메뉴 건너뛰기




Volumn 64, Issue 1, 1996, Pages 63-69

Increased interleukin-6 mRNA expression in blood and cerebrospinal fluid mononuclear cells in multiple sclerosis

Author keywords

Autoimmunity; Cerebrospinal fluid; Cytokines; Interleukin 6; Multiple sclerosis

Indexed keywords

INTERLEUKIN 6; MESSENGER RNA;

EID: 0030042614     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/0165-5728(95)00155-7     Document Type: Article
Times cited : (82)

References (28)
  • 1
    • 0026319084 scopus 로고
    • Interleukin-6 levels in cerebrospinal fluid of patients with multiple sclerosis
    • Araga, S., Takai, H. and Takahashi, K. (1991) Interleukin-6 levels in cerebrospinal fluid of patients with multiple sclerosis. Jpn. J. Psych. Neurol. 45, 879-883.
    • (1991) Jpn. J. Psych. Neurol. , vol.45 , pp. 879-883
    • Araga, S.1    Takai, H.2    Takahashi, K.3
  • 2
    • 0026705725 scopus 로고
    • Sensitive mRNA detection using unfixed tissue: Combined radioactive and non-radioactive in situ hybridization histochemistry
    • Dagerlind, Å., Friberg, K., Bean, A.J. and Hökfelt, T. (1992) Sensitive mRNA detection using unfixed tissue: combined radioactive and non-radioactive in situ hybridization histochemistry. Histochemistry 98, 39-49.
    • (1992) Histochemistry , vol.98 , pp. 39-49
    • Dagerlind, Å.1    Friberg, K.2    Bean, A.J.3    Hökfelt, T.4
  • 3
    • 0015264390 scopus 로고
    • Large scale preparation of myelin basic protein from central nervous tissue of several animal species
    • Deibler, G.E., Martensson, R.E. and Kies, M.V. (1972) Large scale preparation of myelin basic protein from central nervous tissue of several animal species. Prep. Biochem. 2, 139-165.
    • (1972) Prep. Biochem. , vol.2 , pp. 139-165
    • Deibler, G.E.1    Martensson, R.E.2    Kies, M.V.3
  • 4
    • 0023678776 scopus 로고
    • Production of B cell stimulatory factor 2 and interferon-γ in the central nervous system during viral meningitis and encephalitis. Evaluation in a murine model infection and in patients
    • Frei, K., Leist, T.P., Meager, A., Gallo, P., Leppert, D., Zinkernagel, R.M. and Fontana, A. (1988) Production of B cell stimulatory factor 2 and interferon-γ in the central nervous system during viral meningitis and encephalitis. Evaluation in a murine model infection and in patients. J. Exp. Med. 168, 449-453.
    • (1988) J. Exp. Med. , vol.168 , pp. 449-453
    • Frei, K.1    Leist, T.P.2    Meager, A.3    Gallo, P.4    Leppert, D.5    Zinkernagel, R.M.6    Fontana, A.7
  • 5
    • 0024339530 scopus 로고
    • On the cellular source and function of interleukin 6 produced in the central nervous system in viral diseases
    • Frei, K., Malipiero, U.V., Leist, T.P., Zinkernagel, T.P., Schwab, M.E. and Fontana, A. (1989) On the cellular source and function of interleukin 6 produced in the central nervous system in viral diseases. Eur. J. Immunol. 19, 689-694.
    • (1989) Eur. J. Immunol. , vol.19 , pp. 689-694
    • Frei, K.1    Malipiero, U.V.2    Leist, T.P.3    Zinkernagel, T.P.4    Schwab, M.E.5    Fontana, A.6
  • 6
    • 0026074551 scopus 로고
    • Interleukin-6 is elevated in plasma in multiple sclerosis
    • Frei, K., Fredrikson, S., Fontana, A. and Link, H. (1991) Interleukin-6 is elevated in plasma in multiple sclerosis. J. Neuroimmunol. 31, 147-153.
    • (1991) J. Neuroimmunol. , vol.31 , pp. 147-153
    • Frei, K.1    Fredrikson, S.2    Fontana, A.3    Link, H.4
  • 7
    • 0025213321 scopus 로고
    • Interleukin 6 production in the central nervous system during experimental autoimmune encephalomyelitis
    • Gijbels, K., van Damme, J., Proost, P., Put, W., Carton, H. and Billiau, A. (1990) Interleukin 6 production in the central nervous system during experimental autoimmune encephalomyelitis. Eur. J. Immunol. 20, 233-235.
