombospondin 1. Mol Pharmacol 67:1406-1413. (Pubitemid 40594139)
-
(2005)
Molecular Pharmacology
, vol.67
, Issue.5
, pp. 1406-1413
-
-
Desai, A.1
Victor-Vega, C.2
Gadangi, S.3
Montesinos, M.C.4
Chu, C.C.5
Cronstein, B.N.6
-
31
-
-
0033991158
-
Escape of human solid tumors from T-cell recognition: Molecular mechanisms and functional significance
-
Marincola FM, Jaffee EM, Hicklin DJ, Ferrone S (2000) Escape of human solid tumors from T-cell recognition: Molecular mechanisms and functional significance. Adv Immunol 74:181-273.
-
(2000)
Adv Immunol
, vol.74
, pp. 181-273
-
-
Marincola, F.M.1
Jaffee, E.M.2
Hicklin, D.J.3
Ferrone, S.4
-
32
-
-
33947633432
-
From "Hellstrom Paradox" to anti-adenosinergic cancer immunotherapy
-
Lukashev D, Sitkovsky M, Ohta A (2007) From "Hellstrom Paradox" to anti-adenosinergic cancer immunotherapy. Purinergic Signal 3:129-134.
-
(2007)
Purinergic Signal
, vol.3
, pp. 129-134
-
-
Lukashev, D.1
Sitkovsky, M.2
Ohta, A.3
-
33
-
-
34547120458
-
Hypoxia-dependent anti-inflammatory pathways in protection of cancerous tissues
-
Lukashev D, Ohta A, Sitkovsky M (2007) Hypoxia-dependent anti-inflammatory pathways in protection of cancerous tissues. Cancer Metastasis Rev 26:273-279.
-
(2007)
Cancer Metastasis Rev
, vol.26
, pp. 273-279
-
-
Lukashev, D.1
Ohta, A.2
Sitkovsky, M.3
-
34
-
-
61349158530
-
T regulatory cells: Hypoxia-adenosinergic suppression and redirection of the immune response
-
Sitkovsky MV (2009) T regulatory cells: Hypoxia-adenosinergic suppression and redirection of the immune response. Trends Immunol 30:102-108.
-
(2009)
Trends Immunol
, vol.30
, pp. 102-108
-
-
Sitkovsky, M.V.1
-
35
-
-
15244342671
-
Stimulation of HIF-1alpha, HIF-2alpha, and VEGF by prolyl 4-hydroxylase inhibition in human lung endothelial and epithelial cells
-
DOI 10.1016/j.freeradbiomed.2004.12.004
-
Asikainen TM, et al. (2005) Stimulation of HIF-1alpha, HIF-2alpha, and VEGF by prolyl 4-hydroxylase inhibition in human lung endothelial and epithelial cells. Free Radic Biol Med 38:1002-1013. (Pubitemid 40386546)
-
(2005)
Free Radical Biology and Medicine
, vol.38
, Issue.8
, pp. 1002-1013
-
-
Asikainen, T.M.1
Ahmad, A.2
Schneider, B.K.3
Ho, W.-B.4
Arend, M.5
Brenner, M.6
Gunzler, V.7
White, C.W.8
-
36
-
-
11144354993
-
2A receptor gene by molecular and bioinformatics analyses
-
DOI 10.1016/j.brainres.2003.11.072, PII S0006899304000575
-
Yu L, et al. (2004) Characterization of genomic organization of the adenosine A2A receptor gene by molecular and bioinformatics analyses. Brain Res 1000:156-173. (Pubitemid 38446500)
-
(2004)
Brain Research
, vol.1000
, Issue.1-2
, pp. 156-173
-
-
Yu, L.1
Frith, M.C.2
Suzuki, Y.3
Peterfreund, R.A.4
Gearan, T.5
Sugano, S.6
Schwarzschild, M.A.7
Weng, Z.8
Fink, J.S.9
Chen, J.-F.10
-
37
-
-
22344435841
-
Direct isolation and identification of promoters in the human genome
-
Kim TH, et al. (2005) Direct isolation and identification of promoters in the human genome. Genome Res 15:830-839.
