Site-specific metastasis formation: Chemokines as regulators of tumor cell adhesion, motility and invasion

Cell Adhesion and Migration

Volumn 3, Issue 4, 2009, Pages

  Ben Baruch, Adit ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

Adhesion; Cancer; Chemokines; CXCL12; CXCR4; Invasion; Metastasis; Migration

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; FOCAL ADHESION KINASE; FOCAL ADHESION KINASE 2; PROTEIN CDC42; RAC PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; STROMAL CELL DERIVED FACTOR 1; CHEMOKINE;

CANCER INVASION; CELL ADHESION; CELL MIGRATION; CELL MOTILITY; HUMAN; METASTASIS; MICROENVIRONMENT; NOTE; TUMOR CELL; ANIMAL; CELL MOTION; PHYSIOLOGY; REVIEW;

ANIMALS; CELL ADHESION; CELL MOVEMENT; CHEMOKINES; HUMANS; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS;

EID: 85011940682     PISSN: 19336918     EISSN: 19336926     Source Type: Journal    
DOI: None     Document Type: Note

References (30)

1. Fidler IJ. The organ microenvironment and cancer metastasis. Differentiation 2002; 70:498-505
2. Fidler IJ. The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nat Rev Cancer 2003; 3:453-458
3. Park CC, Bissell MJ, Barcellos-Hoff MH. The influence of the microenvironment on the malignant phenotype. Mol Med Today 2000; 6:324-329
4. Gassmann P, Enns A, Haier J. Role of tumor cell adhesion and migration in organspecific metastasis formation. Onkologie 2004; 27:577-582 (Pubitemid 39664155)
5. Rot A, von Andrian UH. Chemokines in innate and adaptive host defense: basic chemokinese grammar for immune cells. Annu Rev Immunol 2004; 22:891-928 (Pubitemid 38680444)
6. Bacon K, Baggiolini M, Broxmeyer H, Horuk R, Lindley I, Mantovani A, et al. Chemokine/chemokine receptor nomenclature. J Interferon Cytokine Res 2002; 22:1067-1068
7. Sallusto F, Mackay CR, Lanzavecchia A. The role of chemokine receptors in primary, effector, and memory immune responses. Annu Rev Immunol 2000; 18:593-620 (Pubitemid 30365392)
8. Zlotnik A, Yoshie O. Chemokines: a new classification system and their role in immunity. Immunity 2000;12: 121-127 (Pubitemid 30398626)
9. Muller A, Homey B, Soto H, Ge N, Catron D, Buchanan ME, et al. Involvement of chemokine receptors in breast cancer metastasis. Nature 2001; 410:50-56 (Pubitemid 32225831)
10. Zlotnik A. New insights on the role of CXCR4 in cancer metastasis. J Pathol 2008; 215:211-213 (Pubitemid 351956701)
11. Zlotnik A. Chemokines and cancer. Int J Cancer 2006;119:2026-2029
12. Ben-Baruch A. The multifaceted roles of chemokines in malignancy. Cancer Metastasis Rev 2006;25:357-371
13. Ben-Baruch A. Organ selectivity in metastasis: regulation by chemokines and their receptors. Clin Exp Metastasis 2008; 25:345-356 (Pubitemid 351748979)
14. Balkwill F. The significance of cancer cell expression of the chemokine receptor CXCR4. Semin Cancer Biol 2004; 14:171-179 (Pubitemid 38586742)
15. Wang J, Loberg R, Taichman RS. The pivotal role of CXCL12 (SDF-1)/CXCR4 axis in bone metastasis. Cancer Metastasis Rev 2006; 25:573-577 (Pubitemid 46071864)
16. Fulton AM. The chemokine receptors CXCR4 and CXCR3 in cancer. Curr Oncol Rep 2009; 11:125-131
17. Thelen M, Thelen S. CXCR7, CXCR4 and CXCL12: an eccentric trio? J Neuroimmunol 2008; 198:9-13
18. Prasad A, Fernandis AZ, Rao Y, Ganju RK. Slit protein-mediated inhibition of CXCR4- induced chemotactic and chemoinvasive signaling pathways in breast cancer cells. J Biol Chem 2004; 279:9115-9124 (Pubitemid 38295976)
19. Fernandis AZ, Prasad A, Band H, Klosel R, Ganju RK. Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells. Oncogene 2004; 23:157-167 (Pubitemid 38142250)
20. Lee BC, Lee TH, Avraham S, Avraham HK. Involvement of the chemokine receptor CXCR4 and its ligand stromal cell-derived factor 1alpha in breast cancer cell migration through human brain microvascular endothelial cells. Mol Cancer Res 2004; 2:327-338 (Pubitemid 39025295)
21. Denoyelle C, Hong L, Vannier JP, Soria J, Soria C. New insights into the actions of bisphosphonate zoledronic acid in breast cancer cells by dual RhoA-dependent and -independent effects. Br J Cancer 2003; 88:1631-1640 (Pubitemid 36713793)
22. Holland JD, Kochetkova M, Akekawatchai C, Dottore M, Lopez A, McColl SR. Differential functional activation of chemokine receptor CXCR4 is mediated by G proteins in breast cancer cells. Cancer Res 2006; 66:4117-4124
23. Kelly P, Moeller BJ, Juneja J, Booden MA, Der CJ, Daaka Y, et al. The G12 family of heterotrimeric G proteins promotes breast cancer invasion and metastasis. Proc Natl Acad Sci USA 2006; 103:8173-8178 (Pubitemid 43801071)
24. Bartolome RA, Galvez BG, Longo N, Baleux F, Van Muijen GN, Sanchez-Mateos P, et al. Stromal cell-derived factor-1alpha promotes melanoma cell invasion across basement membranes involving stimulation of membrane-type 1 matrix metalloproteinase and Rho GTPase activities. Cancer Res 2004; 64:2534-2543 (Pubitemid 38523910)
25. Bartolome RA, Molina-Ortiz I, Samaniego R, Sanchez-Mateos P, Bustelo XR, Teixido J. Activation of Vav/Rho GTPase signaling by CXCL12 controls membrane-type matrix metalloproteinase-dependent melanoma cell invasion. Cancer Res 2006; 66:248-258 (Pubitemid 43166031)
26. Bartolome RA, Wright N, Molina-Ortiz I, Sanchez-Luque FJ, Teixido J. Activated G(alpha)13 impairs cell invasiveness through p190RhoGAP-mediated inhibition of RhoA activity. Cancer Res 2008; 68:8221-8230
27. Bartolome RA, Ferreiro S, Miquilena-Colina ME, Martinez-Prats L, Soto-Montenegro ML, Garcia-Bernal D, et al. The chemokine receptor CXCR4 and the metalloproteinase MT1-MMP are mutually required during melanoma metastasis to lungs. Am J Pathol. 2009; 174:602-612
28. Kelly P, Stemmle LN, Madden JF, Fields TA, Daaka Y, Casey PJ. A role for the G12 family of heterotrimeric G proteins in prostate cancer invasion. J Biol Chem 2006; 281:26483-26490 (Pubitemid 44401857)
29. Lepley D, Paik JH, Hla T, Ferrer F. The G protein-coupled receptor S1P2 regulates Rho/ Rho kinase pathway to inhibit tumor cell migration. Cancer Res 2005; 65:3788-3795 (Pubitemid 40616357)
30. Tan W, Martin D, Gutkind JS. The Galpha13-Rho signaling axis is required for SDF-1- induced migration through CXCR4. J Biol Chem 2006; 281:39542-39549 (Pubitemid 46041914)