-
1
-
-
34249669497
-
Experimental radiation therapy of tumors with I-131-carrying antibodies to fibrin
-
Bale WF, Spar IL, Goodland RL. Experimental radiation therapy of tumors with I-131-carrying antibodies to fibrin. Cancer Res. 1960;20:1488-1494.
-
(1960)
Cancer Res
, vol.20
, pp. 1488-1494
-
-
Bale, W.F.1
Spar, I.L.2
Goodland, R.L.3
-
2
-
-
0016203571
-
An alkylating agentglobulin conjugate with both alkylating and antibody activity
-
Lindford JH, Froese G, Berczi I, et al. An alkylating agentglobulin conjugate with both alkylating and antibody activity. J Natl Cancer Inst. 1974;52:1665-1667.
-
(1974)
J Natl Cancer Inst
, vol.52
, pp. 1665-1667
-
-
Lindford, J.H.1
Froese, G.2
Berczi, I.3
-
3
-
-
0016756272
-
Continuous cultures of fused cells secreting antibody of predefined specificity
-
Kohler G, Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature. 1975;256: 495-497.
-
(1975)
Nature
, vol.256
, pp. 495-497
-
-
Kohler, G.1
Milstein, C.2
-
4
-
-
33646352962
-
Potent antibody therapeutics by design
-
Carter PJ. Potent antibody therapeutics by design. Nat Rev Immunol. 2006;6:343-357.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 343-357
-
-
Carter, P.J.1
-
5
-
-
78651387929
-
Antibody-based therapeutics to watch in 2011
-
Reichert JM. Antibody-based therapeutics to watch in 2011. MAbs. 2011;3:76-99.
-
(2011)
MAbs
, vol.3
, pp. 76-99
-
-
Reichert, J.M.1
-
6
-
-
84857232585
-
-
ImmunoGen Inc [ImmunoGen Inc.Web site] Accessed September 26,2011
-
ImmunoGen, Inc. Announces Submission of IND for Wholly Owned Product Candidate for Non-Hodgkin's Lymphoma [ImmunoGen, Inc.Web site] 2011. Available at: http://http://phx. corporate-ir.net/phoenix.zhtml?c=97573&p=irol- newsArticle& ID=1609366&highlight=. Accessed September 26, 2011.
-
(2011)
Announces Submission of IND for Wholly Owned Product Candidate for Non-Hodgkin's Lymphoma
-
-
-
7
-
-
84857233327
-
-
ImmunoGen. ImmunoGen Inc (ImmunoGen Inc. Web site) Accessed July 20, 2011
-
ImmunoGen. ImmunoGen, Inc. Announces First Data for its Novel Therapeutic for Ovarian Cancer and Other Carcinomas (ImmunoGen, Inc. Web site) 2011. Available at: http://phx.corporate-ir.net/phoenix.zhtml?c=97573&p=irol-news Article&ID=1545497&highlight. Accessed July 20, 2011.
-
(2011)
Announces First Data for Its Novel Therapeutic for Ovarian Cancer and Other Carcinomas
-
-
-
8
-
-
74849131675
-
Radioimmunotherapy of lymphoma: Bexxar and Zevalin
-
Goldsmith SJ. Radioimmunotherapy of lymphoma: Bexxar and Zevalin. Semin Nucl Med. 2010;40:122-135.
-
(2010)
Semin Nucl Med
, vol.40
, pp. 122-135
-
-
Goldsmith, S.J.1
-
9
-
-
77954681710
-
Inotuzumab ozogamicin as novel therapy in lymphomas
-
Wong BY, Dang NH. Inotuzumab ozogamicin as novel therapy in lymphomas. Expert Opin Biol Ther. 2010;10: 1251-1258.
-
(2010)
Expert Opin Biol Ther
, vol.10
, pp. 1251-1258
-
-
Wong, B.Y.1
Dang, N.H.2
-
10
-
-
79953830127
-
Brentuximab vedotin for the treatment of CD30+ lymphomas
-
Foyil KV, Bartlett NL. Brentuximab vedotin for the treatment of CD30+ lymphomas. Immunotherapy. 2011;3: 475-485.
-
(2011)
Immunotherapy
, vol.3
, pp. 475-485
-
-
Foyil, K.V.1
Bartlett, N.L.2
-
12
-
-
79951898433
-
AMG 386: Profile of a novel angiopoietin antagonist in patients with ovarian cancer
-
Robson EJ, Ghatage P. AMG 386: profile of a novel angiopoietin antagonist in patients with ovarian cancer. Expert Opin Investig Drugs. 2011;20:297-304.
-
(2011)
Expert Opin Investig Drugs
, vol.20
, pp. 297-304
-
-
Robson, E.J.1
Ghatage, P.2
-
13
-
-
80054989315
-
Trastuzumab Emtansine (T-DM1): A novel agent for targeting HER2(+) breast cancer
-
Epub ahead of print
-
Burris HA 3rd, Tibbitts J, Holden SN, et al. Trastuzumab Emtansine (T-DM1): a novel agent for targeting HER2(+) breast cancer. Clin Breast Cancer. 2011. [Epub ahead of print].
-
(2011)
Clin Breast Cancer
-
-
Burris Iii, H.A.1
Tibbitts, J.2
Holden, S.N.3
-
14
-
-
80055008804
-
-
Frankfurt, Germany: MAbs
-
Beck A, Senter PD, Chari RJ. World Antibody Drug Conjugate Summit Europe: February 21 to 23, 2011. Frankfurt, Germany: MAbs; 2011:3.
-
(2011)
World Antibody Drug Conjugate Summit Europe: February 21 to 23,2011
, pp. 3
-
-
Beck, A.1
Senter, P.D.2
Chari, R.J.3
-
15
-
-
80052076003
-
CD30: An important new target in hematologic malignancies
-
Deutsch YE, Tadmor T, Podack ER, et al. CD30: an important new target in hematologic malignancies. Leuk Lymphoma. 2011;52:1641-1654.
-
(2011)
Leuk Lymphoma
, vol.52
, pp. 1641-1654
-
-
Deutsch, Y.E.1
Tadmor, T.2
Podack, E.R.3
-
16
-
-
78049515807
-
Brentuximab vedotin (SGN-35) for relapsed CD30-positive lymphomas
-
Younes A, Bartlett NL, Leonard JP, et al. Brentuximab vedotin (SGN-35) for relapsed CD30-positive lymphomas. N Engl J Med. 2010;363:1812-1821.
-
(2010)
N Engl J Med
, vol.363
, pp. 1812-1821
-
-
Younes, A.1
Bartlett, N.L.2
Leonard, J.P.3
-
17
-
-
79953146631
-
Brentuximab vedotin
-
Brentuximab vedotin. Drugs R D 2011;11:85-95.
-
(2011)
Drugs R D
, vol.11
, pp. 85-95
-
-
-
18
-
-
77950835018
-
Glembatumumab vedotin, a conjugate of an anti-glycoprotein non-metastatic melanoma protein B mAb and monomethyl auristatin e for the treatment of melanoma and breast cancer
-
Naumovski L, Junutula JR. Glembatumumab vedotin, a conjugate of an anti-glycoprotein non-metastatic melanoma protein B mAb and monomethyl auristatin E for the treatment of melanoma and breast cancer. Curr Opin Mol Ther. 2010;12:248-257.
-
(2010)
Curr Opin Mol Ther
, vol.12
, pp. 248-257
-
-
Naumovski, L.1
Junutula, J.R.2
-
19
-
-
79955832182
-
Trastuzumab emtansine: A novel antibody-drug conjugate for HER2-positive breast cancer
-
Burris HA. Trastuzumab emtansine: a novel antibody-drug conjugate for HER2-positive breast cancer. Expert Opin Biol Ther. 2011;11:807-819.
-
(2011)
Expert Opin Biol Ther
, vol.11
, pp. 807-819
-
-
Burris, H.A.1
-
20
-
-
77953200582
-
Trastuzumab emtansine, an antibodydrug conjugate for the treatment of HER2+ metastatic breast cancer
-
Niculescu-Duvaz I. Trastuzumab emtansine, an antibodydrug conjugate for the treatment of HER2+ metastatic breast cancer. Curr Opin Mol Ther. 2010;12:350-360.
-
(2010)
Curr Opin Mol Ther
, vol.12
, pp. 350-360
-
-
Niculescu-Duvaz, I.1
-
21
-
-
84857234890
-
-
ImmunoGen. ImmunoGen Inc [ImmunoGen Inc. Web site] Accessed July 20, 2011
-
ImmunoGen. ImmunoGen, Inc. Announces Encouraging IMGN388 Clinical Data Reported at ASCO [ImmunoGen, Inc. Web site]. 2010. Available at: http://phx.corporate-ir.net/phoenix.zhtml?c=97573&p=irol-newsArticle&ID= 1435268 &highlight=. Accessed July 20, 2011.
-
(2010)
Announces Encouraging IMGN388 Clinical Data Reported at ASCO
-
-
-
22
-
-
4344569693
-
Safety, pharmacokinetics, and biological pharmacodynamics of the immunocytokine EMD 273066 (huKS-IL2): Results of a phase I trial in patients with prostate cancer
-
Ko YJ, Bubley GJ, Weber R, et al. Safety, pharmacokinetics, and biological pharmacodynamics of the immunocytokine EMD 273066 (huKS-IL2): results of a phase I trial in patients with prostate cancer. J Immunother. 2004;27:232-239. (Pubitemid 39118088)
-
(2004)
Journal of Immunotherapy
, vol.27
, Issue.3
, pp. 232-239
-
-
Ko, Y.-J.1
Bubley, G.J.2
Weber, R.3
Redfern, C.4
Gold, D.P.5
Finke, L.6
Kovar, A.7
Dahl, T.8
Gillies, S.D.9
-
24
-
-
77953097101
-
Phase 1 study of AMG 386, a selective angiopoietin 1/2-neutralizing peptibody, in combination with chemotherapy in adults with advanced solid tumors
-
Mita AC, Takimoto CH, Mita M, et al. Phase 1 study of AMG 386, a selective angiopoietin 1/2-neutralizing peptibody, in combination with chemotherapy in adults with advanced solid tumors. Clin Cancer Res. 2010;16:3044-3056.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 3044-3056
-
-
Mita, A.C.1
Takimoto, C.H.2
Mita, M.3
-
25
-
-
70249114453
-
Safety, pharmacokinetics, and antitumor activity of AMG 386, a selective angiopoietin inhibitor, in adult patients with advanced solid tumors
-
Herbst RS, Hong D, Chap L, et al. Safety, pharmacokinetics, and antitumor activity of AMG 386, a selective angiopoietin inhibitor, in adult patients with advanced solid tumors. J Clin Oncol. 2009;27:3557-3565.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3557-3565
-
-
Herbst, R.S.1
Hong, D.2
Chap, L.3
-
28
-
-
84857236377
-
-
ImmunoGen [ImmunoGen, Inc. Web site] Accessed July 20, 2011
-
ImmunoGen. Lorvotuzumab mertansine [ImmunoGen, Inc. Web site]. 2011. Available at: http://www.immunogen.com/wt/page/IMGN901b. Accessed July 20, 2011.
