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Volumn 3, Issue 11, 2011, Pages 1367-1384

The tumor microenvironment: Part 1

Author keywords

immune components; immune evasion; nonimmune components; tumor microenvironment; tumor progression

Indexed keywords

ADENOSINE; AMG 714; ARGINASE; CHEMOKINE RECEPTOR CXCR4; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; GELATINASE B; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 12; INTERLEUKIN 18 RECEPTOR ALPHA; INTERLEUKIN 2; INTERLEUKIN 21; INTERLEUKIN 23; INTERLEUKIN 27; INTERLEUKIN 4; MATRILYSIN; PROGRAMMED DEATH 1 LIGAND 1; PROSTAGLANDIN E2; PROTEIN P53; PROTEIN TYROSINE KINASE; STAT3 PROTEIN; TIE RECEPTOR; TOSYLARGININE METHYL ESTER; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN;

EID: 80755142757     PISSN: 1750743X     EISSN: 17507448     Source Type: Journal    
DOI: 10.2217/imt.11.111     Document Type: Review
Times cited : (24)

References (165)
  • 1
    • 0024708518 scopus 로고
    • The distribution of secondary growths in cancer of the breast 1889
    • Paget S. The distribution of secondary growths in cancer of the breast. 1889. Cancer Metastasis. Rev. 8(2), 98-101 (1989).
    • (1989) Cancer Metastasis. Rev. , vol.8 , Issue.2 , pp. 98-101
    • Paget, S.1
  • 2
    • 70350683363 scopus 로고    scopus 로고
    • The tumor microenvironment: The making of a paradigm
    • Witz IP. The tumor microenvironment: the making of a paradigm. Cancer Microenviron. 2(Suppl. 1), 9-17 (2009).
    • (2009) Cancer Microenviron. , vol.2 , Issue.1 , pp. 9-17
    • Witz, I.P.1
  • 3
    • 0034254445 scopus 로고    scopus 로고
    • The influence of the microenvironment on the malignant phenotype
    • DOI 10.1016/S1357-4310(00)01756-1, PII S1357431000017561
    • Park CC, Bissell MJ, Barcellos Hoff MH. The influence of the microenvironment on the malignant phenotype. Mol. Med. Today 6(8), 324-329 (2000). (Pubitemid 30619340)
    • (2000) Molecular Medicine Today , vol.6 , Issue.8 , pp. 324-329
    • Park, C.C.1    Bissell, M.J.2    Barcellos-Hoff, M.H.3
  • 4
    • 58149481287 scopus 로고    scopus 로고
    • Breast cancer by proxy: Can the microenvironment be both the cause and consequence
    • Ronnov Jessen L, Bissell MJ. Breast cancer by proxy: can the microenvironment be both the cause and consequence? Trends Mol. Med. 15(1), 5-13 (2009).
    • (2009) Trends Mol. Med. , vol.15 , Issue.1 , pp. 5-13
    • Ronnov Jessen, L.1    Bissell, M.J.2
  • 6
    • 0347123433 scopus 로고    scopus 로고
    • Tumour-educated macrophages promote tumour progression and metastasis
    • Pollard JW. Tumour-educated macrophages promote tumour progression and metastasis. Nat. Rev. Cancer 4(1), 71-78 (2004). (Pubitemid 38082155)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.1 , pp. 71-78
    • Pollard, J.W.1
  • 8
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 100(1), 57-70 (2000). (Pubitemid 30046295)
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 9
    • 67650151005 scopus 로고    scopus 로고
    • Cancer-related inflammation the seventh hallmark of cancer: Links to genetic instability
    • Colotta F, Allavena P, Sica A, Garlanda C, Mantovani A. Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Carcinogenesis 30(7), 1073-1081 (2009).
    • (2009) Carcinogenesis , vol.30 , Issue.7 , pp. 1073-1081
    • Colotta, F.1    Allavena, P.2    Sica, A.3    Garlanda, C.4    Mantovani, A.5
  • 10
    • 77952568396 scopus 로고    scopus 로고
    • Hallmarks of cancer: Interactions with the tumor stroma
    • Pietras K, Ostman A. Hallmarks of cancer: interactions with the tumor stroma. Exp. Cell Res. 316(8), 1324-1331 (2010).
    • (2010) Exp. Cell Res. , vol.316 , Issue.8 , pp. 1324-1331
    • Pietras, K.1    Ostman, A.2
  • 15
    • 0029925375 scopus 로고    scopus 로고
    • Prognostic value of tumor infiltrating lymphocytes in the vertical growth phase of primary cutaneous melanoma
    • DOI 10.1002/(SICI)1097-0142(19960401)77:7<1303::AID-CNCR12>3.0. CO;2-5
    • Clemente CG, Mihm MC JR, Bufalino R, Zurrida S, Collini P, Cascinelli N. Prognostic value of tumor infiltrating lymphocytes in the vertical growth phase of primary cutaneous melanoma. Cancer 77(7), 1303-1310 (1996). (Pubitemid 26102328)
    • (1996) Cancer , vol.77 , Issue.7 , pp. 1303-1310
    • Clemente, C.G.1    Mihm Jr., M.C.2    Bufalino, R.3    Zurrida, S.4    Collini, P.5    Cascinelli, N.6
  • 16
    • 53549102755 scopus 로고    scopus 로고
    • The tumor microenvironment and its role in promoting tumor growth
    • Whiteside TL. The tumor microenvironment and its role in promoting tumor growth. Oncogene 27(45), 5904-5912 (2008).
    • (2008) Oncogene , vol.27 , Issue.45 , pp. 5904-5912
    • Whiteside, T.L.1
  • 17
    • 77649193013 scopus 로고    scopus 로고
    • Immune infiltration in human tumors: A prognostic factor that should not be ignored
    • Pages F, Galon J, Dieu-Nosjean MC et al. Immune infiltration in human tumors: a prognostic factor that should not be ignored. Oncogene 29 (8), 1093-1102 (2010).
    • (2010) Oncogene , vol.29 , Issue.8 , pp. 1093-1102
    • Pages, F.1    Galon, J.2    Dieu-Nosjean, M.C.3
  • 18
    • 79952093380 scopus 로고    scopus 로고
    • Histologic-based prognostic factors of colorectal cancers are associated with the state of local immune reaction
    • Mlecnik B, Tosolini M, Kirilovsky A et al. Histologic-based prognostic factors of colorectal cancers are associated with the state of local immune reaction. J. Clin. Oncol. 29 (6), 610-618 (2011).
    • (2011) J. Clin. Oncol. , vol.29 , Issue.6 , pp. 610-618
    • Mlecnik, B.1    Tosolini, M.2    Kirilovsky, A.3
  • 21
    • 0025050820 scopus 로고
    • Differentiation repertoire of fibroblastic cells: Expression of cytoskeletal proteins as marker of phenotypic modulations
    • Sappino AP, Schurch W, Gabbiani G. Differentiation repertoire of fibroblastic cells: expression of cytoskeletal proteins as marker of phenotypic modulations. Lab. Invest. 63(2), 144-161 (1990). (Pubitemid 20262130)
    • (1990) Laboratory Investigation , vol.63 , Issue.2 , pp. 144-161
    • Sappino, A.P.1    Schurch, W.2    Gabbiani, G.3
  • 22
    • 0033545334 scopus 로고    scopus 로고
    • Radial scars in benign breast-biopsy specimens and the risk of breast cancer
    • DOI 10.1056/NEJM199902113400604
    • Jacobs TW, Byrne C, Colditz G, Connolly JL, Schnitt SJ. Radial scars in benign breast-biopsy specimens and the risk of breast cancer. N. Engl. J. Med. 340(6), 430-436 (1999). (Pubitemid 29084774)
    • (1999) New England Journal of Medicine , vol.340 , Issue.6 , pp. 430-436
    • Jacobs, T.W.1    Byrne, C.2    Colditz, G.3    Connolly, J.L.4    Schnitt, S.J.5
  • 23
    • 5444261094 scopus 로고    scopus 로고
    • The stroma reaction myofibroblast: A key player in the control of tumor cell behavior
    • DOI 10.1387/ijdb.041802ad, Invasion in Cancer and Embryonic Development
    • Desmouliere A, Guyot C, Gabbiani G. The stroma reaction myofibroblast: a key player in the control of tumor cell behavior. Int. J. Dev. Biol. 48(5-6), 509-517 (2004). (Pubitemid 39360401)
    • (2004) International Journal of Developmental Biology , vol.48 , Issue.5-6 , pp. 509-517
    • Desmouliere, A.1    Guyot, C.2    Gabbiani, G.3
  • 24
    • 75849116069 scopus 로고    scopus 로고
    • Molecular biology of cancer-associated fibroblasts: Can these cells be targeted in anti-cancer therapy
    • Gonda TA, Varro A, Wang TC, Tycko B. Molecular biology of cancer-associated fibroblasts: can these cells be targeted in anti-cancer therapy? Semin. Cell Dev. Biol. 21(1), 2-10 (2010).
