Recognition of autologous dendritic cells by human NK cells

European Journal of Immunology

Volumn 29, Issue 12, 1999, Pages 4022-4029

  Carbone, Ennio ^a,c   Terrazzano, Giuseppe ^a   Ruggiero, Giuseppina ^a   Zanzi, Delia ^a   Ottaiano, Alessandro ^a   Manzo, Ciro ^b   Kärre, Klas ^c   Zappacosta, Serafino ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b NATIONAL CANCER INSTITUTE   (Italy)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

CD40; Cytokine; Dendritic cell; NK

Indexed keywords

ALLOANTIGEN; CD40 ANTIGEN; CD94 ANTIGEN; CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 2; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR ALPHA;

ANTIGEN RECOGNITION; ARTICLE; CELL KILLING; DENDRITIC CELL; EFFECTOR CELL; HUMAN; HUMAN CELL; NATURAL KILLER CELL; PRIORITY JOURNAL; TARGET CELL;

ANTIGEN PRESENTATION; ANTIGENS, CD40; CYTOTOXICITY, IMMUNOLOGIC; DENDRITIC CELLS; GENE TRANSFER TECHNIQUES; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; KILLER CELLS, NATURAL;

EID: 0032759198     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199912)29:12<4022::AID-IMMU4022>3.0.CO;2-O     Document Type: Article

References (32)