-
(2011)
Lorvotuzumab Mertansine
-
-
-
29
-
-
77957083400
-
Clinical applications of VEGF-trap (aflibercept) in cancer treatment
-
Teng LS, Jin KT, He KF, et al. Clinical applications of VEGF-trap (aflibercept) in cancer treatment. J Chin Med Assoc. 2010;73:449-456.
-
(2010)
J Chin Med Assoc
, vol.73
, pp. 449-456
-
-
Teng, L.S.1
Jin, K.T.2
He, K.F.3
-
30
-
-
77951648118
-
Safety, pharmacokinetics, and preliminary clinical activity of inotuzumab ozogamicin, a novel immunoconjugate for the treatment of B-cell non-Hodgkin's lymphoma: Results of a phase i study
-
Advani A, Coiffier B, Czuczman MS, et al. Safety, pharmacokinetics, and preliminary clinical activity of inotuzumab ozogamicin, a novel immunoconjugate for the treatment of B-cell non-Hodgkin's lymphoma: results of a phase I study. J Clin Oncol. 2010;28:2085-2093.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2085-2093
-
-
Advani, A.1
Coiffier, B.2
Czuczman, M.S.3
-
31
-
-
77954839504
-
Phase i study of inotuzumab ozogamicin (CMC-544) in Japanese patients with follicular lymphoma pretreated with rituximab-based therapy
-
Ogura M, Tobinai K, Hatake K, et al. Phase I study of inotuzumab ozogamicin (CMC-544) in Japanese patients with follicular lymphoma pretreated with rituximab-based therapy. Cancer Sci. 2010;101:1840-1845.
-
(2010)
Cancer Sci
, vol.101
, pp. 1840-1845
-
-
Ogura, M.1
Tobinai, K.2
Hatake, K.3
-
32
-
-
80052387216
-
Clinical outcomes of postremission therapy using (90)yttrium ibritumomab tiuxetan [Zevalin(R)] for high-risk patients with diffuse large B-cell lymphoma
-
Han EJ, Lee SE, Kim SH, et al. Clinical outcomes of postremission therapy using (90)yttrium ibritumomab tiuxetan [Zevalin(R)] for high-risk patients with diffuse large B-cell lymphoma. Ann Hematol. 2011;90:1075-1082.
-
(2011)
Ann Hematol
, vol.90
, pp. 1075-1082
-
-
Han, E.J.1
Lee, S.E.2
Kim, S.H.3
-
33
-
-
75449105595
-
Consensus conference on the use of 90-yttrium-ibritumomab tiuxetan therapy in clinical practice: A project of the Italian society of hematology
-
Vitolo U, Barosi G, Fanti S, et al. Consensus conference on the use of 90-yttrium-ibritumomab tiuxetan therapy in clinical practice: a project of the Italian society of hematology. Am J Hematol. 2010;85:147-155.
-
(2010)
Am J Hematol
, vol.85
, pp. 147-155
-
-
Vitolo, U.1
Barosi, G.2
Fanti, S.3
-
34
-
-
79952687786
-
Yttrium ibritumomab tiuxetan in the treatment of non-Hodgkin's lymphoma: Current status and future prospects
-
Jacobs SA. Yttrium ibritumomab tiuxetan in the treatment of non-Hodgkin's lymphoma: current status and future prospects. Biologics. 2007;1:215-227.
-
(2007)
Biologics
, vol.1
, pp. 215-227
-
-
Jacobs, S.A.1
-
35
-
-
38549174095
-
Immunotherapy in mantle cell lymphoma: Anti-CD20-based therapy and beyond
-
DOI 10.1002/ajh.21036
-
Zhou Y, Zhang L, Romaguera J, et al. Immunotherapy in mantle cell lymphoma: anti-CD20-based therapy and beyond. Am J Hematol. 2008;83:144-149. (Pubitemid 351147782)
-
(2008)
American Journal of Hematology
, vol.83
, Issue.2
, pp. 144-149
-
-
Zhou, Y.1
Zhang, L.2
Romaguera, J.3
Delasalle, K.4
Han, X.5
Du, X.6
Kwak, L.7
Yi, Q.8
Wang, M.9
-
36
-
-
77957272703
-
High rates of durable responses with anti-CD22 fractionated radioimmunotherapy: Results of a multicenter, phase I/II study in non-Hodgkin's lymphoma
-
Morschhauser F, Kraeber-Bodere F, Wegener WA, et al. High rates of durable responses with anti-CD22 fractionated radioimmunotherapy: results of a multicenter, phase I/II study in non-Hodgkin's lymphoma. J Clin Oncol. 2010;28: 3709-3716.
-
(2010)
J Clin Oncol
, vol.28
, pp. 3709-3716
-
-
Morschhauser, F.1
Kraeber-Bodere, F.2
Wegener, W.A.3
-
37
-
-
40849086818
-
18F- fluorodeoxyglucose positron emission tomography
-
DOI 10.3324/haematol.10591
-
Bodet-Milin C, Kraeber-Bodere F, Dupas B, et al. Evaluation of response to fractionated radioimmunotherapy with 90Yepratuzumab in non-Hodgkin's lymphoma by 18F-fluorodeoxyglucose positron emission tomography. Haematologica. 2008;93:390-397. (Pubitemid 351398640)
-
(2008)
Haematologica
, vol.93
, Issue.3
, pp. 390-397
-
-
Bodet-Milin, C.1
Kraeber-Bodere, F.2
Dupas, B.3
Morschhauser, F.4
Gastinne, T.5
Le Gouill, S.6
Campion, L.7
Harousseau, J.-L.8
Wegener, W.A.9
Goldenberg, D.M.10
Huglo, D.11
-
38
-
-
22344437047
-
90Y-radiollabeled, humanized anti-CD22 monoclonal antibody, epratuzumab
-
DOI 10.1158/1078-0432.CCR-05-0172
-
Linden O, Hindorf C, Cavallin-Stahl E, et al. Dosefractionated radioimmunotherapy in non-Hodgkin's lymphoma using DOTA-conjugated, 90Y-radiolabeled, humanized anti-CD22 monoclonal antibody, epratuzumab. Clin Cancer Res. 2005;11:5215-5222. (Pubitemid 41003709)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.14
, pp. 5215-5222
-
-
Linden, O.1
Hindorf, C.2
Cavallin-Stahl, E.3
Wegener, W.A.4
Goldenberg, D.M.5
Horne, H.6
Ohlsson, T.7
Stenberg, L.8
Strand, S.-E.9
Tennvall, J.10
-
39
-
-
0028840870
-
Radioimmunotherapy of interleukin-2R alpha-expressing adult T-cell leukemia with Yttrium-90-labeled anti-Tac
-
Waldmann TA, White JD, Carrasquillo JA, et al. Radioimmunotherapy of interleukin-2R alpha-expressing adult T-cell leukemia with Yttrium-90-labeled anti-Tac. Blood. 1995;86:4063-4075.
-
(1995)
Blood
, vol.86
, pp. 4063-4075
-
-
Waldmann, T.A.1
White, J.D.2
Carrasquillo, J.A.3
-
40
-
-
78649713153
-
Treatment strategies for nodal and gastrointestinal follicular lymphoma: Current status and future development
-
Watanabe T. Treatment strategies for nodal and gastrointestinal follicular lymphoma: current status and future development. World J Gastroenterol. 2010;16:5543-5554.
-
(2010)
World J Gastroenterol
, vol.16
, pp. 5543-5554
-
-
Watanabe, T.1
-
41
-
-
34848851982
-
Radioimmunotherapy for treatment of B-cell lymphomas and other hematologic malignancies
-
DOI 10.1097/MOH.0b013e3282efb17c, PII 0006275220071100000005
-
Park SI, Press OW. Radioimmunotherapy for treatment of B-cell lymphomas and other hematologic malignancies. Curr Opin Hematol. 2007;14:632-638. (Pubitemid 47494079)
-
(2007)
Current Opinion in Hematology
, vol.14
, Issue.6
, pp. 632-638
-
-
Park, S.I.1
Press, O.W.2
-
42
-
-
78650991430
-
Radioimmunotherapy of relapsed indolent non-Hodgkin lymphoma with 131I-rituximab in routine clinical practice: 10-year single-institution experience of 142 consecutive patients
-
Leahy MF, Turner JH. Radioimmunotherapy of relapsed indolent non-Hodgkin lymphoma with 131I-rituximab in routine clinical practice: 10-year single-institution experience of 142 consecutive patients. Blood. 2011;117:45-52.
-
(2011)
Blood
, vol.117
, pp. 45-52
-
-
Leahy, M.F.1
Turner, J.H.2
-
43
-
-
27144491276
-
131I-huA33 in patients with advanced colorectal carcinoma
-
DOI 10.1158/1078-0432.CCR-04-2330
-
Chong G, Lee FT, Hopkins W, et al. Phase I trial of 131IhuA33 in patients with advanced colorectal carcinoma. Clin Cancer Res. 2005;11:4818-4826. (Pubitemid 41568168)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.13
, pp. 4818-4826
-
-
Chong, G.1
Lee, F.T.2
Hopkins, W.3
Tebbutt, N.4
Cebon, J.S.5
Mountain, A.J.6
Chappell, B.7
Papenfuss, A.8
Schleyer, P.9
U Paul10
Murphy, R.11
Wirth, V.12
Smyth, F.E.13
Potasz, N.14
Poon, A.15
Davis, I.D.16
Saunder, T.17
O'Keefe, G.J.18
Burgess, A.W.19
Hoffman, E.W.20
Old, L.J.21
Scott, A.M.22
more..
-
44
-
-
0028013238
-
131I-CC49 in colorectal cancer
-
Murray JL, Macey DJ, Kasi LP, et al. Phase II radioimmunotherapy trial with 131I-CC49 in colorectal cancer. Cancer. 1994;73:1057-1066. (Pubitemid 24046670)
-
(1994)
Cancer
, vol.73
, Issue.SUPPL.
