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Volumn 31, Issue 5, 2011, Pages 1054-1065

Increased Akt-mTOR signaling in lung epithelium is associated with respiratory distress syndrome in mice

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 2ALPHA; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE B; RAPAMYCIN; VASCULOTROPIN;

EID: 79952265832     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00732-10     Document Type: Article
Times cited : (26)

References (34)
  • 1
    • 1042279522 scopus 로고    scopus 로고
    • Vascular endothelial growth factor activates PI3K/Akt/forkhead signaling in endothelial cells
    • Abid, M. R., et al. 2004. Vascular endothelial growth factor activates PI3K/Akt/forkhead signaling in endothelial cells. Arterioscler. Thromb. Vasc. Biol. 24:294-300.
    • (2004) Arterioscler. Thromb. Vasc. Biol. , vol.24 , pp. 294-300
    • Abid, M.R.1
  • 2
    • 52449121729 scopus 로고    scopus 로고
    • Gestational diabetes mellitus: Postpartum opportunities for the diagnosis and prevention of type 2 diabetes mellitus
    • Bentley-Lewis, R., S. Levkoff, A. Stuebe, and E. W. Seely. 2008. Gestational diabetes mellitus: postpartum opportunities for the diagnosis and prevention of type 2 diabetes mellitus. Nat. Clin. Pract. Endocrinol. Metab. 4:552-558.
    • (2008) Nat. Clin. Pract. Endocrinol. Metab. , vol.4 , pp. 552-558
    • Bentley-Lewis, R.1    Levkoff, S.2    Stuebe, A.3    Seely, E.W.4
  • 4
    • 0035983324 scopus 로고    scopus 로고
    • Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice
    • Compernolle, V., et al. 2002. Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice. Nat. Med. 8:702-710.
    • (2002) Nat. Med. , vol.8 , pp. 702-710
    • Compernolle, V.1
  • 5
    • 20444442419 scopus 로고    scopus 로고
    • Effect of treatment of gestational diabetes mellitus on pregnancy outcomes
    • Crowther, C. A., et al. 2005. Effect of treatment of gestational diabetes mellitus on pregnancy outcomes. N. Engl. J. Med. 352:2477-2486.
    • (2005) N. Engl. J. Med. , vol.352 , pp. 2477-2486
    • Crowther, C.A.1
  • 6
    • 33749440900 scopus 로고    scopus 로고
    • Calcineurin/Nfat signaling is required for perinatal lung maturation and function
    • Dave, V., et al. 2006. Calcineurin/Nfat signaling is required for perinatal lung maturation and function. J. Clin. Invest. 116:2597-2609.
    • (2006) J. Clin. Invest. , vol.116 , pp. 2597-2609
    • Dave, V.1
  • 7
    • 40649120115 scopus 로고    scopus 로고
    • Conditional deletion of Pten causes bronchiolar hyperplasia
    • Dave, V., et al. 2008. Conditional deletion of Pten causes bronchiolar hyperplasia. Am. J. Respir. Cell Mol. Biol. 38:337-345.
    • (2008) Am. J. Respir. Cell Mol. Biol. , vol.38 , pp. 337-345
    • Dave, V.1
  • 8
    • 0026660556 scopus 로고
    • Insulin regulation of messenger ribonucleic acid for the surfactant-associated proteins in human fetal lung in vitro
    • Dekowski, S. A., and J. M. Snyder. 1992. Insulin regulation of messenger ribonucleic acid for the surfactant-associated proteins in human fetal lung in vitro. Endocrinology 131:669-676.
    • (1992) Endocrinology , vol.131 , pp. 669-676
    • Dekowski, S.A.1    Snyder, J.M.2
  • 9
    • 0037062234 scopus 로고    scopus 로고
    • Type 2 diabetes in pregnancy: A growing concern
    • Feig, D. S., and V. A. Palda. 2002. Type 2 diabetes in pregnancy: a growing concern. Lancet 359:1690-1692.
    • (2002) Lancet , vol.359 , pp. 1690-1692
    • Feig, D.S.1    Palda, V.A.2
  • 10
    • 0026717663 scopus 로고
    • Surfactant protein A expression is delayed in fetuses of streptozotocin-treated rats
    • Guttentag, S. H., D. S. Phelps, W. Stenzel, J. B. Warshaw, and J. Floros. 1992. Surfactant protein A expression is delayed in fetuses of streptozotocin-treated rats. Am. J. Physiol. 262:L489-L494.
    • (1992) Am. J. Physiol. , vol.262
    • Guttentag, S.H.1    Phelps, D.S.2    Stenzel, W.3    Warshaw, J.B.4    Floros, J.5