-
(2005)
Genome Res
, vol.15
, pp. 830-839
-
-
Kim, T.H.1
-
38
-
-
0038664127
-
Identification and functional analysis of human transcriptional promoters
-
DOI 10.1101/gr.794803
-
Trinklein ND, Aldred SJ, Saldanha AJ, Myers RM (2003) Identification and functional analysis of human transcriptional promoters. Genome Res 13:308-312. (Pubitemid 36575778)
-
(2003)
Genome Research
, vol.13
, Issue.2
, pp. 308-312
-
-
Trinklein, N.D.1
Force Aldred, S.J.2
Saldanha, A.J.3
Myers, R.M.4
-
39
-
-
2442689337
-
2A receptor activation promotes wound neovascularization by stimulating angiogenesis and vasculogenesis
-
Montesinos MC, Shaw JP, Yee H, Shamamian P, Cronstein BN (2004) Adenosine A(2A) receptor activation promotes wound neovascularization by stimulating angiogenesis and vasculogenesis. Am J Pathol 164:1887-1892. (Pubitemid 38669338)
-
(2004)
American Journal of Pathology
, vol.164
, Issue.6
, pp. 1887-1892
-
-
Montesinos, M.C.1
Shaw, J.P.2
Yee, H.3
Shamamian, P.4
Cronstein, B.N.5
-
40
-
-
7244234161
-
2B angiogenic phenotype
-
DOI 10.1161/01.HYP.0000144800.21037.a5
-
Feoktistov I, et al. (2004) Hypoxia modulates adenosine receptors in human endothelial and smooth muscle cells toward an A2B angiogenic phenotype. Hypertension 44:649-654. (Pubitemid 39435234)
-
(2004)
Hypertension
, vol.44
, Issue.5
, pp. 649-654
-
-
Feoktistov, I.1
Ryzhov, S.2
Zhong, H.3
Goldstein, A.E.4
Matafonov, A.5
Zeng, D.6
Biaggioni, I.7
-
41
-
-
25144475141
-
Cobalt promotes angiogenesis via hypoxia-inducible factor and protects tubulointerstitium in the remnant kidney model
-
DOI 10.1038/labinvest.3700328, PII 3700328
-
Tanaka T, et al. (2005) Cobalt promotes angiogenesis via hypoxia-inducible factor and protects tubulointerstitium in the remnant kidney model. Lab Invest 85:1292-1307. (Pubitemid 41348643)
-
(2005)
Laboratory Investigation
, vol.85
, Issue.10
, pp. 1292-1307
-
-
Tanaka, T.1
Kojima, I.2
Ohse, T.3
Ingelfinger, J.R.4
Adler, S.5
Fujita, T.6
Nangaku, M.7
-
42
-
-
0031020884
-
Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells
-
Tian H, McKnight SL, Russell DW (1997) Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells. Genes Dev 11:72-82. (Pubitemid 27043825)
-
(1997)
Genes and Development
, vol.11
, Issue.1
, pp. 72-82
-
-
Tian, H.1
McKnight, S.L.2
Russell, D.W.3
-
43
-
-
0036773572
-
Airway and blood vessel interaction during lung development
-
DOI 10.1046/j.1469-7580.2002.00097.x
-
Hislop AA (2002) Airway and blood vessel interaction during lung development. J Anat 201:325-334. (Pubitemid 35244052)
-
(2002)
Journal of Anatomy
, vol.201
, Issue.4
, pp. 325-334
-
-
Hislop, A.A.1
-
44
-
-
34248384848
-
Bronchopulmonary dysplasia: Where have all the vessels gone? Roles of angiogenic growth factors in chronic lung disease
-
DOI 10.1164/rccm.200611-1660PP
-
Thebaud B, Abman SH (2007) Bronchopulmonary dysplasia: Where have all the vessels gone? Roles of angiogenic growth factors in chronic lung disease. Am J Respir Crit Care Med 175:978-985. (Pubitemid 46741748)
-
(2007)
American Journal of Respiratory and Critical Care Medicine
, vol.175
, Issue.10
, pp. 978-985
-
-
Thebaud, B.1
Abman, S.H.2
-
45
-
-
0028929803
-
Angiogenesis in cancer, vascular, rheumatoid and other disease
-
Folkman J (1995) Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1:27-31.