    • (2010) Semin. Cell Dev. Biol. , vol.21 , Issue.1 , pp. 2-10
    • Gonda, T.A.1    Varro, A.2    Wang, T.C.3    Tycko, B.4
  • 25
    • 60949101225 scopus 로고    scopus 로고
    • Cancer-associated fibroblasts and tumor growth - bystanders turning into key players
    • Ostman A, Augsten M. Cancer-associated fibroblasts and tumor growth - bystanders turning into key players. Curr. Opin Genet. Dev. 19(1), 67-73 (2009).
    • (2009) Curr. Opin. Genet. Dev. , vol.19 , Issue.1 , pp. 67-73
    • Ostman, A.1    Augsten, M.2
  • 26
    • 78149298209 scopus 로고    scopus 로고
    • Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein a
    • Kraman M, Bambrough PJ, Arnold JN et al. Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein a. Science 330 (6005), 827-830 (2010).
    • (2010) Science , vol.330 , Issue.6005 , pp. 827-830
    • Kraman, M.1    Bambrough, P.J.2    Arnold, J.N.3
  • 27
    • 33745837774 scopus 로고    scopus 로고
    • Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake
    • DOI 10.1172/JCI26532
    • Loeffler M, Kruger JA, Niethammer AG, Reisfeld RA. Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake. J. Clin. Invest. 116(7), 1955-1962 (2006). (Pubitemid 44033319)
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.7 , pp. 1955-1962
    • Loeffler, M.1    Kruger, J.A.2    Niethammer, A.G.3    Reisfeld, R.A.4
  • 28
    • 76349096670 scopus 로고    scopus 로고
    • Cancer-associated fibroblasts are activated in incipient neoplasia to orchestrate tumor-promoting inflammation in an NF kB-dependent manner
    • Erez N, Truitt M, Olson P, Arron ST, Hanahan D. Cancer-associated fibroblasts are activated in incipient neoplasia to orchestrate tumor-promoting inflammation in an NF kB-dependent manner. Cancer Cell 17(2),135-147 (2010).
    • (2010) Cancer Cell , vol.17 , Issue.2 , pp. 135-147
    • Erez, N.1    Truitt, M.2    Olson, P.3    Arron, S.T.4    Hanahan, D.5
  • 29
    • 25444506333 scopus 로고    scopus 로고
    • Stromal expression of connective tissue growth factor promotes angiogenesis and prostate cancer tumorigenesis
    • DOI 10.1158/0008-5472.CAN-05-1702
    • Yang F, Tuxhorn JA, Ressler SJ, McAlhany SJ, Dang TD, Rowley DR. Stromal expression of connective tissue growth factor promotes angiogenesis and prostate cancer tumorigenesis. Cancer Res. 65(19), 8887-8895 (2005). (Pubitemid 41377378)
    • (2005) Cancer Research , vol.65 , Issue.19 , pp. 8887-8895
    • Yang, F.1    Tuxhorn, J.A.2    Ressler, S.J.3    McAlhany, S.J.4    Dang, T.D.5    Rowley, D.R.6
  • 30
    • 18844428327 scopus 로고    scopus 로고
    • Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
    • DOI 10.1016/j.cell.2005.02.034, PII S0092867405002370
    • Orimo A, Gupta PB, Sgroi DC et al. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF 1/CXCL12 secretion. Cell 121(3), 335-348 (2005). (Pubitemid 40692295)
    • (2005) Cell , vol.121 , Issue.3 , pp. 335-348
    • Orimo, A.1    Gupta, P.B.2    Sgroi, D.C.3    Arenzana-Seisdedos, F.4    Delaunay, T.5    Naeem, R.6    Carey, V.J.7    Richardson, A.L.8    Weinberg, R.A.9
  • 31
    • 60949112215 scopus 로고    scopus 로고
    • CXCL14 is an autocrine growth factor for fibroblasts and acts as a multi-modal stimulator of prostate tumor growth
    • Augsten M, Hagglof C, Olsson E et al. CXCL14 is an autocrine growth factor for fibroblasts and acts as a multi-modal stimulator of prostate tumor growth. Proc. Natl Acad Sci. USA 106(9), 3414-3419 (2009).
    • (2009) Proc. Natl Acad Sci. USA , vol.106 , Issue.9 , pp. 3414-3419
    • Augsten, M.1    Hagglof, C.2    Olsson, E.3
  • 32
    • 58749093606 scopus 로고    scopus 로고
    • CCL3-CCR5 axis regulates intratumoral accumulation of leukocytes and fibroblasts and promotes angiogenesis in murine lung metastasis process
    • Wu Y, Li YY, Matsushima K, Baba T, Mukaida N. CCL3-CCR5 axis regulates intratumoral accumulation of leukocytes and fibroblasts and promotes angiogenesis in murine lung metastasis process. J. Immunol. 181(9), 6384-6393 (2008).
    • (2008) J. Immunol. , vol.181 , Issue.9 , pp. 6384-6393
    • Wu, Y.1    Li, Y.Y.2    Matsushima, K.3    Baba, T.4    Mukaida, N.5
  • 35
    • 0036843937 scopus 로고    scopus 로고
    • Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas
    • Kurose K, Gilley K, Matsumoto S, Watson PH, Zhou XP, Eng C. Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas. Nat. Genet. 32(3), 355-357 (2002).
    • (2002) Nat. Genet. , vol.32 , Issue.3 , pp. 355-357
    • Kurose, K.1    Gilley, K.2    Matsumoto, S.3    Watson, P.H.4    Zhou, X.P.5    Eng, C.6
  • 36
  • 37
    • 46349108651 scopus 로고    scopus 로고
    • Attenuated p53 activation in tumour-associated stromal cells accompanies decreased sensitivity to etoposide and vincristine
    • DOI 10.1038/sj.bjc.6604465, PII 6604465
    • Dudley AC, Shih SC, Cliffe AR, Hida K, Klagsbrun M. Attenuated p53 activation in tumour-associated stromal cells accompanies decreased sensitivity to etoposide and vincristine. Br. J. Cancer 99(1), 118-125 (2008). (Pubitemid 351920247)
    • (2008) British Journal of Cancer , vol.99 , Issue.1 , pp. 118-125
    • Dudley, A.C.1    Shih, S.-C.2    Cliffe, A.R.3    Hida, K.4    Klagsbrun, M.5
  • 39
    • 60149098323 scopus 로고    scopus 로고
    • Cancer cells suppress p53 in adjacent fibroblasts
    • Bar J, Feniger Barish R, Lukashchuk N et al. Cancer cells suppress p53 in adjacent fibroblasts. Oncogene 28(6), 933-936 (2009).
    • (2009) Oncogene , vol.28 , Issue.6 , pp. 933-936
    • Bar, J.1    Feniger Barish, R.2    Lukashchuk, N.3
  • 40
    • 17844379227 scopus 로고    scopus 로고
    • Identification of extracellular and intracellular signaling components of the mammary adipose tissue and its interstitial fluid in high risk breast cancer patients: Toward dissecting the molecular circuitry of epithelial-adipocyte stromal cell interactions
    • Celis JE, Moreira JM, Cabezon T et al. Identification of extracellular and intracellular signaling components of the mammary adipose tissue and its interstitial fluid in high risk breast cancer patients: toward dissecting the molecular circuitry of epithelial-adipocyte stromal cell interactions. Mol. Cell. Proteomics 4(4), 492-522 (2005).
