메뉴 건너뛰기




Volumn 73, Issue 6, 1997, Pages 865-870

Targeting the tumor vasculature: Inhibition of tumor growth by a vascular endothelial growth factor-toxin conjugate

Author keywords

[No Author keywords available]

Indexed keywords

DIPHTHERIA TOXIN; ENDOTHELIAL CELL GROWTH FACTOR; IMMUNOTOXIN; LYMPHOKINE; VASCULOTROPIN; VASCULOTROPIN A;

EID: 0031564123     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19971210)73:6<865::AID-IJC17>3.0.CO;2-3     Document Type: Article
Times cited : (85)

References (43)
  • 1
    • 0028028308 scopus 로고
    • Angiogenesis inhibition: A review
    • AUERBACH, W. and AUERBACH, R., Angiogenesis inhibition: a review. Pharmacol. Ther., 63, 265-311 (1994).
    • (1994) Pharmacol. Ther. , vol.63 , pp. 265-311
    • Auerbach, W.1    Auerbach, R.2
  • 3
    • 0027482251 scopus 로고
    • Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in adenocarcinomas of the gastrointestinal tract
    • BROWN, L.F., BERSE, B., JACKMAN, R.W., TONGNAZZI, K., MANSEAU, E.J., SENGER, D.R. and DVORAK, H.F., Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in adenocarcinomas of the gastrointestinal tract. Cancer Res., 53, 4727-4735 (1993).
    • (1993) Cancer Res. , vol.53 , pp. 4727-4735
    • Brown, L.F.1    Berse, B.2    Jackman, R.W.3    Tongnazzi, K.4    Manseau, E.J.5    Senger, D.R.6    Dvorak, H.F.7
  • 5
    • 0027368441 scopus 로고
    • Eradication of large solid tumors in mice with an immunotoxin directed against the tumor vasculature
    • BURROWS, F.J. and THORPE, P.E., Eradication of large solid tumors in mice with an immunotoxin directed against the tumor vasculature. Proc. nat. Acad. Sci. (Wash.), 90, 8996-9000 (1993).
    • (1993) Proc. Nat. Acad. Sci. (Wash.) , vol.90 , pp. 8996-9000
    • Burrows, F.J.1    Thorpe, P.E.2
  • 6
    • 0028030125 scopus 로고
    • Vascular targeting - A new approach to the therapy of solid tumors
    • BURROWS, F.J. and THORPE, P.E., Vascular targeting - a new approach to the therapy of solid tumors. Pharmacol. Ther., 64, 155-174 (1994).
    • (1994) Pharmacol. Ther. , vol.64 , pp. 155-174
    • Burrows, F.J.1    Thorpe, P.E.2
  • 7
    • 13344259980 scopus 로고    scopus 로고
    • Heterodimers of placenta growth factor/vascular endothelial growth factor. Endothelial activity, tumor cell expression, and high affinity binding to Flk-1/KDR
    • CAO, Y. CHEN, H., ZHOU, L., CHIANG, M.K., ANAND-APTE, B., WETHERBEE, J.A., WANG, Y., FANG, F., FLANAGAN, J.G. and TSANG, M.L., Heterodimers of placenta growth factor/vascular endothelial growth factor. Endothelial activity, tumor cell expression, and high affinity binding to Flk-1/KDR. J. biol. Chem., 271, 3154-3162 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 3154-3162
    • Cao, Y.1    Chen, H.2    Zhou, L.3    Chiang, M.K.4    Anand-Apte, B.5    Wetherbee, J.A.6    Wang, Y.7    Fang, F.8    Flanagan, J.G.9    Tsang, M.L.10
  • 8
    • 0026572345 scopus 로고
    • The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor
    • DE VRIES, C., ESCOBEDO, J.A., UENO, H., HOUCK, K.A., FERRARA, N. and WILLIAMS, L.T., The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science, 255, 989-991 (1992).
