Methods for activity analysis of the proteins that regulate histone methylation

Current Chemical Genomics

Volumn 5, Issue SPEC. ISSUE 1, 2011, Pages 95-105

  Quinn, Amy M ^a,b   Simeonov, Anton ^a  

^a NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^b GLAXOSMITHKLINE   (United States)

Author keywords

Arginine methyltransferase; Enzyme assays; Epigenetics; Histone methylation; Lysine demethylase; Lysine methyltransferase; Protein protein interactions; Reader domain; Small molecule inhibitors

Indexed keywords

2,4 PYRIDINEDICARBOXYLIC ACID DERIVATIVE; 8 QUINOLINOL DERIVATIVE; ALLANTODAPSONE; AMI 1; AMI 5; BETA LAPACHONE; BIGUANIDE DERIVATIVE; BISGUANIDINE DERIVATIVE; BIX 01294; BIX 01338; CHETOCIN; DISULFIRAM; E 70; HISTONE DEMETHYLASE; HYDROXAMIC ACID DERIVATIVE; METHYLTRANSFERASE INHIBITOR; MYRICETIN; PARGYLINE; PYRAZOLE AMIDE; RM 65; SELENIUM DERIVATIVE; SINEFUNGIN; STILBAMIDINE; TRANYLCYPROMINE; TRANYLCYPROMINE DERIVATIVE; UNC 0224; UNC 0321; UNCLASSIFIED DRUG;

BINDING AFFINITY; CAPILLARY ELECTROPHORESIS; CHROMATIN STRUCTURE; CRYSTALLOGRAPHY; DRUG SCREENING; ENZYME ASSAY; EPIGENETICS; FLUORESCENCE POLARIZATION; FLUORESCENCE RESONANCE ENERGY TRANSFER; HIGH THROUGHPUT SCREENING; HISTONE ACETYLATION; HISTONE CODE READER DOMAIN; HISTONE METHYLATION; HISTONE PHOSPHORYLATION; HUMAN; IC 50; IMMUNOASSAY; ISOTOPE LABELING; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN PROCESSING; REVIEW; STRUCTURAL HOMOLOGY; TRANSCRIPTION REGULATION;

EID: 80455131102     PISSN: None     EISSN: 18753973     Source Type: Journal    
DOI: 10.2174/1875397301005010095     Document Type: Review

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