    • (2005) Mol. Cell. Proteomics , vol.4 , Issue.4 , pp. 492-522
    • Celis, J.E.1    Moreira, J.M.2    Cabezon, T.3
  • 41
    • 67650561470 scopus 로고    scopus 로고
    • Obesity potentiates the growth and dissemination of pancreatic cancer
    • Zyromski NJ, Mathur A, Pitt HA et al. Obesity potentiates the growth and dissemination of pancreatic cancer. Surgery 146(2), 258-263 (2009).
    • (2009) Surgery , vol.146 , Issue.2 , pp. 258-263
    • Zyromski, N.J.1    Mathur, A.2    Pitt, H.A.3
  • 42
    • 70350231608 scopus 로고    scopus 로고
    • Adipocytes impair leukemia treatment in mice
    • Behan JW, Yun JP, Proektor MP et al. Adipocytes impair leukemia treatment in mice. Cancer Res. 69(19), 7867-7874 (2009).
    • (2009) Cancer Res. , vol.69 , Issue.19 , pp. 7867-7874
    • Behan, J.W.1    Yun, J.P.2    Proektor, M.P.3
  • 45
    • 49049121594 scopus 로고    scopus 로고
    • Mechanotransduction from the ECM to the genome: Are the pieces now in place
    • Gieni RS, Hendzel MJ. Mechanotransduction from the ECM to the genome: are the pieces now in place? J. Cell Biochem. 104(6), 1964-1987 (2008).
    • (2008) J. Cell Biochem. , vol.104 , Issue.6 , pp. 1964-1987
    • Gieni, R.S.1    Hendzel, M.J.2
  • 46
    • 21844445554 scopus 로고    scopus 로고
    • Extracellular matrix in bone marrow can mediate drug resistance in myeloma
    • DOI 10.1080/10428190500051448
    • Vincent T, Mechti N. Extracellular matrix in bone marrow can mediate drug resistance in myeloma. Leuk. Lymphoma. 46(6), 803-811 (2005). (Pubitemid 40959669)
    • (2005) Leukemia and Lymphoma , vol.46 , Issue.6 , pp. 803-811
    • Vincent, T.1    Mechti, N.2
  • 47
    • 0036204974 scopus 로고    scopus 로고
    • Extracellular matrix regulation of drug resistance in small-cell lung cancer
    • DOI 10.1042/CS20010216
    • Rintoul RC, Sethi T. Extracellular matrix regulation of drug resistance in small-cell lung cancer. Clin. Sci. (Lond.) 102(4), 417-424 (2002). (Pubitemid 34275794)
    • (2002) Clinical Science , vol.102 , Issue.4 , pp. 417-424
    • Rintoul, R.C.1    Sethi, T.2
  • 48
    • 72949119124 scopus 로고    scopus 로고
    • Integrins in cancer: Biological implications and therapeutic opportunities
    • Desgrosellier JS, Cheresh DA. Integrins in cancer: biological implications and therapeutic opportunities. Nat. Rev. Cancer. 10(1), 9-22 (2010).
    • (2010) Nat. Rev. Cancer. , vol.10 , Issue.1 , pp. 9-22
    • Desgrosellier, J.S.1    Cheresh, D.A.2
  • 49
    • 34250749644 scopus 로고    scopus 로고
    • Matrix metalloproteinase-induced malignancy in mammary epithelial cells
    • DOI 10.1159/000101310
    • Stallings-Mann M, Radisky D. Matrix metalloproteinase-induced malignancy in mammary epithelial cells. Cells Tissues Organs 185(1-3), 104-110 (2007). (Pubitemid 46956850)
    • (2007) Cells Tissues Organs , vol.185 , Issue.1-3 , pp. 104-110
    • Stallings-Mann, M.1    Radisky, D.2
  • 50
    • 0038476594 scopus 로고    scopus 로고
    • Genome-wide analysis of organ-preferential metastasis of human small cell lung cancer in mice
    • Kakiuchi S, Daigo Y, Tsunoda T, Yano S, Sone S, Nakamura Y. Genome-wide analysis of organ-preferential metastasis of human small cell lung cancer in mice. Mol. Cancer Res. 1(7), 485-499 (2003). (Pubitemid 36577045)
    • (2003) Molecular Cancer Research , vol.1 , Issue.7 , pp. 485-499
    • Kakiuchi, S.1    Daigo, Y.2    Tsunoda, T.3    Yano, S.4    Sone, S.5    Nakamura, Y.6
  • 51
    • 33644874747 scopus 로고    scopus 로고
    • Potential prognostic and therapeutic roles for cytokines in breast cancer review
    • Rao VS, Dyer CE, Jameel JK, Drew PJ, Greenman J. Potential prognostic and therapeutic roles for cytokines in breast cancer (review).Oncol. Rep. 15(1), 179-185 (2006).
    • (2006) Oncol. Rep. , vol.15 , Issue.1 , pp. 179-185
    • Rao, V.S.1    Dyer, C.E.2    Jameel, J.K.3    Drew, P.J.4    Greenman, J.5
  • 53
    • 78651276266 scopus 로고    scopus 로고
    • Proinflammatory cytokines in breast cancer: Mechanisms of action and potential targets for therapeutics
    • Goldberg JE, Schwertfeger KL. Proinflammatory cytokines in breast cancer: mechanisms of action and potential targets for therapeutics. Curr. Drug Targets 11(9), 1133-1146 (2010).
    • (2010) Curr. Drug Targets , vol.11 , Issue.9 , pp. 1133-1146
    • Goldberg, J.E.1    Schwertfeger, K.L.2
  • 54
    • 70450207740 scopus 로고    scopus 로고
    • Interferon g in brain tumor immunotherapy
    • Kane A, Yang I. Interferon g in brain tumor immunotherapy. Neurosurg. Clin. N. Am. 21(1), 77-86 (2010).
    • (2010) Neurosurg. Clin. N. Am. , vol.21 , Issue.1 , pp. 77-86
    • Kane, A.1    Yang, I.2
  • 57
    • 77949329326 scopus 로고    scopus 로고
    • Chemokines and chemokine receptors: New insights into cancer-related inflammation
    • Lazennec G, Richmond A. Chemokines and chemokine receptors: new insights into cancer-related inflammation. Trends Mol. Med. 16(3), 133-144 (2010).
    • (2010) Trends Mol. Med. , vol.16 , Issue.3 , pp. 133-144
    • Lazennec, G.1    Richmond, A.2
  • 58
    • 33751249635 scopus 로고    scopus 로고
    • The chemokine network: A target in cancer biology?
    • DOI 10.1016/j.addr.2006.03.012, PII S0169409X06001414
    • Slettenaar VI, Wilson JL. The chemokine network: a target in cancer biology? Adv. Drug Deliv. Rev. 58(8), 962-974 (2006). (Pubitemid 44780906)
    • (2006) Advanced Drug Delivery Reviews , vol.58 , Issue.8 , pp. 962-974
    • Slettenaar, V.I.F.1    Wilson, J.L.2
  • 59
    • 36148993318 scopus 로고    scopus 로고
    • Chemokines in tumor angiogenesis and metastasis
    • DOI 10.1007/s10555-007-9068-9, Forty Years of Metastasis Research: A Tribute to Dr. Isaiah J. Fidler
    • Sing S, Sadanandam A, Sing RK. Chemokines in tumor angiogenesis and metastasis. Cancer Metast. Rev. 26(3-4), 453-467 (2007). (Pubitemid 350115099)
    • (2007) Cancer and Metastasis Reviews , vol.26 , Issue.3-4 , pp. 453-467
    • Singh, S.1    Sadanandam, A.2    Singh, R.K.3
  • 60
    • 34548665711 scopus 로고    scopus 로고
    • Role of chemokines in tumor growth
    • DOI 10.1016/j.canlet.2007.05.013, PII S0304383507002509
    • Raman D, Baugher PJ Thu YM, Richmond A. Role of chemokines in tumor growth. Cancer Lett. 256 (2), 137-165 (2007). (Pubitemid 47418345)
    • (2007) Cancer Letters , vol.256 , Issue.2 , pp. 137-165
    • Raman, D.1    Baugher, P.J.2    Thu, Y.M.3    Richmond, A.4
  • 61
    • 44349100383 scopus 로고    scopus 로고
    • Organ selectivity in metastasis: Regulation by chemokines and their receptors
    • Ben-Baruch A. Organ selectivity in metastasis: regulation by chemokines and their receptors. Clin. Exp. Metast. 25 (4), 345-356 (2007).
