Squalene epoxidase as hypocholesterolemic drug target revisited

Progress in Lipid Research

Volumn 42, Issue 1, 2003, Pages 37-50

  Chugh, Anita ^a   Ray, Abhijit ^a   Gupta, Jung B ^a  

^a RANBAXY LABORATORIES LTD   (India)

Author keywords

HMG CoA Reductase Inhibitors; Hypocholesterolemic; Hypolipidemic; Squalene; Squalene epoxidase; Statins

Indexed keywords

2,3 OXIDOSQUALENE; 3 [(3,3' BITHIOPHEN 5 YL)METHOXY] N (6,6 DIMETHYL 2 HEPTEN 4 YNYL) N ETHYLBENZYLAMINE; ANTIFUNGAL AGENT; ATORVASTATIN; BENZYLAMINE DERIVATIVE; CHOLESTEROL; FARNESYL DIPHOSPHATE; FLUINDOSTATIN; FR 194738; GALLIC ACID DERIVATIVE; GALLOCATECHIN; GARLIC EXTRACT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; HYPOCHOLESTEROLEMIC AGENT; LANOSTEROL SYNTHASE; MEVINOLIN; OLIVE OIL; POLYPHENOL DERIVATIVE; PRAVASTATIN; SELENOCYSTEINE; SIMVASTATIN; SQUALENE; SQUALENE DERIVATIVE; SQUALENE EPOXIDASE INHIBITOR; SQUALENE MONOOXYGENASE; SQUALENE SYNTHASE; STEROL; TELLURIUM; UNCLASSIFIED DRUG; UNINDEXED DRUG;

BLOOD LEVEL; CATALYSIS; CHEMOPROPHYLAXIS; CHOLESTEROL SYNTHESIS; COMPETITIVE INHIBITION; DERMATITIS; DRUG ACTIVITY; DRUG BLOOD LEVEL; DRUG DESIGN; DRUG EFFICACY; DRUG POTENCY; DRUG SAFETY; DRUG SYNTHESIS; DRUG TARGETING; ENZYME INHIBITION; FIRST PASS EFFECT; HUMAN; MOLECULAR STABILITY; NEUROPATHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN TARGETING; REVIEW; SKIN CELL; STEROL SYNTHESIS; TEA;

ANTICHOLESTEREMIC AGENTS; DRUG DESIGN; ENZYME INHIBITORS; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; HYPERCHOLESTEROLEMIA; OXYGENASES; SQUALENE MONOOXYGENASE;

ANIMALIA; CANIS FAMILIARIS;

EID: 0037211467     PISSN: 01637827     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0163-7827(02)00029-2     Document Type: Review

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