-
1
-
-
0034597789
-
Interleukin-21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function
-
Parrish-Novak J, Dillon SR, Nelson A et al. Interleukin-21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature 2000 408:57 63.
-
(2000)
Nature
, vol.408
, pp. 57-63
-
-
Parrish-Novak, J.1
Dillon, S.R.2
Nelson, A.3
-
2
-
-
0034633734
-
Cloning of a type I cytokine receptor most related to the IL-2 receptor beta chain
-
Ozaki K, Kikly K, Michalovich D, Young PR, Leonard WJ. Cloning of a type I cytokine receptor most related to the IL-2 receptor beta chain. Proc Natl Acad Sci USA 2000 97:11439 44.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 11439-44
-
-
Ozaki, K.1
Kikly, K.2
Michalovich, D.3
Young, P.R.4
Leonard, W.J.5
-
3
-
-
25444434157
-
Interleukin-21: A modulator of lymphoid proliferation, apoptosis and differentiation
-
Leonard WJ, Spolski R. Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation. Nat Rev Immunol 2005 5:688 98.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 688-98
-
-
Leonard, W.J.1
Spolski, R.2
-
4
-
-
2542565699
-
Interleukin-21 is a T-helper cytokine that regulates humoral immunity and cell-mediated anti-tumour responses
-
Sivakumar PV, Foster DC, Clegg CH. Interleukin-21 is a T-helper cytokine that regulates humoral immunity and cell-mediated anti-tumour responses. Immunology 2004 112:177 82.
-
(2004)
Immunology
, vol.112
, pp. 177-82
-
-
Sivakumar, P.V.1
Foster, D.C.2
Clegg, C.H.3
-
5
-
-
33750460981
-
IgE isotype switch and IgE production are enhanced in IL-21-deficient but not IFN-gamma-deficient mice in a Th2-biased response
-
Shang XZ, Ma KY, Radewonuk J et al. IgE isotype switch and IgE production are enhanced in IL-21-deficient but not IFN-gamma-deficient mice in a Th2-biased response. Cell Immunol 2006 241:66 74.
-
(2006)
Cell Immunol
, vol.241
, pp. 66-74
-
-
Shang, X.Z.1
Ma, K.Y.2
Radewonuk, J.3
-
6
-
-
33645983210
-
Autoreactive T cells mediate NK cell degeneration in autoimmune disease
-
Liu R, Van Kaer L, La Cava A et al. Autoreactive T cells mediate NK cell degeneration in autoimmune disease. J Immunol 2006 176:5247 54.
-
(2006)
J Immunol
, vol.176
, pp. 5247-54
-
-
Liu, R.1
Van Kaer, L.2
La Cava, A.3
-
7
-
-
14044262247
-
Differential effects of IL-21 during initiation and progression of autoimmunity against neuroantigen
-
Vollmer TL, Liu R, Price M, Rhodes S, La Cava A, Shi F-D. Differential effects of IL-21 during initiation and progression of autoimmunity against neuroantigen. J Immunol 2005 174:2696 701.
-
(2005)
J Immunol
, vol.174
, pp. 2696-701
-
-
Vollmer, T.L.1
Liu, R.2
Price, M.3
Rhodes, S.4
La Cava, A.5
Shi, F.-D.6
-
8
-
-
33745840137
-
The IL-21 receptor augments Th2 effector function and alternative macrophage activation
-
Pesce J, Kaviratne M, Ramalingam TR et al. The IL-21 receptor augments Th2 effector function and alternative macrophage activation. J Clin Invest 2006 116:2044 55.
-
(2006)
J Clin Invest
, vol.116
, pp. 2044-55
-
-
Pesce, J.1
Kaviratne, M.2
Ramalingam, T.R.3
-
9
-
-
0034028817
-
Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion
-
Jung S, Aliberti J, Graemmel P et al. Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol Cell Biol 2000 20:4106 14.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 4106-14
-
-
Jung, S.1
Aliberti, J.2
Graemmel, P.3
-
10
-
-
2642698865
-
Challenging cytokine redundancy: Inflammatory cell movement and clinical course of experimental autoimmune encephalomyelitis are normal in lymphotoxin-deficient, but not tumor necrosis factor-deficient, mice
-
Sean Riminton D, Körner H, Strickland DH, Lemckert FA, Pollard JD, Sedgwick JD. Challenging cytokine redundancy: inflammatory cell movement and clinical course of experimental autoimmune encephalomyelitis are normal in lymphotoxin-deficient, but not tumor necrosis factor-deficient, mice. J Exp Med 1998 187:1517 28.
-
(1998)
J Exp Med
, vol.187
, pp. 1517-28
-
-
Sean Riminton, D.1
Körner, H.2
Strickland, D.H.3
Lemckert, F.A.4
Pollard, J.D.5
Sedgwick, J.D.6
-
11
-
-
0034975741
-
Two-step activation of T cells, clonal expansion and subsequent Th1 cytokine production, is essential for the development of clinical autoimmune encephalomyelitis
-
Jee Y, Matsumoto Y. Two-step activation of T cells, clonal expansion and subsequent Th1 cytokine production, is essential for the development of clinical autoimmune encephalomyelitis. Eur J Immunol 2001 31:1800 12.
