Natural killer cell behavior in lymph nodes revealed by static and real-time imaging

Journal of Experimental Medicine

Volumn 203, Issue 3, 2006, Pages 619-631

  Bajénoff, Marc ^a   Breart, Béatrice ^b   Huang, Alex Y C ^c   Qi, Hai ^c   Cazareth, Julie ^a   Braud, Veronique M ^b   Germain, Ronald N ^c   Glaichenhaus, Nicolas ^a  

^a INSERM   (France)

^b CNRS   (France)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON;

ANIMAL CELL; ARTICLE; BRAIN CORTEX; CELL FUNCTION; CELL INTERACTION; CELL MOTILITY; CELLULAR DISTRIBUTION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; IMAGING; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; LEISHMANIA MAJOR; LEISHMANIASIS; LYMPH NODE; MEDULLA OBLONGATA; MICROSCOPY; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; STEADY STATE; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTERFERON TYPE II; KILLER CELLS, NATURAL; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; LYMPH NODES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; MICROSCOPY, FLUORESCENCE, MULTIPHOTON; SIGNAL TRANSDUCTION;

EID: 33645078915     PISSN: 00221007     EISSN: 00221007     Source Type: Journal    
DOI: 10.1084/jem.20051474     Document Type: Article

References (40)

1. French, A.R., and W.M. Yokoyama. 2003. Natural killer cells and viral infections. Curr. Opin. Immunol. 15:45-51.
2. Yokoyama, W.M., S. Kim, and A.R. French. 2004. The dynamic life of natural killer cells. Annu. Rev. Immunol. 22:405-429.
3. Fernandez, N.C., A. Lozier, C. Flament, P. Ricciardi-Castagnoli, D. Bellet, M. Suter, M. Perricaudet, T. Tursz, E. Maraskovsky, and L. Zitvogel. 1999. Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo. Nat. Med. 5:405-411.
4. Piccioli, D., S. Sbrana, E. Melandri, and N.M. Valiante. 2002. Contact-dependent stimulation and inhibition of dendritic cells by natural killer cells. J. Exp. Med. 195:335-341.
5. Gerosa, F., B. Baldani-Guerra, C. Nisii, V. Marchesini, G. Carra, and G. Trinchieri. 2002. Reciprocal activating interaction between natural killer cells and dendritic cells. J. Exp. Med. 195:327-333.
6. Ferlazzo, G., M.L. Tsang, L. Moretta, G. Melioli, R.M. Steinman, and C. Munz. 2002. Human dendritic cells activate resting natural killer (NK) cells and are recognized via the NKp30 receptor by activated NK cells. J. Exp. Med. 195:343-351.
7. Andrews, D.M., A.A. Scalzo, W.M. Yokoyama, M.J. Smyth, and M.A. Degli-Esposti. 2003. Functional interactions between dendritic cells and NK cells during viral infection. Nat. Immunol. 4:175-181.
8. Fehniger, T.A., M.A. Cooper, G.J. Nuovo, M. Cella, F. Facchetti, M. Colonna, and M.A. Caligiuri. 2003. CD56bright natural killer cells are present in human lymph nodes and are activated by T cell-derived IL-2: a potential new link between adaptive and innate immunity. Blood. 101:3052-3057.
9. Ferlazzo, G., M. Pack, D. Thomas, C. Paludan, D. Schmid, T. Strowig, G. Bougras, W.A. Muller, L. Moretta, and C. Munz. 2004. Distinct roles of IL-12 and IL-15 in human natural killer cell activation by dendritic cells from secondary lymphoid organs. Proc. Natl. Acad. Sci. USA. 101:16606-16611.
10. Martin-Fontecha, A., L.L. Thomsen, S. Brett, C. Gerard, M. Lipp, A. Lanzavecchia, and F. Sallusto. 2004. Induced recruitment of NK cells to lymph nodes provides IFN-gamma for T(H)1 priming. Nat. Immunol. 5:1260-1265.
11. Blaschke, V., B. Micheel, R. Pabst, and J. Westermann. 1995. Lymphocyte traffic through lymph nodes and Peyer's patches of the rat: B- and T-cell-specific migration patterns within the tissue, and their dependence on splenic tissue. Cell Tissue Res. 282:377-386.
12. Gretz, J.E., A.O. Anderson, and S. Shaw. 1997. Cords, channels, corridors and conduits: critical architectural elements facilitating cell interactions in the lymph node cortex. Immunol. Rev. 156:11-24.
13. Gretz, J.E., C.C. Norbury, A.O. Anderson, A.E. Proudfoot, and S. Shaw. 2000. Lymph-borne chemokines and other low molecular weight molecules reach high endothelial venules via specialized conduits while a functional barrier limits access to the lymphocyte microenvironments in lymph node cortex. J. Exp. Med. 192:1425-1440.
14. Baekkevold, E.S., T. Yamanaka, R.T. Palframan, H.S. Carlsen, F.P. Reinholt, U.H. von Andrian, P. Brandtzaeg, and G. Haraldsen. 2001. The CCR7 ligand elc (CCL19) is transcytosed in high endothelial venules and mediates T cell recruitment. J. Exp. Med. 193:1105-1112.
15. Lindquist, R.L., G. Shakhar, D. Dudziak, H. Wardemann, T. Eisenreich, M.L. Dustin, and M.C. Nussenzweig. 2004. Visualizing dendritic cell networks in vivo. Nat. Immunol. 5:1243-1250.
16. Miller, M.J., S.H. Wei, I. Parker, and M.D. Cahalan. 2002. Two-photon imaging of lymphocyte motility and antigen response in intact lymph node. Science. 296:1869-1873.