    • (1992) Science , vol.255 , pp. 989-991
    • De Vries, C.1    Escobedo, J.A.2    Ueno, H.3    Houck, K.A.4    Ferrara, N.5    Williams, L.T.6
  • 9
    • 0020081554 scopus 로고
    • Endothelial cell proliferation as a novel approach to targeting tumour therapy
    • DENEKAMP, J., Endothelial cell proliferation as a novel approach to targeting tumour therapy. Brit. J. Cancer, 45, 136-139 (1982).
    • (1982) Brit. J. Cancer , vol.45 , pp. 136-139
    • Denekamp, J.1
  • 10
  • 11
    • 0029047695 scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor: An important mediator of angiogenesis in malignancy and inflammation
    • DVORAK, H.F., DETMAR, M., CLAFFEY, K.P., NAGY, J.A., VAN DE WATER, L. and SENGER, D.R., Vascular permeability factor/vascular endothelial growth factor: an important mediator of angiogenesis in malignancy and inflammation. Int. Arch. Allerg. Immunol., 107, 233-235 (1995).
    • (1995) Int. Arch. Allerg. Immunol. , vol.107 , pp. 233-235
    • Dvorak, H.F.1    Detmar, M.2    Claffey, K.P.3    Nagy, J.A.4    Van De Water, L.5    Senger, D.R.6
  • 12
    • 0029127218 scopus 로고
    • The role of vascular endothelial growth factor in pathological angiogenesis
    • FERRARA, N., The role of vascular endothelial growth factor in pathological angiogenesis. Breast Cancer Res. Treat., 36, 127-137 (1995).
    • (1995) Breast Cancer Res. Treat. , vol.36 , pp. 127-137
    • Ferrara, N.1
  • 13
    • 0031039243 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factor
    • FERRARA, N. and DAVIS-SMYTH, T., The biology of vascular endothelial growth factor. Endocrinol. Rev., 18, 4-25 (1997).
    • (1997) Endocrinol. Rev. , vol.18 , pp. 4-25
    • Ferrara, N.1    Davis-Smyth, T.2
  • 14
    • 0025141337 scopus 로고
    • What is the evidence that tumors are angiogenesis dependent?
    • FOLKMAN, J., What is the evidence that tumors are angiogenesis dependent? J. nat. Cancer Inst., 82, 4-6 (1990).
    • (1990) J. Nat. Cancer Inst. , vol.82 , pp. 4-6
    • Folkman, J.1
  • 16
    • 0027691857 scopus 로고
    • Basic fibroblast growth factor. Pseudomonas exotoxin chimeric proteins: Comparison with acidic fibroblast growth factor-Pseudomonas exotoxin
    • GAWLAK, S.L., PASTAN, I. and SIEGALL, C.B., Basic fibroblast growth factor. Pseudomonas exotoxin chimeric proteins: comparison with acidic fibroblast growth factor-Pseudomonas exotoxin. Bioconj. Chem., 4, 483-489 (1993).
    • (1993) Bioconj. Chem. , vol.4 , pp. 483-489
    • Gawlak, S.L.1    Pastan, I.2    Siegall, C.B.3
  • 17
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • HANAHAN, D. and FOLKMAN, J., Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell, 86, 353-364 (1996).
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 18
    • 0031026481 scopus 로고    scopus 로고
    • Tumor infarction in mice by antibody-directed targeting of tissue factor to tumor vasculature
    • HUANG, X., MOLEMA, G., KING, S., WATKINS, L., EDGINOTON, T.S. and THORPE, P.E., Tumor infarction in mice by antibody-directed targeting of tissue factor to tumor vasculature. Science, 275, 547-550 (1997).