  • 11
    • 0026904365 scopus 로고
    • Delayed hydrophobic surfactant protein (SP-B, SP-C) expression in fetuses of streptozotocin-treated rats
    • Guttentag, S. H., D. S. Phelps, J. B. Warshaw, and J. Floros. 1992. Delayed hydrophobic surfactant protein (SP-B, SP-C) expression in fetuses of streptozotocin-treated rats. Am. J. Respir. Cell Mol. Biol. 7:190-197.
    • (1992) Am. J. Respir. Cell Mol. Biol. , vol.7 , pp. 190-197
    • Guttentag, S.H.1    Phelps, D.S.2    Warshaw, J.B.3    Floros, J.4
  • 12
    • 0034996563 scopus 로고    scopus 로고
    • Surfactant in respiratory distress syndrome and lung injury
    • Hallman, M., V. Glumoff, and M. Ramet. 2001. Surfactant in respiratory distress syndrome and lung injury. Comp. Biochem. Physiol. Part A 129:287-294.
    • (2001) Comp. Biochem. Physiol. Part A , vol.129 , pp. 287-294
    • Hallman, M.1    Glumoff, V.2    Ramet, M.3
  • 13
    • 0036789574 scopus 로고    scopus 로고
    • Regulation of hypoxia-inducible factor 1α expression and function by the mammalian target of rapamycin
    • Hudson, C. C., et al. 2002. Regulation of hypoxia-inducible factor 1α expression and function by the mammalian target of rapamycin. Mol. Cell. Biol. 22:7004-7014.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 7004-7014
    • Hudson, C.C.1
  • 16
    • 0036829025 scopus 로고    scopus 로고
    • Regulation of angiogenesis by glycogen synthase kinase-3β
    • Kim, H. S., et al. 2002. Regulation of angiogenesis by glycogen synthase kinase-3β. J. Biol. Chem. 277:41888-41896.
    • (2002) J. Biol. Chem. , vol.277 , pp. 41888-41896
    • Kim, H.S.1
  • 17
    • 0032967046 scopus 로고    scopus 로고
    • Expression of LKB1 and PTEN tumor suppressor genes during mouse embryonic development
    • Luukko, K., A. Ylikorkala, M. Tiainen, and T. P. Makela. 1999. Expression of LKB1 and PTEN tumor suppressor genes during mouse embryonic development. Mech. Dev. 83:187-190.
    • (1999) Mech. Dev. , vol.83 , pp. 187-190
    • Luukko, K.1    Ylikorkala, A.2    Tiainen, M.3    Makela, T.P.4
  • 18
    • 0033615639 scopus 로고    scopus 로고
    • Generation of a dominant-negative mutant of endothelial PAS domain protein 1 by deletion of a potent C-terminal transactivation domain
    • Maemura, K., et al. 1999. Generation of a dominant-negative mutant of endothelial PAS domain protein 1 by deletion of a potent C-terminal transactivation domain. J. Biol. Chem. 274:31565-31570.
    • (1999) J. Biol. Chem. , vol.274 , pp. 31565-31570
    • Maemura, K.1
  • 19
    • 33744779671 scopus 로고    scopus 로고
    • Neonatal respiratory distress syndrome
    • DOI 10.1016/S0140-6736(06)68820-X, PII S014067360668820X
    • Montan, S., and S. Arulkumaran. 2006. Neonatal respiratory distress syndrome. Lancet 367:1878-1879. (Pubitemid 43831978)
    • (2006) Lancet , vol.367 , Issue.9526 , pp. 1878-1879
    • Montan, S.1    Arulkumaran, S.2
  • 20
    • 57849135041 scopus 로고    scopus 로고
    • RtTA toxicity limits the usefulness of the SP-C-rtTA transgenic mouse
    • Morimoto, M., and R. Kopan. 2009. rtTA toxicity limits the usefulness of the SP-C-rtTA transgenic mouse. Dev. Biol. 325:171-178.
    • (2009) Dev. Biol. , vol.325 , pp. 171-178
    • Morimoto, M.1    Kopan, R.2
  • 22
    • 0014208018 scopus 로고
    • Pulmonary disease following respirator therapy of hyaline-membrane disease. Bronchopulmonary dysplasia
    • Northway, W. H., Jr., R. C. Rosan, and D. Y. Porter. 1967. Pulmonary disease following respirator therapy of hyaline-membrane disease. Bronchopulmonary dysplasia. N. Engl. J. Med. 276:357-368.
    • (1967) N. Engl. J. Med. , vol.276 , pp. 357-368
    • Northway Jr., W.H.1    Rosan, R.C.2    Porter, D.Y.3
  • 23
    • 0036677403 scopus 로고    scopus 로고
    • Early restriction of peripheral and proximal cell lineages during formation of the lung