17. Miller, M.J., S.H. Wei, M.D. Cahalan, and I. Parker. 2003. Autonomous T cell trafficking examined in vivo with intravital two-photon microscopy. Proc. Natl. Acad. Sci. USA. 100:2604-2609.
18. Sacks, D., and N. Noben-Trauth. 2002. The immunology of susceptibility and resistance to Leishmania major in mice. Nat. Rev. Immunol. 2:845-858.
19. Dokun, A.O., D.T. Chu, L. Yang, A.S. Bendelac, and W.M. Yokoyama. 2001. Analysis of in situ NK cell responses during viral infection. J. Immunol. 167:5286-5293.
20. Andrews, D.M., H.E. Farrell, E.H. Densley, A.A. Scalzo, G.R. Shellam, and M.A. Degli-Esposti. 2001. NK 1.1+ cells and murine cytomegalovirus infection: what happens in situ? J. Immunol. 166:1796-1802.
21. Arase, H., T. Saito, J.H. Phillips, and L.L. Lanier. 2001. Cutting edge: the mouse NK cell-associated antigen recognized by DX5 monoclonal antibody is CD49b (alpha 2 integrin, very late antigen-2). J. Immunol. 167:1141-1144.
22. Hemmerich, S., E.C. Butcher, and S.D. Rosen. 1994. Sulfation-dependent recognition of high endothelial venules (HEV)-ligands by L-selectin and MECA 79, and adhesion-blocking monoclonal antibody. J. Exp. Med. 180:2219-2226.
23. Gallatin, W.M., I.L. Weissman, and E.C. Butcher. 1983. A cell-surface molecule involved in organ-specific homing of lymphocytes. Nature. 304: 30-34.
24. Boes, M., J. Cerny, R. Massol, M. Op den Brouw, T. Kirchhausen, J. Chen, and H.L. Ploegh. 2002. T-cell engagement of dendritic cells rapidly rearranges MHC class II transport. Nature. 418:983-988.
25. Mempel, T.R., S.E. Henrickson, and U.H. Von Andrian. 2004. T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases. Nature. 427:154-159.
26. Huang, A.Y., H. Qi, and R.N. Germain. 2004. Illuminating the landscape of in vivo immunity: insights from dynamic in situ imaging of secondary lymphoid tissues. Immunity. 21:331-339.
27. Scharton-Kersten, T., and P. Scott. 1995. The role of the innate immune response in Th1 cell development following Leishmania major infection. J. Leukoc. Biol. 57:515-522.
28. Katakai, T., T. Hara, J.H. Lee, H. Gonda, M. Sugai, and A. Shimizu. 2004. A novel reticular stromal structure in lymph node cortex: an immuno-platform for interactions among dendritic cells, T cells and B cells. Int. Immunol. 16:1133-1142.
29. Bajenoff, M., S. Granjeaud, and S. Guerder. 2003. The strategy of T cell antigen-presenting cell encounter in antigen-draining lymph nodes revealed by imaging of initial T cell activation. J. Exp. Med. 198:715-724.
30. Ferlazzo, G., C. Semino, M. Meta, F. Procopio, B. Morandi, and G. Melioli. 2002. T lymphocytes express B7 family molecules following interaction with dendritic cells and acquire bystander costimulatory properties. Eur. J. Immunol. 32:3092-3101.
31. Moretta, L., R. Biassoni, C. Bottino, M.C. Mingari, and A. Moretta. 2002. Surface receptors that regulate the NK cell function: beyond the NK cell scope. Curr. Top. Microbiol. Immunol. 266:11-22.
32. Granucci, F., I. Zanoni, N. Pavelka, S.L. Van Dommelen, C.E. Andoniou, F. Belardelli, M.A. Degli Esposti, and P. Ricciardi-Castagnoli. 2004. A contribution of mouse dendritic cell-derived IL-2 for NK cell activation. J. Exp. Med. 200:287-295.
33. Ranson, T., C.A. Vosshenrich, E. Corcuff, O. Richard, W. Muller, and J.P. Di Santo. 2003. IL-15 is an essential mediator of peripheral NK-cell homeostasis. Blood. 101:4887-4893.
34. Cooper, M.A., J.E. Bush, T.A. Fehniger, J.B. VanDeusen, R.E. Waite, Y. Liu, H.L. Aguila, and M.A. Caligiuri. 2002. In vivo evidence for a dependence on interleukin 15 for survival of natural killer cells. Blood. 100:3633-3638.
35. Stetson, D.B., M. Mohrs, R.L. Reinhardt, J.L. Baron, Z.E. Wang, L. Gapin, M. Kronenberg, and R.M. Locksley. 2003. Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function. J. Exp. Med. 198:1069-1076.
36. Tato, C.M., G.A. Martins, F.A. High, C.B. DiCioccio, S.L. Reiner, and C.A. Hunter. 2004. Cutting edge: innate production of IFN-gamma by NK cells is independent of epigenetic modification of the IFN-gamma promoter. J. Immunol. 173:1514-1517.
37. Moretta, A. 2002. Natural killer cells and dendritic cells: rendezvous in abused tissues. Nat. Rev. Immunol. 2:957-964.
38. Scharton, T.M., and P. Scott. 1993. Natural killer cells are a source of interferon γ that drives differentiation of CD4+ T cell subsets and induces early resistance to Leishmania major in mice. J. Exp. Med. 178:567-577.
39. Wang, Q., L. Malherbe, D. Zhang, K. Zingler, N. Glaichenhaus, and N. Killeen. 2001. CD4 promotes breadth in the TCR repertoire. J. Immunol. 167:4311-4320.
40. Bajenoff, M., and S. Guerder. 2003. Homing to nonlymphoid tissues is not necessary for effector Th1 cell differentiation. J. Immunol. 171:6355-6362.