, pp. 1057-1066
-
-
Murray, J.L.1
Macey, D.J.2
Kasi, L.P.3
Rieger, P.4
Cunningham, J.5
Bhadkamkar, V.6
Zhang, H.-Z.7
Schlom, J.8
Rosenblum, M.G.9
Podoloff, D.A.10
-
45
-
-
27244448455
-
131I-cG250 in patients with metastasized clear cell renal cell carcinoma
-
DOI 10.1200/JCO.2005.07.732
-
Brouwers AH, Mulders PF, de Mulder PH, et al. Lack of efficacy of two consecutive treatments of radioimmunotherapy with 131I-cG250 in patients with metastasized clear cell renal cell carcinoma. J Clin Oncol. 2005;23:6540-6548. (Pubitemid 46190246)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.27
, pp. 6540-6548
-
-
Brouwers, A.H.1
Mulders, P.F.A.2
De Mulder, P.H.M.3
Van Den Broek, W.J.M.4
Buijs, W.C.A.M.5
Mala, C.6
Joosten, F.B.M.7
Oosterwijk, E.8
Boerman, O.C.9
Corstens, F.H.M.10
Oyen, W.J.G.11
-
46
-
-
4544260382
-
131I-labeled chimeric G250 in metastatic renal cancer
-
Divgi CR, O'Donoghue JA, Welt S, et al. Phase I clinical trial with fractionated radioimmunotherapy using 131I-labeled chimeric G250 in metastatic renal cancer. J Nucl Med. 2004; 45:1412-1421. (Pubitemid 47618543)
-
(2004)
Journal of Nuclear Medicine
, vol.45
, Issue.8
, pp. 1412-1421
-
-
Divgi, C.R.1
O'Donoghue, J.A.2
Welt, S.3
O'Neel, J.4
Finn, R.5
Motzer, R.J.6
Jungbluth, A.7
Hoffman, E.8
Ritter, G.9
Larson, S.M.10
Old, L.J.11
-
47
-
-
33947504376
-
124I-cG250) and PET in patients with renal masses: A phase I trial
-
DOI 10.1016/S1470-2045(07)70044-X, PII S147020450770044X
-
Divgi CR, Pandit-Taskar N, Jungbluth AA, et al. Preoperative characterisation of clear-cell renal carcinoma using iodine-124-labelled antibody chimeric G250 (124I-cG250) and PET in patients with renal masses: a phase I trial. Lancet Oncol. 2007;8:304-310. (Pubitemid 46464522)
-
(2007)
Lancet Oncology
, vol.8
, Issue.4
, pp. 304-310
-
-
Divgi, C.R.1
Pandit-Taskar, N.2
Jungbluth, A.A.3
Reuter, V.E.4
Gonen, M.5
Ruan, S.6
Pierre, C.7
Nagel, A.8
Pryma, D.A.9
Humm, J.10
Larson, S.M.11
Old, L.J.12
Russo, P.13
-
48
-
-
79957760097
-
The next generation of positron emission tomography radiopharmaceuticals in oncology
-
Rice SL, Roney CA, Daumar P, et al. The next generation of positron emission tomography radiopharmaceuticals in oncology. Semin Nucl Med. 2011;41:265-282.
-
(2011)
Semin Nucl Med
, vol.41
, pp. 265-282
-
-
Rice, S.L.1
Roney, C.A.2
Daumar, P.3
-
49
-
-
0141919750
-
Targeting metastatic prostate cancer with radiolabeled monoclonal antibody J591 to the extracellular domain of prostate specific membrane antigen
-
DOI 10.1097/01.ju.0000091655.77601.0c
-
Bander NH, Trabulsi EJ, Kostakoglu L, et al. Targeting metastatic prostate cancer with radiolabeled monoclonal antibody J591 to the extracellular domain of prostate specific membrane antigen. J Urol. 2003;170:1717-1721. (Pubitemid 37254913)
-
(2003)
Journal of Urology
, vol.170
, Issue.5
, pp. 1717-1721
-
-
Bander, N.H.1
Trabulsi, E.J.2
Kostakoglu, L.3
Yao, D.4
Vallabhajosula, S.5
Smith-jones, P.6
Joyce, M.A.7
Milowsky, M.8
Nanus, D.M.9
Goldsmith, S.J.10
-
50
-
-
80051777429
-
Targeted, activatable, in vivo fluorescence imaging of Prostate-specific Membrane Antigen (PSMA)-positive tumors using the quenched humanized J591 antibody-ICG conjugate
-
Nakajima T, Mitsunaga M, Bander NH, et al. Targeted, activatable, in vivo fluorescence imaging of Prostate-specific Membrane Antigen (PSMA)-positive tumors using the quenched humanized J591 antibody-ICG conjugate. Bioconjug Chem. 2011;22:1700-1705.
-
(2011)
Bioconjug Chem
, vol.22
, pp. 1700-1705
-
-
Nakajima, T.1
Mitsunaga, M.2
Bander, N.H.3
-
51
-
-
70449347055
-
Approach to the patient after relapse of hairy cell leukemia
-
Kreitman RJ, Fitzgerald DJ, Pastan I. Approach to the patient after relapse of hairy cell leukemia. Leuk Lymphoma. 2009;50(Suppl 1):32-37.
-
(2009)
Leuk Lymphoma
, vol.50
, Issue.SUPPL. 1
, pp. 32-37
-
-
Kreitman, R.J.1
Fitzgerald, D.J.2
Pastan, I.3
-
52
-
-
0034001076
-
Phase I trial of recombinant immunotoxin anti-Tac(Fv)-PE38 (LMB-2) in patients with hematologic malignancies
-
Kreitman RJ, Wilson WH, White JD, et al. Phase I trial of recombinant immunotoxin anti-Tac(Fv)-PE38 (LMB-2) in patients with hematologic malignancies. J Clin Oncol. 2000;18:1622-1636. (Pubitemid 30220540)
-
(2000)
Journal of Clinical Oncology
, vol.18
, Issue.8
, pp. 1622-1636
-
-
Kreitman, R.J.1
Wilson, W.H.2
White, J.D.3
Stetler-Stevenson, M.4
Jaffe, E.S.5
Giardina, S.6
Waldmann, T.A.7
Pastan, I.8
-
53
-
-
79957455539
-
Recombinant immunotoxins and other therapies for relapsed/refractory hairy cell leukemia
-
Kreitman RJ, Arons E, Stetler-Stevenson M, et al. Recombinant immunotoxins and other therapies for relapsed/refractory hairy cell leukemia. Leuk Lymphoma. 2011;52(Suppl 2):82-86.
-
(2011)
Leuk Lymphoma
, vol.52
, Issue.SUPPL. 2
, pp. 82-86
-
-
Kreitman, R.J.1
Arons, E.2
Stetler-Stevenson, M.3
-
54
-
-
27244448693
-
Phase I trial of recombinant immunotoxin RFB4(dsFv)-PE38 (BL22) in patients with B-cell malignancies
-
DOI 10.1200/JCO.2005.11.437
-
Kreitman RJ, Squires DR, Stetler-Stevenson M, et al. Phase I trial of recombinant immunotoxin RFB4(dsFv)-PE38 (BL22) in patients with B-cell malignancies. J Clin Oncol. 2005; 23:6719-6729. (Pubitemid 46190267)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.27
, pp. 6719-6729
-
-
Kreitman, R.J.1
Squires, D.R.2
Stetler-Stevenson, M.3
Noel, P.4
FitzGerald, D.J.P.5
Wilson, W.H.6
Pastan, I.7
-
55
-
-
69349100450
-
Phase i trial of continuous infusion anti-mesothelin recombinant immunotoxin SS1P
-
Kreitman RJ, Hassan R, Fitzgerald DJ, et al. Phase I trial of continuous infusion anti-mesothelin recombinant immunotoxin SS1P. Clin Cancer Res. 2009;15:5274-5279.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5274-5279
-
-
Kreitman, R.J.1
Hassan, R.2
Fitzgerald, D.J.3
-
56
-
-
34548858453
-
Phase I study of SS1P, a recombinant anti-mesothelin immunotoxin given as a bolus I.V. infusion to patients with mesothelin-expressing mesothelioma, ovarian, and pancreatic cancers
-
DOI 10.1158/1078-0432.CCR-07-0869
-
Hassan R, Bullock S, Premkumar A, et al. Phase I study of SS1P, a recombinant anti-mesothelin immunotoxin given as a bolus I.V. infusion to patients with mesothelin-expressing mesothelioma, ovarian, and pancreatic cancers. Clin Cancer Res. 2007;13:5144-5149. (Pubitemid 47502082)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.17
, pp. 5144-5149
-
-
Hassan, R.1
Bullock, S.2
Premkumar, A.3
Kreitman, R.J.4
Kindler, H.5
Willingham, M.C.6
Pastan, I.7
-
57
-
-
3242698655
-
Phase i study of LMB-9 (B3(dsFv)PE38), a recombinant disulfide stabilized anti-Lewis y immunotoxin administered by continuous infusion
-
abstr 736
-
Hausner PF, Karp JE, Edelma NL, et al. Phase I study of LMB-9 (B3(dsFv)PE38), a recombinant disulfide stabilized anti-Lewis Y immunotoxin administered by continuous infusion. Proc Am Soc Clin Oncol. 2003:abstr 736.
-
(2003)
Proc Am Soc Clin Oncol
-
-
Hausner, P.F.1
Karp, J.E.2
Edelma, N.L.3
-
58
-
-
1642494793
-
Pretreatment with Rituximab Does Not Inhibit the Human Immune Response against the Immunogenic Protein LMB-1
-
DOI 10.1158/1078-0432.CCR-1160-3
-
Hassan R, Williams-Gould J, Watson T, et al. Pretreatment with rituximab does not inhibit the human immune response against the immunogenic protein LMB-1. Clin Cancer Res. 2004;10:16-18. (Pubitemid 38114156)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.1
, pp. 16-18
-
-
Hassan, R.1
Williams-Gould, J.2
Watson, T.3
Pai-Scherf, L.4
Pastan, I.5
-
59
-
-
22144495793
-
A phase-1 trial of bexarotene and denileukin diftitox in patients with relapsed or refractory cutaneous T-cell lymphoma
-
DOI 10.1182/blood-2004-11-4570
-
Foss F, Demierre MF, DiVenuti G. A phase-1 trial of bexarotene and denileukin diftitox in patients with relapsed or refractory cutaneous T-cell lymphoma. Blood. 2005;106: 454-457. (Pubitemid 40981237)
-
(2005)
Blood
, vol.106
, Issue.2
, pp. 454-457
-
-
Foss, F.1
Demierre, M.F.2
DiVenuti, G.3
-
60
-
-
37149001827
-
Phase II study of denileukin diftitox for previously treated indolent non-Hodgkin lymphoma: Final results of E1497
-
DOI 10.1080/10428190701694186, PII 783033618
-
Kuzel TM, Li S, Eklund J, et al. Phase II study of denileukin diftitox for previously treated indolent non-Hodgkin lymphoma: final results of E1497. Leuk Lymphoma. 2007; 48:2397-2402. (Pubitemid 350253471)
-
(2007)
Leukemia and Lymphoma
, vol.48
, Issue.12
, pp. 2397-2402
-
-
Kuzel, T.M.1
Li, S.2
Eklund, J.3
Foss, F.4
Gascoyne, R.5
Abramson, N.6
Schwerkoske, J.F.7
Weller, E.8
Horning, S.J.9
-
61
-
-
67749142288
-
A Phase II trial of Denileukin Diftitox in patients with previously treated advanced non-small cell lung cancer
-
Gerena-Lewis M, Crawford J, Bonomi P, et al. A Phase II trial of Denileukin Diftitox in patients with previously treated advanced non-small cell lung cancer. Am J Clin Oncol. 2009;32:269-273.
