Target-based approach to inhibitors of histone arginine methyltransferases

Journal of Medicinal Chemistry

Volumn 50, Issue 10, 2007, Pages 2319-2325

  Spannhoff, Astrid ^a   Heinke, Ralf ^b   Bauer, Ingo ^c   Trojer, Patrick ^d   Metzger, Eric ^e   Gust, Ronald ^a   Schüle, Roland ^e   Brosch, Gerald ^c   Sippl, Wolfgang ^b   Jung, Manfred ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^c INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^d RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^e FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMI 1; DAPSONE; HISTONE; METHYLTRANSFERASE INHIBITOR; NSC 113989; NSC 126757; NSC 154983; NSC 20878; NSC 34238; NSC 35605; NSC 46613; NSC 466413; PROTEIN ARGININE METHYLTRANSFERASE; UNCLASSIFIED DRUG;

ARTICLE; ASPERGILLUS NIDULANS; CANCER CELL; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG SCREENING; DRUG STRUCTURE; HUMAN; IN VITRO STUDY; METHYLATION; NONHUMAN; RAT; VALIDATION PROCESS; WESTERN BLOTTING;

ANIMALS; ASPERGILLUS NIDULANS; BENZIMIDAZOLES; BINDING SITES; CELL LINE, TUMOR; CRYSTALLOGRAPHY, X-RAY; DAPSONE; DATABASES, FACTUAL; ESTROGEN RECEPTOR ALPHA; FUNGAL PROTEINS; HISTONES; HUMANS; METHYLATION; MODELS, MOLECULAR; NAPHTHALENES; PROTEIN-ARGININE N-METHYLTRANSFERASE; RATS; REPRESSOR PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION, GENETIC;

EID: 34249066117     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm061250e     Document Type: Article

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