Inflammatory levels of nitric oxide inhibit airway epithelial cell migration by inhibition of the kinase ERK1/2 and activation of hypoxia-inducible factor-1α

Journal of Biological Chemistry

Volumn 283, Issue 26, 2008, Pages 17919-17928

  Bove, Peter F ^a   Hristova, Milena ^a   Wesley, Umadevi V ^b   Olson, Nels ^a   Lounsbury, Karen M ^b   Van Der Vliet, Albert ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF VERMONT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CHLORINE COMPOUNDS; COBALT; CYTOLOGY; ENZYME ACTIVITY; GENE EXPRESSION; MAINTENANCE; NITRIC OXIDE; NUCLEIC ACIDS; PATHOLOGY; POLARIZATION; RNA; STABILIZATION; TRANSITION METALS;

ACTIVATED PROTEIN KINASES; AIRWAY EPITHELIAL CELL MIGRATIONS; AIRWAY INFLAMMATIONS; CELL MIGRATIONS; CELL TRANSFECTIONS; COBALT CHLORIDES; DEPHOSPHORYLATION; EPITHELIAL CELL MIGRATIONS; EPITHELIAL FUNCTIONS; EXTRACELLULAR SIGNALS; GENE EXPRESSION PROFILES; HUMAN BRONCHIAL EPITHELIAL CELLS; IN VITRO; INFLAMMATORY CONDITIONS; INJURY MODELS; LUNG CELLS; MITOGEN; NANOMOLAR LEVELS; NEGATIVE REGULATORS; NO DONORS; REGULATED KINASES; SIGNALING PATHWAYS; SYNTHASE; SYNTHESIS OF; WOUND CLOSURES; WOUND REPAIRS;

ACTIVATION ANALYSIS;

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; COBALT CHLORIDE; DIETHYLENETRIAMINE; DIETHYLENETRIAMINE NONOATE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INDUCIBLE NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; NITRIC OXIDE; NITRIC OXIDE DONOR; PROTEIN P53; UNCLASSIFIED DRUG; HIF1A PROTEIN, HUMAN; SMALL INTERFERING RNA; VASCULOTROPIN A;

ARTICLE; BRONCHUS MUCOSA; CELL DAMAGE; CELL MEMBRANE PERMEABILITY; CELL MIGRATION; CELL TYPE; DEPHOSPHORYLATION; ENZYME ACTIVATION; ENZYME INHIBITION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IN VITRO SELECTION; MIGRATION INHIBITION; OXIDATIVE STRESS; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; RESPIRATORY TRACT INFLAMMATION; WOUND CLOSURE; BIOLOGICAL MODEL; BIOSYNTHESIS; CELL MOTION; CYTOLOGY; EPITHELIUM CELL; INFLAMMATION; METABOLISM; WOUND HEALING;

CELL MOVEMENT; ENZYME ACTIVATION; EPITHELIAL CELLS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INFLAMMATION; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MODELS, BIOLOGICAL; NITRIC OXIDE; RNA, SMALL INTERFERING; TUMOR SUPPRESSOR PROTEIN P53; VASCULAR ENDOTHELIAL GROWTH FACTOR A; WOUND HEALING;

EID: 49649128881     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M709914200     Document Type: Article

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