-
(2009)
Am J Clin Oncol
, vol.32
, pp. 269-273
-
-
Gerena-Lewis, M.1
Crawford, J.2
Bonomi, P.3
-
62
-
-
77951650540
-
Phase III placebocontrolled trial of denileukin diftitox for patients with cutaneous T-cell lymphoma
-
Prince HM, Duvic M, Martin A, et al. Phase III placebocontrolled trial of denileukin diftitox for patients with cutaneous T-cell lymphoma. J Clin Oncol. 2010;28:1870-1877.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1870-1877
-
-
Prince, H.M.1
Duvic, M.2
Martin, A.3
-
63
-
-
79960501416
-
Novel immunotherapeutic agents and small molecule antagonists of signalling kinases for the treatment of metastatic melanoma
-
Natarajan N, Telang S, Miller D, et al. Novel immunotherapeutic agents and small molecule antagonists of signalling kinases for the treatment of metastatic melanoma. Drugs. 2011;71:1233-1250.
-
(2011)
Drugs
, vol.71
, pp. 1233-1250
-
-
Natarajan, N.1
Telang, S.2
Miller, D.3
-
64
-
-
78149246546
-
Pharmacology of anti-CD3 diphtheria immunotoxin in CD3 positive T-cell lymphoma trials
-
Woo JH, Lee YJ, Neville DM, et al. Pharmacology of anti-CD3 diphtheria immunotoxin in CD3 positive T-cell lymphoma trials. Methods Mol Biol. 2010;651:157-175.
-
(2010)
Methods Mol Biol
, vol.651
, pp. 157-175
-
-
Woo, J.H.1
Lee, Y.J.2
Neville, D.M.3
-
65
-
-
70249101823
-
Phase i dose escalation, pharmacokinetic and pharmacodynamic study of naptumomab estafenatox alone in patients with advanced cancer and with docetaxel in patients with advanced nonsmall-cell lung cancer
-
Borghaei H, Alpaugh K, Hedlund G, et al. Phase I dose escalation, pharmacokinetic and pharmacodynamic study of naptumomab estafenatox alone in patients with advanced cancer and with docetaxel in patients with advanced nonsmall-cell lung cancer. J Clin Oncol. 2009;27:4116-4123.
-
(2009)
J Clin Oncol
, vol.27
, pp. 4116-4123
-
-
Borghaei, H.1
Alpaugh, K.2
Hedlund, G.3
-
67
-
-
2142829523
-
A dominant linear B-cell epitope of ricin A-chain is the target of a neutralizing antibody response in Hodgkin's lymphoma patients treated with an anti-CD25 immunotoxin
-
DOI 10.1111/j.1365-2249.2004.02442.x
-
Castelletti D, Fracasso G, Righetti S, et al. A dominant linear B-cell epitope of ricin A-chain is the target of a neutralizing antibody response in Hodgkin's lymphoma patients treated with an anti-CD25 immunotoxin. Clin Exp Immunol. 2004; 136:365-372. (Pubitemid 38543458)
-
(2004)
Clinical and Experimental Immunology
, vol.136
, Issue.2
, pp. 365-372
-
-
Castelletti, D.1
Fracasso, G.2
Righetti, S.3
Tridente, G.4
Schnell, R.5
Engert, A.6
Colombatti, M.7
-
68
-
-
0013379930
-
Clinical evaluation of ricin A-chain immunotoxins in patients with Hodgkin's lymphoma
-
DOI 10.1093/annonc/mdg209
-
Schnell R, Borchmann P, Staak JO, et al. Clinical evaluation of ricin A-chain immunotoxins in patients with Hodgkin's lymphoma. Ann Oncol. 2003;14:729-736. (Pubitemid 36621773)
-
(2003)
Annals of Oncology
, vol.14
, Issue.5
, pp. 729-736
-
-
Schnell, R.1
Borchmann, P.2
Staak, J.O.3
Schindler, J.4
Ghetie, V.5
Vitetta, E.S.6
Engert, A.7
-
69
-
-
0033978156
-
Treatment of refractory Hodgkin's lymphoma patients with an anti-CD25 ricin A-chain immunotoxin
-
Schnell R, Vitetta E, Schindler J, et al. Treatment of refractory Hodgkin's lymphoma patients with an anti-CD25 ricin A-chain immunotoxin. Leukemia. 2000;14: 129-135. (Pubitemid 30068384)
-
(2000)
Leukemia
, vol.14
, Issue.1
, pp. 129-135
-
-
Schnell, R.1
Vitetta, E.2
Schindler, J.3
Borchmann, P.4
Barth, S.5
Ghetie, V.6
Hell, K.7
Drillich, S.8
Diehl, V.9
Engert, A.10
-
70
-
-
0029056665
-
Continuous infusion of the anti-CD22 immunotoxin IgGRFB4-SMPT-dgA in patients with B-cell lymphoma: A phase i study
-
Sausville EA, Headlee D, Stetler-Stevenson M, et al. Continuous infusion of the anti-CD22 immunotoxin IgGRFB4-SMPT-dgA in patients with B-cell lymphoma: a phase I study. Blood. 1995;85:3457-3465.
-
(1995)
Blood
, vol.85
, pp. 3457-3465
-
-
Sausville, E.A.1
Headlee, D.2
Stetler-Stevenson, M.3
-
73
-
-
77955312203
-
Antibody-drug conjugates: Targeted drug delivery for cancer
-
Alley SC, Okeley NM, Senter PD. Antibody-drug conjugates: targeted drug delivery for cancer. Curr Opin Chem Biol. 2010;14:529-537.
-
(2010)
Curr Opin Chem Biol
, vol.14
, pp. 529-537
-
-
Alley, S.C.1
Okeley, N.M.2
Senter, P.D.3
-
74
-
-
84857235735
-
-
Food and Drug Administration Accessed September 26, 2011
-
Food and Drug Administration. Brentuximab Vedotin [FDA Web site]. 2011. Available at: http://www.fda.gov/AboutFDA/CentersOffices/CDER/ucm268969.htm, Accessed September 26, 2011.
-
(2011)
Brentuximab Vedotin [FDA Web Site]
-
-
-
75
-
-
78651447411
-
A Phase II study of trastuzumab-DM1 (T-DM1), a Novel HER2 antibody-drug conjugate, in patients with HER2+ Metastatic breast cancer who were previously treated with an anthracycline, a taxane, capecitabine, lapatinib, and trastuzumab
-
Abstract 710
-
Krop I, Lo Russo P, Miller KD, et al, A Phase II Study of Trastuzumab-DM1 (T-DM1), a Novel HER2 Antibody-Drug Conjugate, in Patients with HER2+ Metastatic Breast Cancer who were Previously Treated with an Anthracycline, a Taxane, Capecitabine, Lapatinib, and Trastuzumab. 32nd Annual San Antonio Breast Cancer Symposium. 2009. Abstract 710.
-
(2009)
32nd Annual San Antonio Breast Cancer Symposium
-
-
Krop, I.1
Lo Russo, P.2
Miller, K.D.3
-
76
-
-
65249180124
-
Combining milatuzumab with bortezomib, doxorubicin, or dexamethasone improves responses in multiple myeloma cell lines
-
Stein R, Smith MR, Chen S, et al. Combining milatuzumab with bortezomib, doxorubicin, or dexamethasone improves responses in multiple myeloma cell lines. Clin Cancer Res. 2009;15:2808-2817.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2808-2817
-
-
Stein, R.1
Smith, M.R.2
Chen, S.3
-
77
-
-
79952992903
-
Immunoconjugates against solid tumors: Mind the gap
-
Ricart AD. Immunoconjugates against solid tumors: mind the gap. Clin Pharmacol Ther. 2011;89:513-523.
-
(2011)
Clin Pharmacol Ther
, vol.89
, pp. 513-523
-
-
Ricart, A.D.1
-
78
-
-
0033870271
-
Oncotic pressure in solid tumors is elevated
-
Stohrer M, Boucher Y, Stangassinger M, et al. Oncotic pressure in solid tumors is elevated. Cancer Res. 2000;60: 4251-4255. (Pubitemid 30636613)
-
(2000)
Cancer Research
, vol.60
, Issue.15
, pp. 4251-4255
-
-
Stohrer, M.1
Boucher, Y.2
Stangassinger, M.3
Jain, R.K.4
-
79
-
-
0026531995
-
The macroscopic and microscopic pharmacology of monoclonal antibodies
-
Weinstein JN, van Osdol W. The macroscopic and microscopic pharmacology of monoclonal antibodies. Int J Immunopharmacol. 1992;14:457-463.
-
(1992)
Int J Immunopharmacol
, vol.14
, pp. 457-463
-
-
Weinstein, J.N.1
Van Osdol, W.2
-
81
-
-
70349083423
-
The pharmacologic basis for antibody-auristatin conjugate activity
-
Alley SC, Zhang X, Okeley NM, et al. The pharmacologic basis for antibody-auristatin conjugate activity. J Pharmacol Exp Ther. 2009;330:932-938.
-
(2009)
J Pharmacol Exp Ther
, vol.330
, pp. 932-938
-
-
Alley, S.C.1
Zhang, X.2
Okeley, N.M.3
-
82
-
-
4444290767
-
The radiation biology of radioimmunotherapy
-
DOI 10.1097/00006231-200309000-00002
-
Dixon KL. The radiation biology of radioimmunotherapy. Nucl Med Commun. 2003;24:951-957. (Pubitemid 39625408)
-
(2003)
Nuclear Medicine Communications
, vol.24
, Issue.9
, pp. 951-957
-
-
Dixon, K.L.1
-
83
-
-
30744447697
-
Antibody-guided radiation therapy of cancer
-
DOI 10.1007/s10555-005-6195-z
-
Koppe MJ, Postema EJ, Aarts F, et al. Antibody-guided radiation therapy of cancer. Cancer Metastasis Rev. 2005; 24:539-567. (Pubitemid 43097000)
-
(2005)
Cancer and Metastasis Reviews
, vol.24
, Issue.4
, pp. 539-567
-
-
Koppe, M.J.1
Postema, E.J.2
Aarts, F.3
Oyen, W.J.G.4
Bleichrodt, R.P.5
Boerman, O.C.6
-
84
-
-
0034763077
-
Radioimmunotherapy of B-cell non-Hodgkin's lymphoma
-
DOI 10.1007/s002590100570
-
Postema EJ, Boerman OC, Oyen WJ, et al. Radioimmunotherapy of B-cell non-Hodgkin's lymphoma. Eur J Nucl Med. 2001;28:1725-1735. (Pubitemid 33036117)
-
(2001)
European Journal of Nuclear Medicine
, vol.28
, Issue.11
, pp. 1725-1735
-
-
Postema, E.J.1
Boerman, O.C.2
Oyen, W.J.3
Raemaekers, J.M.4
Corstens, F.H.5
-
85
-
-
15944409978
-
Radioimmunotherapy and colorectal cancer
-
DOI 10.1002/bjs.4936
-
Koppe MJ, Bleichrodt RP, Oyen WJ, et al. Radioimmunotherapy and colorectal cancer. Br J Surg. 2005;92: 264-276. (Pubitemid 40445588)
-
(2005)
British Journal of Surgery
, vol.92
, Issue.3
, pp. 264-276
-
-
Koppe, M.J.1
Bleichrodt, R.P.2
Oyen, W.J.G.3
Boerman, O.C.4
-
86
-
-
78650868824
-
Radioimmunotherapy of solid tumors: Searching for the right target
-
Song H, Sgouros G. Radioimmunotherapy of solid tumors: searching for the right target. Curr Drug Deliv. 2011;8:26-44.
