Production and functions of IL-17 in microglia

Journal of Neuroimmunology

Volumn 194, Issue 1-2, 2008, Pages 54-61

  Kawanokuchi, Jun ^a   Shimizu, Kouki ^a   Nitta, Atsumi ^b   Yamada, Kiyofumi ^b   Mizuno, Tetsuya ^a   Takeuchi, Hideyuki ^a   Suzumura, Akio ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Cytokine; EAE; IL 17; Microglia; MS

Indexed keywords

CYTOKINE; INTERLEUKIN 17; INTERLEUKIN 17 RECEPTOR; INTERLEUKIN 1BETA; INTERLEUKIN 23; MESSENGER RNA; NITRIC OXIDE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; AUTOCRINE EFFECT; BRAIN NERVE CELL; CONTROLLED STUDY; HELPER CELL; MICROGLIA; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR UPREGULATION;

ANIMALS; AUTOCRINE COMMUNICATION; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELLS, CULTURED; CHEMOKINE CXCL2; GENE EXPRESSION REGULATION; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; HUMANS; INTERLEUKIN-17; INTERLEUKIN-1BETA; INTERLEUKIN-23; INTERLEUKIN-6; MICE; MICROGLIA; MULTIPLE SCLEROSIS; NITRIC OXIDE; RECEPTORS, INTERLEUKIN-17; RECOMBINANT PROTEINS; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 39849092553     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2007.11.006     Document Type: Article

References (42)

