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Volumn 14, Issue 1, 2000, Pages 129-135

Treatment of refractory Hodgkin's lymphoma patients with an anti-CD25 ricin A-chain immunotoxin

Author keywords

CD25 antigen; Clinical trial; Hodgkin's lymphoma; Immunotoxins

Indexed keywords

IMMUNOTOXIN; INTERLEUKIN 2 RECEPTOR; MONOCLONAL ANTIBODY; RICIN A;

EID: 0033978156     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2401626     Document Type: Article
Times cited : (78)

References (55)
  • 2
    • 0022553175 scopus 로고
    • Twenty years of MOPP therapy for Hodgkin's lymphoma
    • Longo IL, Young RC, Wesley M. Twenty years of MOPP therapy for Hodgkin's lymphoma. J Clin Oncol 1986; 4: 1295-1306.
    • (1986) J Clin Oncol , vol.4 , pp. 1295-1306
    • Longo, I.L.1    Young, R.C.2    Wesley, M.3
  • 4
    • 0025923704 scopus 로고
    • Anti-My9-blocked ricin: An immunotoxin for selective targeting of acute myeloid leukemia cells
    • Ro DC, Griffin JD, Belvin M, Blaettler WA, Lambert JM, Ritz J. Anti-My9-blocked ricin: an immunotoxin for selective targeting of acute myeloid leukemia cells. Bload 1991; 77: 2404-2412.
    • (1991) Bload , vol.77 , pp. 2404-2412
    • Ro, D.C.1    Griffin, J.D.2    Belvin, M.3    Blaettler, W.A.4    Lambert, J.M.5    Ritz, J.6
  • 6
    • 0029983251 scopus 로고    scopus 로고
    • Molecular single cell analysis demonstrates the derivation of a peripheral blood derived cell line (L1236) from the Hodgkin/Reed-Sternberg cells of a Hodgkin's lymphoma patient
    • Kanzler H, Hansmann M-L, Kapp U, Wolf J, Diehl V, Rajewsky K, Kueppers R. Molecular single cell analysis demonstrates the derivation of a peripheral blood derived cell line (L1236) from the Hodgkin/Reed-Sternberg cells of a Hodgkin's lymphoma patient. Blood 1996; 87: 3429-3436.
    • (1996) Blood , vol.87 , pp. 3429-3436
    • Kanzler, H.1    Hansmann, M.-L.2    Kapp, U.3    Wolf, J.4    Diehl, V.5    Rajewsky, K.6    Kueppers, R.7
  • 8
    • 0030161641 scopus 로고    scopus 로고
    • Treatment of minimal residual disease in acute myelogenous leukemia (AML): Focus on immunotherapeutic options
    • Simonsson B. Treatment of minimal residual disease in acute myelogenous leukemia (AML): focus on immunotherapeutic options. Leukemia 1996; 10 (Suppl. 2): 44-52.
    • (1996) Leukemia , vol.10 , Issue.SUPPL. 2 , pp. 44-52
    • Simonsson, B.1
  • 10
    • 0030227736 scopus 로고    scopus 로고
    • Hodgkin's disease. Future treatment strategies: Fact or fiction
    • Diehl V (ed). Baillière Tindall: London
    • Schnell R, Barth S, Diehl V, Engert A. Hodgkin's disease. Future treatment strategies: fact or fiction. In Diehl V (ed). Baillières Clinical Haematology. Baillière Tindall: London, 1996, pp 573-593.
    • (1996) Baillières Clinical Haematology , pp. 573-593
    • Schnell, R.1    Barth, S.2    Diehl, V.3    Engert, A.4
  • 11
    • 0021270185 scopus 로고
    • Leu M1 and peanut agglutinin stain the neoplastic cells of Hodgkin's lymphoma
    • Hsu SM, Jaffe ES. Leu M1 and peanut agglutinin stain the neoplastic cells of Hodgkin's lymphoma. Am J Clin Pathol 1984; 82: 29-32.
    • (1984) Am J Clin Pathol , vol.82 , pp. 29-32
    • Hsu, S.M.1    Jaffe, E.S.2
  • 12
    • 0023635656 scopus 로고
    • Effect of monoclonal antibodies anti-2H9, anti-IRac, and anti-HeFi-1 on the surface antigens of Reed-Sternberg cells
    • Hsu SM, Ho YS, Hsu PL. Effect of monoclonal antibodies anti-2H9, anti-IRac, and anti-HeFi-1 on the surface antigens of Reed-Sternberg cells. J Natl Cancer Inst 1987; 79: 1091-1097.