    • Perl, A. K., S. E. Wert, A. Nagy, C. G. Lobe, and J. A. Whitsett. 2002. Early restriction of peripheral and proximal cell lineages during formation of the lung. Proc. Natl. Acad. Sci. U. S. A. 99:10482-10487.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 10482-10487
    • Perl, A.K.1    Wert, S.E.2    Nagy, A.3    Lobe, C.G.4    Whitsett, J.A.5
  • 25
    • 23644439061 scopus 로고    scopus 로고
    • Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure
    • Shiojima, I., et al. 2005. Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure. J. Clin. Invest. 115:2108-2118.
    • (2005) J. Clin. Invest. , vol.115 , pp. 2108-2118
    • Shiojima, I.1
  • 26
    • 0037020157 scopus 로고    scopus 로고
    • Akt signaling mediates postnatal heart growth in response to insulin and nutritional status
    • Shiojima, I., et al. 2002. Akt signaling mediates postnatal heart growth in response to insulin and nutritional status. J. Biol. Chem. 277:37670-37677.
    • (2002) J. Biol. Chem. , vol.277 , pp. 37670-37677
    • Shiojima, I.1
  • 27
    • 15544380502 scopus 로고    scopus 로고
    • Lung vascular development: Implications for the pathogenesis of bronchopulmonary dysplasia
    • Stenmark, K. R., and S. H. Abman. 2005. Lung vascular development: implications for the pathogenesis of bronchopulmonary dysplasia. Annu. Rev. Physiol. 67:623-661.
    • (2005) Annu. Rev. Physiol. , vol.67 , pp. 623-661
    • Stenmark, K.R.1    Abman, S.H.2
  • 28
    • 33244464562 scopus 로고    scopus 로고
    • Critical nodes in signalling pathways: Insights into insulin action
    • Taniguchi, C. M., B. Emanuelli, and C. R. Kahn. 2006. Critical nodes in signalling pathways: insights into insulin action. Nat. Rev. Mol. Cell Biol. 7:85-96.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 85-96
    • Taniguchi, C.M.1    Emanuelli, B.2    Kahn, C.R.3
  • 29
    • 0034697322 scopus 로고    scopus 로고
    • Conditional expression of fibroblast growth factor-7 in the developing and mature lung
    • Tichelaar, J. W., W. Lu, and J. A. Whitsett. 2000. Conditional expression of fibroblast growth factor-7 in the developing and mature lung. J. Biol. Chem. 275:11858-11864.
    • (2000) J. Biol. Chem. , vol.275 , pp. 11858-11864
    • Tichelaar, J.W.1    Lu, W.2    Whitsett, J.A.3
  • 30
    • 0034004440 scopus 로고    scopus 로고
    • The molecular basis of lung morphogenesis
    • Warburton, D., et al. 2000. The molecular basis of lung morphogenesis. Mech. Dev. 92:55-81.
    • (2000) Mech. Dev. , vol.92 , pp. 55-81
    • Warburton, D.1
  • 31
    • 0037180829 scopus 로고    scopus 로고
    • Hydrophobic surfactant proteins in lung function and disease
    • Whitsett, J. A., and T. E. Weaver. 2002. Hydrophobic surfactant proteins in lung function and disease. N. Engl. J. Med. 347:2141-2148.
    • (2002) N. Engl. J. Med. , vol.347 , pp. 2141-2148
    • Whitsett, J.A.1    Weaver, T.E.2
  • 32
    • 68149169793 scopus 로고    scopus 로고
    • Rapamycin inhibition of the Akt/mTOR pathway blocks select stages of VEGF-A164-driven angiogenesis, in part by blocking S6Kinase
    • Xue, Q., et al. 2009. Rapamycin inhibition of the Akt/mTOR pathway blocks select stages of VEGF-A164-driven angiogenesis, in part by blocking S6Kinase. Arterioscler. Thromb. Vasc. Biol. 29:1172-1178.
    • (2009) Arterioscler. Thromb. Vasc. Biol. , vol.29 , pp. 1172-1178
    • Xue, Q.1
  • 33
    • 34948850396 scopus 로고    scopus 로고
    • Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice
    • Yanagi, S., et al. 2007. Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice. J. Clin. Invest. 117:2929-2940.
    • (2007) J. Clin. Invest. , vol.117 , pp. 2929-2940
    • Yanagi, S.1
  • 34
    • 46249127489 scopus 로고    scopus 로고
    • A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration
    • Zhang, Y., et al. 2008. A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration. Nat. Genet. 40:862-870.
    • (2008) Nat. Genet. , vol.40 , pp. 862-870
    • Zhang, Y.1


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