1. Aggarwal S., and Gurney A.L. IL-17: prototype member of an emerging cytokine family. J. Leukoc. Biol. 71 (2002) 1-8
2. Aggarwal S., Ghilardi N., Xie M.H., de Sauvage F.J., and Gurney A.L. Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J. Biol. Chem. 278 3 (2003) 1910-1914
3. Batten M., Li J., Yi S., Kljavin N.M., Danilenko D.M., Lucas S., Lee J., de Sauvage F.J., and Ghilardi N. Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells. Nat. Immunol. 7 (2006) 929-936
4. Bessis A., Bechade C., Bernard D., and Roumier A. Microglial control of neuronal death and synaptic properties. Glia 55 3 (2007) 233-238 Review
5. Bettelli E., Carrier Y., Gao W., Korn T., Strom T.B., Oukka M., Weiner H.L., and Kuchroo V.K. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 441 7090 (2006) 235-238
6. Cai X.Y., Gommoll Jr. C.P., Justice L., Narula S.K., and Fine J.S. Regulation of granulocyte colony-stimulating factor gene expression by interleukin-17. Immunol. Lett. 62 (1998) 51-58
7. Chabaud M., Fossiez F., Taupin J.L., and Miossec P. Enhancing effect of IL-17 on IL-1-induced IL-6 and leukemia inhibitory factor production by rheumatoid arthritis synoviocytes and its regulation by Th2 cytokines. J. Immunol. 161 (1998) 409-414
8. Chen Y., Langrish C.L., McKenzie B., Joyce-Shaikh B., Stumhofer J.S., McClanahan T., Blumenschein W., Churakovsa T., Low J., Presta L., Hunter C.A., Kastelein R.A., and Cua D.J. Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis. J. Clin. Invest. 116 5 (2006) 1317-1326
9. Fossiez F., Djossou O., Chomarat P., Flores-Romo L., Ait-Yahia S., Maat C., Pin J.J., Garrone P., Garcia E., Saeland S., Blanchard D., Gaillard C., Das M.B., Rouvier E., Golstein P., Banchereau J., and Lebecque S. T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines. J. Exp. Med. 183 (1996) 2593-2603
10. Furukawa S., Kamo I., Furukawa Y., Akazawa S., Satoyoshi E., Itoh K., and Hayashi K. A highly sensitive enzyme immunoassay for mouse beta nerve growth factor. J. Neurochem. 40 (1983) 734-744
11. + effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat. Immunol. 6 11 (2005) 1123-1132
12. Hofstetter H.H., Ibrahim S.M., Koczan D., Kruse N., Weishaupt A., Toyka K.V., and Gold R. Therapeutic efficacy of IL-17 neutralization in murine experimental autoimmune encephalomyelitis. Cell Immunol. 237 2 (2005) 123-130
13. Ignarro L.J., Buga G.M., Wood K.S., Byrns R.E., and Chaudhuri G. Endothelium-derived relaxing factor produced and released from artery and vein in nitric oxide. Proc. Natl. Acad. Sci. USA, 84 (1987) 9265-9269
14. Ishizu T., Osoegawa M., Mei F.J., Kikuchi H., Tanaka M., Takakura Y., Minohara M., Murai H., Mihara F., Taniwaki T., and Kira J. Intrathecal activation of the IL-17/IL-8 axis in opticospinal multiple sclerosis. Brain 128 (2005) 988-1002
15. + T helper cells. Cell 126 (2006) 1121-1133
16. Iwakura Y., and Ishigame H. The IL-23/IL-17 axis in inflammation. J. Clin. Invest. 116 5 (2006) 1218-1922
17. Jovanovic D.V., Di B.J.A., Martel-Pelletier J., Jolicoeur F.C., He Y., Zhang M., Mineau F., and Pelletier J.P. IL-17 stimulates the production and expression of proinflammatory cytokines, IL-b and TNFa, by human macrophages. J. Immunol. 160 (1998) 3513-3521
18. Kaechi K., Furukawa Y., Ikegami R., Nakamura N., Omae F., Hashimoto Y., Hayashi K., and Furukawa S. Pharmacological induction of physiologically active nerve growth factor in rat peripheral nervous system. J. Pharmacol. Exp. Ther. 264 (1993) 321-326
19. -T cells. J. Interferon Cytokine Res. 16 (1996) 611-617
20. Komiyama Y., Nakae S., Matsuki T., Nambu A., Ishigame H., Kakuta S., Sudo K., and Iwakura Y. IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis. J. Immunol. 177 (2006) 566-573
21. Kuno R., Yoshida Y., Nitta A., Nabeshima T., Wang J., Sonobe Y., Kawanokuchi J., Takeuchi H., Mizuno T., and Suzumura A. The role of TNF-alpha and its receptors in the production of NGF and GDNF by astrocytes. Brain Res. 1116 1 (2006) 12-18
22. Laan M., Cui Z.H., Hoshino H., Lotvall J., Sjostrand M., Gruenert D.C., Skoogh B.E., and Linden A. Neutrophil recruitment by human IL-17 via C-X-C chemokine release in the airways. J. Immunol. 162 (1999) 2347-2352