-
(1995)
Nat Med
, vol.1
, pp. 27-31
-
-
Folkman, J.1
-
46
-
-
35848938945
-
The N-terminal transactivation domain confers target gene specificity of hypoxia-inducible factors HIF-1alpha and HIF-2alpha
-
DOI 10.1091/mbc.E06-05-0419
-
Hu CJ, Sataur A, Wang L, Chen H, Simon MC (2007) The N-terminal transactivation domain confers target gene specificity of hypoxia-inducible factors HIF-1alpha and HIF-2alpha. Mol Biol Cell 18:4528-4542. (Pubitemid 350060179)
-
(2007)
Molecular Biology of the Cell
, vol.18
, Issue.11
, pp. 4528-4542
-
-
Hu, C.-J.1
Sataur, A.2
Wang, L.3
Chen, H.4
Simon, M.C.5
-
47
-
-
34247219188
-
Target gene selectivity of hypoxia-inducible factor-alpha in renal cancer cells is conveyed by post-DNA-binding mechanisms
-
DOI 10.1038/sj.bjc.6603675, PII 6603675
-
Lau KW, Tian YM, Raval RR, Ratcliffe PJ, Pugh CW (2007) Target gene selectivity of hypoxia-inducible factor-alpha in renal cancer cells is conveyed by post-DNA-binding mechanisms. Br J Cancer 96:1284-1292. (Pubitemid 46625064)
-
(2007)
British Journal of Cancer
, vol.96
, Issue.8
, pp. 1284-1292
-
-
Lau, K.W.1
Tian, Y.-M.2
Raval, R.R.3
Ratcliffe, P.J.4
Pugh, C.W.5
-
48
-
-
33845604971
-
HIF-dependent induction of adenosine A2B receptor in hypoxia
-
DOI 10.1096/fj.06-6419com
-
Kong T, Westerman KA, Faigle M, Eltzschig HK, Colgan SP (2006) HIF-dependent induction of adenosine A2B receptor in hypoxia. FASEB J 20:2242-2250. (Pubitemid 44953854)
-
(2006)
FASEB Journal
, vol.20
, Issue.13
, pp. 2242-2250
-
-
Kong, T.1
Westerman, K.A.2
Faigle, M.3
Eltzschig, H.K.4
Colgan, S.P.5
-
49
-
-
1542298858
-
Structural and functional characteristics of lung macro- And microvascular endothelial cell phenotypes
-
DOI 10.1016/j.mvr.2003.11.006, PII S002628620300116X
-
King J, et al. (2004) Structural and functional characteristics of lung macro- and microvascular endothelial cell phenotypes. Microvasc Res 67:139-151. (Pubitemid 38327000)
-
(2004)
Microvascular Research
, vol.67
, Issue.2
, pp. 139-151
-
-
King, J.1
Hamil, T.2
Creighton, J.3
Wu, S.4
Bhat, P.5
McDonald, F.6
Stevens, T.7
-
50
-
-
51649090078
-
Hypoxia-inducible factor-2 regulates vascular tumorigenesis in mice
-
Rankin EB, et al. (2008) Hypoxia-inducible factor-2 regulates vascular tumorigenesis in mice. Oncogene 27:5354-5358.
-
(2008)
Oncogene
, vol.27
, pp. 5354-5358
-
-
Rankin, E.B.1
-
51
-
-
49649115935
-
Hypoxia-inducible transcription factor-2alpha in endothelial cells regulates tumor neovascularization through activation of ephrin A1
-
Yamashita T, et al. (2008) Hypoxia-inducible transcription factor-2alpha in endothelial cells regulates tumor neovascularization through activation of ephrin A1. J Biol Chem 283:18926-18936.
-
(2008)
J Biol Chem
, vol.283
, pp. 18926-18936
-
-
Yamashita, T.1
-
52
-
-
0032945321
-
Adenosine agonists for the prevention of restenosis?