    • (1987) J Natl Cancer Inst , vol.79 , pp. 1091-1097
    • Hsu, S.M.1    Ho, Y.S.2    Hsu, P.L.3
  • 13
    • 0021972684 scopus 로고
    • The expression of the Hodgkin's-disease-associated antigen Ki-1 in reactive and neoplastic lymphoid tissue: Evidence that Sternberg-Reed cells and histocytic malignancies are derived from activated lymphoid cells
    • Stein H, Mason DY, Gerdes J, O'Conner N, Wainscoat J, Pallesen G, Gatter K, Falini B, Delsol G, Lemke H, Schwarting R, Lennert K. The expression of the Hodgkin's-disease-associated antigen Ki-1 in reactive and neoplastic lymphoid tissue: evidence that Sternberg-Reed cells and histocytic malignancies are derived from activated lymphoid cells. Blood 1985; 66: 848-858.
    • (1985) Blood , vol.66 , pp. 848-858
    • Stein, H.1    Mason, D.Y.2    Gerdes, J.3    O'Conner, N.4    Wainscoat, J.5    Pallesen, G.6    Gatter, K.7    Falini, B.8    Delsol, G.9    Lemke, H.10    Schwarting, R.11    Lennert, K.12
  • 14
    • 0024333720 scopus 로고
    • The immunophenotype of Reed-Sternberg cells. A study of 50 cases of Hodgkin's lymphoma using fixed frozen tissue
    • Agnarsson BA, Kadin ME. The immunophenotype of Reed-Sternberg cells. A study of 50 cases of Hodgkin's lymphoma using fixed frozen tissue. Cancer 1989; 63: 2083-2087.
    • (1989) Cancer , vol.63 , pp. 2083-2087
    • Agnarsson, B.A.1    Kadin, M.E.2
  • 15
    • 0024400867 scopus 로고
    • Nodular sclerosing, mixed cellularity and lymphocyte-depleted variants of Hodgkin's lymphoma are probable dendritic cell malignancies
    • Kennedy IC, Hart DN, Colls BM. Nodular sclerosing, mixed cellularity and lymphocyte-depleted variants of Hodgkin's lymphoma are probable dendritic cell malignancies. Clin Exp Immunol 1989; 76: 324-331.
    • (1989) Clin Exp Immunol , vol.76 , pp. 324-331
    • Kennedy, I.C.1    Hart, D.N.2    Colls, B.M.3
  • 16
    • 0027453460 scopus 로고
    • The B7/BB1 antigen is expressed by Reed-Sternberg cells of Hodgkin's lymphoma and contributes to the stimulating capacity of Hodgkin's lymphoma-derived cell lines
    • Delabie J, Ceuppens JL, Vandenberghe P, de Boer M, Coorevits L, de Wolf-Peeters C. The B7/BB1 antigen is expressed by Reed-Sternberg cells of Hodgkin's lymphoma and contributes to the stimulating capacity of Hodgkin's lymphoma-derived cell lines. Blood 1993; 82: 2845-2852.
    • (1993) Blood , vol.82 , pp. 2845-2852
    • Delabie, J.1    Ceuppens, J.L.2    Vandenberghe, P.3    De Boer, M.4    Coorevits, L.5    De Wolf-Peeters, C.6
  • 17
    • 0029825903 scopus 로고    scopus 로고
    • Development of immunotoxins for potential clinical use in Hodgkin's disease
    • Barth S, Schnell R, Diehl V, Engert A. Development of immunotoxins for potential clinical use in Hodgkin's disease. Ann Oncol 1996; 7 (Suppl. 4): 135-141.
    • (1996) Ann Oncol , vol.7 , Issue.SUPPL. 4 , pp. 135-141
    • Barth, S.1    Schnell, R.2    Diehl, V.3    Engert, A.4
  • 18
    • 0027394657 scopus 로고
    • The IL-2/IL-2 receptor system: A current overview
    • Taniguchi T, Minami Y. The IL-2/IL-2 receptor system: a current overview. Cell 1993; 73: 5-8.
