Getting a handle on Huntington's disease: The case for cholesterol

Nature Medicine

Volumn 15, Issue 3, 2009, Pages 253-254

  Katsuno, Masahisa ^a,b   Adachi, Hiroaki ^a   Sobue, Gen ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

24S HYDROXYCHOLESTEROL; AMYLOID BETA PROTEIN; BIOLOGICAL MARKER; CHOLESTEROL; CHOLESTEROL DERIVATIVE; CYTOCHROME P450; FARNESYL DIPHOSPHATE; GERANYLGERANIOL; GERANYLGERANYL PYROPHOSPHATE; HUNTINGTIN; ISOPRENOID; POLYGLUTAMINE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; CELL CULTURE; CELL DEATH; CHOLESTEROL METABOLISM; CLINICAL STUDY; DEGENERATIVE DISEASE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; HUNTINGTON CHOREA; LIPID BRAIN LEVEL; LIPOGENESIS; NERVE DEGENERATION; NERVE FIBER TRANSPORT; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SHORT SURVEY; TRANSGENIC MOUSE;

CHOLESTEROL; HUMANS; HUNTINGTON DISEASE;

EID: 61949195032     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm0309-253     Document Type: Short Survey

References (12)

1. Huntington, G. Med Surg. Rep. 26, 317-321 (1872).
2. Leoni, V. et al. Brain 131, 2851-2859 (2008).
3. Butler, R. & Bates, G. Nat. Rev. Neurosci. 7, 784-796 (2006).
4. Katsuno, M. et al. Nat. Med. 9, 768-773 (2003).
5. Valenza, M. et al. J. Neurosci. 25, 9932-9939 (2005).
6. Valenza, M. et al. Hum. Mol. Genet. 16, 2187-2198 (2007).
7. Kotti, T.J. et al. Proc. Natl. Acad. Sci. USA 103, 3869-3874 (2006).
8. Shobab, L.A. et al. Lancet Neurol. 4, 841-852 (2005).
9. Michikawa, M., Gong, J.S., Fan, Q.W., Sawamura, N. & Yanagisawa, K. J. Neurosci. 21, 7226-7235 (2001).
10. Papassotiropoulos, A. et al. Arch. Neurol. 60, 29-35 (2003).
11. Dupuis, L. et al. Neurology 70, 1004-1009 (2008).
12. Andersson, S., Gustafsson, N., Warner, M. & Gustafsson, J.A. Proc. Natl. Acad. Sci. USA 102, 3857-3862 (2005).