Hypoxia-inducible factor-1 signalling promotes goblet cell hyperplasia in airway epithelium

Journal of Pathology

Volumn 224, Issue 2, 2011, Pages 203-211

  Polosukhin, Vasiliy V ^a   Cates, Justin M ^b   Lawson, William E ^a,d   Milstone, Aaron P ^a   Matafonov, Anton G ^b   Massion, Pierre P ^a,c,d   Lee, Jae Woo ^e   Randell, Scott H ^f,g   Blackwell, Timothy S ^a,c,d  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d DEPARTMENT OF VETERANS AFFAIRS   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

bronchial epithelium; cell differentiation; chronic obstructive pulmonary disease; mucous cell hyperplasia; mucus

Indexed keywords

CARBONATE DEHYDRATASE IX; EPIDERMAL GROWTH FACTOR RECEPTOR; HYPOXIA INDUCIBLE FACTOR 1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RAS PROTEIN; STABILIZING AGENT; STAT6 PROTEIN; UNCLASSIFIED DRUG; [(4 BIPHENYLYLSULPHONYL)AMINO] N HYDROXY 3 PHENYLPROPIONAMIDE;

ADULT; AIRWAY REMODELING; ARTICLE; CELL DIFFERENTIATION; CELL HYPERPLASIA; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; FEMALE; GOBLET CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RESPIRATORY EPITHELIUM; SIGNAL TRANSDUCTION; SMOKING;

EID: 79955868497     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2863     Document Type: Article

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