    • (2007) Clin. Exp. Metast. , vol.25 , Issue.4 , pp. 345-356
    • Ben-Baruch, A.1
  • 62
    • 47749097074 scopus 로고    scopus 로고
    • The inflammatory chemokines CCL2 and CCL5 in breast cancer
    • Soria G, Ben Baruch A. The inflammatory chemokines CCL2 and CCL5 in breast cancer. Cancer Lett. 267(2), 271-285 (2008).
    • (2008) Cancer Lett. , vol.267 , Issue.2 , pp. 271-285
    • Soria, G.1    Ben Baruch, A.2
  • 63
    • 85011940682 scopus 로고    scopus 로고
    • Site-specific metastasis formation: Chemokines as regulators of tumor cell adhesion motility and invasion
    • Ben-Baruch A. Site-specific metastasis formation: chemokines as regulators of tumor cell adhesion, motility and invasion. Cell Adh. Migr. 3(4), 328-333 (2009).
    • (2009) Cell Adh. Migr. , vol.3 , Issue.4 , pp. 328-333
    • Ben-Baruch, A.1
  • 64
    • 78649637459 scopus 로고    scopus 로고
    • Chemokines at the crossroads of tumor-fibroblast interactions that promote malignancy
    • Mishra P, Banerjee D, Ben-Baruch A. Chemokines at the crossroads of tumor-fibroblast interactions that promote malignancy. J. Leukoc. Biol. 89(1), 31-39 (2011).
    • (2011) J. Leukoc. Biol. , vol.89 , Issue.1 , pp. 31-39
    • Mishra, P.1    Banerjee, D.2    Ben-Baruch, A.3
  • 65
    • 77951631347 scopus 로고    scopus 로고
    • Multiple roles of of chemokines C-C motif ligand 2 in promoting prostate cancer growth
    • Zhang J, Lu Y, Pienta K. Multiple roles of of chemokines (C-C motif ) ligand 2 in promoting prostate cancer growth. J. Natl Cancer Inst. 102(8), 522-528 (2010).
    • (2010) J. Natl Cancer Inst. , vol.102 , Issue.8 , pp. 522-528
    • Zhang, J.1    Lu, Y.2    Pienta, K.3
  • 66
    • 77950882020 scopus 로고    scopus 로고
    • The CXCR4/SDF chemokine axis: A potential therapeutic target for bone metastasis
    • Hirbe AC, Morgan EA, Welbaecher KN. The CXCR4/SDF chemokine axis: a potential therapeutic target for bone metastasis? Curr. Pharm. Des. 16(11), 1284-1290 (2010).
    • (2010) Curr. Pharm. Des. , vol.16 , Issue.11 , pp. 1284-1290
    • Hirbe, A.C.1    Morgan, E.A.2    Welbaecher, K.N.3
  • 67
    • 77549086214 scopus 로고    scopus 로고
    • CC chemokine ligand 2 CCL2 promotes prostate cancer tumorigenesis and metastasis
    • Zhang J, Patel L and Pienta KJ. CC chemokine ligand 2 (CCL2) promotes prostate cancer tumorigenesis and metastasis. Cytokine Growth Factor Rev. 21(1), 41-48 (2010).
    • (2010) Cytokine Growth Factor Rev. , vol.21 , Issue.1 , pp. 41-48
    • Zhang, J.1    Patel, L.2    Pienta, K.J.3
  • 68
    • 33746092947 scopus 로고    scopus 로고
    • Immune suppression in the tumor microenvironment
    • DOI 10.1097/01.cji.0000199193.29048.56, PII 0000237120060500000001
    • Gajewski TF, Meng Y, Harlin H. Immune suppression in the tumor microenvironment. J. Immunother. 29(3), 233-240 (2006). (Pubitemid 44297291)
    • (2006) Journal of Immunotherapy , vol.29 , Issue.3 , pp. 233-240
    • Gajewski, T.F.1    Meng, Y.2    Harlin, H.3
  • 70
    • 33646474329 scopus 로고    scopus 로고
    • Effector-phase tolerance: Another mechanism of how cancer escapes antitumor immune response
    • DOI 10.1189/jlb.1105628
    • Frey AB, Monu N. Effector-phase tolerance: another mechanism of how cancer escapes antitumor immune response. J. Leukoc. Biol. 79(4), 652-662 (2006). (Pubitemid 44835597)
    • (2006) Journal of Leukocyte Biology , vol.79 , Issue.4 , pp. 652-662
    • Frey, A.B.1    Monu, N.2
  • 71
    • 34347340406 scopus 로고    scopus 로고
    • Focus on TILs: Prognostic significance of tumor infiltrating lymphocytes in human bladder cancer
    • Liakou CI, Narayanan S, Ng Tang D, Logothetis CJ, Sharma P. Focus on TILs: prognostic significance of tumor infiltrating lymphocytes in human bladder cancer. Cancer Immun. 7, 10 (2007).
    • (2007) Cancer Immun. , vol.7 , pp. 10
    • Liakou, C.I.1    Narayanan, S.2    Ng Tang, D.3    Logothetis, C.J.4    Sharma, P.5
  • 72
    • 33947259319 scopus 로고    scopus 로고
    • Immunosuppressive strategies that are mediated by tumor cells
    • DOI 10.1146/annurev.immunol.25.022106.141609
    • Rabinovich GA, Gabrilovich D, Sotomayor EM. Immunosuppressive strategies that are mediated by tumor cells. Annu. Rev. Immunol. 25, 267-296 (2007). (Pubitemid 46697910)
    • (2007) Annual Review of Immunology , vol.25 , pp. 267-296
    • Rabinovich, G.A.1    Gabrilovich, D.2    Sotomayor, E.M.3
  • 73
    • 53549087527 scopus 로고    scopus 로고
    • How tumours escape mass destruction
    • Stewart TJ, Abrams SI. How tumours escape mass destruction. Oncogene 27(45), 5894-5903 (2008).
    • (2008) Oncogene , vol.27 , Issue.45 , pp. 5894-5903
    • Stewart, T.J.1    Abrams, S.I.2
  • 74
    • 49649105571 scopus 로고    scopus 로고
    • Hypoxia increases tumor cell shedding of MHC class I chain-related molecule: Role of nitric oxide
    • Siemens DR, Hu N, Sheikhi AK et al. Hypoxia increases tumor cell shedding of MHC class I chain-related molecule: role of nitric oxide. Cancer Res. 68(12), 4746-4753 (2008).
    • (2008) Cancer Res. , vol.68 , Issue.12 , pp. 4746-4753
    • Siemens, D.R.1    Hu, N.2    Sheikhi, A.K.3
  • 75
    • 0019139138 scopus 로고
    • Differential expression of H-2 gene products in tumour cells is associated with their metastatogenic properties
    • DOI 10.1038/288179a0
    • De Baetselier P, Katzav S, Gorelik E, Feldman M, Segal S. Differential expression of H 2 gene products in tumour cells in associated with their metastatogenic properties. Nature 288(5787), 179-181 (1980). (Pubitemid 11212608)
    • (1980) Nature , vol.288 , Issue.5787 , pp. 179-181
    • De Baetselier, P.1    Katzav, S.2    Gorelik, E.3
  • 76
    • 80755166229 scopus 로고
    • Changes in MHC antigen expression during tumor progression in the AKR lymphoma
    • Huszar M, Tzur-Lerman A, Eisenbach L, Leibovici J. Changes in MHC antigen expression during tumor progression in the AKR lymphoma. Israel J. Med. Sci. 11, 859-860 (1994).
