Inhibition of hypoxia-induced increase of blood-brain barrier permeability by YC-1 through the antagonism of HIF-1α accumulation and VEGF expression

Molecular Pharmacology

Volumn 72, Issue 2, 2007, Pages 440-449

  Yeh, Wei Lan ^a   Lu, Dah Yuu ^a   Lin, Chun Jung ^a   Liou, Houng Chi ^a   Fu, Wen Mei ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

1 BENZYL 3 (5 HYDROXYMETHYL 2 FURYL)INDAZOLE; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MEMBRANE PROTEIN; MESSENGER RNA; UNCLASSIFIED DRUG; VASCULOTROPIN; ZONULAR OCCLUDENS 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN HYPOXIA; BRAIN ISCHEMIA; CELL CULTURE; CONTROLLED STUDY; DOWN REGULATION; DRUG ACTIVITY; ENDOTHELIUM CELL; HOMEOSTASIS; INHIBITION KINETICS; MEMBRANE PERMEABILITY; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION; TIGHT JUNCTION;

ANIMALS; BLOOD-BRAIN BARRIER; CELL HYPOXIA; CELLS, CULTURED; CYCLIC GMP; CYCLIC GMP-DEPENDENT PROTEIN KINASES; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INDAZOLES; ISCHEMIA; MALE; MEMBRANE PROTEINS; PERMEABILITY; PHOSPHOPROTEINS; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 34547180418     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.107.036418     Document Type: Article

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