-
(2011)
Curr Drug Deliv
, vol.8
, pp. 26-44
-
-
Song, H.1
Sgouros, G.2
-
88
-
-
1642535523
-
Reducing the Immune Response to Immunotoxin
-
DOI 10.1158/1078-0432.CCR-1216-3
-
Frankel AE. Reducing the immune response to immunotoxin. Clin Cancer Res. 2004;10:13-15. (Pubitemid 38114155)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.1
, pp. 13-15
-
-
Frankel, A.E.1
-
89
-
-
0034895032
-
Antibody response to DT-GM, a novel fusion toxin consisting of a truncated diphtheria toxin (DT) linked to human granulocyte-macrophage colony stimulating factor (GM), during a phase i trial of patients with relapsed or refractory acute myeloid leukemia
-
Hall PD, Virella G, Willoughby T, et al. Antibody response to DT-GM, a novel fusion toxin consisting of a truncated diphtheria toxin (DT) linked to human granulocyte-macrophage colony stimulating factor (GM), during a phase I trial of patients with relapsed or refractory acute myeloid leukemia. Clin Immunol. 2001;100:191-197.
-
(2001)
Clin Immunol
, vol.100
, pp. 191-197
-
-
Hall, P.D.1
Virella, G.2
Willoughby, T.3
-
90
-
-
0023465986
-
Humoral immune response to a ricin a chain immunotoxin in patients with metastatic melanoma
-
Hertler AA, Spitler LE, Frankel AE. Humoral immune response to a ricin a chain immunotoxin in patients with metastatic melanoma. Cancer Drug Deliv. 1987;4:245-253.
-
(1987)
Cancer Drug Deliv
, vol.4
, pp. 245-253
-
-
Hertler, A.A.1
Spitler, L.E.2
Frankel, A.E.3
-
91
-
-
67650678448
-
Humanized immunotoxins: A new generation of immunotoxins for targeted cancer therapy
-
Mathew M, Verma RS. Humanized immunotoxins: a new generation of immunotoxins for targeted cancer therapy. Cancer Sci. 2009;100:1359-1365.
-
(2009)
Cancer Sci
, vol.100
, pp. 1359-1365
-
-
Mathew, M.1
Verma, R.S.2
-
94
-
-
0033125226
-
Antitumor necrosis factor therapy for inflammatory bowel disease: A review of agents, pharmacology, clinical results, and safety
-
Sandborn WJ, Hanauer SB. Antitumor necrosis factor therapy for inflammatory bowel disease: a review of agents, pharmacology, clinical results, and safety. Inflamm Bowel Dis. 1999;5:119-133.
-
(1999)
Inflamm Bowel Dis
, vol.5
, pp. 119-133
-
-
Sandborn, W.J.1
Hanauer, S.B.2
-
95
-
-
38949192547
-
Targeted cancer therapy: Conferring specificity to cytotoxic drugs
-
Chari RV. Targeted cancer therapy: conferring specificity to cytotoxic drugs. Acc Chem Res. 2008;41:98-107.
-
(2008)
Acc Chem Res
, vol.41
, pp. 98-107
-
-
Chari, R.V.1
-
96
-
-
40949138516
-
Anti-CD20 monoclonal antibody therapy in multiple myeloma
-
DOI 10.1111/j.1365-2141.2008.07024.x
-
Kapoor P, Greipp PT, Morice WG, et al. Anti-CD20 monoclonal antibody therapy in multiple myeloma. Br J Haematol. 2008;141:135-148. (Pubitemid 351406208)
-
(2008)
British Journal of Haematology
, vol.141
, Issue.2
, pp. 135-148
-
-
Kapoor, P.1
Greipp, P.T.2
Morice, W.G.3
Rajkumar, S.V.4
Witzig, T.E.5
Greipp, P.R.6
-
98
-
-
0344958862
-
Identification of the gene variations in human CD22
-
DOI 10.1007/s002510050494
-
Hatta Y, Tsuchiya N, Matsushita M, et al. Identification of the gene variations in human CD22. Immunogenetics. 1999;49:280-286. (Pubitemid 29119037)
-
(1999)
Immunogenetics
, vol.49
, Issue.4
, pp. 280-286
-
-
Hatta, Y.1
Tsuchiya, N.2
Matsushita, M.3
Shiota, M.4
Hagiwara, K.5
Tokunaga, K.6
-
99
-
-
0034773992
-
The EGFR family and its ligands in human cancer: Signalling mechanisms and therapeutic opportunities
-
PII S0959804901002301
-
Yarden Y. The EGFR family and its ligands in human cancer: signalling mechanisms and therapeutic opportunities. Eur J Cancer. 2001;37(Suppl 4):S3-S8. (Pubitemid 32938123)
-
(2001)
European Journal of Cancer
, vol.37
, Issue.SUPPL. 4
-
-
Yarden, Y.1
-
101
-
-
80055001527
-
Her-2/neu gene amplification and over-expression in stomach and esophageal adenocarcinoma: From pathology to treatment
-
[Epub ahead of print]
-
Maresch J, Schoppmann SF, Thallinger CM, et al. Her-2/neu gene amplification and over-expression in stomach and esophageal adenocarcinoma: from pathology to treatment. Crit Rev Oncol Hematol. 2011. [Epub ahead of print].
-
(2011)
Crit Rev Oncol Hematol
-
-
Maresch, J.1
Schoppmann, S.F.2
Thallinger, C.M.3
-
102
-
-
67649335394
-
Advances in preclinical small molecules for the treatment of NSCLC
-
Zhang Q, Feng W, Zhou H, et al. Advances in preclinical small molecules for the treatment of NSCLC. Expert Opin Ther Pat. 2009;19:731-751.
-
(2009)
Expert Opin Ther Pat
, vol.19
, pp. 731-751
-
-
Zhang, Q.1
Feng, W.2
Zhou, H.3
-
103
-
-
0033514509
-
1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/akt pathway
-
DOI 10.1073/pnas.96.5.2110
-
Ramaswamy S, Nakamura N, Vazquez F, et al. Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway. Proc Natl Acad Sci USA. 1999;96:2110-2115. (Pubitemid 29117876)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.5
, pp. 2110-2115
-
-
Ramaswamy, S.1
Nakamura, N.2
Vazquez, F.3
Batt, D.B.4
Perera, S.5
Roberts, T.M.6
Sellers, W.R.7
-
104
-
-
0036841293
-
2/M cell cycle checkpoint induced by DNA damage
-
DOI 10.1128/MCB.22.22.7831-7841.2002
-
Kandel ES, Skeen J, Majewski N, et al. Activation of Akt/protein kinase B overcomes a G(2)/m cell cycle checkpoint induced by DNA damage. Mol Cell Biol. 2002;22:7831-7841. (Pubitemid 35217294)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.22
, pp. 7831-7841
-
-
Kandel, E.S.1
Skeen, J.2
Majewski, N.3
Di Cristofano, A.4
Pandolfi, P.P.5
Feliciano, C.S.6
Gartel, A.7
Hay, N.8
-
105
-
-
33644785936
-
Akt1 in endothelial cell and angiogenesis
-
Somanath PR, Razorenova OV, Chen J, et al. Akt1 in endothelial cell and angiogenesis. Cell Cycle. 2006;5:512-518. (Pubitemid 43340529)
-
(2006)
Cell Cycle
, vol.5
, Issue.5
, pp. 512-518
-
-
Somanath, P.R.1
Razorenova, O.V.2
Chen, J.3
Byzova, T.V.4
-
106
-
-
0030500450
-
New perspectives in clinical oncology from angiogenesis research
-
Folkman J. New perspectives in clinical oncology from angiogenesis research. Eur J Cancer. 1996;32A:2534-2539.
-
(1996)
Eur J Cancer
, vol.32 A
, pp. 2534-2539
-
-
Folkman, J.1
-
107
-
-
0031026481
-
Tumor infarction in mice by antibody-directed targeting of tissue factor to tumor vasculature
-
DOI 10.1126/science.275.5299.547
-
Huang X, Molema G, King S, et al. Tumor infarction in mice by antibody-directed targeting of tissue factor to tumor vasculature. Science. 1997;275:547-550. (Pubitemid 27051913)
-
(1997)
Science
, vol.275
, Issue.5299
, pp. 547-550
-
-
Huang, X.1
Molema, G.2
King, S.3
Watkins, L.4
Edgington, T.S.5
Thorpe, P.E.6
-
108
-
-
0032532656
-
Infarction of solid Hodgkin's tumors in mice by antibody-directed targeting of tissue factor to tumor vasculature
-
Ran S, Gao B, Duffy S, et al. Infarction of solid Hodgkin's tumors in mice by antibody-directed targeting of tissue factor to tumor vasculature. Cancer Res. 1998;58:4646-4653. (Pubitemid 28480630)
-
(1998)
Cancer Research
, vol.58
, Issue.20
, pp. 4646-4653
-
-
Ran, S.1
Gao, B.2
Duffy, S.3
Watkins, L.4
Rote, N.5
Thorpe, P.E.6
-
109
-
-
0032971818
-
Induction of lasting complete regression of preformed distinct solid tumors by targeting the tumor vasculature using two new anti-endoglin monoclonal antibodies
-
Matsuno F, Haruta Y, Kondo M, et al. Induction of lasting complete regression of preformed distinct solid tumors by targeting the tumor vasculature using two new anti-endoglin monoclonal antibodies. Clin Cancer Res. 1999;5:371-382. (Pubitemid 29085191)
-
(1999)
Clinical Cancer Research
, vol.5
, Issue.2
, pp. 371-382
-
-
Matsuno, F.1
Haruta, Y.2
Kondo, M.3
Tsai, H.4
Barcos, M.5
Seon, B.K.6
-
110
-
-
0031564123
-
Targeting the tumor vasculature: Inhibition of tumor growth by a vascular endothelial growth factor-toxin conjugate
-
Olson TA, Mohanraj D, Roy S, et al. Targeting the tumor vasculature: inhibition of tumor growth by a vascular endothelial growth factor-toxin conjugate. Int J Cancer. 1997;73:865-870. (Pubitemid 127483042)
-
(1997)
International Journal of Cancer
, vol.73
, Issue.6
, pp. 865-870
-
-
Olson, T.A.1
Mohanraj, D.2
Roy, S.3
Ramakrishnan, S.4
-
111
-
-
0032943892
-
Vascular endothelial growth factor chimeric toxin is highly active against endothelial cells
-
Arora N, Masood R, Zheng T, et al. Vascular endothelial growth factor chimeric toxin is highly active against endothelial cells. Cancer Res. 1999;59:183-188. (Pubitemid 29062976)
-
(1999)
Cancer Research
, vol.59
, Issue.1
, pp. 183-188
-
-
Arora, N.1
Masood, R.2
Zheng, T.3
Cai, J.4
Smith, D.L.5
Gill, P.S.6
-
112
-
-
0032535999
-
Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model
-
DOI 10.1126/science.279.5349.377
-
Arap W, Pasqualini R, Ruoslahti E. Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model. Science. 1998;279:377-380. (Pubitemid 28063372)
-
(1998)
Science
, vol.279
, Issue.5349
, pp. 377-380
-
-
Arap, W.1
Pasqualini, R.2
Ruoslahti, E.3
-
113
-
-
0037189380
-
Tumor regression by targeted gene delivery to the neovasculature
-
DOI 10.1126/science.1070200
-
Hood JD, Bednarski M, Frausto R, et al. Tumor regression by targeted gene delivery to the neovasculature. Science. 2002;296:2404-2407. (Pubitemid 34734217)
-
(2002)
Science
, vol.296
, Issue.5577
, pp. 2404-2407
-
-
Hood, J.D.1
Bednarski, M.2
Frausto, R.3
Guccione, S.4
Reisfeld, R.A.5
Xiang, R.6
Cheresh, D.A.7
-
114
-
-
0032580493
-
Delivery of molecular and cellular medicine to solid tumors
-
DOI 10.1016/S0168-3659(97)00237-X, PII S016836599700237X
-
Jain RK. Delivery of molecular and cellular medicine to solid tumors. J Control Release. 1998;53:49-67. (Pubitemid 28218689)
-
(1998)
Journal of Controlled Release
, vol.53
, Issue.1-3
, pp. 49-67
-
-
Jain, R.K.1
-
115
-
-
0037264969
-
Therapeutic antibodies for human diseases at the dawn of the twenty-first century
-
DOI 10.1038/nrd984
-
Brekke OH, Sandlie I. Therapeutic antibodies for human diseases at the dawn of the twenty-first century. Nat Rev Drug Discov. 2003;2:52-62. (Pubitemid 37361624)
-
(2003)
Nature Reviews Drug Discovery
, vol.2
, Issue.1
, pp. 52-62
-
-
Brekke, O.H.1
Sandlie, I.2
-
116
-
-
68349117269
-
Single domain antibodies: Promising experimental and therapeutic tools in infection and immunity
-
Wesolowski J, Alzogaray V, Reyelt J, et al. Single domain antibodies: promising experimental and therapeutic tools in infection and immunity. Med Microbiol Immunol. 2009;198: 157-174.