    • (1994) Israel J. Med. Sci. , vol.11 , pp. 859-860
    • Huszar, M.1    Tzur-Lerman, A.2    Eisenbach, L.3    Leibovici, J.4
  • 77
    • 0022891340 scopus 로고
    • Tumors: Wounds that do not heal: Similarities between tumor stroma generation and wound healing
    • Dvorak HF. Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. N. Engl. J. Med. 315(26), 1650-1659 (1986). (Pubitemid 17052899)
    • (1986) New England Journal of Medicine , vol.315 , Issue.26 , pp. 1650-1659
    • Dvorak, H.F.1
  • 79
    • 19444382439 scopus 로고    scopus 로고
    • Classical and nonclassical HLA class I antigen and NK cell-activating ligand changes in malignant cells: Current challenges and future directions
    • DOI 10.1016/S0065-230X(05)93006-6
    • Chang CC, Campoli M, Ferrone S. Classical and nonclassical HLA class I antigen and NK cell-activating ligand changes in malignant cells: current challenges and future directions. Adv. Cancer Res. 93, 189-234 (2005). (Pubitemid 41557276)
    • (2005) Advances in Cancer Research , vol.93 , pp. 189-234
    • Chang, C.-C.1    Campoli, M.2    Ferrone, S.3
  • 80
    • 0023761696 scopus 로고
    • Recognition and destruction of neoplastic cells by activated macrophages: Discrimination of altered self
    • DOI 10.1016/0304-419X(88)90009-1
    • Fidler IJ, Schroit AJ. Recognition and destruction of neoplastic cells by activated macrophages: discrimination of altered self. Biochim. Biophys. Acta 948(2), 151-173 (1988). (Pubitemid 18263873)
    • (1988) Biochimica et Biophysica Acta - Reviews on Cancer , vol.948 , Issue.2 , pp. 151-173
    • Fidler, I.J.1    Schroit, A.J.2
  • 81
    • 0036187615 scopus 로고    scopus 로고
    • The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies
    • DOI 10.1002/path.1027
    • Bingle L, Brown NJ, Lewis CE. The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies. J. Pathol. 196(3), 254-265 (2002). (Pubitemid 34189413)
    • (2002) Journal of Pathology , vol.196 , Issue.3 , pp. 254-265
    • Bingle, L.1    Brown, N.J.2    Lewis, C.E.3
  • 82
    • 73649093148 scopus 로고    scopus 로고
    • Folate receptor b is expressed by tumor-associated macrophages and constitutes a marker for M2 anti-inflammatory/regulatory macrophages
    • Puig-Kroger A, Sierra-Filardi E, Dominguez Soto A et al. Folate receptor b is expressed by tumor-associated macrophages and constitutes a marker for M2 anti-inflammatory/regulatory macrophages. Cancer Res. 69(24), 9395-9403 (2009).
    • (2009) Cancer Res. , vol.69 , Issue.24 , pp. 9395-9403
    • Puig-Kroger, A.1    Sierra-Filardi, E.2    Dominguez Soto, A.3
  • 83
    • 28544446111 scopus 로고    scopus 로고
    • Monocyte and macrophage heterogeneity
    • DOI 10.1038/nri1733
    • Gordon S, Taylor PR. Monocyte and macrophage heterogeneity. Nat. Rev. Immunol. 5(12), 953-964 (2005). (Pubitemid 41746764)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.12 , pp. 953-964
    • Gordon, S.1    Taylor, P.R.2
  • 84
    • 0036839143 scopus 로고    scopus 로고
    • Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
    • DOI 10.1016/S1471-4906(02)02302-5, PII S1471490602023025
    • Mantovani A, Sozzani S, Locati M, Allavena P, Sica A. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol. 23(11), 549-555 (2002). (Pubitemid 35223554)
    • (2002) Trends in Immunology , vol.23 , Issue.11 , pp. 549-555
    • Mantovani, A.1    Sozzani, S.2    Locati, M.3    Allavena, P.4    Sica, A.5
  • 85
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • DOI 10.1038/nri978
    • Gordon S. Alternative activation of macrophages. Nat. Rev. Immunol. 3(1), 23-35 (2003). (Pubitemid 37328697)
    • (2003) Nature Reviews Immunology , vol.3 , Issue.1 , pp. 23-35
    • Gordon, S.1
  • 87
    • 46249090513 scopus 로고    scopus 로고
    • Colony-stimulating factors in inflammation and autoimmunity
    • DOI 10.1038/nri2356, PII NRI2356
    • Hamilton JA. Colony-stimulating factors in inflammation and autoimmunity. Nat. Rev. Immunol. 8(7), 533-544 (2008). (Pubitemid 351913679)
    • (2008) Nature Reviews Immunology , vol.8 , Issue.7 , pp. 533-544
    • Hamilton, J.A.1
  • 89
    • 76149146398 scopus 로고    scopus 로고
    • IL 4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion
    • Gocheva V, Wang HW, Gadea BB et al. IL 4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion. Genes Dev. 24(3), 241-255 (2010).
    • (2010) Genes Dev. , vol.24 , Issue.3 , pp. 241-255
    • Gocheva, V.1    Wang, H.W.2    Gadea, B.B.3
  • 91
    • 76549119724 scopus 로고    scopus 로고
    • La mala educacion of tumor-associated macrophages: Diverse pathways and new players
    • Mantovani A. La mala educacion of tumor-associated macrophages: diverse pathways and new players. Cancer Cell 17(2), 111-112 (2010).
    • (2010) Cancer Cell , vol.17 , Issue.2 , pp. 111-112
    • Mantovani, A.1
  • 92
    • 34248172324 scopus 로고    scopus 로고
    • Altered macrophage differentiation and immune dysfunction in tumor development
    • DOI 10.1172/JCI31422
    • Sica A, Bronte V. Altered macrophage differentiation and immune dysfunction in tumor development. J. Clin. Invest. 117(5), 1155-1166 (2007). (Pubitemid 46718400)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.5 , pp. 1155-1166
    • Sica, A.1    Bronte, V.2
  • 97
    • 41149148269 scopus 로고    scopus 로고
    • Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: Mechanisms and therapeutic perspectives
    • DOI 10.1111/j.1600-065X.2008.00608.x
    • Rodriguez PC, Ochoa AC. Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives. Immunol. Rev. 222, 180-191 (2008). (Pubitemid 351430370)
    • (2008) Immunological Reviews , vol.222 , Issue.1 , pp. 180-191
    • Rodriguez, P.C.1    Ochoa, A.C.2
  • 98
    • 24944587964 scopus 로고    scopus 로고
    • Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors
    • DOI 10.1016/j.ccr.2005.08.002, PII S1535610805002606
    • De Palma M, Venneri MA, Galli R et al. Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors. Cancer Cell 8(3), 211-226 (2005). (Pubitemid 41317592)
    • (2005) Cancer Cell , vol.8 , Issue.3 , pp. 211-226
    • De Palma, M.1    Venneri, M.A.2    Galli, R.3    Sergi, L.S.4    Politi, L.S.5    Sampaolesi, M.6    Naldini, L.7
  • 99
    • 39049126521 scopus 로고    scopus 로고
    • Tie2-expressing monocytes: Regulation of tumor angiogenesis and therapeutic implications
    • De Palma M, Murdoch C, Venneri MA, Naldini L, Lewis CE. Tie2-expressing monocytes: regulation of tumor angiogenesis and therapeutic implications. Trends Immunol. 28(12), 519-524 (2007).
    • (2007) Trends Immunol. , vol.28 , Issue.12 , pp. 519-524
    • De Palma, M.1    Murdoch, C.2    Venneri, M.A.3    Naldini, L.4    Lewis, C.E.5
  • 100
    • 77954369555 scopus 로고    scopus 로고
    • Angiopoietin 2 regulates gene expression in TIE-expressing monocytes and augments their inherent proangiogenic functions
    • Coffelt SB, Tal AO, Scholz A et al. Angiopoietin 2 regulates gene expression in TIE-expressing monocytes and augments their inherent proangiogenic functions. Cancer Res. 70(13), 5270-5280 (2010).
    • (2010) Cancer Res. , vol.70 , Issue.13 , pp. 5270-5280
    • Coffelt, S.B.1    Tal, A.O.2    Scholz, A.3
  • 101
    • 68949150545 scopus 로고    scopus 로고
    • Tie2-expressing TEM novel targets and vehicles of anticancer therapy
    • De Palma M Naldini L. Tie2-expressing (TEM).Novel targets and vehicles of anticancer therapy? Biochim. Biophys. Acta 1796(1) 5-10 (2009).
