Site-specific production of IL-6 in the central nervous system retargets and enhances the inflammatory response in experimental autoimmune encephalomyelitis

Journal of Immunology

Volumn 183, Issue 3, 2009, Pages 2079-2088

  Quintana, Albert ^a,b,c   Müller, Marcus ^a,d   Frausto, Ricardo F ^a   Ramos, Raquel ^b   Getts, Daniel R ^a,e   Sanz, Elisenda ^a,b,c   Hofer, Markus J ^a,f   Krauthausen, Marius ^a,c   King, Nicholas J C ^a   Hidalgo, Juan ^b   Campbell, Iain L ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF BARCELONA   (Spain)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF BONN   (Germany)

^e NORTHWESTERN UNIVERSITY   (United States)

^f PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 6; MESSENGER RNA; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; MYELIN ASSOCIATED GLYCOPROTEIN; OLIGODENDROCYTE MYELIN GLYCOPROTEIN; OLIGODENDROCYTE-MYELIN GLYCOPROTEIN;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATAXIA; B LYMPHOCYTE; BLOOD BRAIN BARRIER; CELL ACTIVATION; CELL COUNT; CELL INFILTRATION; CENTRAL NERVOUS SYSTEM; CEREBELLUM; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; FEMALE; INFLAMMATION; INFLAMMATORY CELL; LEUKOCYTE; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PARALYSIS; PRIORITY JOURNAL; SPINAL CORD; TISSUE INJURY; TRANSGENIC MOUSE; WILD TYPE; ANIMAL; AUTOIMMUNITY; BIOSYNTHESIS; CHEMICALLY INDUCED DISORDER; CHEMOTAXIS; IMMUNOLOGY; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY;

ANIMALS; AUTOIMMUNITY; CENTRAL NERVOUS SYSTEM; CEREBELLUM; CHEMOTAXIS; CYTOKINES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; INFLAMMATION; INTERLEUKIN-6; MICE; MICE, TRANSGENIC; MYELIN-ASSOCIATED GLYCOPROTEIN; PARALYSIS;

EID: 68149148572     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0900242     Document Type: Article

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