Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells

European Journal of Immunology

Volumn 31, Issue 11, 2001, Pages 3388-3393

  Jarrossay, David ^a   Napolitani, Giorgio ^b   Colonna, Marco ^a   Sallusto, Federica ^b   Lanzavecchia, Antonio ^c  

^a INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Switzerland)

^b CHIRON VACCINES   (Italy)

^c BASEL INSTITUTE FOR IMMUNOLOGY   (Switzerland)

Author keywords

Innate immunity; Interferon; Myeloid dendritic cells; Plasmacytoid dendritic cell; Toll like receptors

Indexed keywords

CHEMOKINE RECEPTOR; CYTOKINE; INTERFERON; TOLL LIKE RECEPTOR;

ARTICLE; BLOOD; BONE MARROW; CELL MATURATION; CELL MIGRATION; CELL SPECIFICITY; CELL STIMULATION; CELL SUBPOPULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; EFFECTOR CELL; HUMAN; HUMAN CELL; LYMPHOID ORGAN; MICROORGANISM; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; T LYMPHOCYTE;

CYTOKINES; DENDRITIC CELLS; DROSOPHILA PROTEINS; HUMANS; MEMBRANE GLYCOPROTEINS; RECEPTORS, CCR5; RECEPTORS, CELL SURFACE; RECEPTORS, CHEMOKINE; TOLL-LIKE RECEPTOR 1; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 9; TOLL-LIKE RECEPTORS; UP-REGULATION;

EID: 0035179882     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200111)31:11<3388::AID-IMMU3388>3.0.CO;2-Q     Document Type: Article

References (38)

1. Dendritic cells and the control of immunity
2. CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs
3. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
4. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
5. Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages
6. Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
7. Cutting edge: Recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2
8. Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2
9. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
10. A Toll-like receptor recognizes bacterial DNA
11. The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors
12. The human toll signaling pathway: Divergence of nuclear factor kappaB and JNK/SAPK activation upstream of tumor necrosis factor receptor- associated factor 6 (TRAF6)
13. The role of toll-like receptors (TLRs) in bacteria-induced maturation of murine dendritic cells (DCS). Peptidoglycan and lipoteichoic acid are inducers of DC maturation and require TLR2
14. Microbial lipopeptides stimulate dendritic cell maturation via Toll-like receptor 2
15. Regulation of Toll-like receptors in human monocytes and dendritic cells
16. Maturation of human dendritic cells by cell wall skeleton of Mycobacterium bovis bacillus Calmette-Guerin: Involvement of toll-like receptors
17. Activation of toll-like receptor 2 on human dendritic cells triggers induction of IL-12, but not IL-10
18. Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: Selective expression of TLR3 in dendritic cells
19. Human blood contains two subsets of dendritic cells, one immunologically mature and the other immature
20. The role of dendritic cells in the induction and regulation of immunity to microbial infection
21. Dendritic cell ontogeny: A human dendritic cell lineage of myeloid origin
22. The nature of the principal type 1 interferon-producing cells in human blood
23. Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon
24. A leukocyte subset bearing HLA-DR antigens is responsible for in vitro alpha interferon production in response to viruses
25. Natural interferon alpha/beta-producing cells link innate and adaptive immunity
26. Plasmacytoid dendritic cells activated by influenza virus and CD40L drive a potent Th1 polarization
27. Reciprocal control of T helper cell and dendritic cell differentiation
28. Plasmacytoid monocytes (so-called plasmacytoid T cells) in Kikuchi's lymphadenitis. An immunohistologic study
29. Biology of chemokine and classical chemo-attractant receptors: Differential requirements for adhesion-triggering versus chemotactic responses in lymphoid cells
30. Distinct CpG DNA and polyinosinic-polycytidylic acid double-stranded RNA, respectively, stimulate CD11c(-) type 2 dendritic cell precursors and CD11c(+) dendritic cells to produce type I IFN
31. Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells
32. T cell priming by type-1 and type-2 polarized dendritic cells: The concept of a third signal
33. Kinetics of dendritic cell activation: Impact on priming of Th1, Th2 and nonpolarized T cells
34. Maturation, activation, and protection of dendritic cells induced by double-stranded RNA
35. Type i interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo
36. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha
37. CpG motifs in bacterial DNA trigger direct B cell activation
38. Real time quantitative PCR