    • (2009) Biochim. Biophys. Acta , vol.1796 , Issue.1 , pp. 5-10
    • De Palma, M.1    Naldini, L.2
  • 102
    • 69249222379 scopus 로고    scopus 로고
    • Polarization of tumor-associated neutrophil phenotype by TGF β-b:i N1 versus N2 TAN
    • Fridlender ZG, Sun J, Kim S et al. Polarization of tumor-associated neutrophil phenotype by TGF β-b: "N1" versus "N2" TAN. Cancer Cell 16(3), 183-194 (2009).
    • (2009) Cancer Cell , vol.16 , Issue.3 , pp. 183-194
    • Fridlender, Z.G.1    Sun, J.2    Kim, S.3
  • 104
    • 0028796259 scopus 로고
    • Impairment of lymphocyte locomotion in the tumor microenvironment and the effect of systemic immunotherapy with liposome-encapsulated muramyl-tripeptide-phosphatidylethanolamine
    • Risin D, Kleinerman ES, Umezu Y, Pizzini RP, Balch CM, Pellis NR. Impairment of lymphocyte locomotion in the tumor microenvironment and the effect of systemic immunotherapy with liposome-encapsulated muramyl-tripeptide- phosphatidylethanolamine. Cancer Immunol. Immunother. 40(1), 57-64 (1995).
    • (1995) Cancer Immunol. Immunother. , vol.40 , Issue.1 , pp. 57-64
    • Risin, D.1    Kleinerman, E.S.2    Umezu, Y.3    Pizzini, R.P.4    Balch, C.M.5    Pellis, N.R.6
  • 105
    • 20144380706 scopus 로고    scopus 로고
    • Immune selection and emergence of aggressive tumor variants as negative consequences of Fas-mediated cytotoxicity and altered IFN-γ-regulated gene expression
    • DOI 10.1158/0008-5472.CAN-04-4269
    • Liu K, Caldwell SA, Abrams SI. Immune selection and emergence of aggressive tumor variants as negative consequences of Fas-mediated cytotoxicity and altered IFN g-regulated gene expression. Cancer Res. 65(10), 4376-4388 (2005). (Pubitemid 40775677)
    • (2005) Cancer Research , vol.65 , Issue.10 , pp. 4376-4388
    • Liu, K.1    Caldwell, S.A.2    Abrams, S.I.3
  • 106
    • 33847647528 scopus 로고    scopus 로고
    • Regulatory T cells and cancer
    • DOI 10.1016/j.coi.2007.02.004, PII S095279150700012X, Lymphocyte development/Tumour immunology
    • Wang HY, Wang RF. Regulatory T cells and cancer. Curr. Opin Immunol. 19(2), 217-223 (2007). (Pubitemid 46356965)
    • (2007) Current Opinion in Immunology , vol.19 , Issue.2 , pp. 217-223
    • Wang, H.Y.1    Wang, R.-F.2
  • 107
    • 33645286546 scopus 로고    scopus 로고
    • Regulatory T cells tumour immunity and immunotherapy
    • Zou W. Regulatory T cells, tumour immunity and immunotherapy. Nat. Rev. Immunol 6(4), 295-307 (2006).
    • (2006) Nat. Rev. Immunol , vol.6 , Issue.4 , pp. 295-307
    • Zou, W.1
  • 108
    • 34548804503 scopus 로고    scopus 로고
    • Expansion of human T regulatory type 1 cells in the microenvironment of cyclooxygenase 2 overexpressing head and neck squamous cell carcinoma
    • DOI 10.1158/0008-5472.CAN-07-0767
    • Bergmann C, Strauss L, Zeidler R, Lang S, Whiteside TL. Expansion of human T regulatory type 1 cells in the microenvironment of cyclooxygenase 2 overexpressing head and neck squamous cell carcinoma. Cancer Res. 67(18), 8865-8873 (2007). (Pubitemid 47437463)
    • (2007) Cancer Research , vol.67 , Issue.18 , pp. 8865-8873
    • Bergmann, C.1    Strauss, L.2    Zeidler, R.3    Lang, S.4    Whiteside, T.L.5
  • 109
    • 34547655923 scopus 로고    scopus 로고
    • + T cells secreting interleukin-10 and transforming growth factor-β1 mediates suppression in the tumor microenvironment
    • DOI 10.1158/1078-0432.CCR-07-0472
    • +CD25highFoxp3+ T cells secreting interleukin 10 and transforming growth factor b1 mediates suppression in the tumor microenvironment. Clin. Cancer Res. 13(15 Pt 1), 4345-4354 (2007). (Pubitemid 47219698)
    • (2007) Clinical Cancer Research , vol.13 , Issue.15 , pp. 4345-4354
    • Strauss, L.1    Bergmann, C.2    Szczepanski, M.3    Gooding, W.4    Johnson, J.T.5    Whiteside, T.L.6
  • 112
    • 40849086381 scopus 로고    scopus 로고
    • Immunoregulatory T cells: Role and potential as a target in malignancy
    • DOI 10.1007/s11912-008-0021-z
    • Beyer M, Schultze JL. Immunoregulatory T cells: role and potential as a target in malignancy. Curr. Oncol. Rep. 10(2), 130-136 (2008). (Pubitemid 351395473)
    • (2008) Current Oncology Reports , vol.10 , Issue.2 , pp. 130-136
    • Beyer, M.1    Schultze, J.L.2
  • 113
    • 74949120328 scopus 로고    scopus 로고
    • Blocking ovarian cancer progression by targeting tumor microenvironmental leukocytes
    • Cubillos Ruiz JR, Rutkowski M, Conejo Garcia JR. Blocking ovarian cancer progression by targeting tumor microenvironmental leukocytes. Cell Cycle 9(2), 260-268 (2010).
    • (2010) Cell Cycle , vol.9 , Issue.2 , pp. 260-268
    • Cubillos Ruiz, J.R.1    Rutkowski, M.2    Conejo Garcia, J.R.3
  • 118
    • 0029875958 scopus 로고    scopus 로고
    • Antimetastatic and antitumor activities of interleukin 10 in a murine model of breast cancer
    • DOI 10.1093/jnci/88.8.536
    • Kundu N, Beaty TL, Jackson MJ, Fulton AM. Antimetastatic and antitumor activities of interleukin 10 in a murine model of breast cancer. J. Natl. Cancer Inst. 88 (8), 536-541 (1996). (Pubitemid 26118724)
    • (1996) Journal of the National Cancer Institute , vol.88 , Issue.8 , pp. 536-541
    • Kundu, N.1    Beaty, T.L.2    Jackson, M.J.3    Fulton, A.M.4
  • 120
    • 0030724702 scopus 로고    scopus 로고
    • Dendritic cells as mediators of tumor-induced tolerance in metastatic melanoma
    • DOI 10.1002/(SICI)1097-0215(19971104)73:3<309::AID-IJC1>3.0.CO;2-3
    • Enk AH Jonuleit H, Salog J, Knop J. Dendritic cells as mediators of tumor-induced tolerance in metastatic melanoma. Int. J. Cancer 73(3), 309-316 (1997). (Pubitemid 27508890)
    • (1997) International Journal of Cancer , vol.73 , Issue.3 , pp. 309-316
    • Enk, A.H.1    Jonuleit, H.2    Saloga, J.3    Knop, J.4
  • 121
    • 0030950036 scopus 로고    scopus 로고
    • Interleukin 10 is a growth factor for human melanoma cells and down-regulates HLA class I HLA class II and ICAM I molecules
    • Yue FY, Dummer R, Geertsen R et al. Interleukin 10 is a growth factor for human melanoma cells and down-regulates HLA class I, HLA class II and ICAM I molecules. Int. J. Cancer 71(4), 630-637 (1997).
