Mass spectrometric techniques for label-free high-throughput screening in drug discovery

Analytical Chemistry

Volumn 79, Issue 21, 2007, Pages 8207-8213

  Roddy, Thomas P ^a   Horvath, Christopher R ^a   Stout, Steven J ^a   Kenney, Kristin L ^a   Ho, Pei I ^a   Zhang, Ji Hu ^a   Vickers, Chad ^a   Kaushik, Virendar ^a   Hubbard, Brian ^a   Karen Wang, Y ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG PRODUCTS; ENZYME INHIBITION; FLUORESCENCE SPECTROSCOPY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; SUBSTRATES;

ENZYMATIC TARGET INHIBITION; HIGH-THROUGHPUT SCREENING (HTS); MEMBRANEOUS ENZYMES; SOLID-PHASE EXTRACTION (SPE);

DRUG THERAPY;

ENZYME;

ARTICLE; DRUG RESEARCH; ENZYME PURIFICATION; FLOW INJECTION ANALYSIS; HIGH THROUGHPUT SCREENING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; TANDEM MASS SPECTROMETRY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COMBINATORIAL CHEMISTRY TECHNIQUES; DRUG EVALUATION, PRECLINICAL; PHARMACEUTICAL PREPARATIONS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

EID: 35848962300     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac062421q     Document Type: Article

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