-
(2001)
Eur J Immunol
, vol.31
, pp. 1800-12
-
-
Jee, Y.1
Matsumoto, Y.2
-
12
-
-
4344691447
-
CD24 controls expansion and persistence of autoreactive T cells in the central nervous system during experimental autoimmune encephalomyelitis
-
Bai XF, Li O, Zhou Q et al. CD24 controls expansion and persistence of autoreactive T cells in the central nervous system during experimental autoimmune encephalomyelitis. J Exp Med 2004 200:447 58.
-
(2004)
J Exp Med
, vol.200
, pp. 447-58
-
-
Bai, X.F.1
Li, O.2
Zhou, Q.3
-
13
-
-
0024504033
-
Identification of an encephalitogenic determinant of myelin proteolipid protein for SJL mice
-
Tuohy VK, Lu Z, Sobel RA, Laursen RA, Lees MB. Identification of an encephalitogenic determinant of myelin proteolipid protein for SJL mice. J Immunol 1989 142:1523 27.
-
(1989)
J Immunol
, vol.142
, pp. 1523-27
-
-
Tuohy, V.K.1
Lu, Z.2
Sobel, R.A.3
Laursen, R.A.4
Lees, M.B.5
-
14
-
-
33846558558
-
Kinetics and organ distribution of IL-17-producing CD4 cells in proteolipid protein 139-151 peptide-induced experimental autoimmune encephalomyelitis of SJL mice
-
Hofstetter HH, Toyka KV, Tary-Lehmann M, Lehmann PV. Kinetics and organ distribution of IL-17-producing CD4 cells in proteolipid protein 139-151 peptide-induced experimental autoimmune encephalomyelitis of SJL mice. J Immunol 2007 178:1372 8.
-
(2007)
J Immunol
, vol.178
, pp. 1372-8
-
-
Hofstetter, H.H.1
Toyka, K.V.2
Tary-Lehmann, M.3
Lehmann, P.V.4
-
15
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
Bettelli E, Carrier Y, Gao W et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006 441:235 8.
-
(2006)
Nature
, vol.441
, pp. 235-8
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
-
17
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003 299:1057 61.
-
(2003)
Science
, vol.299
, pp. 1057-61
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
18
-
-
6344269331
-
Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6
-
Ozaki K, Spolski R, Ettinger R et al. Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6. J Immunol 2004 173:5361 71.
-
(2004)
J Immunol
, vol.173
, pp. 5361-71
-
-
Ozaki, K.1
Spolski, R.2
Ettinger, R.3
-
19
-
-
1942453326
-
Homeostatic expansion of T cells during immune insufficiency generates autoimmunity
-
King C, Ilic A, Koelsch K, Sarvetnick N. Homeostatic expansion of T cells during immune insufficiency generates autoimmunity. Cell 2004 117:265 77.
-
(2004)
Cell
, vol.117
, pp. 265-77
-
-
King, C.1
Ilic, A.2
Koelsch, K.3
Sarvetnick, N.4
-
20
-
-
0030029655
-
Immunogenic and encephalitogenic epitope clusters of myelin proteolipid protein
-
Greer JM, Sobel RA, Sette A, Southwood S, Lees MB, Kuchroo VK. Immunogenic and encephalitogenic epitope clusters of myelin proteolipid protein. J Immunol 1996 156:371 9.
-
(1996)
J Immunol
, vol.156
, pp. 371-9
-
-
Greer, J.M.1
Sobel, R.A.2
Sette, A.3
Southwood, S.4
Lees, M.B.5
Kuchroo, V.K.6
-
21
-
-
4544241811
-
Tolerance, not immunity, crucially depends on IL-2
-
Malek TR, Bayer AL. Tolerance, not immunity, crucially depends on IL-2. Nat Rev Immunol 2004 4:665 74.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 665-74
-
-
Malek, T.R.1
Bayer, A.L.2
-
23
-
-
34247257447
-
Blockade of the interleukin-21/interleukin-21 receptor pathway ameliorates disease in animal models of rheumatoid arthritis
-
Young DA, Hegen M, Ma HL et al. Blockade of the interleukin-21/ interleukin-21 receptor pathway ameliorates disease in animal models of rheumatoid arthritis. Arthritis Rheum 2007 56:1152 63.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 1152-63
-
-
Young, D.A.1
Hegen, M.2
Ma, H.L.3
-
24
-
-
33947215987
-
IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R.Fc reduces disease progression
-
Herber D, Brown TP, Liang S, Young DA, Collins M, Dunussi-Joannopoulos K. IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R.Fc reduces disease progression. J Immunol 2007 178:3822 30.
-
(2007)
J Immunol
, vol.178
, pp. 3822-30
-
-
Herber, D.1
Brown, T.P.2
Liang, S.3
Young, D.A.4
Collins, M.5
Dunussi-Joannopoulos, K.6
-
26
-
-
34547188748
-
IL-6 programs T (H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
-
Zhou L, IvanovII, Spolski R et al. IL-6 programs T (H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat Immunol 2007 8:967 74.
-
(2007)
Nat Immunol
, vol.8
, pp. 967-74
-
-
Zhou, L.1
Ivanov, I.I.2
Spolski, R.3
-
27
-
-
34547232503
-
IL-21 initiates an alternative pathway to induce proinflammatory T (H)-17 cells
-
Korn T, Bettelli E, Gao W et al. IL-21 initiates an alternative pathway to induce proinflammatory T (H)-17 cells. Nature 2007 448:484 7.
-
(2007)
Nature
, vol.448
, pp. 484-7
-
-
Korn, T.1
Bettelli, E.2
Gao, W.3
|