    • (1997) Int. J. Cancer , vol.71 , Issue.4 , pp. 630-637
    • Yue, F.Y.1    Dummer, R.2    Geertsen, R.3
  • 122
    • 27644552384 scopus 로고    scopus 로고
    • Interleukin-10 and the immune response against cancer: A counterpoint
    • DOI 10.1189/jlb.0705358
    • Mocellin S, Marincola FM, Young HA. Interleukin 10 and the immune response agaist cancer: a counterpoint: J. Leuk. Biol. 78(5), 1043-1051 (2005). (Pubitemid 41572467)
    • (2005) Journal of Leukocyte Biology , vol.78 , Issue.5 , pp. 1043-1051
    • Mocellin, S.1    Marincola, F.M.2    Young, H.A.3
  • 123
    • 1642525993 scopus 로고    scopus 로고
    • Importance of IL-10 for CTLA-4-mediated inhibition of tumor-eradicating immunity
    • Jovasevic VM, Gorelik M, Bluestone JA, Mokyr MB. Importance of IL 10 for CTLA 4-mediated inhibition of tumor-eradicating immunity. J. Immunol. 172(3), 1449-1454 (2004). (Pubitemid 38116787)
    • (2004) Journal of Immunology , vol.172 , Issue.3 , pp. 1449-1454
    • Jovasevic, V.M.1    Gorelik, L.2    Bluestone, J.A.3    Mokyr, M.B.4
  • 124
    • 0037136303 scopus 로고    scopus 로고
    • Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody
    • Vicari AP, Chiodoni C, Vaure C. Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody. J. Exp. Med. 196(4) 541-549 (2002).
    • (2002) J. Exp. Med. , vol.196 , Issue.4 , pp. 541-549
    • Vicari, A.P.1    Chiodoni, C.2    Vaure, C.3
  • 125
    • 0033803523 scopus 로고    scopus 로고
    • Inhibition of interleukin 10 IL 10 production from MOPC 315 tumor cells by IL 10 antisense oligodeoxynucleotides enhances cell-mediated immune response
    • Kim BG, Joo HG, Chung IS, Chung HY, Woo HJ, Yun VS. Inhibition of interleukin 10 (IL 10) production from MOPC 315 tumor cells by IL 10 antisense oligodeoxynucleotides enhances cell-mediated immune response. Cancer Immunol. Immunother. 49(8), 433-440 (2000).
    • (2000) Cancer Immunol. Immunother , vol.49 , Issue.8 , pp. 433-440
    • Kim, B.G.1    Joo, H.G.2    Chung, I.S.3    Chung, H.Y.4    Woo, H.J.5    Yun, V.S.6
  • 127
    • 77649184739 scopus 로고    scopus 로고
    • The regulation of IL 10 production by immune cells
    • Saraiva M, O'Garra A. The regulation of IL 10 production by immune cells. Nat. Rev. Immunol. 10(3), 170-181 (2010).
    • (2010) Nat. Rev. Immunol. , vol.10 , Issue.3 , pp. 170-181
    • Saraiva, M.1    O'Garra, A.2
  • 128
    • 0034770605 scopus 로고    scopus 로고
    • Immune-mediated eradication of tumors through the blockade of transforming growth factor-β signaling in T cells
    • DOI 10.1038/nm1001-1118
    • Gorelik L, Flavell RA. Immune-mediated eradication of tumors through the blockade of transforming growth factor b signaling in T cells. Nat. Med. 7(10), 1118-1122 (2001). (Pubitemid 33010019)
    • (2001) Nature Medicine , vol.7 , Issue.10 , pp. 1118-1122
    • Gorelink, L.1    Flavell, R.A.2
  • 130
    • 77950595599 scopus 로고    scopus 로고
    • Targeting the transforming growth factor b signalling pathway in metastatic cancer
    • Korpal M, Kang Y. Targeting the transforming growth factor b signalling pathway in metastatic cancer. Eur. J. Cancer 46(7), 1232-1240 (2010).
    • (2010) Eur. J. Cancer , vol.46 , Issue.7 , pp. 1232-1240
    • Korpal, M.1    Kang, Y.2
  • 131
    • 34247552726 scopus 로고    scopus 로고
    • Stat3 as a potential target for cancer immunotherapy
    • DOI 10.1097/01.cji.0000211327.76266.65, PII 0000237120070200000001
    • Kortylewski M, Yu H. STAT3 as a potential target for cancer immunotherapy. J. Immunother. 30(2), 131-139 (2007). (Pubitemid 46667794)
    • (2007) Journal of Immunotherapy , vol.30 , Issue.2 , pp. 131-139
    • Kortylewski, M.1    Yu, H.2
  • 132
    • 1042302005 scopus 로고    scopus 로고
    • The stats of cancer - New molecular targets come of age
    • Yu H, Jove R. The STATs of cancer - new molecular targets come of age. Nat. Rev. Cancer 4(2), 97-105 (2004). (Pubitemid 38198738)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.2 , pp. 97-105
    • Yu, H.1    Jove, R.2
  • 133
    • 77957701558 scopus 로고    scopus 로고
    • The PD 1/PD L1 axis modulates the natural killer cell versus multiple myeloma effect: A therapeutic target for CT 011 a novel monoclonal anti-PD 1 antibody
    • Benson DM JR, Bakan CE, Mishra A et al. The PD 1/PD L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT 011, a novel monoclonal anti-PD 1 antibody. Blood 116(13), 2286-2294 (2010).
    • (2010) Blood , vol.116 , Issue.13 , pp. 2286-2294
    • Benson, Jr.D.M.1    Bakan, C.E.2    Mishra, A.3
  • 134
    • 80052476869 scopus 로고    scopus 로고
    • High expression of PD L1 in lung cancer may contribute to poor prognosis and tumor cells immune escape through suppressing tumor infiltrating dendritic cells maturation
    • Mu CY, Huang JA, Chen Y, Chen C, Zhang XG. High expression of PD L1 in lung cancer may contribute to poor prognosis and tumor cells immune escape through suppressing tumor infiltrating dendritic cells maturation. Med. Oncol. 28(3), 682-688 (2010).
    • (2010) Med. Oncol. , vol.28 , Issue.3 , pp. 682-688
    • Mu, C.Y.1    Huang, J.A.2    Chen, Y.3    Chen, C.4    Zhang, X.G.5
  • 136
    • 77950283280 scopus 로고    scopus 로고
    • Tumor cell expression of programmed cell death-1 ligand 1 is a prognostic factor for malignant melanoma
    • Hino R, Kabashima K, Kato Y et al. Tumor cell expression of programmed cell death-1 ligand 1 is a prognostic factor for malignant melanoma. Cancer 116(7), 1757-1766 (2010).
    • (2010) Cancer , vol.116 , Issue.7 , pp. 1757-1766
    • Hino, R.1    Kabashima, K.2    Kato, Y.3
  • 138
    • 79952775415 scopus 로고    scopus 로고
    • Clinical development of mAbs to block the PD1 pathway as an immunotherapy for cancer
    • Kline J, Gajewski TF. Clinical development of mAbs to block the PD1 pathway as an immunotherapy for cancer. Curr. Opin Investig. Drugs 11(12), 1354-1359 (2010).
    • (2010) Curr. Opin Investig. Drugs , vol.11 , Issue.12 , pp. 1354-1359
    • Kline, J.1    Gajewski, T.F.2
  • 139
    • 34248173331 scopus 로고    scopus 로고
    • Indoleamine 2 3 dioxygenase and tumor-induced tolerance
    • Munn DH, Mellor AL. Indoleamine 2,3 dioxygenase and tumor-induced tolerance. J. Clin. Invest. 117(5), 1147-1154 (2007).
    • (2007) J. Clin. Invest. , vol.117 , Issue.5 , pp. 1147-1154
    • Munn, D.H.1    Mellor, A.L.2
  • 141
    • 34547663303 scopus 로고    scopus 로고
    • Tumor immune escape mediated by indoleamine 2,3-dioxygenase
    • DOI 10.1016/j.imlet.2007.06.001, PII S0165247807001241
    • Zamanakou M, Germenis AE, Karanikas V. Tumor immune escape mediated by indoleamine 2,3 dioxygenase. Immunol. Lett. 111(2), 69-75 (2007). (Pubitemid 47212491)
    • (2007) Immunology Letters , vol.111 , Issue.2 , pp. 69-75
    • Zamanakou, M.1    Germenis, A.E.2    Karanikas, V.3
  • 143
    • 16244408626 scopus 로고    scopus 로고
    • Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy
    • DOI 10.1038/nm1196
    • Muller AJ, Duhadaway JB, Donover PS, Sutanto Ward E, Prendergast GC. Inhibition of indoleamine 2,3 dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy. Nat. Med. 11(3), 312-319 (2005). (Pubitemid 40460560)
    • (2005) Nature Medicine , vol.11 , Issue.3 , pp. 312-319
    • Muller, A.J.1    DuHadaway, J.B.2    Donover, P.S.3    Sutanto-Ward, E.4    Prendergast, G.C.5
  • 144
    • 77952801325 scopus 로고    scopus 로고
    • Hypoxia modulates EWS FLI1 transcriptional signature and enhances the malignant properties of ewings sarcoma cells in vitro
    • Aryee DN, Niedan S, Kauer M et al. Hypoxia modulates EWS FLI1 transcriptional signature and enhances the malignant properties of Ewing's sarcoma cells in vitro. Cancer Res. 70(10), 4015-4023 (2010).