-
(2009)
Med Microbiol Immunol
, vol.198
, pp. 157-174
-
-
Wesolowski, J.1
Alzogaray, V.2
Reyelt, J.3
-
117
-
-
77953653252
-
Antibody fragments: Hope and hype
-
Nelson AL. Antibody fragments: hope and hype. MAbs. 2010;2:77-83.
-
(2010)
MAbs
, vol.2
, pp. 77-83
-
-
Nelson, A.L.1
-
118
-
-
64349107630
-
Development trends for therapeutic antibody fragments
-
Nelson AL, Reichert JM. Development trends for therapeutic antibody fragments. Nat Biotechnol. 2009;27:331-337.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 331-337
-
-
Nelson, A.L.1
Reichert, J.M.2
-
119
-
-
4043152053
-
Peptibodies: The new cool technology
-
DOI 10.1016/S1359-6446(04)03216-7, PII S1359644604032167
-
Sutherland S. Peptibodies: the new cool technology. Drug Discov Today. 2004;9:683. (Pubitemid 39070275)
-
(2004)
Drug Discovery Today
, vol.9
, Issue.16
, pp. 683
-
-
Sutherland, S.1
-
120
-
-
0037235949
-
Engineered antibodies
-
DOI 10.1038/nm0103-129
-
Hudson PJ, Souriau C. Engineered antibodies. Nat Med. 2003;9:129-134. (Pubitemid 36098274)
-
(2003)
Nature Medicine
, vol.9
, Issue.1
, pp. 129-134
-
-
Hudson, P.J.1
Souriau, C.2
-
121
-
-
23044494423
-
Demonstration of an in vivo generated sub-picomolar affinity fully human monoclonal antibody to interleukin-8
-
DOI 10.1016/j.bbrc.2005.07.002, PII S0006291X05014452
-
Rathanaswami P, Roalstad S, Roskos L, et al. Demonstration of an in vivo generated sub-picomolar affinity fully human monoclonal antibody to interleukin-8. Biochem Biophys Res Commun. 2005;334:1004-1013. (Pubitemid 41074676)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.334
, Issue.4
, pp. 1004-1013
-
-
Rathanaswami, P.1
Roalstad, S.2
Roskos, L.3
Su, Q.J.4
Lackie, S.5
Babcook, J.6
-
122
-
-
33645500289
-
Antibodymaytansinoid conjugates are activated in targeted cancer cells by lysosomal degradation and linker-dependent intracellular processing
-
Erickson HK, Park PU, Widdison WC, et al. Antibodymaytansinoid conjugates are activated in targeted cancer cells by lysosomal degradation and linker-dependent intracellular processing. Cancer Res. 2006;66:4426-4433.
-
(2006)
Cancer Res
, vol.66
, pp. 4426-4433
-
-
Erickson, H.K.1
Park, P.U.2
Widdison, W.C.3
-
123
-
-
74949107560
-
Antibody-drug conjugates: Linking cytotoxic payloads to monoclonal antibodies
-
Ducry L, Stump B. Antibody-drug conjugates: linking cytotoxic payloads to monoclonal antibodies. Bioconjug Chem. 2010;21:5-13.
-
(2010)
Bioconjug Chem
, vol.21
, pp. 5-13
-
-
Ducry, L.1
Stump, B.2
-
124
-
-
0034651996
-
Unraveling the role of proteases in cancer
-
DOI 10.1016/S0009-8981(99)00224-7, PII S0009898199002247
-
Koblinski JE, Ahram M, Sloane BF. Unraveling the role of proteases in cancer. Clin Chim Acta. 2000;291:113-135. (Pubitemid 30089760)
-
(2000)
Clinica Chimica Acta
, vol.291
, Issue.2
, pp. 113-135
-
-
Koblinski, J.E.1
Ahram, M.2
Sloane, B.F.3
-
125
-
-
49449087300
-
Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index
-
Junutula JR, Raab H, Clark S, et al. Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index. Nat Biotechnol. 2008;26:925-932.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 925-932
-
-
Junutula, J.R.1
Raab, H.2
Clark, S.3
-
126
-
-
65549151884
-
Antibodydrug conjugates for the treatment of non-Hodgkin's lymphoma: Target and linker-drug selection
-
Polson AG, Calemine-Fenaux J, Chan P, et al. Antibodydrug conjugates for the treatment of non-Hodgkin's lymphoma: target and linker-drug selection. Cancer Res. 2009;69: 2358-2364.
-
(2009)
Cancer Res
, vol.69
, pp. 2358-2364
-
-
Polson, A.G.1
Calemine-Fenaux, J.2
Chan, P.3
-
127
-
-
34848861947
-
The dock and lock method: A novel platform technology for building multivalent, multifunctional structures of defined composition with retained bioactivity
-
DOI 10.1158/1078-0432.CCR-07-1217
-
Chang CH, Rossi EA, Goldenberg DM. The dock and lock method: a novel platform technology for building multivalent, multifunctional structures of defined composition with retained bioactivity. Clin Cancer Res. 2007;13: 5586s-5591s. (Pubitemid 47510391)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.18
-
-
Chang, C.-H.1
Rossi, E.A.2
Goldenberg, D.M.3
-
128
-
-
47049095740
-
Bifunctional coupling agents for radiolabeling of biomolecules and target-specific delivery of metallic radionuclides
-
Liu S. Bifunctional coupling agents for radiolabeling of biomolecules and target-specific delivery of metallic radionuclides. Adv Drug Deliv Rev. 2008;60:1347-1370.
-
(2008)
Adv Drug Deliv Rev
, vol.60
, pp. 1347-1370
-
-
Liu, S.1
-
129
-
-
79960820705
-
Immunotoxins and anticancer drug conjugate assemblies: The role of the linkage between components
-
Dosio F, Brusa P, Cattel L. Immunotoxins and anticancer drug conjugate assemblies: the role of the linkage between components. Toxins. 2011;3:848-883.
-
(2011)
Toxins
, vol.3
, pp. 848-883
-
-
Dosio, F.1
Brusa, P.2
Cattel, L.3
-
130
-
-
77950224905
-
Antibodymaytansinoid conjugates designed to bypass multidrug resistance
-
Kovtun YV, Audette CA, Mayo MF, et al. Antibodymaytansinoid conjugates designed to bypass multidrug resistance. Cancer Res. 2010;70:2528-2537.
-
(2010)
Cancer Res
, vol.70
, pp. 2528-2537
-
-
Kovtun, Y.V.1
Audette, C.A.2
Mayo, M.F.3
-
131
-
-
0344082608
-
Progress in the development and acquisition of anticancer agents from marine sources
-
DOI 10.1093/annonc/mdg443
-
Amador ML, Jimeno J, Paz-Ares L, et al. Progress in the development and acquisition of anticancer agents from marine sources. Ann Oncol. 2003;14:1607-1615. (Pubitemid 37460970)
-
(2003)
Annals of Oncology
, vol.14
, Issue.11
, pp. 1607-1615
-
-
Amador, M.L.1
Jimeno, J.2
Paz-Ares, L.3
Cortes-Funes, H.4
Hidalgo, M.5
-
132
-
-
0042628147
-
Marine-derived anticancer agents in clinical trials
-
DOI 10.1517/eoid.12.8.1367.21768
-
Schwartsmann G, Da Rocha AB, Mattei J, et al. Marinederived anticancer agents in clinical trials. Expert Opin Investig Drugs. 2003;12:1367-1383. (Pubitemid 36957792)
-
(2003)
Expert Opinion on Investigational Drugs
, vol.12
, Issue.8
, pp. 1367-1383
-
-
Schwartsmann, G.1
Brondani Da Rocha, A.2
Mattei, J.3
Lopes, R.M.4
-
133
-
-
42249104716
-
Efficacy of selected natural products as therapeutic agents against cancer
-
DOI 10.1021/np0705716
-
Banerjee S, Wang Z, Mohammad M, et al. Efficacy of selected natural products as therapeutic agents against cancer. J Nat Prod. 2008;71:492-496. (Pubitemid 351549382)
-
(2008)
Journal of Natural Products
, vol.71
, Issue.3
, pp. 492-496
-
-
Banerjee, S.1
Wang, Z.2
Mohammad, M.3
Sarkar, F.H.4
Mohammad, R.M.5
-
134
-
-
10744222473
-
Development of potent monoclonal antibody auristatin conjugates for cancer therapy
-
DOI 10.1038/nbt832
-
Doronina SO, Toki BE, Torgov MY, et al. Development of potent monoclonal antibody auristatin conjugates for cancer therapy. Nat Biotechnol. 2003;21:778-784. (Pubitemid 36791396)
-
(2003)
Nature Biotechnology
, vol.21
, Issue.7
, pp. 778-784
-
-
Doronina, S.O.1
Toki, B.E.2
Torgov, M.Y.3
Mendelsohn, B.A.4
Cerveny, C.G.5
Chace, D.F.6
DeBlanc, R.L.7
Gearing, R.P.8
Bovee, T.D.9
Siegall, C.B.10
Francisco, J.A.11
Wahl, A.F.12
Meyer, D.L.13
Senter, P.D.14
-
135
-
-
9744243565
-
Efficient elimination of B-lineage lymphomas by anti-CD20-auristatin conjugates
-
DOI 10.1158/1078-0432.CCR-04-1028
-
Law CL, Cerveny CG, Gordon KA, et al. Efficient elimination of B-lineage lymphomas by anti-CD20-auristatin conjugates. Clin Cancer Res. 2004;10:7842-7851. (Pubitemid 39587522)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.23
, pp. 7842-7851
-
-
Law, C.-L.1
Cerveny, C.G.2
Gordon, K.A.3
Klussman, K.4
Mixan, B.J.5
Chace, D.F.6
Meyer, D.L.7
Doronina, S.O.8
Siegall, C.B.9
Francisco, J.A.10
Senter, P.D.11
Wahl, A.F.12
-
136
-
-
0024322591
-
Calicheamicins, a novel family of antitumor antibiotics. 3: Isolation, purification and characterization of calicheamicins beta 1Br, gamma 1Br, alpha 2I, alpha 3I, beta 1I, gamma 1I and delta 1I
-
Lee MD, Manning JK, Williams DR, et al. Calicheamicins, a novel family of antitumor antibiotics. 3: isolation, purification and characterization of calicheamicins beta 1Br, gamma 1Br, alpha 2I, alpha 3I, beta 1I, gamma 1I and delta 1I. J Antibiot (Tokyo). 1989;42:1070-1087.