    • (1997) Science , vol.275 , pp. 547-550
    • Huang, X.1    Molema, G.2    King, S.3    Watkins, L.4    Edginoton, T.S.5    Thorpe, P.E.6
  • 19
    • 0026314720 scopus 로고
    • Therapeutic implications of tumor physiology
    • JAIN, R.K., Therapeutic implications of tumor physiology. Curr. Opin. Oncol., 3, 1105-1108 (1991).
    • (1991) Curr. Opin. Oncol. , vol.3 , pp. 1105-1108
    • Jain, R.K.1
  • 21
    • 0030026897 scopus 로고    scopus 로고
    • A novel vascular endothelial growth factor, VEGF-C, is ligand for the FLT4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases
    • JOUKOV, V., PAJUSOLA, K., KAIPAINEN, A., CHILOV, D., LATHINEN, I., KUKK, E., SAKESELA, O., KALKKINEN, N. and ALITALO, K., A novel vascular endothelial growth factor, VEGF-C, is ligand for the FLT4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases. EMBO J., 15, 290-298 (1996).
    • (1996) EMBO J. , vol.15 , pp. 290-298
    • Joukov, V.1    Pajusola, K.2    Kaipainen, A.3    Chilov, D.4    Lathinen, I.5    Kukk, E.6    Sakesela, O.7    Kalkkinen, N.8    Alitalo, K.9
  • 23
    • 0027197245 scopus 로고
    • Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
    • KIM, K.J., LI, B., WINER, J., ARMANINI, M., GILLET, N., PHILLIPS, H. and FERRARA, N., Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature (Lond.), 362, 841-844 (1993).
    • (1993) Nature (Lond.) , vol.362 , pp. 841-844
    • Kim, K.J.1    Li, B.2    Winer, J.3    Armanini, M.4    Gillet, N.5    Phillips, H.6    Ferrara, N.7
  • 24
    • 0029166443 scopus 로고
    • Regulation of the expression of the VEGF/VPF and its receptors: Role in tumor angiogenesis
    • KOLCH, W., MARTINY-BARON, G., KIESER, A. and MARME, D., Regulation of the expression of the VEGF/VPF and its receptors: role in tumor angiogenesis. Breast Cancer Res. Treat., 36, 139-155 (1995).
    • (1995) Breast Cancer Res. Treat. , vol.36 , pp. 139-155
    • Kolch, W.1    Martiny-Baron, G.2    Kieser, A.3    Marme, D.4
  • 25
    • 0029383677 scopus 로고
    • Tumor targeting through fibroblast growth factor receptors
    • LAPPI, D.A., Tumor targeting through fibroblast growth factor receptors. Semin. Cancer Biol., 6, 279-288 (1995).
    • (1995) Semin. Cancer Biol. , vol.6 , pp. 279-288
    • Lappi, D.A.1
  • 26
    • 0025803630 scopus 로고
    • The basic fibroblast growth factor-saporin mitotoxin acts through the basic fibroblast growth factor receptor
    • LAPPI, D.A., MAHER, P.A., MARTINEAU, D. and BAIRD, A., The basic fibroblast growth factor-saporin mitotoxin acts through the basic fibroblast growth factor receptor. J. Cell Physiol., 147, 17-26 (1991).
    • (1991) J. Cell Physiol. , vol.147 , pp. 17-26
    • Lappi, D.A.1    Maher, P.A.2    Martineau, D.3    Baird, A.4
  • 27
    • 0029962242 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-related protein: A ligand and specific activator of the tyrosine kinase receptor Flt4
    • LEE, J., GRAY, A., YUAN, J., LUOH, S-M., AVRAHAM, M. and WOOD, W.I., Vascular endothelial growth factor-related protein: a ligand and specific activator of the tyrosine kinase receptor Flt4. Proc. nat. Acad. Sci. (Wash.), 93, 1988-1992 (1996).