    • (2010) Cancer Res. , vol.70 , Issue.10 , pp. 4015-4023
    • Aryee, D.N.1    Niedan, S.2    Kauer, M.3
  • 145
    • 58149147369 scopus 로고    scopus 로고
    • Hypoxia-adenosinergic immunosuppression: Tumor protection by T regulatory cells and cancerous tissue hypoxia
    • Sitkovsky MV, Kjaergaard J, Lukashev D, Ohta A. Hypoxia-adenosinergic immunosuppression: tumor protection by T regulatory cells and cancerous tissue hypoxia. Clin. Cancer Res. 14(19), 5947-5952 (2008).
    • (2008) Clin. Cancer Res. , vol.14 , Issue.19 , pp. 5947-5952
    • Sitkovsky, M.V.1    Kjaergaard, J.2    Lukashev, D.3    Ohta, A.4
  • 146
    • 40249106427 scopus 로고    scopus 로고
    • Inhibition of T cell and natural killer cell function by adenosine and its contribution to immune evasion by tumor cells (Review)
    • Hoskin DW, Mader JS, Furlong S, Conrad DM, Blay J. Inhibition of T cell and natural killer cell function by adenosine and its contribution to immune evasion by tumor cells (review).Int. J. Oncol. 32(3), 527-535 (2008). (Pubitemid 351330458)
    • (2008) International Journal of Oncology , vol.32 , Issue.3 , pp. 527-535
    • Hoskin, D.W.1    Mader, J.S.2    Furlong, S.J.3    Conrad, D.M.4    Blay, J.5
  • 147
    • 0342804262 scopus 로고    scopus 로고
    • An acidic microenvironment inhibits antitumoral non-major histocompatibility complex-restricted cytotoxicity: Implications for cancer immunotherapy
    • DOI 10.1097/00002371-200003000-00004
    • Fischer B, Muller B, Fisch P, Kreutz W. An acidic microenvironment inhibits antitumoral non-major histocompatibility complex-restricted cytotoxicity: implications for cancer immunotherapy. J. Immunother. 23(2), 196-207 (2000). (Pubitemid 30165169)
    • (2000) Journal of Immunotherapy , vol.23 , Issue.2 , pp. 196-207
    • Fischer, B.1    Muller, B.2    Fisch, P.3    Kreutz, W.4
  • 148
    • 77749264278 scopus 로고    scopus 로고
    • Alternatively activated macrophages and collagen remodeling characterize the postpartum involuting mammary gland across species
    • O'Brien J, Lyons T, Monks J et al. Alternatively activated macrophages and collagen remodeling characterize the postpartum involuting mammary gland across species. Am. J. Pathol. 176(3), 1241-1255 (2010).
    • (2010) Am. J. Pathol. , vol.176 , Issue.3 , pp. 1241-1255
    • O'Brien, J.1    Lyons, T.2    Monks, J.3
  • 149
    • 76249106734 scopus 로고    scopus 로고
    • Gene expression analysis of macrophages that facilitate tumor invasion supports a role for Wnt-signaling in mediating their activity in primary mammary tumors
    • Ojalvo LS, Whittaker CA, Condeelis JS, Pollard JW. Gene expression analysis of macrophages that facilitate tumor invasion supports a role for Wnt-signaling in mediating their activity in primary mammary tumors. J. Immunol. 184(2), 702-712 (2010).
    • (2010) J. Immunol. , vol.184 , Issue.2 , pp. 702-712
    • Ojalvo, L.S.1    Whittaker, C.A.2    Condeelis, J.S.3    Pollard, J.W.4
  • 150
    • 0022115782 scopus 로고
    • Lysis and growth stimulation of a murine melanoma determined by density of macrophage populations
    • Leibovici J, Hoenig S. Lysis and growth stimulation of a murine melanoma determined by density of macrophage populations. Anticancer Res. 5(5), 545-551 (1985).
    • (1985) Anticancer Res. , vol.5 , Issue.5 , pp. 545-551
    • Leibovici, J.1    Hoenig, S.2
  • 151
    • 62549109923 scopus 로고    scopus 로고
    • High-density gene expression analysis of tumor-associated macrophages from mouse mammary tumors
    • Ojalvo LS, King W, Cox D, Pollard JW. High-density gene expression analysis of tumor-associated macrophages from mouse mammary tumors. Am. J. Pathol. 174(3), 1048-1064 (2009).
    • (2009) Am. J. Pathol. , vol.174 , Issue.3 , pp. 1048-1064
    • Ojalvo, L.S.1    King, W.2    Cox, D.3    Pollard, J.W.4
  • 152
    • 77953169923 scopus 로고    scopus 로고
    • ADAMTS1 contributes to the acquisition of an endothelial-like phenotype in plastic tumor cells
    • Casal C, Torres-Collado AX, Plaza Calonge Mdel C et al. ADAMTS1 contributes to the acquisition of an endothelial-like phenotype in plastic tumor cells. Cancer Res. 70(11), 4676-4686 (2010).
    • (2010) Cancer Res. , vol.70 , Issue.11 , pp. 4676-4686
    • Casal, C.1    Torres-Collado, A.X.2    Plaza Calonge Mdel, C.3
  • 153
    • 0037096876 scopus 로고    scopus 로고
    • Constitutive activation of signal transducers and activators of transcription 3 correlates with cyclin D1 overexpression and may provide a novel prognostic marker in head and neck squamous cell carcinoma
    • Masuda M, Suzui M, Yasumatu R et al. Constitutive activation of signal transducers and activators of transcription 3 correlates with cyclin D1 overexpression and may provide a novel prognostic marker in head and neck squamous cell carcinoma. Cancer Res. 62(12), 3351-3355 (2002). (Pubitemid 34651376)
    • (2002) Cancer Research , vol.62 , Issue.12 , pp. 3351-3355
    • Masuda, M.1    Suzui, M.2    Yasumatu, R.3    Nakashima, T.4    Kuratomi, Y.5    Azuma, K.6    Tomita, K.7    Komiyama, S.8    Weinstein, I.B.9
  • 156
    • 2442685645 scopus 로고    scopus 로고
    • Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis
    • DOI 10.1038/sj.onc.1207383
    • Xie TX, Wei D, Liu M et al. STAT3 activation regulates the expression of matrix metalloproteinase 2 and tumor invasion and metastasis. Oncogene 23(20), 3550-3560 (2004). (Pubitemid 38658421)
    • (2004) Oncogene , vol.23 , Issue.20 , pp. 3550-3560
    • Xie, T.-X.1    Wei, D.2    Liu, M.3    Gao, A.C.4    Ali-Osman, F.5    Sawaya, R.6    Huang, S.7
  • 162
    • 34247874642 scopus 로고    scopus 로고
    • Decreased macrophage number and activation lead to reduced lymphatic vessel formation and contribute to impaired diabetic wound healing
    • Maruyama K, Asai J, Ii M et al. Decreased macrophage number and activation lead to reduced lymphatic vessel formation and contribute to impaired diabetic wound healing. Am. J. Pathol. 170(4), 1178-1191 (2007).
    • (2007) Am. J. Pathol. , vol.170 , Issue.4 , pp. 1178-1191
    • Maruyama, K.1    Asai, J.2    Ii, M.3
  • 164
    • 79953151458 scopus 로고    scopus 로고
    • Cancer immunoediting: Integrating immunity's roles in cancer suppression and promoting
    • Schreiber RD, Old LJ, Smyth MJ. Cancer immunoediting: integrating immunity's roles in cancer suppression and promoting. Science 331(6024), 1565-1570 (2011).
    • (2011) Science , vol.331 , Issue.6024 , pp. 1565-1570
    • Schreiber, R.D.1    Old, L.J.2    Smyth, M.J.3
  • 165
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 144(5), 646-674 (2011).
    • (2011) Cell , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2


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