Squalene monooxygenase-A target for hypercholesterolemic therapy

Biological Chemistry

Volumn 392, Issue 12, 2011, Pages 1053-1075

  Belter, Agnieszka ^a,c   Skupinska, Miroslawa ^a,c   Giel Pietraszuk, Malgorzata ^a   Grabarkiewicz, Tomasz ^b   Rychlewski, Leszek ^c   Barciszewski, Jan ^a  

^a INSTITUTE OF BIOORGANIC CHEMISTRY   (Poland)

^b AdvaChemLab   (Poland)

^c BIOINFOBANK INSTITUTE   (Poland)

Author keywords

Cholesterol; Drug design; Epoxidation; Hypercholesterolemia

Indexed keywords

3 [(3,3' BITHIOPHEN 5 YL)METHOXY] N (6,6 DIMETHYL 2 HEPTEN 4 YNYL) N ETHYLBENZYLAMINE; ALLYLAMINE; ANTIFUNGAL AGENT; ANTILIPEMIC AGENT; BUTENAFINE; CHOLESTEROL; ENZYME INHIBITOR; EPIGALLOCATECHIN GALLATE; GARLIC EXTRACT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; HYPOCHOLESTEROLEMIC AGENT; NAFTIFINE; PLANT EXTRACT; SQUALENE DERIVATIVE; SQUALENE MONOOXYGENASE; SQUALENE MONOOXYGENASE INHIBITOR; TERBINAFINE; UNCLASSIFIED DRUG;

CHOLESTEROL SYNTHESIS; CLINICAL PRACTICE; COST EFFECTIVENESS ANALYSIS; EPOXIDATION; HUMAN; HYPERCHOLESTEROLEMIA; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVIEW; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTICHOLESTEREMIC AGENTS; ENZYME INHIBITORS; HUMANS; HYPERCHOLESTEROLEMIA; SQUALENE MONOOXYGENASE; STRUCTURE-ACTIVITY RELATIONSHIP;

EUKARYOTA; FUNGI; MAMMALIA; VERTEBRATA;

EID: 80755169620     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2011.195     Document Type: Review

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