-
(1989)
J Antibiot (Tokyo)
, vol.42
, pp. 1070-1087
-
-
Lee, M.D.1
Manning, J.K.2
Williams, D.R.3
-
137
-
-
0023820894
-
Calicheamicin gamma 1I: An antitumor antibiotic that cleaves double-stranded DNA site specifically
-
Zein N, Sinha AM, McGahren WJ, et al. Calicheamicin gamma 1I: an antitumor antibiotic that cleaves double-stranded DNA site specifically. Science. 1988;240: 1198-1201.
-
(1988)
Science
, vol.240
, pp. 1198-1201
-
-
Zein, N.1
Sinha, A.M.2
McGahren, W.J.3
-
138
-
-
0025336716
-
Structure/function analysis of interleukin-2-toxin (DAB486-IL-2): Fragment B sequences required for the delivery of fragment A to the cytosol of target cells
-
Williams DP, Snider CE, Strom TB, et al. Structure/function analysis of interleukin-2-toxin (DAB486-IL-2): fragment B sequences required for the delivery of fragment A to the cytosol of target cells. J Biol Chem. 1990;265:11885-11889.
-
(1990)
J Biol Chem
, vol.265
, pp. 11885-11889
-
-
Williams, D.P.1
Snider, C.E.2
Strom, T.B.3
-
139
-
-
0034468310
-
Principles of radioimmunotherapy for hematologists and oncologists
-
Press OW, Rasey J. Principles of radioimmunotherapy for hematologists and oncologists. Semin Oncol. 2000;27: 62-73. (Pubitemid 32164597)
-
(2000)
Seminars in Oncology
, vol.27
, Issue.6 SUPPL. 12
, pp. 62-73
-
-
Press, O.W.1
Rasey, J.2
-
140
-
-
0036682214
-
Treatment with ibritumomab tiuxetan radioimmunotherapy in patients with rituximab-refractory follicular non-Hodgkin's lymphoma
-
DOI 10.1200/JCO.2002.11.017
-
Witzig TE, Flinn IW, Gordon LI, et al. Treatment with ibritumomab tiuxetan radioimmunotherapy in patients with rituximab-refractory follicular non-Hodgkin's lymphoma. J Clin Oncol. 2002;20:3262-3269. (Pubitemid 34831524)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.15
, pp. 3262-3269
-
-
Witzig, T.E.1
Flinn, I.W.2
Gordon, L.I.3
Emmanouilides, C.4
Czuczman, M.S.5
Saleh, M.N.6
Cripe, L.7
Wiseman, G.8
Olejnik, T.9
Multani, P.S.10
White, C.A.11
-
141
-
-
0025827668
-
Choosing the right radionuclide and antibody for intraperitoneal radioimmunotherapy
-
Larson SM. Choosing the right radionuclide and antibody for intraperitoneal radioimmunotherapy. J Natl Cancer Inst. 1991;83:1602-1604.
-
(1991)
J Natl Cancer Inst
, vol.83
, pp. 1602-1604
-
-
Larson, S.M.1
-
142
-
-
0032848896
-
Radioimmunotherapy for lymphoma
-
DOI 10.1097/00001622-199909000-00009
-
Zelenetz AD. Radioimmunotherapy for lymphoma. Curr Opin Oncol. 1999;11:375-380. (Pubitemid 29410880)
-
(1999)
Current Opinion in Oncology
, vol.11
, Issue.5
, pp. 375-380
-
-
Zelenetz, A.D.1
-
143
-
-
80052665722
-
Prostate-specific membrane antigen-based therapeutics
-
Akhtar NH, Pail O, Saran A, et al. Prostate-specific membrane antigen-based therapeutics. Advances in Urology. 2012;2012:973820.
-
(2012)
Advances in Urology
, vol.2012
, pp. 973820
-
-
Akhtar, N.H.1
Pail, O.2
Saran, A.3
-
144
-
-
68949213822
-
Antibody-directed enzyme prodrug therapy: A promising approach for a selective treatment of cancer based on prodrugs and monoclonal antibodies
-
Tietze LF, Krewer B. Antibody-directed enzyme prodrug therapy: a promising approach for a selective treatment of cancer based on prodrugs and monoclonal antibodies. Chem Biol Drug Des. 2009;74:205-211.
-
(2009)
Chem Biol Drug des
, vol.74
, pp. 205-211
-
-
Tietze, L.F.1
Krewer, B.2
-
145
-
-
80052972715
-
A humanized immunoenzyme with enhanced activity for glucuronide prodrug activation in the tumor microenvironment
-
Chen KC, Wu SY, Leu YL, et al. A humanized immunoenzyme with enhanced activity for glucuronide prodrug activation in the tumor microenvironment. Bioconjug Chem. 2011; 22:938-948.
-
(2011)
Bioconjug Chem
, vol.22
, pp. 938-948
-
-
Chen, K.C.1
Wu, S.Y.2
Leu, Y.L.3
-
146
-
-
74349104707
-
Characterization of an engineered human purine nucleoside phosphorylase fused to an anti-her2/neu single chain Fv for use in ADEPT
-
Afshar S, Olafsen T, Wu AM, et al. Characterization of an engineered human purine nucleoside phosphorylase fused to an anti-her2/neu single chain Fv for use in ADEPT. J Exp Clin Cancer Res. 2009;28:147.
-
(2009)
J Exp Clin Cancer Res
, vol.28
, pp. 147
-
-
Afshar, S.1
Olafsen, T.2
Wu, A.M.3
-
147
-
-
14644396096
-
Nanomedicine: Current status and future prospects
-
DOI 10.1096/fj.04-2747rev
-
Moghimi SM, Hunter AC, Murray JC. Nanomedicine: current status and future prospects. FASEB J. 2005;19: 311-330. (Pubitemid 40316520)
-
(2005)
FASEB Journal
, vol.19
, Issue.3
, pp. 311-330
-
-
Moghimi, S.M.1
Hunter, A.C.2
Murray, J.C.3
-
148
-
-
79953792313
-
Nanomedicine: A new frontier in cancer therapeutics
-
Lee PY, Wong KK. Nanomedicine: a new frontier in cancer therapeutics. Curr Drug Deliv. 2011;8:245-253.
-
(2011)
Curr Drug Deliv
, vol.8
, pp. 245-253
-
-
Lee, P.Y.1
Wong, K.K.2
-
149
-
-
77951888124
-
Nanotechnology applications in surgical oncology
-
Singhal S, Nie S, Wang MD. Nanotechnology applications in surgical oncology. Annu Rev Med. 2010;61:359-373.
-
(2010)
Annu Rev Med
, vol.61
, pp. 359-373
-
-
Singhal, S.1
Nie, S.2
Wang, M.D.3
-
150
-
-
3543022686
-
In vivo cancer targeting and imaging with semiconductor quantum dots
-
DOI 10.1038/nbt994
-
Gao X, Cui Y, Levenson RM, et al. In vivo cancer targeting and imaging with semiconductor quantum dots. Nat Biotechnol. 2004;22:969-976. (Pubitemid 39014473)
-
(2004)
Nature Biotechnology
, vol.22
, Issue.8
, pp. 969-976
-
-
Gao, X.1
Cui, Y.2
Levenson, R.M.3
Chung, L.W.K.4
Nie, S.5
-
151
-
-
43949092126
-
Imaging of primary and metastatic pancreatic cancer using a fluorophore-conjugated anti-CA19-9 antibody for surgical navigation
-
McElroy M, Kaushal S, Luiken GA, et al. Imaging of primary and metastatic pancreatic cancer using a fluorophore-conjugated anti-CA19-9 antibody for surgical navigation. World J Surg. 2008;32:1057-1066.
-
(2008)
World J Surg
, vol.32
, pp. 1057-1066
-
-
McElroy, M.1
Kaushal, S.2
Luiken, G.A.3
-
152
-
-
54349097441
-
Fluorophoreconjugated anti-CEA antibody for the intraoperative imaging of pancreatic and colorectal cancer
-
Kaushal S, McElroy MK, Luiken GA, et al. Fluorophoreconjugated anti-CEA antibody for the intraoperative imaging of pancreatic and colorectal cancer. J Gastrointest Surg. 2008;12:1938-1950.
-
(2008)
J Gastrointest Surg
, vol.12
, pp. 1938-1950
-
-
Kaushal, S.1
McElroy, M.K.2
Luiken, G.A.3
-
153
-
-
77950419552
-
From combinatorial peptide selection to drug prototype (II): Targeting the epidermal growth factor receptor pathway
-
Cardo-Vila M, Giordano RJ, Sidman RL, et al. From combinatorial peptide selection to drug prototype (II): targeting the epidermal growth factor receptor pathway. Proc Natl Acad Sci USA. 2010;107:5118-5123.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 5118-5123
-
-
Cardo-Vila, M.1
Giordano, R.J.2
Sidman, R.L.3
-
154
-
-
39049102137
-
Nerve growth factor is a potential therapeutic target in breast cancer
-
DOI 10.1158/0008-5472.CAN-07-1183
-
Adriaenssens E, Vanhecke E, Saule P, et al. Nerve growth factor is a potential therapeutic target in breast cancer. Cancer Res. 2008;68:346-351. (Pubitemid 351380059)
-
(2008)
Cancer Research
, vol.68
, Issue.2
, pp. 346-351
-
-
Adriaenssens, E.1
Vanhecke, E.2
Saule, P.3
Mougel, A.4
Page, A.5
Romon, R.6
Nurcombe, V.7
Le Bourhis, X.8
Hondermarck, H.9
-
155
-
-
77956903170
-
Vascular endothelial growth factor as an anti-angiogenic target for cancer therapy
-
Niu G, Chen X. Vascular endothelial growth factor as an anti-angiogenic target for cancer therapy. Curr Drug Targets. 2010;11:1000-1017.