23. Laemmli U.K., and Favre M. Maturation of the head of bacteriophage T4. I. DNA packaging events. J. Mol. Biol. 80 4 (1973) 575-579
24. Li G.Z., Zhong D., Yang L.M., Sun B., Zhong Z.H., Yin Y.H., Cheng J., Yan B.B., and Li H.L. Expression of interleukin-17 in ischemic brain tissue. Scand. J. Immunol. 62 5 (2005) 481-486
25. Li Y., Chu N., Hu A., Gran B., Rostami A., and Zhang G.X. Increased IL-23p19 expression in multiple sclerosis lesions and its induction in microglia. Brain 130 Pt2 (2007) 490-501
26. Linden A., Hoshino H., and Laan M. Airway neutrophils and interleukin-17. Eur. Respir. J. 15 (2000) 973-977
27. Lock C., Hermans G., Pedotti R., Brendolan A., Schadt E., Garren H., Langer-Gould A., Strober S., Cannella B., Allard J., Klonowski P., Austin A., Lad N., Kaminski N., Galli S.J., Oksenberg J.R., Raine C.S., Heller R., and Steinman L. Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis. Nat. Med. 8 5 (2003) 500-208
28. Matusevicius D., Kivisakk P., He B., Kostulas N., Ozenci V., Fredrikson S., and Link H. Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis. Mult. Scler. 5 2 (1999) 101-104
29. Meeuwsen S., Persoon-Deen C., Bsibsi M., Ravid R., and van Noort J.M. Cytokine, chemokine and growth factor gene profiling of cultured human astrocytes after exposure to proinflammatory stimuli. Glia 43 3 (2003) 243-253
30. Nitta A., Ito M., Fukumitsu H., Ohmiya M., Ito H., Sometani A., Nomoto H., Furukawa Y., and Furukawa S. 4-methylcatechol increases brain-derived neurotrophic factor content and mRNA expression in cultured brain cells and in rat brain in vivo. J. Pharmacol. Exp. Ther. 291 (1999) 1276-1283
31. Nitta A., Nishioka H., Fukumitsu H., Furukawa Y., Sugiura H., Shen L., and Furukawa S. Hydrophobic dipeptide Leu-Ile protects against neuronal death by inducing brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor synthesis. J. Neurosci. Res. 78 (2004) 250-258
32. Park H., Li Z., Yang X.O., Chang S.H., Nurieva R., Wang Y.H., Wang Y., Hood L., Zhu Z., Tian Q., and Dong C. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat. Immunol. 6 11 (2005) 1133-1141
33. Pollock J.S., Forstermann U., Mitchell J.A., Warner T.D., Schmidt H.H.H.W., Nakane M., and Murad F. Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells. Proc. Natl. Acad. Sci. 88 (1991) 10480-10484
34. Röhn T.A., Jennings G.T., Hernandez M., Grest P., Beck M., Zou Y., Kopf M., and Bachmann M.F. Vaccination against IL-17 suppresses autoimmune arthritis and encephalomyelitis. Eur. J. Immunol. 36 11 (2006) 2844-2848
35. Sonobe Y., Yawata I., Kawanokuchi J., Takeuchi H., Mizuno T., and Suzumura A. Production of IL-27 and other IL-12 family cytokines by microglia and their subpopulations. Brain Res. 1040 1-2 (2005) 202-207
36. Suzumura A., Mezitis S.G., Gonatas N.K., and Silberberg D.H. MHC antigen expression on bulk isolated macrophage-microglia from newborn mouse brain: induction of Ia antigen expression by gamma-interferon. J. Neuroimmunol. 15 3 (1987) 263-278
37. Suzumura A., Takeuchi H., Zhang G., Kuno R., and Mizuno T. Roles of glia-derived cytokines on neuronal degeneration and regeneration. Ann. N. Y. Acad. Sci. 1088 (2006) 219-229 Review
38. Takeuchi H., Mizuno T., Zhang G., Wang J., Kawanokuchi J., Kuno R., and Suzumura A. Neuritic beading induced by activated microglia is an early feature of neuronal dysfunction toward neuronal death by inhibition of mitochondrial respiration and axonal transport. J. Biol. Chem. 280 11 (2005) 10444-10454
39. Towbin H., Staehelin T., and Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. U. S. A. 76 9 (1979) 4350-4354
40. Trajkovic V., Stosic-Grujicic S., Samardzic T., Markovic M., Miljkovic D., Ramic Z., and MostraricaStojkovic M. Interleukin-17 stimulates inducible nitric oxide synthase activation in rodent astrocytes. J. Neuroimmunol. 119 (2001) 183-191
41. Valdhoen M., Hocking R.J., Atkins C.J., Locksley R.M., and Stockinger B. TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17 producing T cells. Immunity 24 (2006) 179-189
42. Yao Z., Painter S.L., Fanslow W.C., Ulrich D., Macduff B.M., Spriggs M.K., and Armitage R.J. Human IL-17: a novel cytokine derived from T cells. J. Immunol. 155 12 (1995) 5483-5486