A role for platelets and endothelial selectins in tumor necrosis factor-α-induced leukocyte recruitment in the brain microvasculature

Circulation Research

Volumn 87, Issue 12, 2000, Pages 1141-1148

  Carvalho Tavares, Juliana ^a   Hickey, Michael J ^a   Hutchison, Jamie ^b   Michaud, Jean ^b   Sutcliffe, Ian T ^b   Kubes, Paul ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Cerebral; Inflammation; Neutrophil; Selectin; Tumor necrosis factor

Indexed keywords

ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; PADGEM PROTEIN; SELECTIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL TISSUE; ARTICLE; BRAIN MICROCIRCULATION; CELL INFILTRATION; CONTROLLED STUDY; ENDOTHELIUM CELL; INFLAMMATION; LEUKOCYTE ADHERENCE; MICROSCOPY; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; THROMBOCYTE;

EID: 0034623813     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.87.12.1141     Document Type: Article

References (46)

1. Staite ND Acceleration and increased severity of collagen-induced arthritis in P-selectin mutant mice
2. The adhesion molecule and cytokine profile of multiple sclerosis lesions
3. Mice deficient in Mac-1 (CD11b/CD18) are less susceptible to cerebral ischemia/reperfusion injury
4. Sequential contribution of L- and P-selectin to leukocyte rolling in vivo
5. Leukocyte rolling and extravasation are severely compromised in P-selectin-deficient mice
6. C5a-induced expression of P-selectin in endothelial cells
7. Rapid neutrophil adhesion to activated endothelium mediated by GMP-140
8. P-selectin mediates neutrophil rolling on histamine-stimulated endothelial cells
9. Histamine induces leukocyte rolling in post-capillary venules a P-selectin-mediated event
10. E-selectin supports neutrophil rolling in vitro under conditions of flow
11. Identification of an inducible endothelial-leukocyte adhesion molecule
12. Endogenous interleukin-10 regulates hemodynamic parameters, leukocyte-endothelial cell interactions, and microvascular permeability during endotoxemia
13. Mice lacking two or all three selectins demonstrate overlapping and distinct functions for each selectin
14. Characterization of E-selectin-deficient mice demonstration of overlapping function of the endothelial selectins
15. Reperfusion-induced leukocyte adhesion and vascular protein leakage in normal and hypercholesterolemic rats
16. P-selectin mediates the interaction of circulating leukocytes with platelets and microvascular endothelium in response to oxidized lipoprotein in vivo
17. Platelet-endothelial cell interactions during ischemia/reperfusion the role of P-selectin
18. Selectin-mediated rolling of neutrophils on immobilized platelets
19. 2-integrin CD11b/CD18
20. Intracerebral injection of proinflammatory cytokines or leukocyte chemotaxins induces minimal myelomonocytic cell recruitment to the parenchyma of the central nervous system
21. E- and P-selectin are not involved in the recruitment of inflammatory cells across the blood-brain barrier in experimental autoimmune encephalomyelitis
22. Intercellular adhesion molecule-1 (ICAM-1) in cellular immune reactions in the human central nervous system
23. Infectious susceptibility and severe deficiency of leukocyte rolling and recruitment in E-selectin and P-selectin double mutant mice
24. P-selectin/ICAM-1 double mutant mice acute emigration of neutrophils into the peritoneum is completely absent but is normal into pulmonary alveoli
25. 1) receptor antagonist inhibits leukocyte rolling in pial vessels in the early phase of bacterial meningitis in rats
26. A mechanism for the major histocompatibility complex-linked resistance to autoimmunity
27. Heterogeneity of expression of E- and P-selectins in vivo
28. VCAM-1 and ICAM-1 mediate leukocyte-endothelial cell adhesion in rat experimental colitis
29. 4-integrin, P-selectin, and E-selectin in an allergic model of inflammation
30. Assessment of the mechanism of juxtacrine activation and adhesion of leukocytes in liver microcirculation
31. Influence of garlic compared to aspirin on induced photothrombosis in mouse pial microvessels, in vivo
32. Varying roles of E-selectin and P-selectin in different microvascular beds in response to antigen
33. A minimal role for selectins in the recruitment of leukocytes into the inflamed liver microvasculature
34. Cultured murine cerebral microvascular endothelial cells contain von Willebrand factor-positive Weibel-Palade bodies and support rapid cytokine-induced neutrophil adhesion
35. P-selectin blockade following fluid-percussion injury behavioral and immunochemical sequelae
36. Anti-P-selectin antibody attenuates rat brain ischemic injury
37. Cytokine-induced meningitis is dramatically attenuated in mice deficient in endothelial selectins
38. The permeability of capillaries in various organs as determined by use of the 'indicator diffusion' method
39. Permeability of the microvascular barrier
40. Platelet-dependent primary hemostasis promotes sele
41. A juxtacrine mechanism for neutrophil adhesion on platelets involves platelet-activating factor and a selectin-dependent activation process
42. 3 integrin, and GPIbα
43. The glycoprotein Ib-IX-V complex is a platelet counterreceptor for P-selectin
44. Pathophysiology of cardiopulmonary bypass current issues
45. Aspirin, platelets and prevention of vascular disease
46. Platelet activity and stroke severity