-
(2010)
Curr Drug Targets
, vol.11
, pp. 1000-1017
-
-
Niu, G.1
Chen, X.2
-
156
-
-
79957701112
-
EGFR targeted PLGA nanoparticles using gemcitabine for treatment of pancreatic cancer
-
Aggarwal S, Yadav S, Gupta S. EGFR targeted PLGA nanoparticles using gemcitabine for treatment of pancreatic cancer. J Biomed Nanotechnol. 2011;7:137-138.
-
(2011)
J Biomed Nanotechnol
, vol.7
, pp. 137-138
-
-
Aggarwal, S.1
Yadav, S.2
Gupta, S.3
-
157
-
-
75549103960
-
Physical structure and behavior of lipids and lipid enzymes
-
Bangham AD. Physical structure and behavior of lipids and lipid enzymes. Adv Lipid Res. 1963;1:65-104.
-
(1963)
Adv Lipid Res
, vol.1
, pp. 65-104
-
-
Bangham, A.D.1
-
158
-
-
0015379583
-
Lysosomal localization of-fructofuranosidase-containing liposomes injected into rats
-
Gregoriadis G, Ryman BE. Lysosomal localization of-fructofuranosidase- containing liposomes injected into rats. Biochem J. 1972;129:123-133.
-
(1972)
Biochem J
, vol.129
, pp. 123-133
-
-
Gregoriadis, G.1
Ryman, B.E.2
-
159
-
-
0030681273
-
Liposomes: Opportunities in drug delivery
-
Allen TM. Liposomes: opportunities in drug delivery. Drugs. 1997;54(Suppl 4):8-14.
-
(1997)
Drugs
, vol.54
, Issue.SUPPL. 4
, pp. 8-14
-
-
Allen, T.M.1
-
160
-
-
0032851735
-
Immunoliposomes for the targeted delivery of antitumor drugs
-
DOI 10.1016/S0169-409X(99)00043-5, PII S0169409X99000435
-
Mastrobattista E, Koning GA, Storm G. Immunoliposomes for the targeted delivery of antitumor drugs. Adv Drug Deliv Rev. 1999;40:103-127. (Pubitemid 29486607)
-
(1999)
Advanced Drug Delivery Reviews
, vol.40
, Issue.1-2
, pp. 103-127
-
-
Mastrobattista, E.1
Koning, G.A.2
Storm, G.3
-
162
-
-
0036605068
-
Integrin expression in colon cancer cells is regulated by the cytoplasmic domain of the β6 integrin subunit
-
DOI 10.1002/ijc.10397
-
Niu J, Dorahy DJ, Gu X, et al. Integrin expression in colon cancer cells is regulated by the cytoplasmic domain of the beta6 integrin subunit. Int J Cancer. 2002;99:529-537. (Pubitemid 34461605)
-
(2002)
International Journal of Cancer
, vol.99
, Issue.4
, pp. 529-537
-
-
Niu, J.1
Dorahy, D.J.2
Gu, X.3
Scott, R.J.4
Draganic, B.5
Ahmed, N.6
Agrez, M.V.7
-
163
-
-
0032824375
-
Possibility of active targeting to tumor tissues with liposomes
-
DOI 10.1016/S0169-409X(99)00042-3, PII S0169409X99000423
-
Maruyama K, Ishida O, Takizawa T, et al. Possibility of active targeting to tumor tissues with liposomes. Adv Drug Deliv Rev. 1999;40:89-102. (Pubitemid 29486606)
-
(1999)
Advanced Drug Delivery Reviews
, vol.40
, Issue.1-2
, pp. 89-102
-
-
Maruyama, K.1
Ishida, O.2
Takizawa, T.3
Moribe, K.4
-
164
-
-
0023280158
-
Fate and behavior of liposomes in vivo: A review of controlling factors
-
Senior JH. Fate and behavior of liposomes in vivo: a review of controlling factors. Crit Rev Ther Drug Carrier Syst. 1987;3:123-193. (Pubitemid 17219201)
-
(1987)
Critical Reviews in Therapeutic Drug Carrier Systems
, vol.3
, Issue.2
, pp. 123-193
-
-
Senior, J.H.1
-
165
-
-
0026541171
-
Serum opsonins and liposomes: Their interaction and opsonophagocytosis
-
Patel HM. Serum opsonins and liposomes: their interaction and opsonophagocytosis. Crit Rev Ther Drug Carrier Syst. 1992;9:39-90.
-
(1992)
Crit Rev Ther Drug Carrier Syst
, vol.9
, pp. 39-90
-
-
Patel, H.M.1
-
166
-
-
0025185802
-
Evaluation in vitro of adriamycin immunoconjugates synthesized using an acid-sensitive hydrazone linker
-
Greenfield RS, Kaneko T, Daues A, et al. Evaluation in vitro of adriamycin immunoconjugates synthesized using an acidsensitive hydrazone linker. Cancer Res. 1990;50:6600-6607. (Pubitemid 20348786)
-
(1990)
Cancer Research
, vol.50
, Issue.20
, pp. 6600-6607
-
-
Greenfield, R.S.1
Kaneko, T.2
Daues, A.3
Edson, M.A.4
Fitzgerald, K.A.5
Olech, L.J.6
Grattan, J.A.7
Spitalny, G.L.8
Braslawsky, G.R.9
-
167
-
-
0027218284
-
Cure of xenografted human carcinomas by BR96-doxorubicin immunoconjugates
-
Trail PA, Willner D, Lasch SJ, et al. Cure of xenografted human carcinomas by BR96-doxorubicin immunoconjugates. Science. 1993;261:212-215. (Pubitemid 23265398)
-
(1993)
Science
, vol.261
, Issue.5118
, pp. 212-215
-
-
Trail, P.A.1
Willner, D.2
Lasch, S.J.3
Henderson, A.J.4
Hofstead, S.5
Casazza, A.M.6
Firestone, R.A.7
Hellstrom, I.8
Hellstrom, K.E.9
-
168
-
-
0037871905
-
BR96 conjugates of highly potent anthracyclines
-
DOI 10.1016/S0960-894X(03)00375-5
-
King HD, Staab AJ, Pham-Kaplita K, et al. BR96 conjugates of highly potent anthracyclines. Bioorg Med Chem Lett. 2003;13:2119-2122. (Pubitemid 36694287)
-
(2003)
Bioorganic and Medicinal Chemistry Letters
, vol.13
, Issue.13
, pp. 2119-2122
-
-
King, H.D.1
Staab, A.J.2
Pham-Kaplita, K.3
Yurgaitis, D.4
Firestone, R.A.5
Lasch, S.J.6
Trail, P.A.7
-
170
-
-
0032946945
-
Targetability of novel immunoliposomes prepared by a new antibody conjugation technique
-
DOI 10.1016/S0378-5173(99)00002-2, PII S0378517399000022
-
Bendas G, Krause A, Bakowsky U, et al. Targetability of novel immunoliposomes prepared by a new antibody conjugation technique. Int J Pharm. 1999;181:79-93. (Pubitemid 29199890)
-
(1999)
International Journal of Pharmaceutics
, vol.181
, Issue.1
, pp. 79-93
-
-
Bendas, G.1
Krause, A.2
Bakowsky, U.3
Vogel, J.4
Rothe, U.5
-
171
-
-
0030876540
-
Immunoliposomes bearing polyethyleneglycol-coupled Fab' fragment show prolonged circulation time and high extravasation into targeted solid tumors in vivo
-
DOI 10.1016/S0014-5793(97)00905-8, PII S0014579397009058
-
Maruyama K, Takahashi N, Tagawa T, et al. Immunoliposomes bearing polyethyleneglycol-coupled Fab' fragment show prolonged circulation time and high extravasation into targeted solid tumors in vivo. FEBS Lett. 1997;413:177-180. (Pubitemid 27348659)
-
(1997)
FEBS Letters
, vol.413
, Issue.1
, pp. 177-180
-
-
Maruyama, K.1
Takahashi, N.2
Tagawa, T.3
Nagaike, K.4
Iwatsuru, M.5
-
172
-
-
0016666851
-
The resistance of glycoproteins to proteolytic inactivation
-
Vegarud G, Christensen TB. The resistance of glycoproteins to proteolytic inactivation. Acta Chem Scand B. 1975;29:887-888.
-
(1975)
Acta Chem Scand B
, vol.29
, pp. 887-888
-
-
Vegarud, G.1
Christensen, T.B.2
-
173
-
-
75149183678
-
Glycosylation of therapeutic proteins: An effective strategy to optimize efficacy
-
Sola RJ, Griebenow K. Glycosylation of therapeutic proteins: an effective strategy to optimize efficacy. BioDrugs. 2010; 24:9-21.
-
(2010)
BioDrugs
, vol.24
, pp. 9-21
-
-
Sola, R.J.1
Griebenow, K.2
-
174
-
-
35248882544
-
Modulation of protein biophysical properties by chemical glycosylation: Biochemical insights and biomedical implications
-
DOI 10.1007/s00018-007-6551-y
-
Sola RJ, Rodriguez-Martinez JA, Griebenow K. Modulation of protein biophysical properties by chemical glycosylation: biochemical insights and biomedical implications. Cell Mol Life Sci. 2007;64:2133-2152. (Pubitemid 350092414)
-
(2007)
Cellular and Molecular Life Sciences
, vol.64
, Issue.16
, pp. 2133-2152
-
-
Sola, R.J.1
Rodriguez-Martinez, J.A.2
Griebenow, K.3
-
175
-
-
77956545725
-
Long-lasting antitumor protection by anti-CD20 antibody through cellular immune response
-
Abes R, Gelize E, Fridman WH, et al. Long-lasting antitumor protection by anti-CD20 antibody through cellular immune response. Blood. 2010;116:926-934.
-
(2010)
Blood
, vol.116
, pp. 926-934
-
-
Abes, R.1
Gelize, E.2
Fridman, W.H.3
-
177
-
-
0032716364
-
Selection of antibodies for intracellular function using a two-hybrid in vivo system
-
DOI 10.1073/pnas.96.21.11723
-
Visintin M, Tse E, Axelson H, et al. Selection of antibodies for intracellular function using a two-hybrid in vivo system. Proc Natl Acad Sci USA. 1999;96:11723-11728. (Pubitemid 29502799)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.21
, pp. 11723-11728
-
-
Visintin, M.1
Tse, E.2
Axelson, H.3
Rabbitts, T.H.4
Cattaneo, A.5
-
179
-
-
34548522063
-
Alternative non-antibody scaffolds for molecular recognition
-
DOI 10.1016/j.copbio.2007.04.010, PII S0958166907000808, Protein technologies / Systems Biology
-
Skerra A. Alternative non-antibody scaffolds for molecular recognition. Curr Opin Biotechnol. 2007;18:295-304. (Pubitemid 47385180)
-
(2007)
Current Opinion in Biotechnology
, vol.18
, Issue.4
, pp. 295-304
-
-
Skerra, A.1
|