1. 2m-bone marrow in chimeric mice. Proc. Natl. Acad. Sci. USA 1991. 88: 10332-10337.
2. Kos, F. J. and Engleman, E. G., Immune regulation: a critical link between NK cells and CTLs. Immunol. Today 1996. 174: 174-176.
3. Medzhitov, R. and Janeway, C. A. Jr., Innate immunity: impact on the adaptive immune response. Curr. Opin. Immunol. 1997. 9: 4-9.
4. Trinchieri, G., Biology of NK cells. Adv. Immunol. 1989. 47: 187-376.
5. Bancroft, G. J., The role of natural killer cells in innate resistence to infection. Curr. Opin. Immunol. 1993. 5: 503-510.
6. Bancroft, G. J., Schreiher, R. D. and Unanue, E. R., Natural immunity a T cell independent pathway of macrophage activation, defined in the SCID mouse. Immunol. Rev. 1991. 124: 5-24.
7. Roake, J. A., Rao, A. S., Morris, P. J., Larsen, C. P., Hankins, D. F. and Austin, J. M., Dendritic cell loss from non lymphoid tissues after systemic administration of lipopolysaccharide, tumor necrosis factor and interleukin 1. J. Exp. Med. 1995. 181: 2237-2246.
8. Sallusto, F., Cella, M., Danieli, C. and Lanzavecchia, A., Dendritic cell use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products. J. Exp. Med. 1995. 182: 389-400.
9. Steinman, R. M., The dendritic cell system and its role in immunogenicity. Annu. Rev. Immunol. 1991. 9: 271-296.
10. + T lymphocytes by human blood dendritic cells in vitro. J. Clin. Invest. 1992. 90: 229-237.
11. Chambers, B. J., Salcedo, M. and Ljunggren, H. G., Triggering of natural killer cells by the costimulatory molecule CD80 (B7-1). Immunity 1996. 5: 311-317.
12. Carbone, E., Ruggiero, G., Terrazzano, G., Palomba, C., Manzo, C., Fontana, S., Spits, H., Kärre, K. and Zappacosta, S., A new mechanism of NK cell cytotoxicity activation: the CD40-CD40 ligand interaction. J. Exp. Med. 1997. 185: 2053-2059.
13. Martin-Fontecha, A., Assarsson, E., Carbone, E., Kärre, K. and Ljunggren, H.-G., Triggering of murine NK cells by CD40 and CD86 (B7-2). J. Immunol. 1999. 162: 5910-5915.
14. Tripp, C. S., Wolf, S. F. and Unanue, E. R., Interleukin 12 and tumor necrosis factor alpha are costimulatory of IFN-γ production by NK cells in SCID mice with listeriosis, and IL-10 is a physiologic antagonist. Proc. Natl. Acad. Sci. USA 1993. 90: 3725-3729.
15. + T-cell subset inhibits antigen specific T cell responses and prevents colitis. Nature 1997. 389: 737-742.
16. Kuhn, R., Lohler, J., Rennick, D., Rajewski, K. and Muller, W., Interleukin 10 deficient mice develop chronic enterocolitis. Cell 1993. 75: 263-274.
17. Buelens, C., Verhasselt, V., De Groote, D., Thielemans, K., Goldman, M. and Willems, F., Interleukin-10 prevents the generation of dendritic cells from human peripheral blood mononuclear cells cultured with IL-4 and granulocyte/macrophage colony stimulating factor. Eur. J. Immunol. 1997. 27: 756-762.
18. Morel, A. S., Quantino, S., Dovek, D. C. and Londei, M., Split activity of IL-10 on antigen capture and antigen presentation by human dendritic cells: definition of a mature step. Eur. J. Immunol. 1997. 27: 26-34.
19. Bancherau, J. and Steinman, R. M., Dendritic cells and the control of immunity. Nature 1998. 392: 245-252.
20. Geldhof, A., Moser, M., Laspaghard, L., Thielemans, K. and De Baetselier, P., Interleukin 12 activated natural killer cells recognise B7 costimulatory molecules on tumor cells and autologous dendritic cells. Blood 1998. 91: 196-206.
21. Shah, P. D., Gilbertson, S. M. and Rowley, D. A., Dendritic cells that have interacted with antigens are targets for natural killer cells. J. Exp. Med. 1985. 162: 624-636.
22. Zhang, B., Yamamura, T., Kondo, T., Fujiwara, M. and Tabira, T., Regulation of experimental autoimmune encephalomyelitis by natural killer J. Exp. Med. 1997. 186: 1677-1687.
23. Allavena, P., Piemonti, L., Longoni, D., Bernasconi, S., Stoppaccino, A., Ruco, L. and Mantovani, A., IL-10 prevents the differentiation of monocytes to dendritic cells but promotes their maturation to macrophages. Eur. J. Immunol. 1998. 28: 359-369.
24. Steinbrick, K., Wölfl, M., Jonuleit, H., Knop, J. and Enk, A., Induction of tolerance by IL-10 treated dendritic cells. J. Immunol. 1997. 1221: 4772-4780.
25. Salazar-Onfray, F., Petersson, M., Franksson, L., Matsuda, M., Blankstein, T., Kärre, K. and Kiessling, K., IL-10 converts mouse lymphomas cells to a CTL resistant NK sensitive phenotype with low but peptide inducible MHC class I expression. J. Immunol. 1995. 154: 6291-6298.
26. Sivori, S., Pende, D., Bottino, C., Marcenaro, E., Pessino, A., Biassoni, R., Moretta, L. and Moretta, A., NKp46 is the major triggering receptor involved in the natural cytotoxicity of fresh or cultured human NK cells. Correlation between surface density of NKp46 and natural cytotoxicity against autologous, allogeneic or xenogeneic target cells. Eur. J. Immunol. 1999. 29: 1656-1666.
27. Pessino, A., Sivori, S., Bottino, C., Malaspina, A., Morelli, L., Moretta, L., Biassoni, R. and Moretta, A., Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity. J. Exp. Med. 1998. 188: 953-960.
28. Salazar-Mather, T. P., Ishikawa, R. and Biron, C. A., NK cell trafficking and cytokine expression in splenic compartments after IFN induction and viral infection. J. Immunol. 1996. 21: 3054-3064.
29. Salazar-Mather, T. P., Orange, J. S. and Biron, C. A., Early murine cytomegalovirus (MCMV) infection induces liver natural killer (NK) cell inflammation and protection through macrophage inflammatory protein 1a dependent pathways. J. Exp. Med. 1998. 187: 1-14.
30. Carson, W. E., Lindemann, M. J., Baiocchi, R., Linett, M., Tan, J. C., Chou, C. C., Narula, S. and Caliguri, M. A., The functional characterization of Interleukin-10 receptor expression on human natural killer cells. Blood 1995. 85: 3577-3585.
31. Sallusto, F. and Lanzavecchia, A., Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin-4 and downregulated by tumor necrosis factor-α. J. Exp. Med. 1994. 179: 1109-1118.
32. Loken, M. R. and Lanier, L. L., Three-color immunofluorescence analysis of Leu antigens on human peripheral blood using two lasers on a fluorescence activated cell sorter. Cytometry 1984. 5: 151-155.