Activation of hypoxia-inducible factors in hyperoxia through prolyl 4-hydroxylase blockade in cells and explants of primate lung

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 29, 2005, Pages 10212-10217

  Asikainen, Tuna M ^a   Schneider, Barbara K ^a   Walen, Nahid S ^b   Clyman, Ronald I ^b   Ho, Wen Bin ^c   Flippin, Lee A ^c   Günzler, Volkmar ^c   White, Carl W ^a  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c FIBROGEN INC   (United States)

Author keywords

Alveolization; Angiogenesis; Bronchopulmonary dysplasia; Prematurity

Indexed keywords

ANGIOGENIC FACTOR; BIOLOGICAL FACTOR; CD31 ANTIGEN; DIMETHYLOXALOYLGLYCINE; ENZYME INHIBITOR; FG 4095; GLYCINE DERIVATIVE; HYPOXIA INDUCIBLE FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE 2; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE 3; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

ADULT; ANGIOGENESIS; ANIMAL CELL; ARTICLE; ARTIFICIAL VENTILATION; BABOON; CELL STRAIN; CELL STRAIN A549; CELLULAR DISTRIBUTION; ENDOTHELIUM CELL; EXPLANT; FETUS; GENE EXPRESSION; HUMAN; HUMAN CELL; HYPEROXIA; HYPOXIA; IN VITRO STUDY; LUNG; LUNG ALVEOLUS CELL; LUNG DEVELOPMENT; LUNG DYSPLASIA; MICROVASCULATURE; NONHUMAN; PREMATURITY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; RESPIRATORY DISTRESS SYNDROME; VASCULAR ENDOTHELIUM;

AMINO ACIDS, DICARBOXYLIC; ANALYSIS OF VARIANCE; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BLOTTING, WESTERN; ENDOTHELIAL CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; HUMANS; HYPEROXIA; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LUNG; NEOVASCULARIZATION, PHYSIOLOGIC; OXYGEN; PAPIO; POLYMERASE CHAIN REACTION; PROCOLLAGEN-PROLINE DIOXYGENASE; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; VASCULAR CELL ADHESION MOLECULE-1; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

PAPIO HAMADRYAS; PRIMATES;

EID: 22544442167     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0504520102     Document Type: Article

References (48)