-
Martin PL (1999) Adenosine agonists for the prevention of restenosis? IDrugs 2:44-51. (Pubitemid 29064294)
-
(1999)
IDrugs
, vol.2
, Issue.1
, pp. 44-51
-
-
Martin, P.L.1
-
53
-
-
33746256457
-
2A adenosine receptor via a novel interacting protein, translin-associated protein X
-
DOI 10.1124/mol.105.021261
-
Sun CN, et al. (2006) Rescue of p53 blockage by the A(2A) adenosine receptor via a novel interacting protein, translin-associated protein X. Mol Pharmacol 70:454-466. (Pubitemid 44092306)
-
(2006)
Molecular Pharmacology
, vol.70
, Issue.2
, pp. 454-466
-
-
Sun, C.-N.1
Cheng, H.-C.2
Chou, J.-L.3
Lee, S.-Y.4
Lin, Y.-W.5
Lai, H.-L.6
Chen, H.-M.7
Chern, Y.8
-
54
-
-
0242266596
-
2A adenosine receptor ligands and proinflammatory cytokines induce PC 12 cell death through apoptosis
-
DOI 10.1016/j.bcp.2003.07.006
-
Trincavelli ML, et al. (2003) A(2A) adenosine receptor ligands and proinflammatory cytokines induce PC 12 cell death through apoptosis. Biochem Pharmacol 66:1953-1962. (Pubitemid 37352858)
-
(2003)
Biochemical Pharmacology
, vol.66
, Issue.10
, pp. 1953-1962
-
-
Trincavelli, M.L.1
Falleni, A.2
Chelli, B.3
Tuscano, D.4
Costa, B.5
Gremigni, V.6
Lucacchini, A.7
Martini, C.8
-
55
-
-
0041825195
-
2A receptors regulate oxidative stress formation in rat pheochromocytoma PC12 cells during serum deprivation
-
DOI 10.1016/S0304-3940(03)00860-7
-
Huang NK (2003) Adenosine A2A receptors regulate oxidative stress formation in rat pheochromocytoma PC12 cells during serum deprivation. Neurosci Lett 350:127-131. (Pubitemid 37101428)
-
(2003)
Neuroscience Letters
, vol.350
, Issue.2
, pp. 127-131
-
-
Huang, N.-K.1
-
56
-
-
0030614357
-
Identification of an A(2a) adenosine receptor domain specifically responsible for mediating short-term desensitization
-
DOI 10.1021/bi962290v
-
Palmer TM, Stiles GL (1997) Identification of an A2a adenosine receptor domain specifically responsible for mediating short-term desensitization. Biochemistry 36:832-838. (Pubitemid 27110963)
-
(1997)
Biochemistry
, vol.36
, Issue.4
, pp. 832-838
-
-
Palmer, T.M.1
Stiles, G.L.2
-
57
-
-
33748357735
-
A2A adenosine receptor protects tumors from antitumor T cells
-
DOI 10.1073/pnas.0605251103
-
Ohta A, et al. (2006) A2A adenosine receptor protects tumors from antitumor T cells. Proc Natl Acad Sci USA 103:13132-13137. (Pubitemid 44338928)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.35
, pp. 13132-13137
-
-
Ohta, A.1
Gorelik, E.2
Prasad, S.J.3
Ronchese, F.4
Lukashev, D.5
Wong, M.K.K.6
Huang, X.7
Caldwell, S.8
Liu, K.9
Smith, P.10
Chen, J.-F.11
Jackson, E.K.12
Apasov, S.13
Abrams, S.14
Sitkovsky, M.15
-
58
-
-
34447537888
-
Prognostic significance of HIF-2alpha/EPAS1 expression in hepatocellular carcinoma
-
Bangoura G, et al. (2007) Prognostic significance of HIF-2alpha/EPAS1 expression in hepatocellular carcinoma. World J Gastroenterol 13:3176-3182. (Pubitemid 47064579)
-
(2007)
World Journal of Gastroenterology
, vol.13
, Issue.23
, pp. 3176-3182
-
-
Bangoura, G.1
Liu, Z.-S.2
Qian, Q.3
Jiang, C.-Q.4
Yang, G.-F.5
Jing, S.6
-
59
-
-
20744445650
-
Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma
-
DOI 10.1128/MCB.25.13.5675-5686.2005
-
Raval RR, et al. (2005) Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma. Mol Cell Biol 25:5675-5686. (Pubitemid 40853601)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.13
, pp. 5675-5686
-
-
Raval, R.R.1
Lau, K.W.2
Tran, M.G.B.3
Sowter, H.M.4
Mandriota, S.J.5
Li, J.-L.6
Pugh, C.W.7
Maxwell, P.H.8
Harris, A.L.9
Ratcliffe, P.J.10
-
60
-
-
60549103097
-
Host-derived angiopoietin-2 affects early stages of tumor development and vessel maturation but is dispensable for later stages of tumor growth
-
Nasarre P, et al. (2009) Host-derived angiopoietin-2 affects early stages of tumor development and vessel maturation but is dispensable for later stages of tumor growth. Cancer Res 69:1324-1333.