    • (1990) Eur. J. Immunol. , vol.20 , pp. 233-235
    • Gijbels, K.1    Van Damme, J.2    Proost, P.3    Put, W.4    Carton, H.5    Billiau, A.6
  • 8
    • 0022612860 scopus 로고
    • Purification of proteolipid protein and production of specific antiserum
    • Hampson, D.R. and Poduslo, S.E. (1986) Purification of proteolipid protein and production of specific antiserum. J. Immunol. 11, 117-129.
    • (1986) J. Immunol. , vol.11 , pp. 117-129
    • Hampson, D.R.1    Poduslo, S.E.2
  • 9
    • 0001668516 scopus 로고
    • Interleukin-6
    • A. Thomson (Ed.), Academic Press, London
    • Hirano, T. (1994) Interleukin-6. In: A. Thomson (Ed.), The Handbook of Cytokines. Academic Press, London, pp. 145-169.
    • (1994) The Handbook of Cytokines , pp. 145-169
    • Hirano, T.1
  • 10
    • 0026463068 scopus 로고
    • IL-6 and the T cell response
    • Houssiau, F. and van Snick, J. (1992) IL-6 and the T cell response. Res. Immunol. 143, 740-743.
    • (1992) Res. Immunol. , vol.143 , pp. 740-743
    • Houssiau, F.1    Van Snick, J.2
  • 11
    • 0023848694 scopus 로고
    • Elevated levels of the 26K human hybridoma growth factor (interleukin 6) in cerebrospinal fluid of patients with acute infection of the central nervous system
    • Houssiau, F.A., Bukasa, K., Sindic, C.J.M., van Damme, J. and van Snick, J. (1988) Elevated levels of the 26K human hybridoma growth factor (interleukin 6) in cerebrospinal fluid of patients with acute infection of the central nervous system. Clin. Exp. Immunol. 71, 320-323.
    • (1988) Clin. Exp. Immunol. , vol.71 , pp. 320-323
    • Houssiau, F.A.1    Bukasa, K.2    Sindic, C.J.M.3    Van Damme, J.4    Van Snick, J.5
  • 12
    • 0027506423 scopus 로고
    • Cytokine production by peripheral blood monocytes/macrophages in multiple sclerosis patients
    • Imamura, K., Suzumura, A., Hauashi, F. and Marunouschi, T. (1993) Cytokine production by peripheral blood monocytes/macrophages in multiple sclerosis patients. Acta Neurol. Scand. 87, 281-285.
    • (1993) Acta Neurol. Scand. , vol.87 , pp. 281-285
    • Imamura, K.1    Suzumura, A.2    Hauashi, F.3    Marunouschi, T.4
  • 13
    • 0021035886 scopus 로고
    • Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS)
    • Kurtzke, J.F. (1983) Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 33, 1444-1452.
    • (1983) Neurology , vol.33 , pp. 1444-1452
    • Kurtzke, J.F.1
  • 15
    • 0018926428 scopus 로고
    • Oligoclonal IgG and free light chains in multiple sclerosis demonstrated by thin-layer polyacrylamide gel isoelectric focusing and immunofixation
    • Laurenzi, M.A., Mavra, M., Kam-Hansen, S. and Link, H. (1980) Oligoclonal IgG and free light chains in multiple sclerosis demonstrated by thin-layer polyacrylamide gel isoelectric focusing and immunofixation. Ann. Neurol. 8, 241-247.
    • (1980) Ann. Neurol. , vol.8 , pp. 241-247
    • Laurenzi, M.A.1    Mavra, M.2    Kam-Hansen, S.3    Link, H.4
  • 16
    • 0015338997 scopus 로고
    • Oligoclonal immunoglobulin G in multiple sclerosis brains
    • Link, H. (1972) Oligoclonal immunoglobulin G in multiple sclerosis brains. J. Neurol. Sci. 16, 103-114.
    • (1972) J. Neurol. Sci. , vol.16 , pp. 103-114
    • Link, H.1
  • 17
    • 0008817389 scopus 로고
    • The cerebrospinal fluid in multiple sclerosis
    • M. Swash and J. Oxbury (Eds.), Churchill Livingstone, Edinburgh
    • Link, H. (1991) The cerebrospinal fluid in multiple sclerosis. In: M. Swash and J. Oxbury (Eds.), Textbook of Neurology. Churchill Livingstone, Edinburgh, pp. 1128-1139.
    • (1991) Textbook of Neurology , pp. 1128-1139
    • Link, H.1
  • 18
    • 0028641607 scopus 로고
    • Interferon-γ, interleukin-4 and transforming growth factor-ß mRNA expression in multiple sclerosis and myasthenia gravis