1. Wood, S. M., Gleadle, J. M., Pugh, C. W., Hankinson, O. & Ratcliffe, P. J. (1996) J. Biol. Chem. 271, 15117-15123.
2. Hu, C. J., Wang, L. Y., Chodosh, L. A., Keith, B. & Simon, M. C. (2003) Mol. Cell. Biol. 23, 9361-9374.
3. Jaakkola, P., Mole, D. R., Tian, Y. M., Wilson, M. I., Gielbert, J., Gaskell, S. J., Kriegsheim, A., Hebestreit, H. F., Mukherji, M., Schofield, C. J., et al. (2001) Science 292, 468-472.
4. Ivan, M., Kondo, K., Yang, H., Kim, W., Valiando, J., Ohh, M., Salic, A., Asara, J. M., Lane, W. S. & Kaolin, W. G., Jr. (2001) Science 292, 464-468.
5. Epstein, A. C., Gleadle, J. M., McNeill, L. A., Hewitson, K. S., O'Rourke, J., Mole, D. R., Mukherji, M., Metzen, E., Wilson, M. I., Dhanda, A., et al. (2001) Cell 107, 43-54.
6. Bruick, R. K. & McKnight, S. L. (2001) Science 294, 1337-1340.
7. Hirsilä, M., Koivunen, P., Günzler, V., Kivirikko, K. I. & Myllyharju, J. (2003) J. Biol. Chem. 278, 30772-30780.
8. Lando, D., Peet, D. J., Whelan, D. A., Gorman, J. J. & Whitelaw, M. L. (2002) Science 295, 858-861.
9. Jeong, J. W., Bae, M. K., Ahn, M. Y., Kim, S. H., Sohn, T. K., Bae, M. H., Yoo, M. A., Song, E. J., Lee, K. J. & Kim, K. W. (2002) Cell 111, 709-720.
10. Cockman, M. E., Masson, N., Mole, D. R., Jaakkola, P., Chang, G. W., Clifford, S. C., Maher, E. R., Pugh, C. W., Ratcliffe, P. J. & Maxwell, P. H. (2000) J. Biol. Chem. 275, 25733-25741.
11. Stenmark, K. R. & Gebb, S. A. (2003) Am. J. Respir. Cell Mol. Biol. 28, 133-137.
12. van Tuyl, M., Liu, J., Wang, J., Kuliszewski, M., Tibboel, D. & Post, M. (2005) Am. J. Physiol. 288, L167-L178.
13. Jobe, A. H. & Bancalari, E. (2001) Am. J. Respir. Crit. Care Med. 163, 1723-1729.
14. Jakkula, M., Le Cras, T. D., Gebb, S., Hirth, K. P., Tuder, R. M., Voelkel, N. F. & Abman, S. H. (2000) Am. J. Physiol. 279, L600-L607.
15. Bhatt, A. J., Pryhuber, G. S., Huyck, H., Watkins, R. H., Metlay, L. A. & Maniscalco, W. M. (2001) Am. J. Respir. Crit. Care Med. 164, 1971-1980.
16. Coalson, J. J., Winter, V. T., Siler-Khodr, T. & Yoder, B. A. (1999) Am. J. Respir. Crit. Care Med. 160, 1333-1346.
17. Lassus, P., Turanlahti, M., Heikkilä, P., Andersson, L. C., Nupponen, I., Sarnesto, A. & Andersson, S. (2001) Am. J. Respir. Crit. Care Med. 164, 1981-1987.
18. Pugh, C. W. & Ratcliffe, P. J. (2003) Nat. Med. 9, 677-684.
19. Forsythe, J. A., Jiang, B. H., Iyer, N. V., Agani, F., Leung, S. W., Koos, R. D. & Semenza, G. L. (1996) Mol. Cell. Biol. 16, 4604-4613.
20. Hosford, G. E. & Olson, D. M. (2003) Am. J. Physiol. 285, L161-L168.
21. Asikainen, T. M., Ahmad, A., Schneider, B. K., Ho, W.-B., Arend, M., Brenner, M., Günzler, V. & White, C. W. (2005) Free Radic. Biol. Med. 38, 1002-1013.
22. Das, K. C., Guo, X. L. & White, C. W. (1999) Am. J. Physiol. 276, L530-L539.
23. Waleh, N., Kajino, H., Marrache, A. M., Ginzinger, D., Roman, C., Seidner, S. R., Moss, T. J., Fouron, J. C., Vazquez-Tello, A., Chemtob, S., et al. (2004) Circulation 110, 2326-2332.
24. D'Angelo, G., Duplan, E., Boyer, N., Vigne, P. & Frelin, C. (2003) J. Biol. Chem. 278, 38183-38187.
25. Marxsen, J. H., Stengel, P., Doege, K., Heikkinen, P., Jokilehto, T., Wagner, T., Jelkmann, W., Jaakkola, P. & Metzen, E. (2004) Biochem. J. 381, 761-767.
26. Dalgard, C. L., Lu, H., Mohyeldin, A. & Verma, A. (2004) Biochem. J. 380, 419-424.
27. Appelhoff, R. J., Tian, Y. M., Raval, R. R., Turley, H., Harris, A. L., Pugh, C. W., Ratcliffe, P. J. & Gleadle, J. M. (2004) J. Biol. Chem. 279, 38458-38465.
28. Berra, E., Benizri, E., Ginouves, A., Volmat, V., Roux, D. & Pouyssegur, J. (2003) EMBO J. 22, 4082-4090.
29. Koivunen, P., Hirsilä, M., Günzler, V., Kivirikko, K. I. & Myllyharju, J. (2004) J. Biol. Chem. 279, 9899-9904.
30. Fong, G. H., Rossant, J., Gertsenstein, M. & Breitman, M. L. (1995) Nature 376, 66-70.
31. Shalaby, F., Rossant, J., Yamaguchi, T. P., Gertsenstein, M., Wu, X. F., Breitman, M. L. & Schuh, A. C. (1995) Nature 376, 62-66.
32. Ferrara, N., Gerber, H. P. & LeCouter, J. (2003) Nat. Med. 9, 669-676.
33. Rahimi, N., Dayanir, V. & Lashkari, K. (2000) J. Biol. Chem. 275, 16986-16992.
34. Hiratsuka, S., Maru, Y., Okada, A., Seiki, M., Noda, T. & Shibuya, M. (2001) Cancer Res. 61, 1207-1213.
35. Meyer, R. D., Singh, A., Majnoun, F., Latz, C., Lashkari, K. & Rahimi, N. (2004) Oncogene 23, 5523-5531.
36. Bussolati, B., Dunk, C., Grohman, M., Kontos, C. D., Mason, J. & Ahmed, A. (2001) Am. J. Pathol 159, 993-1008.
37. Gerber, H. P., Condorelli, F., Park, J. & Ferrara, N. (1997) J. Biol. Chem. 272, 23659-23667.
38. Tuder, R. M., Flook, B. E. & Voelkel, N. F. (1995) J. Clin. Invest. 95, 1798-1807.
39. Brogi, E., Schatteman, G., Wu, T., Kim, E. A., Varticovski, L., Keyt, B. & Isner, J. M. (1996) J. Clin. Invest. 97, 469-476.
40. Duval, M., Bedard-Goulet, S., Delisle, C. & Gratton, J. P. (2003) J. Biol. Chem. 278, 20091-20097.
41. Fulton, D., Babbitt, R., Zoellner, S., Fontana, J., Acevedo, L., McCabe, T. J., Iwakiri, Y. & Sessa, W. C. (2004) J. Biol. Chem. 279, 30349-30357.
42. Kanda, S., Miyata, Y. & Kanetake, H. (2004) J. Biol. Chem. 279, 4007-4016.
43. Le Cras, T. D., Spitzmiller, R. E., Albertine, K. H., Greenberg, J. M., Whitsett, J. A. & Akeson, A. L. (2004) Am. J. Physiol. 287, L134-L142.
44. Kaner, R. J., Ladetto, J. V., Singh, R., Fukuda, N., Matthay, M. A. & Crystal, R. G. (2000) Am. J. Respir. Cell Mol. Biol. 22, 657-664.
45. Akeson, A. L., Greenberg, J. M., Cameron, J. E., Thompson, F. Y., Brooks, S. K., Wiginton, D. & Whitsett, J. A. (2003) Dev. Biol. 264, 443-455.
46. Elson, D. A., Thurston, G., Huang, L. E., Ginzinger, D. G., McDonald, D. M., Johnson, R. S. & Arbeit, J. M. (2001) Genes Dev. 15, 2520-2532.
47. Larcher, F., Murillas, R., Bolontrade, M., Conti, C. J. & Jorcano, J. L. (1998) Oncogene 17, 303-311.
48. Thurston, G., Suri, C., Smith, K., McClain, J., Sato, T. N., Yancopoulos, G. D. & McDonald, D. M. (1999) Science 286, 2511-2514.