    • (1996) Proc. Nat. Acad. Sci. (Wash.) , vol.93 , pp. 1988-1992
    • Lee, J.1    Gray, A.2    Yuan, J.3    Luoh, S.-M.4    Avraham, M.5    Wood, W.I.6
  • 28
    • 0026052391 scopus 로고
    • Isolation of a human placenta cDNA coding for protein related to the vascular permiability factor
    • MAGLIONE, D., GUERRIERO, V., VIGLIETTO, G., DELLI-BOVI, P. and PERSICO, M.G., Isolation of a human placenta cDNA coding for protein related to the vascular permiability factor. Proc. nat. Acad Sci. (Wash.), 88, 9267-9271 (1991).
    • (1991) Proc. Nat. Acad Sci. (Wash.) , vol.88 , pp. 9267-9271
    • Maglione, D.1    Guerriero, V.2    Viglietto, G.3    Delli-Bovi, P.4    Persico, M.G.5
  • 29
    • 15144358851 scopus 로고    scopus 로고
    • Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis
    • MAISONPIERRE, P.C. and 13 OTHERS, Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science, 277, 55-60 (1997).
    • (1997) Science , vol.277 , pp. 55-60
    • Maisonpierre, P.C.1
  • 30
    • 0028174337 scopus 로고
    • Glioblastoma growth inhibited in vivo by a dominant-negative flk-1 mutant
    • MILLAUER, B., SHAWVER, L.K., PLATE, K.H., RISAU, W. and ULLRICH, A., Glioblastoma growth inhibited in vivo by a dominant-negative flk-1 mutant. Nature (Lond.), 367, 576-579 (1994).
    • (1994) Nature (Lond.) , vol.367 , pp. 576-579
    • Millauer, B.1    Shawver, L.K.2    Plate, K.H.3    Risau, W.4    Ullrich, A.5
  • 31
    • 0027466849 scopus 로고
    • High affinity binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis
    • MILLAUER, B., WIZIGMANN-VOSS, S., SCHNURCH, H., MARTINEZ, R., MOLLER, N.P., RISAU, W. and ULRICH, A., High affinity binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell, 72, 835-846 (1993).
    • (1993) Cell , vol.72 , pp. 835-846
    • Millauer, B.1    Wizigmann-Voss, S.2    Schnurch, H.3    Martinez, R.4    Moller, N.P.5    Risau, W.6    Ulrich, A.7
  • 32
    • 0029021904 scopus 로고
    • Endothelial receptor tyrosine kinases involved in angiogenesis
    • MUSTONEN, T. and ALITALO, K., Endothelial receptor tyrosine kinases involved in angiogenesis. J. Cell Biol., 129, 895-898 (1995).
    • (1995) J. Cell Biol. , vol.129 , pp. 895-898
    • Mustonen, T.1    Alitalo, K.2
  • 34
    • 0028153737 scopus 로고
    • Vascular permeability factor expression in normal and neoplastic human ovaries
    • OLSON, T.A., MOHANRAJ, D., CARSON, L.F. and RAMAKRISHNAN, S., Vascular permeability factor expression in normal and neoplastic human ovaries. Cancer Res., 54, 276-280 (1994).
    • (1994) Cancer Res. , vol.54 , pp. 276-280
    • Olson, T.A.1    Mohanraj, D.2    Carson, L.F.3    Ramakrishnan, S.4
  • 35
    • 0029934658 scopus 로고    scopus 로고
    • In vivo neutralization of vascular endothelial growth factor (VEGF)/vascular permeability factor (VPF) inhibits ovarian carcinoma-associated ascites formation and tumor growth
    • OLSON, T.A., MOHANRAJ, D. and RAMAKRISHNAN, S., In vivo neutralization of vascular endothelial growth factor (VEGF)/vascular permeability factor (VPF) inhibits ovarian carcinoma-associated ascites formation and tumor growth. Int. J. Oncol. 8, 505-511 (1996).
