A high-content RNAi-screening assay to identify modulators of cholesterol accumulation in niemann-pick type C cells

Assay and Drug Development Technologies

Volumn 8, Issue 3, 2010, Pages 295-319

  Arora, Shilpi ^a   Beaudry, Christian ^a   Bisanz, Kristen M ^a   Sima, Chao ^a   Kiefer, Jeffrey A ^a   Azorsa, David O ^a  

^a TRANSLATIONAL GENOMICS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; CHOLESTEROL ESTER; FILIPIN; LOW DENSITY LIPOPROTEIN RECEPTOR; SMALL INTERFERING RNA; 4,4-DIFLUORO-4-BORA-3A,4A-DIAZA-S-INDACENE; BORON DERIVATIVE; FLUORESCENT DYE;

ARTICLE; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; FIBROBLAST; FLUORESCENCE IMAGING; GENE; GENE IDENTIFICATION; GENE LIBRARY; GENE SILENCING; GENETIC SCREENING; GENETIC TRANSFECTION; GENOMICS; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; NIEMANN PICK DISEASE; RAB9A GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; STAINING; CELL LINE; COMPUTER PROGRAM; DRUG SCREENING; GENETICS; IMAGE PROCESSING; METABOLISM; PHYSIOLOGY; STATISTICAL ANALYSIS;

BORON COMPOUNDS; CELL LINE; CHOLESTEROL; CHOLESTEROL ESTERS; DATA INTERPRETATION, STATISTICAL; DRUG EVALUATION, PRECLINICAL; FIBROBLASTS; FLUORESCENT DYES; GENOMICS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; NIEMANN-PICK DISEASE, TYPE C; RNA INTERFERENCE; RNA, SMALL INTERFERING; SOFTWARE;

EID: 77954476138     PISSN: 1540658X     EISSN: None     Source Type: Journal    
DOI: 10.1089/adt.2009.0240     Document Type: Article

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