    • Link, J. (1994) Interferon-γ, interleukin-4 and transforming growth factor-ß mRNA expression in multiple sclerosis and myasthenia gravis. Acta Neurol. Scand. 90 (Suppl.), S1-S58.
    • (1994) Acta Neurol. Scand. , vol.90 , Issue.SUPPL.
    • Link, J.1
  • 19
    • 0017574898 scopus 로고
    • Principles of albumin and IgG analyses in neurological disorders. II. Influence of serum concentration on CSF and evaluation of blood-brain barrier damage
    • Link, H. and Tibbling, G. (1977) Principles of albumin and IgG analyses in neurological disorders. II. Influence of serum concentration on CSF and evaluation of blood-brain barrier damage. Scand. J. Clin. Lab. Invest. 37, 391-396.
    • (1977) Scand. J. Clin. Lab. Invest. , vol.37 , pp. 391-396
    • Link, H.1    Tibbling, G.2
  • 21
    • 0028260294 scopus 로고
    • Organ-specific autoantigens induce IFN-γ and IL-4 mRNA expression in mononuclear cells in multiple sclerosis and myasthenia gravis
    • Link, J., Söderström, M., Ljungdahl, Å., Höjeberg, B., Olsson, T., Xu, Z., Fredrikson, S., Wang, Z.-Y. and Link, H. (1994b) Organ-specific autoantigens induce IFN-γ and IL-4 mRNA expression in mononuclear cells in multiple sclerosis and myasthenia gravis. Neurology 44, 728-734.
    • (1994) Neurology , vol.44 , pp. 728-734
    • Link, J.1    Söderström, M.2    Ljungdahl, Å.3    Höjeberg, B.4    Olsson, T.5    Xu, Z.6    Fredrikson, S.7    Wang, Z.-Y.8    Link, H.9
  • 22
    • 0027422997 scopus 로고
    • Interferon-γ and interleukin-4-secreting cells in multiple sclerosis
    • Lu, C.Z., Jensen, M.A. and Arnason, B.G.W. (1993) Interferon-γ and interleukin-4-secreting cells in multiple sclerosis. J. Neuroimmunol. 46, 123-128.
    • (1993) J. Neuroimmunol. , vol.46 , pp. 123-128
    • Lu, C.Z.1    Jensen, M.A.2    Arnason, B.G.W.3
  • 23
    • 0026066932 scopus 로고
    • Cytokine levels in the cerebrospinal fluid and serum of patients with multiple sclerosis
    • Maimone, D., Gregory, S., Arnason, B.G. and Reder, A.T. (1991) Cytokine levels in the cerebrospinal fluid and serum of patients with multiple sclerosis. J. Neuroimmunol. 32, 67-74.
    • (1991) J. Neuroimmunol. , vol.32 , pp. 67-74
    • Maimone, D.1    Gregory, S.2    Arnason, B.G.3    Reder, A.T.4
  • 24
    • 0027414597 scopus 로고
    • T-cell lymphokine-induced secretion of cytokines from patients with multiple sclerosis
    • Maimone, D., Reder, A.T. and Gregory, S. (1993) T-cell lymphokine-induced secretion of cytokines from patients with multiple sclerosis. Cell. Immunol. 146, 96-106.
    • (1993) Cell. Immunol. , vol.146 , pp. 96-106
    • Maimone, D.1    Reder, A.T.2    Gregory, S.3
  • 25
  • 26
    • 0023851809 scopus 로고
    • The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for terminal differentiation of B cells
    • Muraguchi, A., Hirano, T., Tang, B., Matsuda, T., Horii, Y., Nakajima, K. and Kishimoto, T. (1988) The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for terminal differentiation of B cells. J. Exp. Med. 167, 332-344.
    • (1988) J. Exp. Med. , vol.167 , pp. 332-344
    • Muraguchi, A.1    Hirano, T.2    Tang, B.3    Matsuda, T.4    Horii, Y.5    Nakajima, K.6    Kishimoto, T.7
  • 28
    • 27044442555 scopus 로고
    • Augmented expression of tumor necrosis factor-α and lymphotoxin mRNA in mononuclear cells in multiple sclerosis and optic neuritis
    • in press
    • Navikas, V., He, B., Link, J., Haglund, M., Söderström, M., Fredrikson, S., Höjeberg, B., Qiao, J., Olsson, T. and Link, H. (1995b) Augmented expression of tumor necrosis factor-α and lymphotoxin mRNA in mononuclear cells in multiple sclerosis and optic neuritis. Brain, in press.
    • (1995) Brain
    • Navikas, V.1    He, B.2    Link, J.3    Haglund, M.4    Söderström, M.5    Fredrikson, S.6    Höjeberg, B.7    Qiao, J.8    Olsson, T.9    Link, H.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.