    • (1993) Cell , vol.73 , pp. 5-8
    • Taniguchi, T.1    Minami, Y.2
  • 19
    • 0028205130 scopus 로고
    • Recombinant single-chain immunotoxins against T and B cell leukemias
    • Kreitman RJ, Pastan I. Recombinant single-chain immunotoxins against T and B cell leukemias. Leuk Lymphoma 1994; 13: 1-10.
    • (1994) Leuk Lymphoma , vol.13 , pp. 1-10
    • Kreitman, R.J.1    Pastan, I.2
  • 20
    • 0023128587 scopus 로고
    • IL-2 receptor expression in human lymphoid lesions. Immunohistochemical study of 166 cases
    • Strauchen JA, Breakstone BA. IL-2 receptor expression in human lymphoid lesions. Immunohistochemical study of 166 cases. Am J Pathol 1987; 126: 506-512.
    • (1987) Am J Pathol , vol.126 , pp. 506-512
    • Strauchen, J.A.1    Breakstone, B.A.2
  • 21
    • 0025948173 scopus 로고
    • Immunotoxins constructed with CD25 monoclonal antibodies and deglycosylated ricin A-chain have potent antitumor effects against human Hodgkin cells in vitro and solid Hodgkin tumors in mice
    • Engert A, Martin G, Amlot P, Wijdenes J, Diehl V, Thorpe P. Immunotoxins constructed with CD25 monoclonal antibodies and deglycosylated ricin A-chain have potent antitumor effects against human Hodgkin cells in vitro and solid Hodgkin tumors in mice. Int J Cancer 1991; 49: 450-456.
    • (1991) Int J Cancer , vol.49 , pp. 450-456
    • Engert, A.1    Martin, G.2    Amlot, P.3    Wijdenes, J.4    Diehl, V.5    Thorpe, P.6
  • 25
    • 0024536437 scopus 로고
    • Optimal two-stage designs for phase II clinical trials
    • Simon R. Optimal two-stage designs for phase II clinical trials. Control Clin Trials 1989; 10: 1-10.
    • (1989) Control Clin Trials , vol.10 , pp. 1-10
    • Simon, R.1
  • 28
    • 0022897897 scopus 로고
    • A basic interactive complex program for statistical and pharmacokinetic analysis of data
    • Schumaker RC. A basic interactive complex program for statistical and pharmacokinetic analysis of data. Drug Metab Rev 1986; 17: 331-342.
    • (1986) Drug Metab Rev , vol.17 , pp. 331-342
    • Schumaker, R.C.1
  • 32
    • 0027156735 scopus 로고
    • Immunotoxins: Magic bullets or misguided missiles?
    • Vitetta ES, Thorpe PE, Uhr JW. Immunotoxins: magic bullets or misguided missiles? Immunol Today 1993; 14: 252-259.
    • (1993) Immunol Today , vol.14 , pp. 252-259
    • Vitetta, E.S.1    Thorpe, P.E.2    Uhr, J.W.3
  • 33
    • 0028127304 scopus 로고
    • Phase I clinical trial using escalating single-dose infusion of chimeric anti-CD20 monoclonal antibody (IDEC-C2B8) in patients with recurrent B-cell lymphoma
    • Maloney DG, Liles TM, Czerwinski DK, Waldichuk C, Rosenberg J, Grillo-Lopez A, Levy R. Phase I clinical trial using escalating single-dose infusion of chimeric anti-CD20 monoclonal antibody (IDEC-C2B8) in patients with recurrent B-cell lymphoma. Blood 1994; 84: 2457-2466.
    • (1994) Blood , vol.84 , pp. 2457-2466
    • Maloney, D.G.1    Liles, T.M.2    Czerwinski, D.K.3    Waldichuk, C.4    Rosenberg, J.5    Grillo-Lopez, A.6    Levy, R.7
  • 34
    • 0030954684 scopus 로고    scopus 로고
    • Recombinant RFB4 immunotoxins exhibit potent cytotoxic activity for CD22-bearing cells and tumors
    • Mansfield E, Amlot P, Pastan I, FitzGerald DJ. Recombinant RFB4 immunotoxins exhibit potent cytotoxic activity for CD22-bearing cells and tumors. Blood 1997; 90: 2020-2026.
