Cutting edge: The dendritic cell cytoskeleton is critical for the formation of the immunological synapse

Journal of Immunology

Volumn 166, Issue 3, 2001, Pages 1452-1456

  Al Alwan, M M ^a   Rowden, G ^a   Lee, T D G ^a   West, K A ^a  

^a Dickson Building ^*  (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; T LYMPHOCYTE RECEPTOR; CYTOCHALASIN D;

ACTIN POLYMERIZATION; ANTIGEN PRESENTING CELL; ARTICLE; CELL INTERACTION; CONTROLLED STUDY; CYTOSKELETON; DENDRITIC CELL; HUMAN; HUMAN CELL; MIXED LYMPHOCYTE REACTION; PRIORITY JOURNAL; SYNAPTOGENESIS; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CELL AGGREGATION; CELL COMMUNICATION; CELL CULTURE; CELL POLARITY; COCULTURE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; IMMUNOLOGY; INTERPHASE; LYMPHOCYTE ACTIVATION; METABOLISM; MIXED LYMPHOCYTE CULTURE; MOUSE; T LYMPHOCYTE SUBPOPULATION;

ACTINS; ANIMALS; CELL AGGREGATION; CELL COMMUNICATION; CELL POLARITY; CELLS, CULTURED; COCULTURE TECHNIQUES; CYTOCHALASIN D; CYTOSKELETON; DENDRITIC CELLS; INTERPHASE; LYMPHOCYTE ACTIVATION; LYMPHOCYTE CULTURE TEST, MIXED; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; T-LYMPHOCYTE SUBSETS;

EID: 0035253596     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.166.3.1452     Document Type: Article

References (23)

1. Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy: Role of T cell actin cytoskeleton
2. The duration of antigenic stimulation determines the fate of naive and effector T cells
3. The immunological synapse: A molecular machine controlling T cell activation
4. The specific interaction of helper T cells and antigen-presenting B cells. IV. Membrane and cytoskeletal reorganizations in the bound T cell as a function of antigen dose
5. Antigen-receptor complex stimulation triggers protein kinase C-dependent CD11a/CD18-cytoskeleton association in T lymphocytes
6. Three-dimensional segregation of supramolecular activation clusters in T cells
7. Effects of cytochalasin and phalloidin on actin
8. Visualizing the dynamics of T cell activation: Intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels
9. Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction
10. Vav regulates peptide-specific apoptosis in thymocytes
11. The immunological synapse and the actin cytoskeleton: Molecular hardware for T cell signaling
12. Distinct features of dendritic cells and anti-Ig activated B cells as stimulators of the primary mixed leukocyte reaction
13. An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow
14. The actin-bundling protein fascin is involved in the formation of dendritic processes in maturing epidermal Langerhans cells
15. Fascin is involved in the antigen presentation activity of mature dendritic cells
16. Accessory cell-T lymphocyte interactions: Antigen-dependent and -independent clustering
17. Jasplakinolide, a cytotoxic natural product, induces actin polymerization and competitively inhibits the binding of phalloidin to F-actin
18. Latrunculinsnovel marine macrolides that disrupt microfilament organization and affect cell growth. I. Comparison with cytochalasin D
19. DC-SIGN: A guide to some mysteries of dendritic cells
20. Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses
21. Clustering with dendritic cells precedes and is essential for T-cell proliferation in a mitogenesis model
22. The requirement for lymphocyte function-associated antigen 1 in homotypic leukocyte adhesion stimulated by phorbol ester
23. Monoclonal antibodies to LFA-1 and to CD4 inhibit the mixed leukocyte reaction after the antigen-dependent clustering of dendritic cells and T lymphocytes