    • (1996) Int. J. Oncol. , vol.8 , pp. 505-511
    • Olson, T.A.1    Mohanraj, D.2    Ramakrishnan, S.3
  • 36
    • 0027432324 scopus 로고
    • Up-regulalion of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis
    • PLATE, K.H., BREIER, G., MILLAUER, B., ULLRICH, A. and RISAU, W., Up-regulalion of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis. Cancer Res., 53, 5822-5827 (1993).
    • (1993) Cancer Res. , vol.53 , pp. 5822-5827
    • Plate, K.H.1    Breier, G.2    Millauer, B.3    Ullrich, A.4    Risau, W.5
  • 37
    • 0027249239 scopus 로고
    • Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium
    • QUINN, T., PETERS, K.G., DE VRIES, C., FERRARA, N. and WILLIAMS, L.T., Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium. Proc. nat. Acad. Sci. (Wash.), 90, 7533-7537 (1993).
    • (1993) Proc. Nat. Acad. Sci. (Wash.) , vol.90 , pp. 7533-7537
    • Quinn, T.1    Peters, K.G.2    De Vries, C.3    Ferrara, N.4    Williams, L.T.5
  • 38
    • 0029915612 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-toxin conjugate specifically inhibits KDR/flk-1-positive endothelial cell proliferation in vitro and angiogenesis in vivo
    • RAMAKRISHNAN, S., OLSON, T.A., BAUCH, V.L. and MOHANRAJ, D., Vascular endothelial growth factor-toxin conjugate specifically inhibits KDR/flk-1-positive endothelial cell proliferation in vitro and angiogenesis in vivo. Cancer Res., 56, 1324-1330 (1996).
    • (1996) Cancer Res. , vol.56 , pp. 1324-1330
    • Ramakrishnan, S.1    Olson, T.A.2    Bauch, V.L.3    Mohanraj, D.4
  • 39
    • 0025259592 scopus 로고
    • Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase (flt) closely related to the fms family
    • SHIBUYA, M., YAMAGUCHI, S., YAMANE, A., IKADA, T., TOJO, T., MATSUSHIME, H. and SATO, M., Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase (flt) closely related to the fms family. Oncogens, 8, 519-527 (1990).
    • (1990) Oncogens , vol.8 , pp. 519-527
    • Shibuya, M.1    Yamaguchi, S.2    Yamane, A.3    Ikada, T.4    Tojo, T.5    Matsushime, H.6    Sato, M.7
  • 40
    • 0028048221 scopus 로고
    • Targeted toxins as anticancer agents
    • SIEGALL, C.B., Targeted toxins as anticancer agents. Cancer, 74, 1006-1012 (1994).
    • (1994) Cancer , vol.74 , pp. 1006-1012
    • Siegall, C.B.1
  • 41
    • 0028112691 scopus 로고
    • In vivo activities of acidic fibroblast growth factor-Pseudomonas exotoxin fusion proteins
    • SIEGALL, C.B., GAWLAK, S.L., CHACE, D.F., MERWIN, J.R. and PASTAN, I., In vivo activities of acidic fibroblast growth factor-Pseudomonas exotoxin fusion proteins. Bioconj. Chem., 5, 77-83 (1994).
    • (1994) Bioconj. Chem. , vol.5 , pp. 77-83
    • Siegall, C.B.1    Gawlak, S.L.2    Chace, D.F.3    Merwin, J.R.4    Pastan, I.5
  • 43
    • 0025739016 scopus 로고
    • Identification of a new endothelial cell growth factor receptor tyrosine kinase
    • TERMAN, B.I., CARRION, M.E., KOVACS, E., RASMUSSEN, B.A., EDDY, R.L. and SHOWS, T.B. Identification of a new endothelial cell growth factor receptor tyrosine kinase. Oncogene, 6, 519-524 (1991).
    • (1991) Oncogene , vol.6 , pp. 519-524
    • Terman, B.I.1    Carrion, M.E.2    Kovacs, E.3    Rasmussen, B.A.4    Eddy, R.L.5    Shows, T.B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.