    • (1997) Blood , vol.90 , pp. 2020-2026
    • Mansfield, E.1    Amlot, P.2    Pastan, I.3    FitzGerald, D.J.4
  • 35
    • 0032524994 scopus 로고    scopus 로고
    • Purification and characterization of lymphocyte chymase I, a granzyme implicated in perforin-mediated lysis
    • Woodard SL, Fraser SA, Winkler U, Jackson DS, Kam CM, Powers JC, Hudig D. Purification and characterization of lymphocyte chymase I, a granzyme implicated in perforin-mediated lysis. J Immunol 1998; 160: 4988-4993.
    • (1998) J Immunol , vol.160 , pp. 4988-4993
    • Woodard, S.L.1    Fraser, S.A.2    Winkler, U.3    Jackson, D.S.4    Kam, C.M.5    Powers, J.C.6    Hudig, D.7
  • 36
    • 0026806808 scopus 로고
    • Recombinant toxins containing the variable domains of the anti-tac monoclonal antibody to the interleukin-2 receptor kill malignant cells from patients with chronic lymphocylic leukemia
    • Kreitman RJ, Chaudhary VK, Kozak RW, FitzGerald DJP, Waldmann TA, Pastan I. Recombinant toxins containing the variable domains of the anti-tac monoclonal antibody to the interleukin-2 receptor kill malignant cells from patients with chronic lymphocylic leukemia. Blood 1992; 80: 2344-2352.
    • (1992) Blood , vol.80 , pp. 2344-2352
    • Kreitman, R.J.1    Chaudhary, V.K.2    Kozak, R.W.3    Fitzgerald, D.J.P.4    Waldmann, T.A.5    Pastan, I.6
  • 37
    • 0027223468 scopus 로고
    • Cytotoxic activities of recombinant immunotoxins composed of Pseudomonas toxin or Diphtheria toxin toward lymphocytes from patients with adult T cell leukemia
    • Kreitman RJ, Chaudhary VK, Waldmann TA, Hanchard B, Cranston B, FitzGerald DJP, Pastan I. Cytotoxic activities of recombinant immunotoxins composed of Pseudomonas toxin or Diphtheria toxin toward lymphocytes from patients with adult T cell leukemia. Leukemia 1993; 7: 553-562.
    • (1993) Leukemia , vol.7 , pp. 553-562
    • Kreitman, R.J.1    Chaudhary, V.K.2    Waldmann, T.A.3    Hanchard, B.4    Cranston, B.5    FitzGerald, D.J.P.6    Pastan, I.7
  • 40
    • 0023529699 scopus 로고
    • Diphtheria toxin receptor binding domain substitution with interleukin-2: Genetic construction and properties of a diphtheria toxin-related interleukin-2 fusion protein
    • Williams DP, Parker K, Bacha P, Bishai W, Borowski M, Genbauffe F, Strom TB, Murphy JR. Diphtheria toxin receptor binding domain substitution with interleukin-2: genetic construction and properties of a diphtheria toxin-related interleukin-2 fusion protein. Prot Eng 1987; 1: 493-498.
    • (1987) Prot Eng , vol.1 , pp. 493-498
    • Williams, D.P.1    Parker, K.2    Bacha, P.3    Bishai, W.4    Borowski, M.5    Genbauffe, F.6    Strom, T.B.7    Murphy, J.R.8
  • 47
    • 0025122427 scopus 로고
    • Evaluation of ricin A-chain-containing inimunotoxins directed against the CD30 antigen as potential reagents for the treatment of Hodgkin's lymphoma
    • Engert A, Burrows F, Jung W, Tazzari PL, Stein H, Pfreundschuh M, Diehl V, Thorpe P. Evaluation of ricin A-chain-containing inimunotoxins directed against the CD30 antigen as potential reagents for the treatment of Hodgkin's lymphoma. Cancer Res 1990; 50: 84-88.
    • (1990) Cancer Res , vol.50 , pp. 84-88
    • Engert, A.1    Burrows, F.2    Jung, W.3    Tazzari, P.L.4    Stein, H.5    Pfreundschuh, M.6    Diehl, V.7    Thorpe, P.8
  • 48
    • 0028908960 scopus 로고
    • Shedding of the soluble form of CD30 from the Hodgkin-analogous cell line L540 is strongly inhibited by a new CD30-specific antibody (Ki-4)
    • Horn-Lohrens O, Tiemann M, Lange H, Kobarg J, Hafner M, Hansen H, Sterry W, Parwaresch RM, Lemke H. Shedding of the soluble form of CD30 from the Hodgkin-analogous cell line L540 is strongly inhibited by a new CD30-specific antibody (Ki-4). Int J Cancer 1995; 60: 539-544.