-
(2009)
Cancer Res
, vol.69
, pp. 1324-1333
-
-
Nasarre, P.1
-
61
-
-
58149096963
-
Expression of angiogenesis-related genes regulates different steps in the process of tumor growth and metastasis in human urothelial cell carcinoma of the urinary bladder
-
Chikazawa M, Inoue K, Fukata S, Karashima T, Shuin T (2008) Expression of angiogenesis-related genes regulates different steps in the process of tumor growth and metastasis in human urothelial cell carcinoma of the urinary bladder. Pathobiology 75:335-345.
-
(2008)
Pathobiology
, vol.75
, pp. 335-345
-
-
Chikazawa, M.1
Inoue, K.2
Fukata, S.3
Karashima, T.4
Shuin, T.5
-
62
-
-
58149147369
-
Hypoxia-adenosinergic immunosuppression: Tumor protection by T regulatory cells and cancerous tissue hypoxia
-
Sitkovsky MV, Kjaergaard J, Lukashev D, Ohta A (2008) Hypoxia-adenosinergic immunosuppression: Tumor protection by T regulatory cells and cancerous tissue hypoxia. Clin Cancer Res 14:5947-5952.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 5947-5952
-
-
Sitkovsky, M.V.1
Kjaergaard, J.2
Lukashev, D.3
Ohta, A.4
-
63
-
-
0036469038
-
Asparagine hydroxylation of the HIF transactivation domain: A hypoxic switch
-
DOI 10.1126/science.1068592
-
Lando D, Peet DJ, Whelan DA, Gorman JJ, Whitelaw ML (2002) Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch. Science 295:858-861. (Pubitemid 34118367)
-
(2002)
Science
, vol.295
, Issue.5556
, pp. 858-861
-
-
Lando, D.1
Peet, D.J.2
Whelan, D.A.3
Gorman, J.J.4
Whitelaw, M.L.5
-
64
-
-
0035903468
-
Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation
-
DOI 10.1093/emboj/20.18.5197
-
Masson N, Willam C, Maxwell PH, Pugh CW, Ratcliffe PJ (2001) Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation. EMBO J 20:5197-5206. (Pubitemid 32910914)
-
(2001)
EMBO Journal
, vol.20
, Issue.18
, pp. 5197-5206
-
-
Masson, N.1
Willam, C.2
Maxwell, P.H.3
Pugh, C.W.4
Ratcliffe, P.J.5
-
65
-
-
0032478271
-
A simplified system for generating recombinant adenoviruses
-
DOI 10.1073/pnas.95.5.2509
-
He TC, et al. (1998) A simplified system for generating recombinant adenoviruses. Proc Natl Acad Sci USA 95:2509-2514. (Pubitemid 28145972)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.5
, pp. 2509-2514
-
-
He, T.-C.1
Zhou, S.2
Da Costa, L.T.3
Yu, J.4
Kinzler, K.W.5
Vogelstein, B.6
-
66
-
-
33644910703
-
Endothelial Akt activation by hyperoxia: Role in cell survival
-
Ahmad A, Ahmad S, Chang LY, Schaack J, White CW (2006) Endothelial Akt activation by hyperoxia: Role in cell survival. Free Radic Biol Med 40:1108-1118.
-
(2006)
Free Radic Biol Med
, vol.40
, pp. 1108-1118
-
-
Ahmad, A.1
Ahmad, S.2
Chang, L.Y.3
Schaack, J.4
White, C.W.5
-
67
-
-
0029063593
-
Efficient selection of recombinant adenoviruses by vectors that express beta-galactosidase
-
Schaack J, Langer S, Guo X (1995) Efficient selection of recombinant adenoviruses by vectors that express beta-galactosidase. J Virol 69:3920-3923.
-
(1995)
J Virol
, vol.69
, pp. 3920-3923
-
-
Schaack, J.1
Langer, S.2
Guo, X.3
|