How do immune cells overcome the blood-brain barrier in multiple sclerosis?

FEBS Letters

Volumn 585, Issue 23, 2011, Pages 3770-3780

  Larochelle, Catherine ^a,b   Alvarez, Jorge Ivan ^a   Prat, Alexandre ^a,b  

^a NOTRE DAME HOSPITAL   (Canada)

^b UNIVERSITY OF MONTREAL   (Canada)

Author keywords

Blood brain barrier; Cytokine; Leukocyte; Matrix metalloproteinase; Multiple Sclerosis; Reactive oxygen species

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; FAS LIGAND; GAMMA INTERFERON; GELATINASE A; GELATINASE B; GRANZYME B; HISTAMINE; HISTAMINE H1 RECEPTOR ANTAGONIST; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 21; INTERLEUKIN 21 RECEPTOR; INTERLEUKIN 22; INTERLEUKIN 23; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; NERVE GROWTH FACTOR; NEUROTROPHIN 3; ONCOSTATIN M; PERFORIN; PROTEIN ZO1; REACTIVE OXYGEN METABOLITE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; VASCULAR CELL ADHESION MOLECULE 1; VASCULOTROPIN;

ALLERGIC ENCEPHALOMYELITIS; ASTROCYTE; BLOOD BRAIN BARRIER; CD8+ T LYMPHOCYTE; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENDOTHELIUM CELL; EXTRACELLULAR MATRIX; HISTAMINE METABOLISM; HUMAN; LEUKOCYTE; LEUKOCYTE MIGRATION; MULTIPLE SCLEROSIS; NERVOUS SYSTEM INFLAMMATION; NEUROPROTECTION; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; RELAPSE; REVIEW; TH17 CELL; TIGHT JUNCTION;

ANIMALS; BLOOD-BRAIN BARRIER; CELL MOVEMENT; HUMANS; LYMPHOCYTES; MATRIX METALLOPROTEINASES; MULTIPLE SCLEROSIS; REACTIVE OXYGEN SPECIES;

EID: 81755179424     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2011.04.066     Document Type: Review

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