    • (1995) Int J Cancer , vol.60 , pp. 539-544
    • Horn-Lohrens, O.1    Tiemann, M.2    Lange, H.3    Kobarg, J.4    Hafner, M.5    Hansen, H.6    Sterry, W.7    Parwaresch, R.M.8    Lemke, H.9
  • 49
    • 0028828078 scopus 로고
    • Development of new ricin A-chain immunotoxins with potent anti-tumor effects against human Hodgkin cells in vitro and disseminated Hodgkin tumors in SCID mice using high-affinity monoclonal antibodies directed against the CD30 antigen
    • Schnell R, Linnartz C, Schön G, Katouzi A, Bohlen H, Horn-Lohrens O, Parwaresch R, Diehl V, Lemke H, Engert A. Development of new ricin A-chain immunotoxins with potent anti-tumor effects against human Hodgkin cells in vitro and disseminated Hodgkin tumors in SCID mice using high-affinity monoclonal antibodies directed against the CD30 antigen. Int J Cancer 1995; 63: 238-244.
    • (1995) Int J Cancer , vol.63 , pp. 238-244
    • Schnell, R.1    Linnartz, C.2    Schön, G.3    Katouzi, A.4    Bohlen, H.5    Horn-Lohrens, O.6    Parwaresch, R.7    Diehl, V.8    Lemke, H.9    Engert, A.10
  • 50
    • 0028866012 scopus 로고
    • Cocktails of ricin A-chain immunotoxins against different antigens of Hodgkin and Sternberg-Reed cells have superior anti-tumor effects against H-RS cells in vitro and solid Hodgkin tumors in mice
    • Engert A. Gottstein C, Bohlen H, Winkler U, Schön G, Manske O, Schnell R, Diehl V, Thorpe P. Cocktails of ricin A-chain immunotoxins against different antigens of Hodgkin and Sternberg-Reed cells have superior anti-tumor effects against H-RS cells in vitro and solid Hodgkin tumors in mice. Int J Cancer 1995; 63: 304-309.
    • (1995) Int J Cancer , vol.63 , pp. 304-309
    • Engert, A.1    Gottstein, C.2    Bohlen, H.3    Winkler, U.4    Schön, G.5    Manske, O.6    Schnell, R.7    Diehl, V.8    Thorpe, P.9
  • 51
    • 0023632524 scopus 로고
    • Elimination of T cells from human peripheral blood and bone marrow using a cocktail of three anti-T cell immunotoxins
    • Katz FE, Janossy G, Cumber A, Ross W, Blacklock HA, Tax W, Thorpe PE. Elimination of T cells from human peripheral blood and bone marrow using a cocktail of three anti-T cell immunotoxins. Br J Haematol 1987; 67: 407-411.
    • (1987) Br J Haematol , vol.67 , pp. 407-411
    • Katz, F.E.1    Janossy, G.2    Cumber, A.3    Ross, W.4    Blacklock, H.A.5    Tax, W.6    Thorpe, P.E.7
  • 52
    • 0026803031 scopus 로고
    • The antitumor activity of an anti-CD 22 immunotoxin in SCID mice with disseminated Daudi lymphoma is enhanced by either an anti-CD19 antibody or an anti-CD19 immunotoxin
    • Ghetie MA, Tucker K, Richardson J, Uhr JW, Vitetta ES. The antitumor activity of an anti-CD 22 immunotoxin in SCID mice with disseminated Daudi lymphoma is enhanced by either an anti-CD19 antibody or an anti-CD19 immunotoxin. Blood 1992; 80: 2315-2320.
    • (1992) Blood , vol.80 , pp. 2315-2320
    • Ghetie, M.A.1    Tucker, K.2    Richardson, J.3    Uhr, J.W.4    Vitetta, E.S.5
  • 54
    • 4243522031 scopus 로고    scopus 로고
    • Recombinant immunotoxins for the treatment of Hodgkin's lymphoma
    • Barth S, Engert A. Recombinant immunotoxins for the treatment of Hodgkin's lymphoma. Leuk Lymphoma 1998; 29 (Suppl. 1): O-10.
    • (1998) Leuk Lymphoma , vol.29 , Issue.SUPPL. 1
    • Barth, S.1    Engert, A.2


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